The evolutionary origins and catalytic importance of conserved electrostatic networks within TIM-barrel proteins

Protein Science

Volumn 14, Issue 5, 2005, Pages 1158-1170

  Livesay, Dennis R ^a   La, David ^a  

^a CALIFORNIA STATE POLYTECHNIC UNIVERSITY   (United States)

Author keywords

Electrostatic networks; Phylogenetic motifs; Protein family evolution; Residue pKa; TIM barrel proteins

Indexed keywords

5,10 METHYLENETETRAHYDROFOLATE REDUCTASE (FADH2); DIHYDROOROTASE; ENOLASE; FRUCTOSE BISPHOSPHATE ALDOLASE; TRANSALDOLASE; TRIOSEPHOSPHATE ISOMERASE;

AMINO ACID SEQUENCE; ARTICLE; CATALYSIS; ELECTRICITY; ENZYME METABOLISM; PHYLOGENY; PKA; PRIORITY JOURNAL; PROTEIN FAMILY; PROTEIN INTERACTION; PROTEIN MOTIF; RESIDUE ANALYSIS;

AMINO ACID SEQUENCE; CATALYSIS; ELECTROSTATICS; EVOLUTION, MOLECULAR; MOLECULAR SEQUENCE DATA; PHYLOGENY; PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 17744397525     PISSN: 09618368     EISSN: None     Source Type: Journal    
DOI: 10.1110/ps.041221105     Document Type: Article

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