Evaluation of the effects of peptide antibiotics human β-defensins-1/-2 and LL-37 on histamine release and prostaglandin D2 production from mast cells

European Journal of Immunology

Volumn 31, Issue 4, 2001, Pages 1066-1075

  Niyonsaba, François ^a   Someya, Akimasa ^a   Hirata, Michimasa ^b   Ogawa, Hideoki ^a   Nagaoka, Isao ^a  

^a JUNTENDO UNIVERSITY   (Japan)

^b IWATE MEDICAL UNIVERSITY   (Japan)

Author keywords

Antibacterial peptide; G protein; Histamine; Mast cell

Indexed keywords

1 [[6 (3 METHOXYESTRA 1,3,5(10) TRIEN 17BETA YL)AMINO]HEXYL] 1H PYRROLE 2,5 DIONE; BETA DEFENSIN 1; BETA DEFENSIN 2; CALCIUM CHELATING AGENT; CALCIUM ION; CATHELICIDIN; CATHELICIDIN ANTIMICROBIAL PEPTIDE LL 37; CYCLOOXYGENASE 1; CYCLOOXYGENASE 1 INHIBITOR; CYCLOOXYGENASE 2 INHIBITOR; DEFENSIN; ETHYLENE GLYCOL 1,2 BIS(2 AMINOPHENYL) ETHER N,N,N',N' TETRAACETIC ACID ACETOXY METHYL ESTER; GUANINE NUCLEOTIDE BINDING PROTEIN; HISTAMINE; INDOMETACIN; N (2 CYCLOHEXYLOXY 4 NITROPHENYL)METHANESULFONAMIDE; PERTUSSIS TOXIN; PHOSPHOLIPASE C; PHOSPHOLIPASE C INHIBITOR; POLYPEPTIDE ANTIBIOTIC AGENT; PROSTAGLANDIN D2; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIMICROBIAL ACTIVITY; ARTICLE; CALCIUM MOBILIZATION; CELL FUNCTION; CELL INTERACTION; CONTROLLED STUDY; EPITHELIUM; EPITHELIUM CELL; HISTAMINE RELEASE; HOST RESISTANCE; INFLAMMATION; MALE; MAST CELL; MICROORGANISM; MODULATION; NONHUMAN; PERITONEUM MAST CELL; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS; PROTEIN EXPRESSION; RAT;

EID: 0035058454     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/1521-4141(200104)31:4<1066::aid-immu1066>3.0.co;2-%23     Document Type: Article

References (47)

1. Antimicrobial peptides in mammalian and insect host defence
2. Peptide antibiotics and their role in innate immunity
3. Epithelial antimicrobial peptides: Review and significance for oral applications
4. Mapping of the gene encoding human β-defensin-2 (DEFB2) to chromosome region 8p22-p23.1
5. A peptide antibiotic from human skin
6. The peptide antibiotic LL-37/hCAP-18 is expressed in epithelia of the human lung where it has broad antimicrobial activity at the airway surface
7. Role of CCAAT/enhancer-binding protein site in transcription of human neutrophil peptide-1 and -3 defensin genes
8. Expression of natural peptide antibiotics in human skin
9. Human β-defensin-1 is a salt-sensitive antibiotic in lung that is inactivated in cystic fibrosis
10. Human β-defensin-1: An antimicrobial peptide of urogenital tissues
11. Epithelial peptide antibiotics
12. Human β-defensin-2 is a salt-sensitive peptide antibiotic expressed in human lung
13. The human cationic antibacterial protein (hCAP18), a peptide antibiotic, is widely expressed in human squamous epithelia and colocalizes with interleukin-6
14. Epithelial antibiotics induced at sites of inflammation
15. The expression of the gene coding for the antibacterial peptide LL-37 is induced in human keratinocytes during inflammatory disorders
16. A novel granulocyte-derived peptide with lipopolysaccharide-neutralizing activity
17. Inflammatory effects of prostaglandin D2 in rat and human skin
18. Mast cell modulation of neutrophil influx and bacterial clearance at sites of infection through TNF-α
19. Critical protective role of mast cells in a model of acute septic peritonitis
20. Induction of human IgE synthesis in B cells by mast cells and basophils
21. Endothelin-1 induces release of histamine and leukotriene C4 from mouse bone marrow-derived mast cells
22. Substance P activates the release of histamine from human skin mast cells through a pertussis toxin-sensitive and protein kinase C-dependent mechanism
23. Monocyte chemotactic protein-1 provokes mast cell aggregation and [3H]5HT release
24. Purification, primary structure, and biological activity of guinea pig neutrophil cationic peptides
25. Neutrophil defensins induce histamine secretion from mast cells: Mechanisms of action
26. Mast cell subsets in the rat distinguished immunohistochemically by their content of serine proteinases
27. Peptidergic pathway in human skin and rat peritoneal mast cell activation
28. Cyclooxygenase-2- dependent delayed prostaglandin D2 generation is initiated by nerve growth factor in rat peritoneal mast cells
29. fMLP-induced arachidonic acid release in db-cAMP-differentiated HL-60 cells is independent of phosphatidylinositol-4,5-biphosphate-specific phospholipase C activation and cytosolic phospholipase A2 activation
30. New concepts about the mast cell
31. Heterotrimeric G protein signaling: Roles in immune function and fine-tuning by RGS proteins
32. G-protein regulatory pathways: Rocketing into the twenty-first century
33. Calcium signaling
34. Differential calcium effects on prostaglandin D2 generation and histamine release from isolated rat peritoneal mast cells
35. Differential release of histamine and prostaglandin D2 in rat peritoneal mast cells: Roles of cytosolic calcium and protein tyrosine kinases
36. Primary structure of prostaglandin G/H synthase from sheep vesicular gland determined from the complementary DNA sequence
37. The aspirin and heme-binding sites of ovine and murine prostaglandin endoperoxidase synthases
38. Ligand-induced prostaglandin synthesis requires expression of the TIS10/PGS-2 prostaglandin synthase gene in murine fibroblasts and macrophages
39. cDNA cloning and functional activity of a glucocorticoid-regulated inflammatory cyclooxygenase
40. Defensins: Key players or bystanders in infection, injury, and repair of the lung?
41. Synergistic actions of antibacterial neutrophil defensins and cathelicidins
42. Synergistic and additive killing by antimicrobial factors found in human airway surface liquid
43. Innate antimicrobial activity of nasal secretions
44. Augmentation of innate host defense by expression of cathelicidin antimicrobial peptide
45. Modulation of cyclic AMP in purified rat mast cells. Responses to pharmacologic, metabolic, and physical stimuli
46. Possible mechanisms of the concentration-dependent action of substance P to induce histamine release from rat peritoneal mast cells and the effect of extracellular calcium on mast cell activation
47. Isolation of cDNA encoding guinea pig neutrophil cationic antibacterial polypeptide of 11 kDa (CAP11) and evaluation of CAP11 mRNA expression during neutrophil maturation