Rescue of Δf508-CFTR trafficking via a GRASP-dependent unconventional secretion pathway

Cell

Volumn 146, Issue 5, 2011, Pages 746-760

  Gee, Heon Yung ^a   Noh, Shin Hye ^a   Tang, Bor Luen ^b   Kim, Kyung Hwan ^a   Lee, Min Goo ^a  

^a Yonsei University College of Medicine   (South Korea)

^b NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

GOLGI REASSEMBLY STACKING PROTEIN; MEMBRANE PROTEIN; TRANSMEMBRANE CONDUCTANCE REGULATOR; UNCLASSIFIED DRUG;

ARTICLE; CELL MEMBRANE; CELL MIGRATION; CELL SURFACE; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; GENE MUTATION; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN GLYCOSYLATION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN SECRETION; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; UNFOLDED PROTEIN RESPONSE; UPREGULATION;

MUS;

EID: 80052277733     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2011.07.021     Document Type: Article

References (44)

1. M.D. Amaral CFTR and chaperones: processing and degradation J. Mol. Neurosci. 23 2004 41 48 (Pubitemid 41359188)
2. F.A. Barr, M. Puype, J. Vandekerckhove, and G. Warren GRASP65, a protein involved in the stacking of Golgi cisternae Cell 91 1997 253 262 (Pubitemid 27456392)
3. F. Becq Cystic fibrosis transmembrane conductance regulator modulators for personalized drug treatment of cystic fibrosis: progress to date Drugs 70 2010 241 259
4. S. Bernales, K.L. McDonald, and P. Walter Autophagy counterbalances endoplasmic reticulum expansion during the unfolded protein response PLoS Biol. 4 2006 e423
5. S. Bernales, F.R. Papa, and P. Walter Intracellular signaling by the unfolded protein response Annu. Rev. Cell Dev. Biol. 22 2006 487 508
6. G.M. Denning, M.P. Anderson, J.F. Amara, J. Marshall, A.E. Smith, and M.J. Welsh Processing of mutant cystic fibrosis transmembrane conductance regulator is temperature-sensitive Nature 358 1992 761 764
7. M.E. Egan, J. Glöckner-Pagel, C. Ambrose, P.A. Cahill, L. Pappoe, N. Balamuth, E. Cho, S. Canny, C.A. Wagner, J. Geibel, and M.J. Caplan Calcium-pump inhibitors induce functional surface expression of Delta F508-CFTR protein in cystic fibrosis epithelial cells Nat. Med. 8 2002 485 492 (Pubitemid 34546751)
8. H.Y. Gee, Y.W. Kim, M.J. Jo, W. Namkung, J.Y. Kim, H.W. Park, K.S. Kim, H. Kim, A. Baba, and J. Yang Synaptic scaffolding molecule binds to and regulates vasoactive intestinal polypeptide type-1 receptor in epithelial cells Gastroenterology 137 2009 607 617 617, e1-e4
9. H.Y. Gee, B.L. Tang, K.H. Kim, and M.G. Lee Syntaxin 16 binds to cystic fibrosis transmembrane conductance regulator and regulates its membrane trafficking in epithelial cells J. Biol. Chem. 285 2010 35519 35527
10. + exchanger 3 J. Biol. Chem. 281 2006 1461 1469
11. K. Hatsuzawa, T. Tamura, H. Hashimoto, H. Hashimoto, S. Yokoya, M. Miura, H. Nagaya, and I. Wada Involvement of syntaxin 18, an endoplasmic reticulum (ER)-localized SNARE protein, in ER-mediated phagocytosis Mol. Biol. Cell 17 2006 3964 3977 (Pubitemid 44330880)
12. J.B. Helms, and J.E. Rothman Inhibition by brefeldin A of a Golgi membrane enzyme that catalyses exchange of guanine nucleotide bound to ARF Nature 360 1992 352 354 (Pubitemid 23000674)
13. W. Hong SNAREs and traffic Biochim. Biophys. Acta 1744 2005 493 517
14. S.A. Jesch, T.S. Lewis, N.G. Ahn, and A.D. Linstedt Mitotic phosphorylation of Golgi reassembly stacking protein 55 by mitogen-activated protein kinase ERK2 Mol. Biol. Cell 12 2001 1811 1817 (Pubitemid 33049732)
15. M.A. Kinseth, C. Anjard, D. Fuller, G. Guizzunti, W.F. Loomis, and V. Malhotra The Golgi-associated protein GRASP is required for unconventional protein secretion during development Cell 130 2007 524 534 (Pubitemid 47198303)
16. K. Kunzelmann CFTR: interacting with everything? News Physiol. Sci. 16 2001 167 170 (Pubitemid 33713264)
17. J.H. Lee, W. Richter, W. Namkung, K.H. Kim, E. Kim, M. Conti, and M.G. Lee Dynamic regulation of cystic fibrosis transmembrane conductance regulator by competitive interactions of molecular adaptors J. Biol. Chem. 282 2007 10414 10422 (Pubitemid 47093434)
18. Y. Luo, K. McDonald, and J.W. Hanrahan Trafficking of immature DeltaF508-CFTR to the plasma membrane and its detection by biotinylation Biochem. J. 419 2009 211 219 2, 219
19. R. Manjithaya, and S. Subramani Autophagy: a broad role in unconventional protein secretion? Trends Cell Biol. 21 2011 67 73
20. R. Manjithaya, C. Anjard, W.F. Loomis, and S. Subramani Unconventional secretion of Pichia pastoris Acb1 is dependent on GRASP protein, peroxisomal functions, and autophagosome formation J. Cell Biol. 188 2010 537 546
