-
1
-
-
74349100743
-
Analysis of the intermediary metabolism of a reductive chemoautotroph
-
Srinivasan V, Morowitz HJ, (2009) Analysis of the intermediary metabolism of a reductive chemoautotroph. Biol Bull 217: 222-232.
-
(2009)
Biol Bull
, vol.217
, pp. 222-232
-
-
Srinivasan, V.1
Morowitz, H.J.2
-
2
-
-
0030668554
-
The natural selection of the chemical elements
-
Williams RJ, (1997) The natural selection of the chemical elements. Cell Mol Life Sci 53: 816-829.
-
(1997)
Cell Mol Life Sci
, vol.53
, pp. 816-829
-
-
Williams, R.J.1
-
3
-
-
0024893581
-
Homeotopic transformation and the origin of translation
-
Danchin A, (1989) Homeotopic transformation and the origin of translation. Prog Biophys Mol Biol 54: 81-86.
-
(1989)
Prog Biophys Mol Biol
, vol.54
, pp. 81-86
-
-
Danchin, A.1
-
4
-
-
0024254814
-
Before enzymes and templates: theory of surface metabolism
-
Wachtershauser G, (1988) Before enzymes and templates: theory of surface metabolism. Microbiol Rev 52: 452-484.
-
(1988)
Microbiol Rev
, vol.52
, pp. 452-484
-
-
Wachtershauser, G.1
-
5
-
-
77952888917
-
Autotrophic carbon fixation in archaea
-
Berg IA, Kockelkorn D, Ramos-Vera WH, Say RF, Zarzycki J, et al. (2010) Autotrophic carbon fixation in archaea. Nat Rev Microbiol 8: 447-460.
-
(2010)
Nat Rev Microbiol
, vol.8
, pp. 447-460
-
-
Berg, I.A.1
Kockelkorn, D.2
Ramos-Vera, W.H.3
Say, R.F.4
Zarzycki, J.5
-
7
-
-
33645015786
-
Predicting physiological concentrations of metabolites from their molecular structure
-
Liebermeister W, (2005) Predicting physiological concentrations of metabolites from their molecular structure. J Comput Biol 12: 1307-1315.
-
(2005)
J Comput Biol
, vol.12
, pp. 1307-1315
-
-
Liebermeister, W.1
-
8
-
-
68049100110
-
Absolute metabolite concentrations and implied enzyme active site occupancy in Escherichia coli
-
Bennett BD, Kimball EH, Gao M, Osterhout R, Van Dien SJ, et al. (2009) Absolute metabolite concentrations and implied enzyme active site occupancy in Escherichia coli. Nat Chem Biol 5: 593-599.
-
(2009)
Nat Chem Biol
, vol.5
, pp. 593-599
-
-
Bennett, B.D.1
Kimball, E.H.2
Gao, M.3
Osterhout, R.4
van Dien, S.J.5
-
9
-
-
34247612307
-
Multiple high-throughput analyses monitor the response of E. coli to perturbations
-
Ishii N, Nakahigashi K, Baba T, Robert M, Soga T, et al. (2007) Multiple high-throughput analyses monitor the response of E. coli to perturbations. Science 316: 593-597.
-
(2007)
Science
, vol.316
, pp. 593-597
-
-
Ishii, N.1
Nakahigashi, K.2
Baba, T.3
Robert, M.4
Soga, T.5
-
10
-
-
66149122635
-
High-throughput quantitative metabolomics: workflow for cultivation, quenching, and analysis of yeast in a multiwell format
-
Ewald JC, Heux S, Zamboni N, (2009) High-throughput quantitative metabolomics: workflow for cultivation, quenching, and analysis of yeast in a multiwell format. Anal Chem 81: 3623-3629.
-
(2009)
Anal Chem
, vol.81
, pp. 3623-3629
-
-
Ewald, J.C.1
Heux, S.2
Zamboni, N.3
-
11
-
-
77951125481
-
Tradeoff between enzyme and metabolite efficiency maintains metabolic homeostasis upon perturbations in enzyme capacity
-
Fendt SM, Buescher JM, Rudroff F, Picotti P, Zamboni N, et al. (2010) Tradeoff between enzyme and metabolite efficiency maintains metabolic homeostasis upon perturbations in enzyme capacity. Mol Syst Biol 6: 356.
