-
1
-
-
0017177903
-
Hypothermia and intolerance to cold induced by intracisternal administration of the hypothalamic peptide neurotensin
-
Bissette G, Nemeroff CB, Loosen PT, Prange AJ, Jr., Lipton MA (1976) Hypothermia and intolerance to cold induced by intracisternal administration of the hypothalamic peptide neurotensin. Nature 262(5569):607-609.
-
(1976)
Nature
, vol.262
, Issue.5569
, pp. 607-609
-
-
Bissette, G.1
Nemeroff, C.B.2
Loosen, P.T.3
Prange Jr., A.J.4
Lipton, M.A.5
-
2
-
-
0034988344
-
Increased plasma neurotensin concentrations in patients with Parkinson's disease
-
Schimpff RM, et al. (2001) Increased plasma neurotensin concentrations in patients with Parkinson's disease. J Neurol Neurosurg Psychiatry 70(6):784-786.
-
(2001)
J Neurol Neurosurg Psychiatry
, vol.70
, Issue.6
, pp. 784-786
-
-
Schimpff, R.M.1
-
3
-
-
77956236603
-
Neurotensin receptor 1 determines the outcome of non-small cell lung cancer
-
Alifano M, et al. (2010) Neurotensin receptor 1 determines the outcome of non-small cell lung cancer. Clin Cancer Res 16(17):4401-4410.
-
(2010)
Clin Cancer Res
, vol.16
, Issue.17
, pp. 4401-4410
-
-
Alifano, M.1
-
4
-
-
84861850317
-
Neuropeptide receptor ligands as drugs for psychiatric diseases: The end of the beginning?
-
Griebel G, Holsboer F (2012) Neuropeptide receptor ligands as drugs for psychiatric diseases: The end of the beginning? Nat Rev Drug Discov 11(6):462-478.
-
(2012)
Nat Rev Drug Discov
, vol.11
, Issue.6
, pp. 462-478
-
-
Griebel, G.1
Holsboer, F.2
-
5
-
-
0025345759
-
Structure and functional expression of the cloned rat neurotensin receptor
-
Tanaka K, Masu M, Nakanishi S (1990) Structure and functional expression of the cloned rat neurotensin receptor. Neuron 4(6):847-854.
-
(1990)
Neuron
, vol.4
, Issue.6
, pp. 847-854
-
-
Tanaka, K.1
Masu, M.2
Nakanishi, S.3
-
6
-
-
0030000931
-
Molecular cloning of a levocabastine-sensitive neurotensin binding site
-
Chalon P, et al. (1996) Molecular cloning of a levocabastine-sensitive neurotensin binding site. FEBS Lett 386(2-3):91-94.
-
(1996)
FEBS Lett
, vol.386
, Issue.2-3
, pp. 91-94
-
-
Chalon, P.1
-
7
-
-
0041341923
-
Differential involvement of intracellular domains of the rat NTS1 neurotensin receptor in coupling to G proteins: A molecular basis for agonist-directed trafficking of receptor stimulus
-
Skrzydelski D, et al. (2003) Differential involvement of intracellular domains of the rat NTS1 neurotensin receptor in coupling to G proteins: A molecular basis for agonist-directed trafficking of receptor stimulus. Mol Pharmacol 64(2): 421-429.
-
(2003)
Mol Pharmacol
, vol.64
, Issue.2
, pp. 421-429
-
-
Skrzydelski, D.1
-
8
-
-
33644614406
-
Cell-type-specific pathways of neurotensin endocytosis
-
Savdie C, Ferguson SS, Vincent J, Beaudet A, Stroh T (2006) Cell-type-specific pathways of neurotensin endocytosis. Cell Tissue Res 324(1):69-85.
-
(2006)
Cell Tissue Res
, vol.324
, Issue.1
, pp. 69-85
-
-
Savdie, C.1
Ferguson, S.S.2
Vincent, J.3
Beaudet, A.4
Stroh, T.5
-
9
-
-
0035101820
-
Evolving concepts in G protein-coupled receptor endocytosis: The role in receptor desensitization and signaling
-
Ferguson SS (2001) Evolving concepts in G protein-coupled receptor endocytosis: The role in receptor desensitization and signaling. Pharmacol Rev 53(1):1-24.
-
(2001)
Pharmacol Rev
, vol.53
, Issue.1
, pp. 1-24
-
-
Ferguson, S.S.1
-
10
-
-
1842330251
-
Neurotensin agonist induces differential regulation of neurotensin receptor mRNA. Identification of distinct transcriptional and post-transcriptional mechanisms
-
Souazé F, Rostène W, Forgez P (1997) Neurotensin agonist induces differential regulation of neurotensin receptor mRNA. Identification of distinct transcriptional and post-transcriptional mechanisms. J Biol Chem 272(15):10087-10094.
