Cdc37/Hsp90 protein-mediated regulation of IRE1α protein activity in endoplasmic reticulum stress response and insulin synthesis in INS-1 cells

Journal of Biological Chemistry

Volumn 287, Issue 9, 2012, Pages 6266-6274

  Ota, Asuka ^a   Wang, Yibin ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOPHOSPHORYLATION; CYTOSOLIC; CYTOSOLIC DOMAINS; DIRECT INTERACTIONS; ENDOPLASMIC RETICULUM; ENDOPLASMIC RETICULUM STRESS RESPONSE; ER STRESS; PROTEIN ACTIVITY; SIGNALING MOLECULES; UNFOLDED PROTEIN RESPONSE;

BIOSYNTHESIS; CELL MEMBRANES; OLIGOMERIZATION; OLIGOMERS; PHYSIOLOGICAL MODELS; PHYSIOLOGY;

PROTEINS;

BINDING IMMUNOGLOBULIN PROTEIN; CELL CYCLE PROTEIN 37; CHAPERONE; HEAT SHOCK PROTEIN 90; INSULIN; MEMBRANE PROTEIN; PROTEIN IRE1ALPHA; UNCLASSIFIED DRUG;

ARTICLE; AUTOPHOSPHORYLATION; CELL STIMULATION; CONTROLLED STUDY; CYTOSOL; ENDOPLASMIC RETICULUM STRESS; GENE SILENCING; HELA CELL; HOMEOSTASIS; HUMAN; HUMAN CELL; INSULIN RELEASE; INSULIN SYNTHESIS; METABOLIC INHIBITION; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN INDUCTION; PROTEIN METABOLISM; PROTEIN MOTIF; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM; UNFOLDED PROTEIN RESPONSE;

AMINO ACID SEQUENCE; CELL CYCLE PROTEINS; CELLS, CULTURED; CHAPERONINS; CYTOSOL; DIMERIZATION; ENDOPLASMIC RETICULUM STRESS; ENDORIBONUCLEASES; GLUCOSE; HELA CELLS; HSP90 HEAT-SHOCK PROTEINS; HUMANS; INSULIN; INSULIN-SECRETING CELLS; MOLECULAR SEQUENCE DATA; PROTEIN STRUCTURE, TERTIARY; PROTEIN-SERINE-THREONINE KINASES; SIGNAL TRANSDUCTION;

EID: 84863158460     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.331264     Document Type: Article

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