21. S.G. Miller, L. Carnell, and H.H. Moore Post-Golgi membrane traffic: brefeldin A inhibits export from distal Golgi compartments to the cell surface but not recycling J. Cell Biol. 118 1992 267 283
22. W. Namkung, K.H. Kim, and M.G. Lee Base treatment corrects defects due to misfolding of mutant cystic fibrosis transmembrane conductance regulator Gastroenterology 129 2005 1979 1990 (Pubitemid 41772975)
23. H.L. Pahl Signal transduction from the endoplasmic reticulum to the cell nucleus Physiol. Rev. 79 1999 683 701 (Pubitemid 29330171)
24. -]i and its role in pancreatic bicarbonate secretion Gastroenterology 139 2010 620 631
25. P.M. Quinton Physiological basis of cystic fibrosis: a historical perspective Physiol. Rev. 79 1, Suppl 1999 S3 S22
26. J. Rennolds, P.N. Boyaka, S.L. Bellis, and E. Cormet-Boyaka Low temperature induces the delivery of mature and immature CFTR to the plasma membrane Biochem. Biophys. Res. Commun. 366 2008 1025 1029
27. D. Ron, and P. Walter Signal integration in the endoplasmic reticulum unfolded protein response Nat. Rev. Mol. Cell Biol. 8 2007 519 529 (Pubitemid 46985379)
28. M. Roxo-Rosa, Z. Xu, A. Schmidt, M. Neto, Z. Cai, C.M. Soares, D.N. Sheppard, and M.D. Amaral Revertant mutants G550E and 4RK rescue cystic fibrosis mutants in the first nucleotide-binding domain of CFTR by different mechanisms Proc. Natl. Acad. Sci. USA 103 2006 17891 17896 (Pubitemid 44852256)
29. C. Russell, and S.M. Stagg New insights into the structural mechanisms of the COPII coat Traffic 11 2010 303 310
30. H. Schotman, L. Karhinen, and C. Rabouille dGRASP-mediated noncanonical integrin secretion is required for Drosophila epithelial remodeling Dev. Cell 14 2008 171 182 (Pubitemid 351189181)
31. M. Schröder, and R.J. Kaufman The mammalian unfolded protein response Annu. Rev. Biochem. 74 2005 739 789 (Pubitemid 40995523)
32. J. Shorter, R. Watson, M.E. Giannakou, M. Clarke, G. Warren, and F.A. Barr GRASP55, a second mammalian GRASP protein involved in the stacking of Golgi cisternae in a cell-free system EMBO J. 18 1999 4949 4960 (Pubitemid 29443797)
33. B.L. Tang, H.Y. Gee, and M.G. Lee The cystic fibrosis transmembrane conductance regulator's expanding SNARE interactome Traffic 12 2011 364 371
34. F. Urano, X. Wang, A. Bertolotti, Y. Zhang, P. Chung, H.P. Harding, and D. Ron Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1 Science 287 2000 664 666 (Pubitemid 30070916)
35. C.L. Ward, S. Omura, and R.R. Kopito Degradation of CFTR by the ubiquitin-proteasome pathway Cell 83 1995 121 127
36. R.L. Wiseman, C.M. Haynes, and D. Ron SnapShot: The unfolded protein response Cell 140 2010 590 e2
37. J.S. Yoo, B.D. Moyer, S. Bannykh, H.M. Yoo, J.R. Riordan, and W.E. Balch Non-conventional trafficking of the cystic fibrosis transmembrane conductance regulator through the early secretory pathway J. Biol. Chem. 277 2002 11401 11409 (Pubitemid 34952907)
38. B.G. Zeiher, E. Eichwald, J. Zabner, J.J. Smith, A.P. Puga, P.B. McCray Jr.; M.R. Capecchi, M.J. Welsh, and K.R. Thomas A mouse model for the delta F508 allele of cystic fibrosis J. Clin. Invest. 96 1995 2051 2064
39. K. Zhang, H.N. Wong, B. Song, C.N. Miller, D. Scheuner, and R.J. Kaufman The unfolded protein response sensor IRE1alpha is required at 2 distinct steps in B cell lymphopoiesis J. Clin. Invest. 115 2005 268 281 (Pubitemid 40385469)
40. Gee, H.Y.; Kim, Y.W.; Jo, M.J.; Namkung, W.; Kim, J.Y.; Park, H.W.; Kim, K.S.; Kim, H.; Baba, A.; Yang, J.; et al. (2009). Synaptic scaffolding molecule binds to and regulates vasoactive intestinal polypeptide type-1 receptor in epithelial cells. Gastroenterology 137, 607-617, 617, e1-e4.
41. Gee, H.Y.; Tang, B.L.; Kim, K.H.; and Lee, M.G. (2010). Syntaxin 16 binds to cystic fibrosis transmembrane conductance regulator and regulates its membrane trafficking in epithelial cells. J. Biol. Chem. 285, 35519-35527.
42. Lee, J.H.; Richter, W.; Namkung, W.; Kim, K.H.; Kim, E.; Conti, M.; and Lee, M.G. (2007). Dynamic regulation of cystic fibrosis transmembrane conductance regulator by competitive interactions of molecular adaptors. J. Biol. Chem. 282, 10414-10422. (Pubitemid 47093434)
43. Tang, B.L.; Gee, H.Y.; and Lee, M.G. (2011). The cystic fibrosis transmembrane conductance regulator's expanding SNARE interactome. Traffic 12, 364-371.
44. Zeiher, B.G.; Eichwald, E.; Zabner, J.; Smith, J.J.; Puga, A.P.; McCray, P.B.; Jr.; Capecchi, M.R.; Welsh, M.J.; and Thomas, K.R. (1995). A mouse model for the delta F508 allele of cystic fibrosis. J. Clin. Invest. 96, 2051-2064.