-
(1997)
J Biol Chem
, vol.272
, Issue.15
, pp. 10087-10094
-
-
Souazé, F.1
Rostène, W.2
Forgez, P.3
-
11
-
-
1842582007
-
Receptor trafficking via the perinuclear recycling compartment accompanied by cell division is necessary for permanent neurotensin cell sensitization and leads to chronic mitogenactivated protein kinase activation
-
Toy-Miou-Leong M, Cortes CL, Beaudet A, Rostène W, Forgez P (2004) Receptor trafficking via the perinuclear recycling compartment accompanied by cell division is necessary for permanent neurotensin cell sensitization and leads to chronic mitogenactivated protein kinase activation. J Biol Chem 279(13):12636-12646.
-
(2004)
J Biol Chem
, vol.279
, Issue.13
, pp. 12636-12646
-
-
Toy-Miou-Leong, M.1
Cortes, C.L.2
Beaudet, A.3
Rostène, W.4
Forgez, P.5
-
12
-
-
0343081370
-
X-Ray diffraction analysis of three-dimensional crystals of bovine rhodopsin obtained from mixed micelles
-
Okada T, et al. (2000) X-Ray diffraction analysis of three-dimensional crystals of bovine rhodopsin obtained from mixed micelles. J Struct Biol 130(1):73-80.
-
(2000)
J Struct Biol
, vol.130
, Issue.1
, pp. 73-80
-
-
Okada, T.1
-
13
-
-
79959564813
-
Agonist-bound adenosine A2A receptor structures reveal common features of GPCR activation
-
Lebon G, et al. (2011) Agonist-bound adenosine A2A receptor structures reveal common features of GPCR activation. Nature 474(7352):521-525.
-
(2011)
Nature
, vol.474
, Issue.7352
, pp. 521-525
-
-
Lebon, G.1
-
14
-
-
47949129742
-
Structure of a beta1-adrenergic G-protein-coupled receptor
-
Warne T, et al. (2008) Structure of a beta1-adrenergic G-protein-coupled receptor. Nature 454(7203):486-491.
-
(2008)
Nature
, vol.454
, Issue.7203
, pp. 486-491
-
-
Warne, T.1
-
15
-
-
54449087770
-
Directed evolution of a G protein-coupled receptor for expression, stability, and binding selectivity
-
Sarkar CA, et al. (2008) Directed evolution of a G protein-coupled receptor for expression, stability, and binding selectivity. Proc Natl Acad Sci USA 105(39):14808-14813.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, Issue.39
, pp. 14808-14813
-
-
Sarkar, C.A.1
-
16
-
-
84862546176
-
Critical features for biosynthesis, stability, and functionality of a G protein-coupled receptor uncovered by all-versus-all mutations
-
Schlinkmann KM, et al. (2012) Critical features for biosynthesis, stability, and functionality of a G protein-coupled receptor uncovered by all-versus-all mutations. Proc Natl Acad Sci USA 109(25):9810-9815.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, Issue.25
, pp. 9810-9815
-
-
Schlinkmann, K.M.1
-
17
-
-
84865068808
-
Maximizing detergent stability and functional expression of a GPCR by exhaustive recombination and evolution
-
Schlinkmann KM, et al. (2012) Maximizing detergent stability and functional expression of a GPCR by exhaustive recombination and evolution. J Mol Biol 422(3): 414-428.
-
(2012)
J Mol Biol
, vol.422
, Issue.3
, pp. 414-428
-
-
Schlinkmann, K.M.1
-
18
-
-
84872867691
-
Direct molecular evolution of detergent-stable G proteincoupled receptors using polymer encapsulated cells
-
Scott DJ, Plückthun A (2013) Direct molecular evolution of detergent-stable G proteincoupled receptors using polymer encapsulated cells. J Mol Biol 425(3):662-677.
-
(2013)
J Mol Biol
, vol.425
, Issue.3
, pp. 662-677
-
-
Scott, D.J.1
Plückthun, A.2
-
19
-
-
33748742717
-
Functional domains of the subtype 1 neurotensin receptor (NTS1)
-
Kitabgi P (2006) Functional domains of the subtype 1 neurotensin receptor (NTS1). Peptides 27(10):2461-2468.
