Rescue of ΔF508-CFTR by the SGK1/Nedd4-2 signaling pathway

Journal of Biological Chemistry

Volumn 284, Issue 37, 2009, Pages 25241-25253

  Caohuy, Hung ^a,b   Jozwik, Catherine ^a   Pollard, Harvey ^a  

^a UNIFORMED SERVICES UNIVERSITY OF THE HEALTH SCIENCES   (United States)

^b NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APICAL PLASMA MEMBRANE; CO-IMMUNOPRECIPITATIONS; CYSTIC FIBROSIS; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATORS; DEXAMETHASONES; E3 LIGASE; EPITHELIAL CELLS; EPITHELIAL SODIUM CHANNELS; FUNCTIONAL EXPRESSION; GLUCOCORTICOID RECEPTOR; LY294002; PHOSPHATIDYLINOSITOL 3-KINASE; PLASMA MEMBRANES; REGULATED KINASE; SIGNALING PATHWAYS; SMALL INTERFERING RNA; UBIQUITIN; UBIQUITINATION; WILD TYPES;

CELL MEMBRANES; NUCLEIC ACIDS; PLASMAS; RNA; SODIUM;

SIGNALING;

2 MORPHOLINO 8 PHENYLCHROMONE; DEXAMETHASONE; MIFEPRISTONE; SMALL INTERFERING RNA; TRANSMEMBRANE CONDUCTANCE REGULATOR; UBIQUITIN PROTEIN LIGASE NEDD4; UBIQUITIN PROTEIN LIGASE NEDD4-2; UNCLASSIFIED DRUG; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR DELTA F508; ENZYME INHIBITOR; EPITHELIAL SODIUM CHANNEL; GLUCOCORTICOID; IMMEDIATE EARLY PROTEIN; NEDD4 UBIQUITIN PROTEIN LIGASES; PROTEIN SERINE THREONINE KINASE; SERUM GLUCOCORTICOID REGULATED KINASE; SERUM-GLUCOCORTICOID REGULATED KINASE; UBIQUITIN PROTEIN LIGASE;

ARTICLE; CONTROLLED STUDY; EPITHELIUM CELL; HALF LIFE TIME; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN TRANSPORT; RECEPTOR BINDING; RNA INTERFERENCE; SIGNAL TRANSDUCTION; UBIQUITINATION; WILD TYPE; BIOLOGICAL MODEL; BIOTINYLATION; FLUORESCENCE MICROSCOPY; GENETICS; METABOLISM; METHODOLOGY; MUTATION; PHOSPHORYLATION; PHYSIOLOGY; TRANSPORT AT THE CELLULAR LEVEL;

BIOLOGICAL TRANSPORT; BIOTINYLATION; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; DEXAMETHASONE; ENZYME INHIBITORS; EPITHELIAL SODIUM CHANNEL; GLUCOCORTICOIDS; HUMANS; IMMEDIATE-EARLY PROTEINS; MICROSCOPY, FLUORESCENCE; MODELS, BIOLOGICAL; MUTATION; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; SIGNAL TRANSDUCTION; UBIQUITIN-PROTEIN LIGASES;

EID: 69949130128     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.035345     Document Type: Article

References (47)

1. Cheng, S. H., Gregory, R. J., Marshall, J., Paul, S., Souza, D. W., White, G. A., O'Riordan, C. R., and Smith, A. E. (1990) Cell 63, 827-834
2. Denning, G. M., Anderson, M. P., Amara, J. F., Marshall, J., Smith, A. E., and Welsh, M. J. (1992) Nature 358, 761-764
3. Mall, M., Bleich, M., Greger, R., Schreiber, R., and Kunzelmann, K. (1998) J. Clin. Invest. 102, 15-21
4. Kunzelmann, K., Kathöfer, S., and Greger, R. (1995) Pflugers Arch. 431, 1-9
5. Boucher, R. C., Cotton, C. U., Gatzy, J. T., Knowles, M. R., and Yankaskas, J. R. (1988) J. Physiol. 405, 77-103
6. Mall, M., Grubb, B. R., Harkema, J. R., O'Neal, W. K., and Boucher, R. C. (2004) Nat. Med. 10, 487-493
7. Debonneville, C., Flores, S. Y., Kamynina, E., Plant, P. J., Tauxe, C., Thomas, M. A., Münster, C., Chraíbi, A., Pratt, J. H., Horisberger, J. D., Pearce, D., Loffing, J., and Staub, O. (2001) EMBO J. 20, 7052-7059
8. Snyder, P. M., Olson, D. R., and Thomas, B. C. (2002) J. Biol. Chem. 277, 5-8
9. Kamynina, E., Tauxe, C., and Staub, O. (2001) Am. J. Physiol. Renal Physiol. 281, F469-F477
10. Snyder, P. M., Steines, J. C., and Olson, D. R. (2004) J. Biol. Chem. 279, 5042-5046
11. Rauz, S., Walker, E. A., Hughes, S. V., Coca-Prados, M., Hewison, M., Murray, P. I., and Stewart, P. M. (2003) Invest. Ophthalmol. Vis. Sci. 44, 1643-1651
12. Pondugula, S. R., Sanneman, J. D., Wangemann, P., Milhaud, P. G., and Marcus, D. C. (2004) Am. J. Physiol. Renal Physiol. 286, F1127-F1135
13. Quesnell, R. R., Han, X., and Schultz, B. D. (2007) Am. J. Physiol. Cell Physiol. 292, C1739-C1745
14. Park, J., Leong, M. L., Buse, P., Maiyar, A. C., Firestone, G. L., and Hemmings, B. A. (1999) EMBO J. 18, 3024-3033
15. Kobayashi, T., and Cohen, P. (1999) Biochem. J. 339, 319-328
16. Thomas, C. P., Campbell, J. R., Wright, P. J., and Husted, R. F. (2004) Am. J. Physiol. Lung Cell Mol. Physiol. 287, L843-L851
17. Lang, F., Henke, G., Embark, H. M., Waldegger, S., Palmada, M., Böhmer, C., and Vallon, V. (2003) Cell. Physiol. Biochem. 13, 41-50
18. Dieter, M., Palmada, M., Rajamanickam, J., Aydin, A., Busjahn, A., Boehmer, C., Luft, F. C., and Lang, F. (2004) Obes. Res. 12, 862-870
19. Wagner, C. A., Ott, M., Klingel, K., Beck, S., Melzig, J., Friedrich, B., Wild, K. N., Bröer, S., Moschen, I., Albers, A., Waldegger, S., Tümmler, B., Egan, M. E., Geibel, J. P., Kandolf, R., and Lang, F. (2001) Cell. Physiol. Biochem. 11, 209-218
20. Sato, J. D., Chapline, M. C., Thibodeau, R., Frizzell, R. A., and Stanton, B. A. (2007) Cell. Physiol. Biochem. 20, 91-98
21. Schoumacher, R. A., Ram, J., Iannuzzi, M. C., Bradbury, N. A., Wallace, R. W., Hon, C. T., Kelly, D. R., Schmid, S. M., Gelder, F. B., Rado, T. A., and Frizzell, R. A. (1990) Proc. Natl. Acad. Sci. U.S.A. 87, 4012-4016
22. Drumm, M. L., Pope, H. A., Cliff, W. H., Rommens, J. M., Marvin, S. A., Tsui, L. C., Collins, F. S., Frizzell, R. A., and Wilson, J. M. (1990) Cell 62, 1227-1233
23. Lukacs, G. L., Segal, G., Kartner, N., Grinstein, S., and Zhang, F. (1997) Biochem. J. 328, 353-361
24. West, M. R., and Molloy, C. R. (1996) Anal. Biochem. 241, 51-58
25. Zeitlin, P. L., Lu, L., Rhim, J., Cutting, G., Stetten, G., Kieffer, K. A., Craig, R., and Guggino, W. B. (1991) Am. J. Respir. Cell Mol. Biol. 4, 313-319
26. Seales, E. C., Jurado, G. A., Brunson, B. A., Wakefield, J. K., Frost, A. R., and Bellis, S. L. (2005) Cancer Res. 65, 4645-4652
27. Rennolds, J., Boyaka, P. N., Bellis, S. L., and Cormet-Boyaka, E. (2008) Biochem. Biophys. Res. Comm. 366, 1025-1029
28. Dalemans, W., Barbry, P., Champigny, G., Jallat, S., Dott, K., Dreyer, D., Crystal, R. G., Pavirani, A., Lecocq, J. P., and Lazdunski, M. (1991) Nature 354, 526-558
29. Drumm, M. L., Wilkinson, D. J., Smit, L. S., Worrell, R. T., Strong, T. V., Frizzell, R. A., Dawson, D. C., and Collins, F. S. (1991) Science 254, 1797-1799
30. Rougier, J. S., van Bemmelen, M. X., Bruce, M. C., Jespersen, T., Gavillet, B., Apothéloz, F., Cordonier, S., Staub, O., Rotin, D., and Abriel, H. (2005) Am. J. Physiol. Cell Physiol. 288, C692-C701
31. Boehmer, C., Palmada, M., Rajamanickam, J., Schniepp, R., Amara, S., and Lang, F. (2006) J. Neurochem. 97, 911-921
32. Henke, G., Maier, G., Wallisch, S., Boehmer, C., and Lang, F. (2004) J. Cell. Physiol. 199, 194-199
33. Sorkina, T., Miranda, M., Dionne, K. R., Hoover, B. R., Zahniser, N. R., and Sorkin, A. (2006) J. Neurosci. 26, 8195-8205
34. Ekberg, J., Schuetz, F., Boase, N. A., Conroy, S. J., Manning, J., Kumar, S., Poronnik, P., and Adams, D. J. (2007) J. Biol. Chem. 282, 12135-12142
35. Morrione, A., Plant, P., Valentinis, B., Staub, O., