Catalytic versatility and backups in enzyme active sites: The case of serum paraoxonase 1

Journal of Molecular Biology

Volumn 418, Issue 3-4, 2012, Pages 181-196

  Ben David, Moshe ^a   Elias, Mikael ^a   Filippi, Jean Jacques ^b   Duñach, Elisabet ^b   Silman, Israel ^a   Sussman, Joel L ^a   Tawfik, Dan S ^a  

^a WEIZMANN INSTITUTE OF SCIENCE   (Israel)

^b UNIVERSITÉ CÔTE D'AZUR   (France)

Author keywords

catalytic promiscuity; conformational diversity; enzyme catalysis; enzyme promiscuity; structural dynamics

Indexed keywords

ARYLDIALKYLPHOSPHATASE 1; LACTONE DERIVATIVE; PHOSPHOTRIESTERASE;

ARTICLE; CATALYSIS; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME MECHANISM; ENZYME STRUCTURE; MOLECULAR DOCKING; PH; PRIORITY JOURNAL; PROTEIN HYDROLYSIS;

MAMMALIA;

EID: 84859267247     PISSN: 00222836     EISSN: 10898638     Source Type: Journal    
DOI: 10.1016/j.jmb.2012.02.042     Document Type: Article

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