-
1
-
-
33748455338
-
Type I interferons in host defense
-
D. B. Stetson, R. Medzhitov, Type I interferons in host defense. Immunity 25, 373-381 (2006).
-
(2006)
Immunity
, vol.25
, pp. 373-381
-
-
Stetson, D.B.1
Medzhitov, R.2
-
2
-
-
33744791510
-
Essential role of mda-5 in type I IFN responses to polyriboinosinic: Polyribocytidylic acid and encephalomyocarditis picornavirus
-
L. Gitlin, W. Barchet, S. Gilfillan, M. Cella, B. Beutler, R. A. Flavell, M. S. Diamond, M. Colonna, Essential role of mda-5 in type I IFN responses to polyriboinosinic: polyribocytidylic acid and encephalomyocarditis picornavirus. Proc. Natl. Acad. Sci. U.S.A. 103, 8459-8464 (2006).
-
(2006)
Proc. Natl. Acad. Sci. U.S.A.
, vol.103
, pp. 8459-8464
-
-
Gitlin, L.1
Barchet, W.2
Gilfillan, S.3
Cella, M.4
Beutler, B.5
Flavell, R.A.6
Diamond, M.S.7
Colonna, M.8
-
3
-
-
3242813113
-
The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses
-
M. Yoneyama, M. Kikuchi, T. Natsukawa, N. Shinobu, T. Imaizumi, M. Miyagishi, K. Taira, S. Akira, T. Fujita, The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses. Nat. Immunol. 5, 730-737 (2004).
-
(2004)
Nat. Immunol.
, vol.5
, pp. 730-737
-
-
Yoneyama, M.1
Kikuchi, M.2
Natsukawa, T.3
Shinobu, N.4
Imaizumi, T.5
Miyagishi, M.6
Taira, K.7
Akira, S.8
Fujita, T.9
-
4
-
-
27144440523
-
IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction
-
T. Kawai, K. Takahashi, S. Sato, C. Coban, H. Kumar, H. Kato, K. J. Ishii, O. Takeuchi, S. Akira, IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction. Nat. Immunol. 6, 981-988 (2005).
-
(2005)
Nat. Immunol.
, vol.6
, pp. 981-988
-
-
Kawai, T.1
Takahashi, K.2
Sato, S.3
Coban, C.4
Kumar, H.5
Kato, H.6
Ishii, K.J.7
Takeuchi, O.8
Akira, S.9
-
5
-
-
24144461689
-
Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-kB and IRF 3
-
R. B. Seth, L. Sun, C. K. Ea, Z. J. Chen, Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-kB and IRF 3. Cell 122, 669-682 (2005).
-
(2005)
Cell
, vol.122
, pp. 669-682
-
-
Seth, R.B.1
Sun, L.2
Ea, C.K.3
Chen, Z.J.4
-
6
-
-
27144440476
-
Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus
-
E. Meylan, J. Curran, K. Hofmann, D. Moradpour, M. Binder, R. Bartenschlager, J. Tschopp, Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus. Nature 437, 1167-1172 (2005).
-
(2005)
Nature
, vol.437
, pp. 1167-1172
-
-
Meylan, E.1
Curran, J.2
Hofmann, K.3
Moradpour, D.4
Binder, M.5
Bartenschlager, R.6
Tschopp, J.7
-
7
-
-
24944538819
-
VISA is an adapter protein required for virus-triggered IFN-b signaling
-
L. G. Xu, Y. Y. Wang, K. J. Han, L. Y. Li, Z. Zhai, H. B. Shu, VISA is an adapter protein required for virus-triggered IFN-b signaling. Mol. Cell 19, 727-740 (2005).
-
(2005)
Mol. Cell
, vol.19
, pp. 727-740
-
-
Xu, L.G.1
Wang, Y.Y.2
Han, K.J.3
Li, L.Y.4
Zhai, Z.5
Shu, H.B.6
-
8
-
-
33746479050
-
Regulation of antiviral responses by a direct and specific interaction between TRAF3 and Cardif
-
S. K. Saha, E. M. Pietras, J. Q. He, J. R. Kang, S. Y. Liu, G. Oganesyan, A. Shahangian, B. Zarnegar, T. L. Shiba, Y. Wang, G. Cheng, Regulation of antiviral responses by a direct and specific interaction between TRAF3 and Cardif. EMBO J. 25, 3257-3263 (2006).
-
(2006)
EMBO J.
, vol.25
, pp. 3257-3263
-
-
Saha, S.K.1
Pietras, E.M.2
He, J.Q.3
Kang, J.R.4
Liu, S.Y.5
Oganesyan, G.6
Shahangian, A.7
Zarnegar, B.8
Shiba, T.L.9
Wang, Y.10
Cheng, G.11
-
9
-
-
77949427242
-
TRAF5 is a downstream target of MAVS in antiviral innate immune signaling
-
E. D. Tang, C. Y. Wang, TRAF5 is a downstream target of MAVS in antiviral innate immune signaling. PLOS One 5, e9172 (2010).
-
(2010)
PLOS One
, vol.5
-
-
Tang, E.D.1
Wang, C.Y.2
-
10
-
-
0033257795
-
JNK2 and IKKb are required for activating the innate response to viral infection
-
W. M. Chu, D. Ostertag, Z. W. Li, L. Chang, Y. Chen, Y. Hu, B. Williams, J. Perrault, M. Karin, JNK2 and IKKb are required for activating the innate response to viral infection. Immunity 11, 721-731 (1999).
