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Volumn 20, Issue 17, 2012, Pages 5254-5261
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Virtual screening leads to the discovery of novel non-nucleotide P2Y 1 receptor antagonists
a,d
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Author keywords
Antagonist; G protein coupled receptor; Molecular modeling; P2Y1 receptor; Virtual screening
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Indexed keywords
4 [3 (3 CHLORO 4 FLUOROPHENYL)UREIDO] N (3,4 DIMETHYLISOXAZOL)BENZESULFONAMIDE;
4 [3 (3 CHLOROPHENYL)UREIDO] N (3,4 DIMETHYLISOXAZOL)BENZESULFONAMIDE;
4 [3 (3,4 DICHLOROPHENYL)UREIDO] N (3,4 DIMETHYLISOXAZOL 5 YL)BENZESULFONAMIDE;
4 [3 (3,4 DIFLUOROPHENYL)UREIDO] N (3,4 DIMETHYLISOXAZOL)BENZESULFONAMIDE;
4 [3 (3,5 DICHLOROPHENYL)UREIDO] N (3,4 DIMETHYLISOXAZOL)BENZESULFONAMIDE;
4 [3 (3,5 DIFLUOROPHENYL)UREIDO] N (3,4 DIMETHYLISOXAZOL)BENZESULFONAMIDE;
4 AMINO N (3,4 DIMETHYLISOXAZOL 5 YL)BENZESULFONAMIDE;
N (3,4 DIMETHYLISOXAZOL 5 YL) 4 (3 PHENYLUREIDO)BENZESULFONAMIDE;
N (3,4 DIMETHYLISOXAZOL 5 YL) 4 [3 (3,4 DIMETHYLPHENYL)UREIDO]BENZESULFONAMIDE;
N (3,4 DIMETHYLISOXAZOL 5 YL) 4 [3 [4 (TRIFLUOROMETHYL)PHENYL]UREIDO] BENZESULFONAMIDE;
N (3,4 DIMETHYLISOXAZOL 5 YL) 4 NITROBENZESULFONAMIDE;
PURINERGIC P2Y RECEPTOR ANTAGONIST;
UNCLASSIFIED DRUG;
ANIMAL CELL;
ARTICLE;
BINDING AFFINITY;
CONCENTRATION RESPONSE;
DRUG RECEPTOR BINDING;
DRUG SCREENING;
DRUG STRUCTURE;
DRUG SYNTHESIS;
HUMAN;
HUMAN CELL;
HYDROGEN BOND;
MOLECULAR DOCKING;
NONHUMAN;
PHARMACOPHORE;
PHYSICAL CHEMISTRY;
RADIOASSAY;
STRUCTURE ACTIVITY RELATION;
VIRTUAL REALITY;
DOSE-RESPONSE RELATIONSHIP, DRUG;
DRUG DISCOVERY;
HUMANS;
MODELS, MOLECULAR;
MOLECULAR STRUCTURE;
RECEPTORS, PURINERGIC P2Y1;
STRUCTURE-ACTIVITY RELATIONSHIP;
SULFONAMIDES;
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EID: 84864968174
PISSN: 09680896
EISSN: 14643391
Source Type: Journal
DOI: 10.1016/j.bmc.2012.06.044 Document Type: Article |
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Times cited : (21)
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References (20)
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