-
(2010)
Mol Syst Biol
, vol.6
, pp. 356
-
-
Fendt, S.M.1
Buescher, J.M.2
Rudroff, F.3
Picotti, P.4
Zamboni, N.5
-
12
-
-
77950905613
-
Differential glucose repression in common yeast strains in response to HXK2 deletion
-
Kummel A, Ewald JC, Fendt SM, Jol SJ, Picotti P, et al. (2010) Differential glucose repression in common yeast strains in response to HXK2 deletion. FEMS Yeast Res 10: 322-332.
-
(2010)
FEMS Yeast Res
, vol.10
, pp. 322-332
-
-
Kummel, A.1
Ewald, J.C.2
Fendt, S.M.3
Jol, S.J.4
Picotti, P.5
-
13
-
-
76249130402
-
Metabolic fluxes during strong carbon catabolite repression by malate in Bacillus subtilis
-
Kleijn RJ, Buescher JM, Le Chat L, Jules M, Aymerich S, et al. (2010) Metabolic fluxes during strong carbon catabolite repression by malate in Bacillus subtilis. J Biol Chem 285: 1587-1596.
-
(2010)
J Biol Chem
, vol.285
, pp. 1587-1596
-
-
Kleijn, R.J.1
Buescher, J.M.2
Le Chat, L.3
Jules, M.4
Aymerich, S.5
-
14
-
-
0016220406
-
Intracellular free amino acid concentration in human muscle tissue
-
Bergstrom J, Furst P, Noree LO, Vinnars E, (1974) Intracellular free amino acid concentration in human muscle tissue. J Appl Physiol 36: 693-697.
-
(1974)
J Appl Physiol
, vol.36
, pp. 693-697
-
-
Bergstrom, J.1
Furst, P.2
Noree, L.O.3
Vinnars, E.4
-
15
-
-
11144324238
-
Quantitative analysis of the microbial metabolome by isotope dilution mass spectrometry using uniformly 13C-labeled cell extracts as internal standards
-
Wu L, Mashego MR, van Dam JC, Proell AM, Vinke JL, et al. (2005) Quantitative analysis of the microbial metabolome by isotope dilution mass spectrometry using uniformly 13C-labeled cell extracts as internal standards. Anal Biochem 336: 164-171.
-
(2005)
Anal Biochem
, vol.336
, pp. 164-171
-
-
Wu, L.1
Mashego, M.R.2
van Dam, J.C.3
Proell, A.M.4
Vinke, J.L.5
-
16
-
-
0029021581
-
Co-inertia analysis of amino-acid physico-chemical properties and protein composition with the ADE package
-
Thioulouse J, Lobry JR, (1995) Co-inertia analysis of amino-acid physico-chemical properties and protein composition with the ADE package. Comput Appl Biosci 11: 321-329.
-
(1995)
Comput Appl Biosci
, vol.11
, pp. 321-329
-
-
Thioulouse, J.1
Lobry, J.R.2
-
18
-
-
71249143374
-
Water-Hydrophobic Compound Interactions with the Microbial Cell
-
In: Timmis K, editors
-
McCammick E, Gomase V, McGenity T, Timson D, Hallsworth J, (2010) Water-Hydrophobic Compound Interactions with the Microbial Cell In: Timmis K, editors. Handbook of Hydrocarbon and Lipid Microbiology.
-
(2010)
Handbook of Hydrocarbon and Lipid Microbiology
-
-
McCammick, E.1
Gomase, V.2
McGenity, T.3
Timson, D.4
Hallsworth, J.5
-
19
-
-
0035289779
-
Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings
-
Lipinski CA, Lombardo F, Dominy BW, Feeney PJ, (2001) Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings. Adv Drug Deliv Rev 46: 3-26.
-
(2001)
Adv Drug Deliv Rev
, vol.46
, pp. 3-26
-
-
Lipinski, C.A.1
Lombardo, F.2
Dominy, B.W.3
Feeney, P.J.4
-
20
-
-
0032696606
-
Effect of molecular charge on intestinal epithelial drug transport: pH-dependent transport of cationic drugs
-
Palm K, Luthman K, Ros J, Grasjo J, Artursson P, (1999) Effect of molecular charge on intestinal epithelial drug transport: pH-dependent transport of cationic drugs. J Pharmacol Exp Ther 291: 435-443.