-
(1999)
Immunity
, vol.11
, pp. 721-731
-
-
Chu, W.M.1
Ostertag, D.2
Li, Z.W.3
Chang, L.4
Chen, Y.5
Hu, Y.6
Williams, B.7
Perrault, J.8
Karin, M.9
-
11
-
-
0026604277
-
An ATF/CREB binding site is required for virus induction of the human interferon b gene
-
W. Du, T. Maniatis, An ATF/CREB binding site is required for virus induction of the human interferon b gene. Proc. Natl. Acad. Sci. U.S.A. 89, 2150-2154 (1992).
-
(1992)
Proc. Natl. Acad. Sci. U.S.A.
, vol.89
, pp. 2150-2154
-
-
Du, W.1
Maniatis, T.2
-
12
-
-
0022372055
-
Delimitation and properties of DNA sequence: Required for the regulated expression of human interferon-b gene
-
T. Fujita, S. Ohno, H. Yasumitsu, T. Taniguchi, Delimitation and properties of DNA sequence: Required for the regulated expression of human interferon-b gene. Cell 41, 489-496 (1985).
-
(1985)
Cell
, vol.41
, pp. 489-496
-
-
Fujita, T.1
Ohno, S.2
Yasumitsu, H.3
Taniguchi, T.4
-
13
-
-
61349146561
-
TRAF6 and MEKK1 play a pivotal role in the RIG-I-like helicase antiviral pathway
-
R. Yoshida, G. Takaesu, H. Yoshida, F. Okamoto, T. Yoshioka, Y. Choi, S. Akira, T. Kawai, A. Yoshimura, T. Kobayashi, TRAF6 and MEKK1 play a pivotal role in the RIG-I-like helicase antiviral pathway. J. Biol. Chem. 283, 36211-36220 (2008).
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 36211-36220
-
-
Yoshida, R.1
Takaesu, G.2
Yoshida, H.3
Okamoto, F.4
Yoshioka, T.5
Choi, Y.6
Akira, S.7
Kawai, T.8
Yoshimura, A.9
Kobayashi, T.10
-
14
-
-
0027215907
-
Apoptosis reduces both the in vitro replication and the in vivo infectivity of a baculovirus
-
R. J. Clem, L. K. Miller, Apoptosis reduces both the in vitro replication and the in vivo infectivity of a baculovirus. J. Virol. 67, 3730-3738 (1993).
-
(1993)
J. Virol.
, vol.67
, pp. 3730-3738
-
-
Clem, R.J.1
Miller, L.K.2
-
15
-
-
0031937494
-
The fight of viruses against apoptosis
-
J. Tschopp, M. Thome, K. Hofmann, E. Meinl, The fight of viruses against apoptosis. Curr. Opin. Genet. Dev. 8, 82-87 (1998).
-
(1998)
Curr. Opin. Genet. Dev.
, vol.8
, pp. 82-87
-
-
Tschopp, J.1
Thome, M.2
Hofmann, K.3
Meinl, E.4
-
16
-
-
79952857824
-
The IRF-3/Bax-mediated apoptotic pathway, activated by viral cytoplasmic RNA and DNA, inhibits virus replication
-
S. Chattopadhyay, M. Yamashita, Y. Zhang, G. C. Sen, The IRF-3/Bax-mediated apoptotic pathway, activated by viral cytoplasmic RNA and DNA, inhibits virus replication. J. Virol. 85, 3708-3716 (2011).
-
(2011)
J. Virol.
, vol.85
, pp. 3708-3716
-
-
Chattopadhyay, S.1
Yamashita, M.2
Zhang, Y.3
Sen, G.C.4
-
17
-
-
40749162423
-
Cytosolic antiviral RNA recognition pathway activates caspases 1 and 3
-
J. Rintahaka, D. Wiik, P. E. Kovanen, H. Alenius, S. Matikainen, Cytosolic antiviral RNA recognition pathway activates caspases 1 and 3. J. Immunol. 180, 1749-1757 (2008).
-
(2008)
J. Immunol.
, vol.180
, pp. 1749-1757
-
-
Rintahaka, J.1
Wiik, D.2
Kovanen, P.E.3
Alenius, H.4
Matikainen, S.5
-
18
-
-
68849096790
-
Proapoptotic signaling induced by RIG-I and MDA-5 results in type I interferon-independent apoptosis in human melanoma cells
-
R. Besch, H. Poeck, T. Hohenauer, D. Senft, G. Häcker, C. Berking, V. Hornung, S. Endres, T. Ruzicka, S. Rothenfusser, G. Hartmann, Proapoptotic signaling induced by RIG-I and MDA-5 results in type I interferon-independent apoptosis in human melanoma cells. J. Clin. Invest. 119, 2399-2411 (2009).
