The cathelicidin LL-37 activates human mast cells and is degraded by mast cell tryptase: Counter-regulation by CXCL4

Journal of Immunology

Volumn 183, Issue 4, 2009, Pages 2223-2231

  Schiemann, Florian ^a   Brandt, Ernst ^a   Gross, Roland ^a   Lindner, Buko ^a   Mittelstädt, Jessica ^a   Sommerhoff, Christian P ^b   Schulmistrat, Jan ^a   Petersen, Frank ^a  

^a RESEARCH CENTER BORSTEL   (Germany)

^b UNIVERSITY OF MUNICH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CATHELICIDIN ANTIMICROBIAL PEPTIDE LL 37; CHEMOKINE; CXCL4 PROTEIN; HEPARIN; LIPOPOLYSACCHARIDE; TETRAMER; TRYPTASE; UNCLASSIFIED DRUG; ANTIMICROBIAL PEPTIDE LL-37; AUTACOID; CATHELICIDIN; THROMBOCYTE FACTOR 4;

ARTICLE; BACTERICIDAL ACTIVITY; CELL ACTIVATION; CELL INTERACTION; COMPARATIVE STUDY; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME ANALYSIS; FEEDBACK SYSTEM; HUMAN; HUMAN CELL; INFLAMMATION; LUNG ALVEOLUS CELL; MAST CELL; MAST CELL DEGRANULATION; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN DEGRADATION; PROTEIN STABILITY; CELL CULTURE; DEGRANULATION; DRUG ANTAGONISM; ENZYMOLOGY; IMMUNOLOGY; LUNG; METABOLISM; PHYSIOLOGY; PROTEIN PROCESSING; SECRETION;

CATHELICIDINS; CELL DEGRANULATION; CELLS, CULTURED; FEEDBACK, BIOCHEMICAL; HUMANS; INFLAMMATION MEDIATORS; LUNG; MAST CELLS; PLATELET FACTOR 4; PROTEIN PROCESSING, POST-TRANSLATIONAL; TRYPTASES;

EID: 70149093034     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.0803587     Document Type: Article

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