Differential Effects of Glycyrrhiza Species on Genotoxic Estrogen Metabolism: Licochalcone a Downregulates P450 1B1, whereas Isoliquiritigenin Stimulates It

Chemical Research in Toxicology

Volumn 28, Issue 8, 2015, Pages 1584-1594

  Dunlap, Tareisha L ^a   Wang, Shuai ^a   Simmler, Charlotte ^a   Chen, Shao Nong ^a   Pauli, Guido F ^a   Dietz, Birgit M ^a   Bolton, Judy L ^a  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; AROMATIC HYDROCARBON RECEPTOR; CYTOCHROME P450 1B1; ESTROGEN; GAMMA INTERFERON; INDUCIBLE NITRIC OXIDE SYNTHASE; ISOLIQUIRITIGENIN; LICOCHALCONE A; LIQUIRITIGENIN; LUCIFERASE; TUMOR NECROSIS FACTOR ALPHA; CHALCONE DERIVATIVE; CYTOCHROME P450 1A1; PLANT MEDICINAL PRODUCT;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; BREAST EPITHELIUM CELL; CONTROLLED STUDY; DIET SUPPLEMENTATION; ENZYME ACTIVITY; ENZYME INHIBITION; ESTROGEN METABOLISM; GENE EXPRESSION; GLYCYRRHIZA; GLYCYRRHIZA GLABRA; GLYCYRRHIZA INFLATA; GLYCYRRHIZA URALENSIS; HUMAN; HUMAN CELL; IC50; LIQUID CHROMATOGRAPHY; LIQUID CHROMATOGRAPHY TANDEM MASS SPECTROMETRY; MACROPHAGE; NONHUMAN; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; TANDEM MASS SPECTROMETRY; XENOBIOTIC METABOLISM; BIOLOGICAL MODEL; BREAST TUMOR; CHEMISTRY; CYTOLOGY; DOWN REGULATION; DRUG EFFECTS; FEMALE; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; SPECIES DIFFERENCE; UPREGULATION;

GLYCYRRHIZA; GLYCYRRHIZA GLABRA; GLYCYRRHIZA INFLATA; GLYCYRRHIZA URALENSIS;

BREAST NEOPLASMS; CHALCONES; CHROMATOGRAPHY, LIQUID; CYTOCHROME P-450 CYP1A1; DOWN-REGULATION; ESTROGENS; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GLYCYRRHIZA; HUMANS; MACROPHAGES; MODELS, BIOLOGICAL; PLANT PREPARATIONS; SPECIES SPECIFICITY; UP-REGULATION;

EID: 84939236893     PISSN: 0893228X     EISSN: 15205010     Source Type: Journal    
DOI: 10.1021/acs.chemrestox.5b00157     Document Type: Article

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