-
(2009)
J. Clin. Invest.
, vol.119
, pp. 2399-2411
-
-
Besch, R.1
Poeck, H.2
Hohenauer, T.3
Senft, D.4
Häcker, G.5
Berking, C.6
Hornung, V.7
Endres, S.8
Ruzicka, T.9
Rothenfusser, S.10
Hartmann, G.11
-
19
-
-
84875981860
-
MAVS-mediated apoptosis and its inhibition by viral proteins
-
Y. Lei, C. B. Moore, R. M. Liesman, B. P. O'Connor, D. T. Bergstralh, Z. J. Chen, R. J. Pickles, J. P. Ting, MAVS-mediated apoptosis and its inhibition by viral proteins. PLOS One 4, e5466 (2009).
-
(2009)
PLOS One
, vol.4
-
-
Lei, Y.1
Moore, C.B.2
Liesman, R.M.3
O'Connor, B.P.4
Bergstralh, D.T.5
Chen, Z.J.6
Pickles, R.J.7
Ting, J.P.8
-
20
-
-
0041662272
-
Integration of interferon-a/b signalling to p53 responses in tumour suppression and antiviral defence
-
A.Takaoka,S.Hayakawa,H.Yanai,D.Stoiber,H.Negishi,H.Kikuchi,S.Sasaki, K. Imai, T. Shibue, K. Honda, T. Taniguchi, Integration of interferon-a/b signalling to p53 responses in tumour suppression and antiviral defence. Nature 424, 516-523 (2003).
-
(2003)
Nature
, vol.424
, pp. 516-523
-
-
Takaoka, A.1
Hayakawa, S.2
Yanai, H.3
Stoiber, D.4
Negishi, H.5
Kikuchi, H.6
Sasaki, S.7
Imai, K.8
Shibue, T.9
Honda, K.10
Taniguchi, T.11
-
21
-
-
23844488691
-
Down-regulation of p53 by double-stranded RNA modulates the antiviral response
-
J. T. Marques, D. Rebouillat, C. V. Ramana, J. Murakami, J. E. Hill, A. Gudkov, R. H. Silverman, G. R. Stark, B. R. Williams, Down-regulation of p53 by double-stranded RNA modulates the antiviral response. J. Virol. 79, 11105-11114 (2005).
-
(2005)
J. Virol.
, vol.79
, pp. 11105-11114
-
-
Marques, J.T.1
Rebouillat, D.2
Ramana, C.V.3
Murakami, J.4
Hill, J.E.5
Gudkov, A.6
Silverman, R.H.7
Stark, G.R.8
Williams, B.R.9
-
22
-
-
0035128587
-
Apoptosis is promoted by the dsRNA-activated factor (DRAF1) during viral infection independent of the action of interferon or p53
-
B. K. Weaver, O. Ando, K. P. Kumar, N. C. Reich, Apoptosis is promoted by the dsRNA-activated factor (DRAF1) during viral infection independent of the action of interferon or p53. FASEB J. 15, 501-515 (2001).
-
(2001)
FASEB J.
, vol.15
, pp. 501-515
-
-
Weaver, B.K.1
Ando, O.2
Kumar, K.P.3
Reich, N.C.4
-
23
-
-
77952578865
-
Viral apoptosis is induced by IRF-3-mediated activation of Bax
-
S. Chattopadhyay, J. T. Marques, M. Yamashita, K. L. Peters, K. Smith, A. Desai, B. R. Williams, G. C. Sen, Viral apoptosis is induced by IRF-3-mediated activation of Bax. EMBO J. 29, 1762-1773 (2010).
-
(2010)
EMBO J.
, vol.29
, pp. 1762-1773
-
-
Chattopadhyay, S.1
Marques, J.T.2
Yamashita, M.3
Peters, K.L.4
Smith, K.5
Desai, A.6
Williams, B.R.7
Sen, G.C.8
-
24
-
-
84919884654
-
Apoptotic caspases suppress mtDNA-induced STING-mediated type I IFN production
-
M. J. White, K. McArthur, D. Metcalf, R. M. Lane, J. C. Cambier, M. J. Herold, M. F. van Delft, S. Bedoui, G. Lessene, M. E. Ritchie, D. C. Huang, B. T. Kile, Apoptotic caspases suppress mtDNA-induced STING-mediated type I IFN production. Cell 159, 1549-1562 (2014).
-
(2014)
Cell
, vol.159
, pp. 1549-1562
-
-
White, M.J.1
McArthur, K.2
Metcalf, D.3
Lane, R.M.4
Cambier, J.C.5
Herold, M.J.6
Van Delft, M.F.7
Bedoui, S.8
Lessene, G.9
Ritchie, M.E.10
Huang, D.C.11
Kile, B.T.12
-
25
-
-
4344627833
-
Type I interferon production enhances susceptibility to Listeria monocytogenes infection
-
R. M. O'Connell, S. K. Saha, S. A. Vaidya, K. W. Bruhn, G. A. Miranda, B. Zarnegar, A. K. Perry, B. O. Nguyen, T. F. Lane, T. Taniguchi, J. F. Miller, G. Cheng, Type I interferon production enhances susceptibility to Listeria monocytogenes infection. J. Exp. Med. 200, 437-445 (2004).