-
(1999)
J Pharmacol Exp Ther
, vol.291
, pp. 435-443
-
-
Palm, K.1
Luthman, K.2
Ros, J.3
Grasjo, J.4
Artursson, P.5
-
21
-
-
0141923641
-
Identification and prediction of promiscuous aggregating inhibitors among known drugs
-
Seidler J, McGovern SL, Doman TN, Shoichet BK, (2003) Identification and prediction of promiscuous aggregating inhibitors among known drugs. J Med Chem 46: 4477-4486.
-
(2003)
J Med Chem
, vol.46
, pp. 4477-4486
-
-
Seidler, J.1
McGovern, S.L.2
Doman, T.N.3
Shoichet, B.K.4
-
22
-
-
23844500772
-
High-throughput assays for promiscuous inhibitors
-
Feng BY, Shelat A, Doman TN, Guy RK, Shoichet BK, (2005) High-throughput assays for promiscuous inhibitors. Nat Chem Biol 1: 146-148.
-
(2005)
Nat Chem Biol
, vol.1
, pp. 146-148
-
-
Feng, B.Y.1
Shelat, A.2
Doman, T.N.3
Guy, R.K.4
Shoichet, B.K.5
-
23
-
-
64549152003
-
Promiscuous aggregate-based inhibitors promote enzyme unfolding
-
Coan KE, Maltby DA, Burlingame AL, Shoichet BK, (2009) Promiscuous aggregate-based inhibitors promote enzyme unfolding. J Med Chem 52: 2067-2075.
-
(2009)
J Med Chem
, vol.52
, pp. 2067-2075
-
-
Coan, K.E.1
Maltby, D.A.2
Burlingame, A.L.3
Shoichet, B.K.4
-
24
-
-
33645665186
-
Synergy and antagonism of promiscuous inhibition in multiple-compound mixtures
-
Feng BY, Shoichet BK, (2006) Synergy and antagonism of promiscuous inhibition in multiple-compound mixtures. J Med Chem 49: 2151-2154.
-
(2006)
J Med Chem
, vol.49
, pp. 2151-2154
-
-
Feng, B.Y.1
Shoichet, B.K.2
-
25
-
-
0141858715
-
The specificity of cross-reactivity: promiscuous antibody binding involves specific hydrogen bonds rather than nonspecific hydrophobic stickiness
-
James LC, Tawfik DS, (2003) The specificity of cross-reactivity: promiscuous antibody binding involves specific hydrogen bonds rather than nonspecific hydrophobic stickiness. Protein Sci 12: 2183-2193.
-
(2003)
Protein Sci
, vol.12
, pp. 2183-2193
-
-
James, L.C.1
Tawfik, D.S.2
-
26
-
-
59849106371
-
Protein promiscuity and its implications for biotechnology
-
Nobeli I, Favia AD, Thornton JM, (2009) Protein promiscuity and its implications for biotechnology. Nat Biotechnol 27: 157-167.
-
(2009)
Nat Biotechnol
, vol.27
, pp. 157-167
-
-
Nobeli, I.1
Favia, A.D.2
Thornton, J.M.3
-
27
-
-
84980187094
-
Hydrophobic Stacking of Bases and the Solvent Denaturation of DNA
-
Sínanoĝlu O, Abdulnur S, (1964) Hydrophobic Stacking of Bases and the Solvent Denaturation of DNA. Photochem Photobiol 3: 333-342.
-
(1964)
Photochem Photobiol
, vol.3
, pp. 333-342
-
-
Sínanoĝlu, O.1
Abdulnur, S.2
-
28
-
-
17644367506
-
Structure-reactivity studies of serum paraoxonase PON1 suggest that its native activity is lactonase
-
Khersonsky O, Tawfik DS, (2005) Structure-reactivity studies of serum paraoxonase PON1 suggest that its native activity is lactonase. Biochemistry 44: 6371-6382.
-
(2005)
Biochemistry
, vol.44
, pp. 6371-6382
-
-
Khersonsky, O.1
Tawfik, D.S.2
-
30
-
-
0346555269
-
Optimization of specificity in a cellular protein interaction network by negative selection
-
Zarrinpar A, Park SH, Lim WA, (2003) Optimization of specificity in a cellular protein interaction network by negative selection. Nature 426: 676-680.
