Docking and virtual screening strategies for GPCR drug discovery

Methods in Molecular Biology

Volumn 1335, Issue , 2015, Pages 251-276

  Beuming, Thijs ^a   Lenselink, Bart ^a   Pala, Daniele ^a   McRobb, Fiona ^a   Repasky, Matt ^a   Sherman, Woody ^a  

^a NONE

Author keywords

Docking; G protein coupled receptors; Glide; Induced fit docking; Prime; Virtual screening

Indexed keywords

G PROTEIN COUPLED RECEPTOR; LIGAND; WATER;

ALGORITHM; ARTICLE; BINDING SITE; CONFORMATION; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; DRUG DEVELOPMENT; GAS; LIGAND BINDING; MOLECULAR DOCKING; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN STRUCTURE; SCREENING; AGONISTS; ANTAGONISTS AND INHIBITORS; CHEMISTRY; COMPUTER INTERFACE; HUMAN; INVERSE AGONISM; METABOLISM; PRECLINICAL STUDY; PROCEDURES;

DRUG EVALUATION, PRECLINICAL; DRUG INVERSE AGONISM; HUMANS; LIGANDS; MOLECULAR DOCKING SIMULATION; RECEPTORS, G-PROTEIN-COUPLED; USER-COMPUTER INTERFACE; WATER;

EID: 84938883895     PISSN: 10643745     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-4939-2914-6_17     Document Type: Article

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