-
(2004)
J. Exp. Med.
, vol.200
, pp. 437-445
-
-
O'Connell, R.M.1
Saha, S.K.2
Vaidya, S.A.3
Bruhn, K.W.4
Miranda, G.A.5
Zarnegar, B.6
Perry, A.K.7
Nguyen, B.O.8
Lane, T.F.9
Taniguchi, T.10
Miller, J.F.11
Cheng, G.12
-
26
-
-
79951740151
-
Type I interferon inhibits interleukin-1 production and inflammasome activation
-
G. Guarda, M. Braun, F. Staehli, A. Tardivel, C. Mattmann, I. Förster, M. Farlik, T. Decker, R. A. Du Pasquier, P. Romero, J. Tschopp, Type I interferon inhibits interleukin-1 production and inflammasome activation. Immunity 34, 213-223 (2011).
-
(2011)
Immunity
, vol.34
, pp. 213-223
-
-
Guarda, G.1
Braun, M.2
Staehli, F.3
Tardivel, A.4
Mattmann, C.5
Förster, I.6
Farlik, M.7
Decker, T.8
Du Pasquier, R.A.9
Romero, P.10
Tschopp, J.11
-
27
-
-
79958746242
-
Viral infection augments Nod1/2 signaling to potentiate lethality associated with secondary bacterial infections
-
Y. G. Kim, J. H. Park, T. Reimer, D. P. Baker, T. Kawai, H. Kumar, S. Akira, C. Wobus, G. Núñez, Viral infection augments Nod1/2 signaling to potentiate lethality associated with secondary bacterial infections. Cell Host Microbe 9, 496-507 (2011).
-
(2011)
Cell Host Microbe
, vol.9
, pp. 496-507
-
-
Kim, Y.G.1
Park, J.H.2
Reimer, T.3
Baker, D.P.4
Kawai, T.5
Kumar, H.6
Akira, S.7
Wobus, C.8
Núñez, G.9
-
28
-
-
84875425732
-
Type I interferon suppresses type II interferon-triggered human anti-mycobacterial responses
-
R. M. Teles, T. G. Graeber, S. R. Krutzik, D. Montoya, M. Schenk, D. J. Lee, E. Komisopoulou, K. Kelly-Scumpia, R. Chun, S. S. Iyer, E. N. Sarno, T. H. Rea, M. Hewison, J. S. Adams, S. J. Popper, D. A. Relman, S. Stenger, B. R. Bloom, G. Cheng, R. L. Modlin, Type I interferon suppresses type II interferon-triggered human anti-mycobacterial responses. Science 339, 1448-1453 (2013).
-
(2013)
Science
, vol.339
, pp. 1448-1453
-
-
Teles, R.M.1
Graeber, T.G.2
Krutzik, S.R.3
Montoya, D.4
Schenk, M.5
Lee, D.J.6
Komisopoulou, E.7
Kelly-Scumpia, K.8
Chun, R.9
Iyer, S.S.10
Sarno, E.N.11
Rea, T.H.12
Hewison, M.13
Adams, J.S.14
Popper, S.J.15
Relman, D.A.16
Stenger, S.17
Bloom, B.R.18
Cheng, G.19
Modlin, R.L.20
more..
-
29
-
-
0035066383
-
Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation
-
J. M. Kyriakis, J. Avruch, Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation. Physiol. Rev. 81, 807-869 (2001).
-
(2001)
Physiol. Rev.
, vol.81
, pp. 807-869
-
-
Kyriakis, J.M.1
Avruch, J.2
-
30
-
-
14444281569
-
Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways
-
H. Ichijo, E. Nishida, K. Irie, P. ten Dijke, M. Saitoh, T. Moriguchi, M. Takagi, K. Matsumoto, K. Miyazono, Y. Gotoh, Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways. Science 275, 90-94 (1997).
-
(1997)
Science
, vol.275
, pp. 90-94
-
-
Ichijo, H.1
Nishida, E.2
Irie, K.3
Ten Dijke, P.4
Saitoh, M.5
Moriguchi, T.6
Takagi, M.7
Matsumoto, K.8
Miyazono, K.9
Gotoh, Y.10
-
31
-
-
41149097725
-
Apoptosis signal-regulating kinase 1 in stress and immune response
-
K. Takeda, T. Noguchi, I. Naguro, H. Ichijo, Apoptosis signal-regulating kinase 1 in stress and immune response. Annu. Rev. Pharmacol. Toxicol. 48, 199-225 (2008).
-
(2008)
Annu. Rev. Pharmacol. Toxicol.
, vol.48
, pp. 199-225
-
-
Takeda, K.1
Noguchi, T.2
Naguro, I.3
Ichijo, H.4
-
32
-
-
27744559915
-
Recruitment of tumor necrosis factor receptor-associated factor family proteins to apoptosis signal-regulating kinase 1 signalosome is essential for oxidative stress-induced cell death
-
T. Noguchi, K. Takeda, A. Matsuzawa, K. Saegusa, H. Nakano, J. Gohda, J. Inoue, H. Ichijo, Recruitment of tumor necrosis factor receptor-associated factor family proteins to apoptosis signal-regulating kinase 1 signalosome is essential for oxidative stress-induced cell death. J. Biol. Chem. 280, 37033-37040 (2005).
