Mechanisms of estrogen carcinogenesis: The role of E2/E1-quinone metabolites suggests new approaches to preventive intervention - A review

Steroids

Volumn 99, Issue Part A, 2015, Pages 56-60

  Yager, James D ^a  

^a JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

Breast cancer; Chemoprevention; DNA damage; Estrogen; Estrogen quinone adducts; Sulforaphane

Indexed keywords

ADENINE; ANTIESTROGEN; CATECHOL METHYLTRANSFERASE; CATECHOL METHYLTRANSFERASE INHIBITOR; CYTOCHROME P450 1B1; ESTRADIOL; ESTROGEN; ESTROGEN RECEPTOR; ESTRONE; GLUTATHIONE TRANSFERASE A1; GUANINE; KELCH LIKE ECH ASSOCIATED PROTEIN 1; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE); REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE) 1; RESVERATROL; SULFORAPHANE; TRANSCRIPTION FACTOR NRF2; TUMOR MARKER; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; CARCINOGEN; ISOTHIOCYANIC ACID DERIVATIVE; SULFORAFAN;

AEROBIC METABOLISM; ARTICLE; BREAST CANCER; BREAST CARCINOGENESIS; CANCER INHIBITION; CELL PROLIFERATION; DNA ADDUCT; DNA DAMAGE; ENZYME ACTIVITY; ESTROGEN METABOLISM; GENE EXPRESSION; HUMAN; NONHUMAN; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; WESTERN BLOTTING; ANIMAL; BREAST NEOPLASMS; DISEASE MODEL; FEMALE; KIDNEY NEOPLASMS; METABOLISM; MOUSE; RAT; RISK FACTOR; UTERINE NEOPLASMS;

CRICETINAE; MUS; RATTUS;

ANIMALS; ANTICARCINOGENIC AGENTS; BREAST NEOPLASMS; CARCINOGENS; DISEASE MODELS, ANIMAL; ESTRADIOL; ESTROGENS; ESTRONE; FEMALE; HUMANS; ISOTHIOCYANATES; KIDNEY NEOPLASMS; MICE; RATS; RISK FACTORS; UTERINE NEOPLASMS;

EID: 84929838814     PISSN: 0039128X     EISSN: 18785867     Source Type: Journal    
DOI: 10.1016/j.steroids.2014.08.006     Document Type: Review

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