Human antimicrobial peptide LL-37 modulates proinflammatory responses induced by cytokine milieus and double-stranded RNA in human keratinocytes

Biochemical and Biophysical Research Communications

Volumn 433, Issue 4, 2013, Pages 532-537

  Chen, Xue ^a,b   Takai, Toshiro ^a   Xie, Yang ^a,c   Niyonsaba, François ^a   Okumura, Ko ^a   Ogawa, Hideoki ^a  

^a JUNTENDO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b PEKING UNIVERSITY PEOPLE S HOSPITAL   (China)

^c SUN YAT SEN UNIVERSITY   (China)

Author keywords

Double stranded RNA; IFN ; Keratinocyte proinflammatory response; LL 37; Th17 cytokines; TNF

Indexed keywords

CATHELICIDIN ANTIMICROBIAL PEPTIDE LL 37; CYTOKINE; DOUBLE STRANDED RNA; GAMMA INTERFERON; GAMMA INTERFERON INDUCIBLE PROTEIN 10; INTERLEUKIN 17; INTERLEUKIN 22; INTERLEUKIN 6; INTERLEUKIN 8; RANTES; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; ATOPIC DERMATITIS; CONTROLLED STUDY; CYTOKINE RELEASE; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IMMUNOMODULATION; KERATINOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; TH17 CELL; UPREGULATION;

AMINO ACID SEQUENCE; ANTI-INFLAMMATORY AGENTS; ANTIMICROBIAL CATIONIC PEPTIDES; CELLS, CULTURED; CHEMOKINE CCL5; CHEMOKINE CXCL10; CYTOKINES; DERMATITIS, ATOPIC; ENZYME-LINKED IMMUNOSORBENT ASSAY; HUMANS; INTERFERON-GAMMA; INTERLEUKIN-6; INTERLEUKIN-8; INTERLEUKINS; KERATINOCYTES; MOLECULAR SEQUENCE DATA; PRIMARY CELL CULTURE; PSORIASIS; RECOMBINANT PROTEINS; RNA, DOUBLE-STRANDED; TH17 CELLS; TIME FACTORS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84876486782     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2013.03.024     Document Type: Article

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