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 37033-37040
-
-
Noguchi, T.1
Takeda, K.2
Matsuzawa, A.3
Saegusa, K.4
Nakano, H.5
Gohda, J.6
Inoue, J.7
Ichijo, H.8
-
33
-
-
34147186130
-
Apoptosis signal-regulating kinase (ASK) 2 functions as a mitogen-activated protein kinase kinase kinase in a heteromeric complex with ASK1
-
K. Takeda, R. Shimozono, T. Noguchi, T. Umeda, Y. Morimoto, I. Naguro, K. Tobiume, M. Saitoh, A. Matsuzawa, H. Ichijo, Apoptosis signal-regulating kinase (ASK) 2 functions as a mitogen-activated protein kinase kinase kinase in a heteromeric complex with ASK1. J. Biol. Chem. 282, 7522-7531 (2007).
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 7522-7531
-
-
Takeda, K.1
Shimozono, R.2
Noguchi, T.3
Umeda, T.4
Morimoto, Y.5
Naguro, I.6
Tobiume, K.7
Saitoh, M.8
Matsuzawa, A.9
Ichijo, H.10
-
34
-
-
65449146296
-
ASK1 and ASK2 differentially regulate the counteracting roles of apoptosis and inflammation in tumorigenesis
-
T. Iriyama, K. Takeda, H. Nakamura, Y. Morimoto, T. Kuroiwa, J. Mizukami, T. Umeda, T. Noguchi, I. Naguro, H. Nishitoh, K. Saegusa, K. Tobiume, T. Homma, Y. Shimada, H. Tsuda, S. Aiko, I. Imoto, J. Inazawa, K. Chida, Y. Kamei, S. Kozuma, Y. Taketani, A. Matsuzawa, H. Ichijo, ASK1 and ASK2 differentially regulate the counteracting roles of apoptosis and inflammation in tumorigenesis. EMBO J. 28, 843-853 (2009).
-
(2009)
EMBO J.
, vol.28
, pp. 843-853
-
-
Iriyama, T.1
Takeda, K.2
Nakamura, H.3
Morimoto, Y.4
Kuroiwa, T.5
Mizukami, J.6
Umeda, T.7
Noguchi, T.8
Naguro, I.9
Nishitoh, H.10
Saegusa, K.11
Tobiume, K.12
Homma, T.13
Shimada, Y.14
Tsuda, H.15
Aiko, S.16
Imoto, I.17
Inazawa, J.18
Chida, K.19
Kamei, Y.20
Kozuma, S.21
Taketani, Y.22
Matsuzawa, A.23
Ichijo, H.24
more..
-
35
-
-
0037178731
-
A conserved p38 MAP kinase pathway in Caenorhabditis elegans innate immunity
-
D. H. Kim, R. Feinbaum, G. Alloing, F. E. Emerson, D. A. Garsin, H. Inoue, M. Tanaka-Hino, N. Hisamoto, K. Matsumoto, M. W. Tan, F. M. Ausubel, A conserved p38 MAP kinase pathway in Caenorhabditis elegans innate immunity. Science 297, 623-626 (2002).
-
(2002)
Science
, vol.297
, pp. 623-626
-
-
Kim, D.H.1
Feinbaum, R.2
Alloing, G.3
Emerson, F.E.4
Garsin, D.A.5
Inoue, H.6
Tanaka-Hino, M.7
Hisamoto, N.8
Matsumoto, K.9
Tan, M.W.10
Ausubel, F.M.11
-
36
-
-
20644433073
-
ROS-dependent activation of the TRAF6-ASK1-p38 pathway is selectively required for TLR4-mediated innate immunity
-
A. Matsuzawa, K. Saegusa, T. Noguchi, C. Sadamitsu, H. Nishitoh, S. Nagai, S. Koyasu, K. Matsumoto, K. Takeda, H. Ichijo, ROS-dependent activation of the TRAF6-ASK1-p38 pathway is selectively required for TLR4-mediated innate immunity. Nat. Immunol. 6, 587-592 (2005).
-
(2005)
Nat. Immunol.
, vol.6
, pp. 587-592
-
-
Matsuzawa, A.1
Saegusa, K.2
Noguchi, T.3
Sadamitsu, C.4
Nishitoh, H.5
Nagai, S.6
Koyasu, S.7
Matsumoto, K.8
Takeda, K.9
Ichijo, H.10
-
37
-
-
33646342149
-
Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses
-
H. Kato, O. Takeuchi, S. Sato, M. Yoneyama, M. Yamamoto, K. Matsui, S. Uematsu, A. Jung, T. Kawai, K. J. Ishii, O. Yamaguchi, K. Otsu, T. Tsujimura, C. S. Koh, C. Reis e Sousa, Y. Matsuura, T. Fujita, S. Akira, Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses. Nature 441, 101-105 (2006).
-
(2006)
Nature
, vol.441
, pp. 101-105
-
-
Kato, H.1
Takeuchi, O.2
Sato, S.3
Yoneyama, M.4
Yamamoto, M.5
Matsui, K.6
Uematsu, S.7
Jung, A.8
Kawai, T.9
Ishii, K.J.10
Yamaguchi, O.11
Otsu, K.12
Tsujimura, T.13
Koh, C.S.14
Reis E Sousa, C.15
Matsuura, Y.16
Fujita, T.17
Akira, S.18
-
38
-
-
0035444539
-
Signal transduction by tumor necrosis factor and its relatives
-
V. Baud, M. Karin, Signal transduction by tumor necrosis factor and its relatives. Trends. Cell Biol. 11, 372-377 (2001).