-
(2006)
Peptides
, vol.27
, Issue.10
, pp. 2461-2468
-
-
Kitabgi, P.1
-
20
-
-
0026755609
-
Analysis and refinement of criteria for predicting the structure and relative orientations of transmembranal helical domains
-
Ballesteros JA, Weinstein H (1992) Analysis and refinement of criteria for predicting the structure and relative orientations of transmembranal helical domains. Biophys J 62(1):107-109.
-
(1992)
Biophys J
, vol.62
, Issue.1
, pp. 107-109
-
-
Ballesteros, J.A.1
Weinstein, H.2
-
21
-
-
79955021788
-
Evolution of three human GPCRs for higher expression and stability
-
Dodevski I, Plückthun A (2011) Evolution of three human GPCRs for higher expression and stability. J Mol Biol 408(4):599-615.
-
(2011)
J Mol Biol
, vol.408
, Issue.4
, pp. 599-615
-
-
Dodevski, I.1
Plückthun, A.2
-
22
-
-
79953234218
-
Crystal structure of metarhodopsin II
-
Choe HW, et al. (2011) Crystal structure of metarhodopsin II. Nature 471(7340): 651-655.
-
(2011)
Nature
, vol.471
, Issue.7340
, pp. 651-655
-
-
Choe, H.W.1
-
23
-
-
80051658642
-
Crystal structure of the β2 adrenergic receptor-Gs protein complex
-
Rasmussen SG, et al. (2011) Crystal structure of the β2 adrenergic receptor-Gs protein complex. Nature 477(7366):549-555.
-
(2011)
Nature
, vol.477
, Issue.7366
, pp. 549-555
-
-
Rasmussen, S.G.1
-
24
-
-
79953242234
-
The structural basis of agonist-induced activation in constitutively active rhodopsin
-
Standfuss J, et al. (2011) The structural basis of agonist-induced activation in constitutively active rhodopsin. Nature 471(7340):656-660.
-
(2011)
Nature
, vol.471
, Issue.7340
, pp. 656-660
-
-
Standfuss, J.1
-
25
-
-
52949102889
-
Crystal structure of opsin in its G-protein-interacting conformation
-
Scheerer P, et al. (2008) Crystal structure of opsin in its G-protein-interacting conformation. Nature 455(7212):497-502.
-
(2008)
Nature
, vol.455
, Issue.7212
, pp. 497-502
-
-
Scheerer, P.1
-
26
-
-
84867840947
-
Structure of the agonist-bound neurotensin receptor
-
White JF, et al. (2012) Structure of the agonist-bound neurotensin receptor. Nature 490(7421):508-513.
-
(2012)
Nature
, vol.490
, Issue.7421
, pp. 508-513
-
-
White, J.F.1
-
27
-
-
80052082999
-
Structural insights into agonist-induced activation of G-protein-coupled receptors
-
Deupi X, Standfuss J (2011) Structural insights into agonist-induced activation of G-protein-coupled receptors. Curr Opin Struct Biol 21(4):541-551.
-
(2011)
Curr Opin Struct Biol
, vol.21
, Issue.4
, pp. 541-551
-
-
Deupi, X.1
Standfuss, J.2
-
28
-
-
0030995335
-
Identification in the rat neurotensin receptor of amino-acid residues critical for the binding of neurotensin
-
Botto JM, et al. (1997) Identification in the rat neurotensin receptor of amino-acid residues critical for the binding of neurotensin. Brain Res Mol Brain Res 46(1-2):311-317.
-
(1997)
Brain Res Mol Brain Res
, vol.46
, Issue.1-2
, pp. 311-317
-
-
Botto, J.M.1
-
29
-
-
0034614509
-
Identification of residues involved in neurotensin binding and modeling of the agonist binding site in neurotensin receptor
-
Barroso S, et al. (2000) Identification of residues involved in neurotensin binding and modeling of the agonist binding site in neurotensin receptor. J Biol Chem 275(1): 328-336
-
(2000)
J Biol Chem
, vol.275
, Issue.1
, pp. 328-336
-
-
Barroso, S.1
-
30
-
-
62949153556
-
Role of helix 8 in G proteincoupled receptors based on structure-function studies on the type 1 angiotensin receptor
-
Huynh J, Thomas WG, Aguilar MI, Pattenden LK (2009) Role of helix 8 in G proteincoupled receptors based on structure-function studies on the type 1 angiotensin receptor. Mol Cell Endocrinol 302(2):118-127.
