Innate immune response to streptococcus pyogenes depends on the combined activation of TLR13 and TLR2

PLoS ONE

Volumn 10, Issue 3, 2015, Pages

  Fieber, Christina ^a   Janos, Marton ^a   Koestler, Tina ^a   Gratz, Nina ^a,f   Li, Xiao Dong ^e   Castiglia, Virginia ^a   Aberle, Marion ^a   Sauert, Martina ^a   Wegner, Mareike ^b   Alexopoulou, Lena ^c   Kirschning, Carsten J ^d   Chen, Zhijian J ^e   Von Haeseler, Arndt ^a   Kovarik, Pavel ^a  

^a UNIVERSITY OF VIENNA   (Austria)

^b UNIVERSITY OF FREIBURG   (Germany)

^c CENTRE D IMMUNOLOGIE DE MARSEILLE LUMINY   (France)

^d UNIVERSITY OF DUISBURG ESSEN   (Germany)

^e UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^f ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL RNA; BETA INTERFERON; INTERLEUKIN 6; INTERLEUKIN 8; MEMBRANE PROTEIN; PROTEIN UNC93B1; RIBOSOME RNA; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 13; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR 7; TOLL LIKE RECEPTOR 8; TOLL LIKE RECEPTOR 9; TOLL LIKE RECEPTOR ADAPTOR MOLECULE 1; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; CARRIER PROTEIN; TLR13 PROTEIN, MOUSE; TLR2 PROTEIN, MOUSE; UNC93B1 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBACTERIAL ACTIVITY; ANTIGEN RECOGNITION; ARTICLE; BACTERIUM DETECTION; BACTERIUM IDENTIFICATION; BONE MARROW DERIVED MACROPHAGE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DENDRITIC CELL; ENDOSOME; GENE; GENETIC CONSERVATION; GROUP A STREPTOCOCCAL INFECTION; HOST PATHOGEN INTERACTION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATION; INNATE IMMUNITY; INTERNALIZATION; MOLECULAR RECOGNITION; MOUSE; NONHUMAN; PHAGOCYTOSIS; PHYLOGENY; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN RNA BINDING; RECEPTOR UPREGULATION; STREPTOCOCCUS PYOGENES; TLR13 GENE; ANIMAL; C57BL MOUSE; GENETICS; HEK293 CELL LINE; IMMUNOLOGY; KNOCKOUT MOUSE; METABOLISM;

ANIMALIA; MAMMALIA; MUS; POSIBACTERIA; RATTUS; STREPTOCOCCUS PYOGENES;

ANIMALS; HEK293 CELLS; HUMANS; IMMUNITY, INNATE; MEMBRANE TRANSPORT PROTEINS; MICE, INBRED C57BL; MICE, KNOCKOUT; PHAGOCYTOSIS; PHYLOGENY; RNA, BACTERIAL; STREPTOCOCCUS PYOGENES; TOLL-LIKE RECEPTOR 2; TOLL-LIKE RECEPTORS;

EID: 84924417249     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0119727     Document Type: Article

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