-
(2001)
Trends. Cell Biol.
, vol.11
, pp. 372-377
-
-
Baud, V.1
Karin, M.2
-
39
-
-
0032158987
-
ASK1 is essential for JNK/SAPK activation by TRAF2
-
H. Nishitoh, M. Saitoh, Y. Mochida, K. Takeda, H. Nakano, M. Rothe, K. Miyazono, H. Ichijo, ASK1 is essential for JNK/SAPK activation by TRAF2. Mol. Cell 2, 389-395 (1998).
-
(1998)
Mol. Cell
, vol.2
, pp. 389-395
-
-
Nishitoh, H.1
Saitoh, M.2
Mochida, Y.3
Takeda, K.4
Nakano, H.5
Rothe, M.6
Miyazono, K.7
Ichijo, H.8
-
40
-
-
0036193169
-
Activation of apoptosis signal-regulating kinase 1 by the stress-induced activating phosphorylation of pre-formed oligomer
-
K. Tobiume, M. Saitoh, H. Ichijo, Activation of apoptosis signal-regulating kinase 1 by the stress-induced activating phosphorylation of pre-formed oligomer. J. Cell Physiol. 191, 95-104 (2002).
-
(2002)
J. Cell Physiol.
, vol.191
, pp. 95-104
-
-
Tobiume, K.1
Saitoh, M.2
Ichijo, H.3
-
41
-
-
0038105474
-
ASK1 regulates influenza virus infection-induced apoptotic cell death
-
S. Maruoka, S. Hashimoto, Y. Gon, H. Nishitoh, I. Takeshita, Y. Asai, K. Mizumura, K. Shimizu, H. Ichijo, T. Horie, ASK1 regulates influenza virus infection-induced apoptotic cell death. Biochem. Biophys. Res. Commun. 307, 870-876 (2003).
-
(2003)
Biochem. Biophys. Res. Commun.
, vol.307
, pp. 870-876
-
-
Maruoka, S.1
Hashimoto, S.2
Gon, Y.3
Nishitoh, H.4
Takeshita, I.5
Asai, Y.6
Mizumura, K.7
Shimizu, K.8
Ichijo, H.9
Horie, T.10
-
42
-
-
69149093400
-
In vitro and in vivo characterization of new swine-origin H1N1 influenza viruses
-
Y. Itoh, K. Shinya, M. Kiso, T. Watanabe, Y. Sakoda, M. Hatta, Y. Muramoto, D. Tamura, Y. Sakai-Tagawa, T. Noda, S. Sakabe, M. Imai, Y. Hatta, S. Watanabe, C. Li, S. Yamada, K. Fujii, S. Murakami, H. Imai, S. Kakugawa, M. Ito, R. Takano, K. Iwatsuki-Horimoto, M. Shimojima, T. Horimoto, H. Goto, K. Takahashi, A. Makino, H. Ishigaki, M. Nakayama, M. Okamatsu, D. Warshauer, P. A. Shult, R. Saito, H. Suzuki, Y. Furuta, M. Yamashita, K. Mitamura, K. Nakano, M. Nakamura, R. Brockman-Schneider, H. Mitamura, M. Yamazaki, N. Sugaya, M. Suresh, M. Ozawa, G. Neumann, J. Gern, H. Kida, K. Ogasawara, Y. Kawaoka, In vitro and in vivo characterization of new swine-origin H1N1 influenza viruses. Nature 460, 1021-1025 (2009).
-
(2009)
Nature
, vol.460
, pp. 1021-1025
-
-
Itoh, Y.1
Shinya, K.2
Kiso, M.3
Watanabe, T.4
Sakoda, Y.5
Hatta, M.6
Muramoto, Y.7
Tamura, D.8
Sakai-Tagawa, Y.9
Noda, T.10
Sakabe, S.11
Imai, M.12
Hatta, Y.13
Watanabe, S.14
Li, C.15
Yamada, S.16
Fujii, K.17
Murakami, S.18
Imai, H.19
Kakugawa, S.20
Ito, M.21
Takano, R.22
Iwatsuki-Horimoto, K.23
Shimojima, M.24
Horimoto, T.25
Goto, H.26
Takahashi, K.27
Makino, A.28
Ishigaki, H.29
Nakayama, M.30
Okamatsu, M.31
Warshauer, D.32
Shult, P.A.33
Saito, R.34
Suzuki, H.35
Furuta, Y.36
Yamashita, M.37
Mitamura, K.38
Nakano, K.39
Nakamura, M.40
Brockman-Schneider, R.41
Mitamura, H.42
Yamazaki, M.43
Sugaya, N.44
Suresh, M.45
Ozawa, M.46
Neumann, G.47
Gern, J.48
Kida, H.49
Ogasawara, K.50
Kawaoka, Y.51
more..
-
43
-
-
33344477350
-
Chemical genetic analysis of the time course of signal transduction by JNK
-
J. J. Ventura, A. Hübner, C. Zhang, R. A. Flavell, K. M. Shokat, R. J. Davis, Chemical genetic analysis of the time course of signal transduction by JNK. Mol. Cell 21, 701-710 (2006).
