Rescue of epithelial HCO 3 - secretion in murine intestine by apical membrane expression of the cystic fibrosis transmembrane conductance regulator mutant F508del

Journal of Physiology

Volumn 590, Issue 21, 2012, Pages 5317-5334

  Xiao, Fang ^a   Li, Junhua ^a,b   Singh, Anurag Kumar ^a   Riederer, Brigitte ^a   Wang, Jiang ^a   Sultan, Ayesha ^a   Park, Henry ^c   Lee, Min Goo ^c   Lamprecht, Georg ^d   Scholte, Bob J ^e   De Jonge, Hugo R ^e   Seidler, Ursula ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

^b HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^c Yonsei University   (South Korea)

^d UNIVERSITY OF TÜBINGEN   (Germany)

^e ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

BICARBONATE; CHLORIDE; FORSKOLIN; PROLINE ALANINE RICH KINASE; PROTEIN C; PROTEIN KINASE; TRANSMEMBRANE CONDUCTANCE REGULATOR; UNCLASSIFIED DRUG; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; OSR1 PROTEIN, MOUSE; PROTEIN SERINE THREONINE KINASE; STK39 PROTEIN, MOUSE; TRANSCRIPTION FACTOR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANION TRANSPORT; APICAL MEMBRANE; ARTICLE; BICARBONATE SECRETION; CONTROLLED STUDY; CYSTIC FIBROSIS; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR MOUSE; DUODENUM; ENZYME PHOSPHORYLATION; IN VITRO STUDY; IN VIVO STUDY; INTESTINAL SECRETION; INTESTINE BRUSH BORDER MEMBRANE; INTESTINE CELL; INTESTINE EPITHELIUM; INTESTINE MUCOSA; MOLECULAR MECHANICS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN GLYCOSYLATION; PROTEIN TRANSPORT; SECRETION (PROCESS); SHORT CIRCUIT CURRENT; SIGNAL TRANSDUCTION; ANIMAL; CELL MEMBRANE; COLON; FEMALE; GENETICS; MALE; METABOLISM; MICROVILLUS; MUTATION;

ANIMALS; BICARBONATES; CELL MEMBRANE; CHLORIDES; COLON; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; DUODENUM; FEMALE; FORSKOLIN; INTESTINAL MUCOSA; MALE; MICE; MICE, INBRED CFTR; MICROVILLI; MUTATION; PROTEIN-SERINE-THREONINE KINASES; TRANSCRIPTION FACTORS;

EID: 84868100918     PISSN: 00223751     EISSN: 14697793     Source Type: Journal    
DOI: 10.1113/jphysiol.2012.232124     Document Type: Article

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