Genetic Inhibition of the Ubiquitin Ligase Rnf5 Attenuates Phenotypes Associated to F508del Cystic Fibrosis Mutation

Scientific Reports

Volumn 5, Issue , 2015, Pages

  Tomati, Valeria ^a   Sondo, Elvira ^a   Armirotti, Andrea ^b   Caci, Emanuela ^a   Pesce, Emanuela ^a   Marini, Monica ^a   Gianotti, Ambra ^a   Ju Jeon, Young ^c   Cilli, Michele ^d   Pistorio, Angela ^a   Mastracci, Luca ^d,e   Ravazzolo, Roberto ^a,e   Scholte, Bob ^f   Ronai, Ze'ev ^c   Galietta, Luis J V ^a   Pedemonte, Nicoletta ^a  

^a G GASLINI INSTITUTE   (Italy)

^b ISTITUTO ITALIANO DI TECNOLOGIA   (Italy)

^c BURNHAM INSTITUTE   (United States)

^d UNIVERSITY OF GENOA   (Italy)

^e UNIVERSITY OF GENOA   (Italy)

^f ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; DNA BINDING PROTEIN; RNF5 PROTEIN, HUMAN; SMALL INTERFERING RNA; UBIQUITIN PROTEIN LIGASE;

ALLELE; ANIMAL; CELL MEMBRANE; CYSTIC FIBROSIS; DISEASE MODEL; DUODENUM; GENE DELETION; GENE EXPRESSION REGULATION; GENE SILENCING; GENETIC ASSOCIATION STUDY; GENETICS; GENOTYPE; GLYCOSYLATION; HUMAN; KNOCKOUT MOUSE; METABOLISM; PHENOTYPE; RNA INTERFERENCE;

ALLELES; ANIMALS; CELL MEMBRANE; CYSTIC FIBROSIS; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; DISEASE MODELS, ANIMAL; DNA-BINDING PROTEINS; DUODENUM; GENE EXPRESSION REGULATION; GENE KNOCKDOWN TECHNIQUES; GENE SILENCING; GENETIC ASSOCIATION STUDIES; GENOTYPE; GLYCOSYLATION; HUMANS; MICE, KNOCKOUT; PHENOTYPE; RNA INTERFERENCE; RNA, SMALL INTERFERING; SEQUENCE DELETION; UBIQUITIN-PROTEIN LIGASES;

EID: 84937468830     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep12138     Document Type: Article

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