P2X7 receptor regulates internalization of antimicrobial peptide LL-37 by human macrophages that promotes intracellular pathogen clearance

Journal of Immunology

Volumn 195, Issue 3, 2015, Pages 1191-1201

  Tang, Xiao ^a   Basavarajappa, Devaraj ^a   Haeggström, Jesper Z ^a   Wan, Min ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

CATHELICIDIN ANTIMICROBIAL PEPTIDE LL 37; CLATHRIN; PURINERGIC P2 RECEPTOR ANTAGONIST; PURINERGIC P2X7 RECEPTOR; PURINERGIC P2X7 RECEPTOR ANTAGONIST; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG; ANTIMICROBIAL CATIONIC PEPTIDE; CAP18 LIPOPOLYSACCHARIDE-BINDING PROTEIN; PURINERGIC P2X RECEPTOR ANTAGONIST; SMALL INTERFERING RNA;

AMINO ACID SEQUENCE; ARTICLE; CAVEOLA; CELL TRANSPORT; CONTROLLED STUDY; DOSE RESPONSE; ENDOCYTOSIS; GENE; GENE SILENCING; HUMAN; HUMAN CELL; IMMUNOMODULATION; INTERNALIZATION; LIPID RAFT; LYSOSOME; MACROPHAGE; NEUTROPHIL; P2X7R GENE; PATHOGEN CLEARANCE; PRIORITY JOURNAL; TEMPERATURE; BACTERIUM; CELL LINE; CELL MEMBRANE; GENETICS; HOST PATHOGEN INTERACTION; IMMUNOLOGY; METABOLISM; PROTEIN TRANSPORT; RNA INTERFERENCE;

ANTIMICROBIAL CATIONIC PEPTIDES; BACTERIA; CELL LINE; CLATHRIN; ENDOCYTOSIS; HOST-PATHOGEN INTERACTIONS; HUMANS; LYSOSOMES; MACROPHAGES; MEMBRANE MICRODOMAINS; NEUTROPHILS; PROTEIN TRANSPORT; PURINERGIC P2X RECEPTOR ANTAGONISTS; REACTIVE OXYGEN SPECIES; RECEPTORS, PURINERGIC P2X7; RNA INTERFERENCE; RNA, SMALL INTERFERING;

EID: 84937709569     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1402845     Document Type: Article

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