-
(2006)
Mol. Cell
, vol.21
, pp. 701-710
-
-
Ventura, J.J.1
Hübner, A.2
Zhang, C.3
Flavell, R.A.4
Shokat, K.M.5
Davis, R.J.6
-
44
-
-
67449101291
-
RIG-I-mediated activation of p38 MAPK is essential for viral induction of interferon and activation of dendritic cells: Dependence on TRAF2 and TAK1
-
S. S. Mikkelsen, S. B. Jensen, S. Chiliveru, J. Melchjorsen, I. Julkunen, M. Gaestel, J. S. Arthur, R. A. Flavell, S. Ghosh, S. R. Paludan, RIG-I-mediated activation of p38 MAPK is essential for viral induction of interferon and activation of dendritic cells: Dependence on TRAF2 and TAK1. J. Biol. Chem. 284, 10774-10782 (2009).
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 10774-10782
-
-
Mikkelsen, S.S.1
Jensen, S.B.2
Chiliveru, S.3
Melchjorsen, J.4
Julkunen, I.5
Gaestel, M.6
Arthur, J.S.7
Flavell, R.A.8
Ghosh, S.9
Paludan, S.R.10
-
45
-
-
66249129026
-
TRAF6 establishes innate immune responses by activating NF-κB and IRF7 upon sensing cytosolic viral RNA and DNA
-
H. Konno, T. Yamamoto, K. Yamazaki, J. Gohda, T. Akiyama, K. Semba, H. Goto, A. Kato, T. Yujiri, T. Imai, Y. Kawaguchi, B. Su, O. Takeuchi, S. Akira, Y. Tsunetsugu-Yokota, J. Inoue, TRAF6 establishes innate immune responses by activating NF-κB and IRF7 upon sensing cytosolic viral RNA and DNA. PLOS One 4, e5674 (2009).
-
(2009)
PLOS One
, vol.4
-
-
Konno, H.1
Yamamoto, T.2
Yamazaki, K.3
Gohda, J.4
Akiyama, T.5
Semba, K.6
Goto, H.7
Kato, A.8
Yujiri, T.9
Imai, T.10
Kawaguchi, Y.11
Su, B.12
Takeuchi, O.13
Akira, S.14
Tsunetsugu-Yokota, Y.15
Inoue, J.16
-
46
-
-
68149128514
-
Mitochondrial phosphoglycerate mutase 5 uses alternate catalytic activity as a protein serine/threonine phosphatase to activate ASK1
-
K. Takeda, Y. Komuro, T. Hayakawa, H. Oguchi, Y. Ishida, S. Murakami, T. Noguchi, H. Kinoshita, Y. Sekine, S. Iemura, T. Natsume, H. Ichijo, Mitochondrial phosphoglycerate mutase 5 uses alternate catalytic activity as a protein serine/threonine phosphatase to activate ASK1. Proc. Natl. Acad. Sci. U.S.A. 106, 12301-12305 (2009).
-
(2009)
Proc. Natl. Acad. Sci. U.S.A.
, vol.106
, pp. 12301-12305
-
-
Takeda, K.1
Komuro, Y.2
Hayakawa, T.3
Oguchi, H.4
Ishida, Y.5
Murakami, S.6
Noguchi, T.7
Kinoshita, H.8
Sekine, Y.9
Iemura, S.10
Natsume, T.11
Ichijo, H.12
-
47
-
-
2942696470
-
Thioredoxin-2 inhibits mitochondria-located ASK1-mediated apoptosis in a JNK-independent manner
-
R. Zhang, R. Al-Lamki, L. Bai, J. W. Streb, J. M. Miano, J. Bradley, W. Min, Thioredoxin-2 inhibits mitochondria-located ASK1-mediated apoptosis in a JNK-independent manner. Circ. Res. 94, 1483-1491 (2004).
-
(2004)
Circ. Res.
, vol.94
, pp. 1483-1491
-
-
Zhang, R.1
Al-Lamki, R.2
Bai, L.3
Streb, J.W.4
Miano, J.M.5
Bradley, J.6
Min, W.7
-
48
-
-
0032080283
-
Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1
-
M. Saitoh, H. Nishitoh, M. Fujii, K. Takeda, K. Tobiume, Y. Sawada, M. Kawabata, K. Miyazono, H. Ichijo, Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1. EMBO J. 17, 2596-2606 (1998).
-
(1998)
EMBO J.
, vol.17
, pp. 2596-2606
-
-
Saitoh, M.1
Nishitoh, H.2
Fujii, M.3
Takeda, K.4
Tobiume, K.5
Sawada, Y.6
Kawabata, M.7
Miyazono, K.8
Ichijo, H.9
-
49
-
-
62449110463
-
Absence of autophagy results in reactive oxygen species-dependent amplification of RLR signaling
-
M. C. Tal, M. Sasai, H. K. Lee, B. Yordy, G. S. Shadel, A. Iwasaki, Absence of autophagy results in reactive oxygen species-dependent amplification of RLR signaling. Proc. Natl. Acad. Sci. U.S.A. 106, 2770-2775 (2009).
-
(2009)
Proc. Natl. Acad. Sci. U.S.A.
