TLR8 senses bacterial RNA in human monocytes and plays a nonredundant role for recognition of Streptococcus pyogenes

Journal of Immunology

Volumn 195, Issue 3, 2015, Pages 1092-1099

  Eigenbrod, Tatjana ^a   Pelka, Karin ^b   Latz, Eicke ^b   Kreikemeyer, Bernd ^c   Dalpke, Alexander H ^a  

^a UNIVERSITY HOSPITAL HEIDELBERG   (Germany)

^b UNIVERSITY HOSPITAL BONN   (Germany)

^c UNIVERSITY OF ROSTOCK   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL RNA; BETA INTERFERON; ERYTHROMYCIN; INTERLEUKIN 6; RNA 23S; SMALL INTERFERING RNA; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 13; TOLL LIKE RECEPTOR 8; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; IL6 PROTEIN, HUMAN; TLR13 PROTEIN, MOUSE; TLR8 PROTEIN, HUMAN; TNF PROTEIN, HUMAN; TUMOR NECROSIS FACTOR ALPHA;

ACIDIFICATION; ANIMAL CELL; ANTIBIOTIC RESISTANCE; ANTIGEN RECOGNITION; ARTICLE; BACTERIUM ISOLATE; CELL ACTIVATION; CELL MATURATION; CONTROLLED STUDY; CYTOKINE RELEASE; DIMETHYLATION; GENE OVEREXPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; INNATE IMMUNITY; LISTERIA MONOCYTOGENES; LYSOSOME MEMBRANE; METHYLATION; MONOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN MOTIF; STAPHYLOCOCCUS AUREUS; STREPTOCOCCUS PYOGENES; ANIMAL; BIOSYNTHESIS; C57BL MOUSE; CELL LINE; GENETICS; IMMUNOLOGY; KNOCKOUT MOUSE; MACROPHAGE; METABOLISM; RNA INTERFERENCE; SECRETION (PROCESS);

ANIMALS; CELL LINE; HUMANS; INTERFERON-BETA; INTERLEUKIN-6; MACROPHAGES; METHYLATION; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MONOCYTES; RNA INTERFERENCE; RNA, BACTERIAL; RNA, RIBOSOMAL, 23S; RNA, SMALL INTERFERING; STREPTOCOCCUS PYOGENES; TOLL-LIKE RECEPTOR 8; TOLL-LIKE RECEPTORS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84937702724     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1403173     Document Type: Article

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