A protective mechanism of licorice (Glycyrrhiza uralensis): Isoliquiritigenin stimulates detoxification system via Nrf2 activation

Journal of Ethnopharmacology

Volumn 162, Issue , 2015, Pages 134-139

  Gong, Hui ^a,b   Zhang, Bi Kui ^a,b   Yan, Miao ^a,b   Fang, Ping Fei ^a,b   Li, Huan De ^a,b   Hu, Chun Ping ^c   Yang, Yang ^c   Cao, Peng ^a,c   Jiang, Pei ^a,b   Fan, Xin Rong ^d  

^a CENTRAL SOUTH UNIVERSITY   (China)

^b CENTRAL SOUTH UNIVERSITY   (China)

^c Laboratory of Translational Medicine   (China)

^d INSTITUTE OF CHINESE MATERIA MEDICA   (China)

Author keywords

Detoxification; Glycyrrhiza uralensis; Isoliquiritigenin; Licorice; Nrf2

Indexed keywords

BILE SALT EXPORT PUMP; GLUCURONOSYLTRANSFERASE 1A1; GLUTAMATE CYSTEINE LIGASE; GLYCYRRHETINIC ACID; GLYCYRRHIZA URALENSIS EXTRACT; ISOLIQUIRITIGENIN; LIQUIRITIGENIN; LIQUIRITIN; MULTIDRUG RESISTANCE PROTEIN 2; TRANSCRIPTION FACTOR NRF2; ABC TRANSPORTER; ABCB11 PROTEIN, MOUSE; CHALCONE DERIVATIVE; FLAVANONE DERIVATIVE; GCLM PROTEIN, MOUSE; GLUCOSIDE; GLUCURONOSYLTRANSFERASE; MESSENGER RNA; MULTIDRUG RESISTANCE PROTEIN; MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 2; NFE2L2 PROTEIN, MOUSE; RENILLA LUCIFERIN 2 MONOOXYGENASE; UGT1A1 ENZYME;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DETOXIFICATION; DRUG METABOLISM; ENZYME ACTIVATION; FEMALE; GLYCYRRHIZA URALENSIS; HEPG2 CELL LINE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; KNOCKOUT MOUSE; LUCIFERASE ASSAY; MOUSE; NONHUMAN; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; UPREGULATION; ANIMAL; ANTIOXIDANT RESPONSIVE ELEMENT; GENETICS; INSTITUTE FOR CANCER RESEARCH MOUSE; METABOLISM;

FABACEAE; GLYCYRRHIZA; GLYCYRRHIZA URALENSIS; MUS;

ANIMALS; ANTIOXIDANT RESPONSE ELEMENTS; ATP-BINDING CASSETTE TRANSPORTERS; CHALCONES; FEMALE; FLAVANONES; GLUCOSIDES; GLUCURONOSYLTRANSFERASE; GLUTAMATE-CYSTEINE LIGASE; GLYCYRRHETINIC ACID; GLYCYRRHIZA URALENSIS; HEP G2 CELLS; HUMANS; LUCIFERASES, RENILLA; MICE, INBRED ICR; MICE, KNOCKOUT; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; NF-E2-RELATED FACTOR 2; RNA, MESSENGER;

EID: 84921419288     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2014.12.043     Document Type: Article

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