-
(2003)
Nature
, vol.426
, pp. 676-680
-
-
Zarrinpar, A.1
Park, S.H.2
Lim, W.A.3
-
31
-
-
0000398347
-
Empirical Correlation Between Hydrophobic Free Energy and Aqueous Cavity Surface Area
-
Reynolds JA, Gilbert DB, Tanford C, (1974) Empirical Correlation Between Hydrophobic Free Energy and Aqueous Cavity Surface Area. Proc Natl Acad Sci U S A 71: 2925-2927.
-
(1974)
Proc Natl Acad Sci U S A
, vol.71
, pp. 2925-2927
-
-
Reynolds, J.A.1
Gilbert, D.B.2
Tanford, C.3
-
32
-
-
41249091782
-
Pybel: a Python wrapper for the OpenBabel cheminformatics toolkit
-
O'Boyle NM, Morley C, Hutchison GR, (2008) Pybel: a Python wrapper for the OpenBabel cheminformatics toolkit. Chem Cent J 2: 5.
-
(2008)
Chem Cent J
, vol.2
, pp. 5
-
-
O'Boyle, N.M.1
Morley, C.2
Hutchison, G.R.3
-
33
-
-
0003818541
-
Structure and Mechanism in Protein Science: A Guide to Enzyme Catalysis and Protein Folding
-
New York, W. H. Freeman
-
Fersht A, (1998) Structure and Mechanism in Protein Science: A Guide to Enzyme Catalysis and Protein Folding. New York W. H. Freeman.
-
(1998)
-
-
Fersht, A.1
-
34
-
-
10944261243
-
Understanding noncovalent interactions: ligand binding energy and catalytic efficiency from ligand-induced reductions in motion within receptors and enzymes
-
Williams DH, Stephens E, O'Brien DP, Zhou M, (2004) Understanding noncovalent interactions: ligand binding energy and catalytic efficiency from ligand-induced reductions in motion within receptors and enzymes. Angew Chem Int Ed Engl 43: 6596-6616.
-
(2004)
Angew Chem Int Ed Engl
, vol.43
, pp. 6596-6616
-
-
Williams, D.H.1
Stephens, E.2
O'Brien, D.P.3
Zhou, M.4
-
35
-
-
0015866154
-
Environment and exposure to solvent of protein atoms. Lysozyme and insulin
-
Shrake A, Rupley JA, (1973) Environment and exposure to solvent of protein atoms. Lysozyme and insulin. J Mol Biol 79: 351-371.
-
(1973)
J Mol Biol
, vol.79
, pp. 351-371
-
-
Shrake, A.1
Rupley, J.A.2
-
36
-
-
0021755764
-
Solvent accessible surface area and excluded volume in proteins. Analytical equations for overlapping spheres and implications for the hydrophobic effect
-
Richmond TJ, (1984) Solvent accessible surface area and excluded volume in proteins. Analytical equations for overlapping spheres and implications for the hydrophobic effect. J Mol Biol 178: 63-89.
-
(1984)
J Mol Biol
, vol.178
, pp. 63-89
-
-
Richmond, T.J.1
-
37
-
-
37249091134
-
Computation of octanol-water partition coefficients by guiding an additive model with knowledge
-
Cheng T, Zhao Y, Li X, Lin F, Xu Y, et al. (2007) Computation of octanol-water partition coefficients by guiding an additive model with knowledge. J Chem Inf Model 47: 2140-2148.
-
(2007)
J Chem Inf Model
, vol.47
, pp. 2140-2148
-
-
Cheng, T.1
Zhao, Y.2
Li, X.3
Lin, F.4
Xu, Y.5
-
38
-
-
0036757804
-
Application of associative neural networks for prediction of lipophilicity in ALOGPS 2.1 program
-
Tetko IV, Tanchuk VY, (2002) Application of associative neural networks for prediction of lipophilicity in ALOGPS 2.1 program. J Chem Inf Comput Sci 42: 1136-1145.
-
(2002)
J Chem Inf Comput Sci
, vol.42
, pp. 1136-1145
-
-
Tetko, I.V.1
Tanchuk, V.Y.2
-
39
-
-
0035733108
-
The control of the false discovery rate in multiple testing under dependency
-
Benjamini Y, Daniel Y, (2001) The control of the false discovery rate in multiple testing under dependency. Ann Stat 29: 1165-1188.
-
(2001)
Ann Stat
, vol.29
, pp. 1165-1188
-
-
Benjamini, Y.1
Daniel, Y.2
|