-
(2009)
Mol Cell Endocrinol
, vol.302
, Issue.2
, pp. 118-127
-
-
Huynh, J.1
Thomas, W.G.2
Aguilar, M.I.3
Pattenden, L.K.4
-
31
-
-
33744949264
-
Characterization of the residues in helix 8 of the human beta1-adrenergic receptor that are involved in coupling the receptor to G proteins
-
Delos Santos NM, Gardner LA, White SW, Bahouth SW (2006) Characterization of the residues in helix 8 of the human beta1-adrenergic receptor that are involved in coupling the receptor to G proteins. J Biol Chem 281(18):12896-12907.
-
(2006)
J Biol Chem
, vol.281
, Issue.18
, pp. 12896-12907
-
-
Delos Santos, N.M.1
Gardner, L.A.2
White, S.W.3
Bahouth, S.W.4
-
32
-
-
0042357127
-
Selective interactions between helix VIII of the human muopioid receptors and the C terminus of periplakin disrupt G protein activation
-
Feng GJ, et al. (2003) Selective interactions between helix VIII of the human muopioid receptors and the C terminus of periplakin disrupt G protein activation. J Biol Chem 278(35):33400-33407.
-
(2003)
J Biol Chem
, vol.278
, Issue.35
, pp. 33400-33407
-
-
Feng, G.J.1
-
33
-
-
1642267055
-
Residues in the hydrophilic face of putative helix 8 of oxytocin receptor are important for receptor function
-
Zhong M, Navratil AM, Clay C, Sanborn BM (2004) Residues in the hydrophilic face of putative helix 8 of oxytocin receptor are important for receptor function. Biochemistry 43(12):3490-3498.
-
(2004)
Biochemistry
, vol.43
, Issue.12
, pp. 3490-3498
-
-
Zhong, M.1
Navratil, A.M.2
Clay, C.3
Sanborn, B.M.4
-
34
-
-
81755187017
-
Conformational dynamics of helix 8 in the GPCR rhodopsin controls arrestin activation in the desensitization process
-
Kirchberg K, et al. (2011) Conformational dynamics of helix 8 in the GPCR rhodopsin controls arrestin activation in the desensitization process. Proc Natl Acad Sci USA 108(46):18690-18695.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, Issue.46
, pp. 18690-18695
-
-
Kirchberg, K.1
-
35
-
-
34248525279
-
Crystal packing analysis of Rhodopsin crystals
-
Lodowski DT, et al. (2007) Crystal packing analysis of Rhodopsin crystals. J Struct Biol 158(3):455-462.
-
(2007)
J Struct Biol
, vol.158
, Issue.3
, pp. 455-462
-
-
Lodowski, D.T.1
-
36
-
-
11444257315
-
The role of helix 8 and of the cytosolic C-termini in the internalization and signal transduction of B(1) and B(2) bradykinin receptors
-
Faussner A, et al. (2005) The role of helix 8 and of the cytosolic C-termini in the internalization and signal transduction of B(1) and B(2) bradykinin receptors. FEBS J 272(1):129-140.
-
(2005)
FEBS J
, vol.272
, Issue.1
, pp. 129-140
-
-
Faussner, A.1
-
37
-
-
0027772959
-
Shape complementarity at protein/protein interfaces
-
Lawrence MC, Colman PM (1993) Shape complementarity at protein/protein interfaces. J Mol Biol 234(4):946-950.
-
(1993)
J Mol Biol
, vol.234
, Issue.4
, pp. 946-950
-
-
Lawrence, M.C.1
Colman, P.M.2
-
38
-
-
85027927015
-
Structures of the CXCR4 chemokine GPCR with small-molecule and cyclic peptide antagonists
-
Wu B, et al. (2010) Structures of the CXCR4 chemokine GPCR with small-molecule and cyclic peptide antagonists. Science 330(6007):1066-1071.
-
(2010)
Science
, vol.330
, Issue.6007
, pp. 1066-1071
-
-
Wu, B.1
-
39
-
-
84871411930
-
High-resolution crystal structure of human protease-activated receptor
-
Zhang C, et al. (2012) High-resolution crystal structure of human protease-activated receptor. Nature 492(7429):387-392
-
(2012)
Nature
, vol.492
, Issue.7429
, pp. 387-392
-
-
Zhang, C.1
-
40
-
-
81755166179
-
Activation and molecular recognition of the GPCR rhodopsin-Insights from time-resolved fluorescence depolarisation and single molecule experiments
-
Kim TY, Schlieter T, Haase S, Alexiev U (2012) Activation and molecular recognition of the GPCR rhodopsin-Insights from time-resolved fluorescence depolarisation and single molecule experiments. Eur J Cell Biol 91(4):300-310.