, vol.106
, pp. 2770-2775
-
-
Tal, M.C.1
Sasai, M.2
Lee, H.K.3
Yordy, B.4
Shadel, G.S.5
Iwasaki, A.6
-
50
-
-
0035848864
-
HIV-1 Nef inhibits ASK1- dependent death signalling providing a potential mechanism for protecting the infected host cell
-
R. Geleziunas, W. Xu, K. Takeda, H. Ichijo, W. C. Greene, HIV-1 Nef inhibits ASK1- dependent death signalling providing a potential mechanism for protecting the infected host cell. Nature 410, 834-838 (2001).
-
(2001)
Nature
, vol.410
, pp. 834-838
-
-
Geleziunas, R.1
Xu, W.2
Takeda, K.3
Ichijo, H.4
Greene, W.C.5
-
51
-
-
34147161091
-
Viral infections activate types I and III interferon genes through a common mechanism
-
K. Onoguchi, M. Yoneyama, A. Takemura, S. Akira, T. Taniguchi, H. Namiki, T. Fujita, Viral infections activate types I and III interferon genes through a common mechanism. J. Biol. Chem. 282, 7576-7581 (2007).
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 7576-7581
-
-
Onoguchi, K.1
Yoneyama, M.2
Takemura, A.3
Akira, S.4
Taniguchi, T.5
Namiki, H.6
Fujita, T.7
-
52
-
-
1342342857
-
Strategies for generation of an siRNA expression library directed against the human genome
-
M. Miyagishi, K. Taira, Strategies for generation of an siRNA expression library directed against the human genome. Oligonucleotides 13, 325-333 (2003).
-
(2003)
Oligonucleotides
, vol.13
, pp. 325-333
-
-
Miyagishi, M.1
Taira, K.2
-
53
-
-
17544375439
-
Viral mutation accelerated by nitric oxide production during infection in vivo
-
T. Akaike, S. Fujii, A. Kato, J. Yoshitake, Y. Miyamoto, T. Sawa, S. Okamoto, M. Suga, M. Asakawa, Y. Nagai, H. Maeda, Viral mutation accelerated by nitric oxide production during infection in vivo. FASEB J. 14, 1447-1454 (2000).
-
(2000)
FASEB J.
, vol.14
, pp. 1447-1454
-
-
Akaike, T.1
Fujii, S.2
Kato, A.3
Yoshitake, J.4
Miyamoto, Y.5
Sawa, T.6
Okamoto, S.7
Suga, M.8
Asakawa, M.9
Nagai, Y.10
Maeda, H.11
-
54
-
-
17144404177
-
IRF-7 is the master regulator of type-I interferon-dependent immune responses
-
K. Honda, H. Yanai, H. Negishi, M. Asagiri, M. Sato, T. Mizutani, N. Shimada, Y. Ohba, A. Takaoka, N. Yoshida, T. Taniguchi, IRF-7 is the master regulator of type-I interferon-dependent immune responses. Nature 434, 772-777 (2005).
-
(2005)
Nature
, vol.434
, pp. 772-777
-
-
Honda, K.1
Yanai, H.2
Negishi, H.3
Asagiri, M.4
Sato, M.5
Mizutani, T.6
Shimada, N.7
Ohba, Y.8
Takaoka, A.9
Yoshida, N.10
Taniguchi, T.11
-
55
-
-
0035065836
-
ASK1 is required for sustained activations of JNK/p38 MAP kinases and apoptosis
-
K. Tobiume, A. Matsuzawa, T. Takahashi, H. Nishitoh, K. Morita, K. Takeda, O. Minowa, K. Miyazono, T. Noda, H. Ichijo, ASK1 is required for sustained activations of JNK/p38 MAP kinases and apoptosis. EMBO Rep. 2, 222-228 (2001).
-
(2001)
EMBO Rep.
, vol.2
, pp. 222-228
-
-
Tobiume, K.1
Matsuzawa, A.2
Takahashi, T.3
Nishitoh, H.4
Morita, K.5
Takeda, K.6
Minowa, O.7
Miyazono, K.8
Noda, T.9
Ichijo, H.10
-
56
-
-
84865060036
-
Critical role of an antiviral stress granule containing RIG-I and PKR in viral detection and innate immunity
-
K. Onomoto, M. Jogi, J. S. Yoo, R. Narita, S. Morimoto, A. Takemura, S. Sambhara, A. Kawaguchi, S. Osari, K. Nagata, T. Matsumiya, H. Namiki, M. Yoneyama, T. Fujita, Critical role of an antiviral stress granule containing RIG-I and PKR in viral detection and innate immunity. PLOS One 7, e43031 (2012).
-
(2012)
PLOS One
, vol.7
-
-
Onomoto, K.1
Jogi, M.2
Yoo, J.S.3
Narita, R.4
Morimoto, S.5
Takemura, A.6
Sambhara, S.7
Kawaguchi, A.8
Osari, S.9
Nagata, K.10
Matsumiya, T.11
Namiki, H.12
Yoneyama, M.13
Fujita, T.14
-
57
-
-
84878351597
-
Mitochondrial localization of the antiviral signaling adaptor IPS-1 is important for its induction of caspase activation
-
T. Okazaki, M. Higuchi, Y. Gotoh, Mitochondrial localization of the antiviral signaling adaptor IPS-1 is important for its induction of caspase activation. Genes Cells 18, 493-501 (2013).
-
(2013)
Genes Cells
, vol.18
, pp. 493-501
-
-
Okazaki, T.1
Higuchi, M.2
Gotoh, Y.3
|