Assessment and Challenges of Ligand Docking into Comparative Models of G-Protein Coupled Receptors

PLoS ONE

Volumn 8, Issue 7, 2013, Pages

  Nguyen, Elizabeth Dong ^a   Norn, Christoffer ^b,c   Frimurer, Thomas M ^b,c   Meiler, Jens ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b University of Copenhagen   (Denmark)

^c University of Copenhagen   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE A2A RECEPTOR; BETA 1 ADRENERGIC RECEPTOR; BETA 2 ADRENERGIC RECEPTOR; CHEMOKINE RECEPTOR CXCR4; DELTA OPIATE RECEPTOR; DOPAMINE 3 RECEPTOR; G PROTEIN COUPLED RECEPTOR; HISTAMINE H1 RECEPTOR; KAPPA OPIATE RECEPTOR; MU OPIATE RECEPTOR; MUSCARINIC M2 RECEPTOR; MUSCARINIC M3 RECEPTOR; NOCICEPTIN RECEPTOR; RHODOPSIN; SPHINGOSINE 1 PHOSPHATE RECEPTOR;

AMINO ACID SEQUENCE; ARTICLE; COMPUTER PROGRAM; CORRELATION ANALYSIS; CRYSTALLIZATION; FILTRATION; LIGAND BINDING; MOLECULAR DOCKING; MOLECULAR MODEL; MONTE CARLO METHOD; PREDICTION; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN INTERACTION; PROTEIN SECONDARY STRUCTURE; PROTEIN STRUCTURE; SEQUENCE ALIGNMENT;

AMINO ACID SEQUENCE; BINDING SITES; DATABASES, PROTEIN; HUMANS; LIGANDS; MOLECULAR DOCKING SIMULATION; MOLECULAR SEQUENCE DATA; MONTE CARLO METHOD; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; RECEPTORS, G-PROTEIN-COUPLED; SOFTWARE; STRUCTURAL HOMOLOGY, PROTEIN; THERMODYNAMICS;

EID: 84879770850     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0067302     Document Type: Article

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