-
(2012)
Eur J Cell Biol
, vol.91
, Issue.4
, pp. 300-310
-
-
Kim, T.Y.1
Schlieter, T.2
Haase, S.3
Alexiev, U.4
-
41
-
-
84864751433
-
Membrane-sensitive conformational states of helix 8 in the metabotropic Glu2 receptor, a class C GPCR
-
Bruno A, Costantino G, de Fabritiis G, Pastor M, Selent J (2012) Membrane-sensitive conformational states of helix 8 in the metabotropic Glu2 receptor, a class C GPCR. PLoS ONE 7(8):e42023.
-
(2012)
PLoS ONE
, vol.7
, Issue.8
-
-
Bruno, A.1
Costantino, G.2
De Fabritiis, G.3
Pastor, M.4
Selent, J.5
-
42
-
-
47049130668
-
Crystal structure of the ligand-free G-protein-coupled receptor opsin
-
Park JH, Scheerer P, Hofmann KP, Choe HW, Ernst OP (2008) Crystal structure of the ligand-free G-protein-coupled receptor opsin. Nature 454(7201):183-187.
-
(2008)
Nature
, vol.454
, Issue.7201
, pp. 183-187
-
-
Park, J.H.1
Scheerer, P.2
Hofmann, K.P.3
Choe, H.W.4
Ernst, O.P.5
-
43
-
-
0026543668
-
Mitosis and inhibition of intracellular transport stimulate palmitoylation of a 62-kD protein
-
Mundy DI, Warren G (1992) Mitosis and inhibition of intracellular transport stimulate palmitoylation of a 62-kD protein. J Cell Biol 116(1):135-146.
-
(1992)
J Cell Biol
, vol.116
, Issue.1
, pp. 135-146
-
-
Mundy, D.I.1
Warren, G.2
-
44
-
-
0038757730
-
Role of palmitoylation/depalmitoylation reactions in G-protein-coupled receptor function
-
Qanbar R, Bouvier M (2003) Role of palmitoylation/depalmitoylation reactions in G-protein-coupled receptor function. Pharmacol Ther 97(1):1-33.
-
(2003)
Pharmacol Ther
, vol.97
, Issue.1
, pp. 1-33
-
-
Qanbar, R.1
Bouvier, M.2
-
45
-
-
67649306770
-
G-protein-coupled receptors, cholesterol and palmitoylation: Facts about fats
-
Chini B, Parenti M (2009) G-protein-coupled receptors, cholesterol and palmitoylation: Facts about fats. J Mol Endocrinol 42(5):371-379.
-
(2009)
J Mol Endocrinol
, vol.42
, Issue.5
, pp. 371-379
-
-
Chini, B.1
Parenti, M.2
-
46
-
-
0029838532
-
Purification of a rat neurotensin receptor expressed in Escherichia coli
-
Tucker J, Grisshammer R (1996) Purification of a rat neurotensin receptor expressed in Escherichia coli. Biochem J 317(Pt 3):891-899.
-
(1996)
Biochem J
, vol.317
, Issue.PART 3
, pp. 891-899
-
-
Tucker, J.1
Grisshammer, R.2
-
47
-
-
1942468187
-
Automated large-scale purification of a G protein-coupled receptor for neurotensin
-
White JF, Trinh LB, Shiloach J, Grisshammer R (2004) Automated large-scale purification of a G protein-coupled receptor for neurotensin. FEBS Lett 564(3):289-293.
-
(2004)
FEBS Lett
, vol.564
, Issue.3
, pp. 289-293
-
-
White, J.F.1
Trinh, L.B.2
Shiloach, J.3
Grisshammer, R.4
-
48
-
-
26444581283
-
Large-scale expression and purification of a G-protein-coupled receptor for structure determination-An overview
-
Grisshammer R, White JF, Trinh LB, Shiloach J (2005) Large-scale expression and purification of a G-protein-coupled receptor for structure determination-An overview. J Struct Funct Genomics 6(2-3):159-163.
-
(2005)
J Struct Funct Genomics
, vol.6
, Issue.2-3
, pp. 159-163
-
-
Grisshammer, R.1
White, J.F.2
Trinh, L.B.3
Shiloach, J.4
-
49
-
-
80052372651
-
Neurotensin receptor-1 inducible palmitoylation is required for efficient receptor-mediated mitogenic-signaling within structured membrane microdomains
-
Heakal Y, et al. (2011) Neurotensin receptor-1 inducible palmitoylation is required for efficient receptor-mediated mitogenic-signaling within structured membrane microdomains. Cancer Biol Ther 12(5):427-435.
-
(2011)
Cancer Biol Ther
, vol.12
, Issue.5
, pp. 427-435
-
-
Heakal, Y.1
|