Type I Interferon Production Induced By Streptococcus Pyogenes-Derived Nucleic Acids is Required for Host Protection

PLoS Pathogens

Volumn 7, Issue 5, 2011, Pages

  Gratz, Nina ^a   Hartweger, Harald ^a   Matt, Ulrich ^b   Kratochvill, Franz ^a   Janos, Marton ^a   Sigel, Stefanie ^b   Drobits, Barbara ^c   Li, Xiao Dong ^d   Knapp, Sylvia ^b   Kovarik, Pavel ^a  

^a UNIVERSITY OF VIENNA   (Austria)

^b MEDICAL UNIVERSITY OF VIENNA   (Austria)

^c MEDICAL UNIVERSITY OF VIENNA   (Austria)

^d UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON RECEPTOR; BETA INTERFERON; CASPASE RECRUITMENT DOMAIN PROTEIN 15; CASPASE RECRUITMENT DOMAIN PROTEIN 4; INTERFERON REGULATORY FACTOR 3; INTERFERON REGULATORY FACTOR 5; MYELOID DIFFERENTIATION FACTOR 88; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR 7; TOLL LIKE RECEPTOR 9; BACTERIAL DNA; BACTERIAL RNA; INTERFERON REGULATORY FACTOR; IRF5 PROTEIN, MOUSE; MEMBRANE PROTEIN; MPYS PROTEIN, MOUSE; MYD88 PROTEIN, MOUSE; PATTERN RECOGNITION RECEPTOR; PROTEIN SERINE THREONINE KINASE; SMALL INTERFERING RNA; TBK1 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL STRAIN; CELLULITIS; COLONY FORMING UNIT; CONTROLLED STUDY; CYTOKINE PRODUCTION; DENDRITIC CELL; HOST RESISTANCE; IMMUNE RESPONSE; MACROPHAGE; MOUSE; NEUTROPHIL; NONHUMAN; NUCLEOTIDE SEQUENCE; PHAGOCYTOSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; STREPTOCOCCUS INFECTION; STREPTOCOCCUS PYOGENES; ANIMAL; BIOSYNTHESIS; C57BL MOUSE; CELL CULTURE; FLUORESCENCE MICROSCOPY; GENE SILENCING; GENETICS; IMMUNOLOGY; INNATE IMMUNITY; METABOLISM; MICROBIOLOGY; MORTALITY; NEUTROPHIL CHEMOTAXIS; POLYMERASE CHAIN REACTION;

BACTERIA (MICROORGANISMS); MUS; POSIBACTERIA; STREPTOCOCCUS PYOGENES;

ANIMALS; CELLS, CULTURED; CELLULITIS; DENDRITIC CELLS; DNA, BACTERIAL; GENE SILENCING; IMMUNITY, INNATE; INTERFERON REGULATORY FACTOR-3; INTERFERON REGULATORY FACTORS; INTERFERON-BETA; MACROPHAGES; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MICROSCOPY, FLUORESCENCE; MYELOID DIFFERENTIATION FACTOR 88; NEUTROPHIL INFILTRATION; POLYMERASE CHAIN REACTION; PROTEIN-SERINE-THREONINE KINASES; RECEPTORS, PATTERN RECOGNITION; RNA, BACTERIAL; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; STREPTOCOCCUS PYOGENES;

EID: 79958055165     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1001345     Document Type: Article

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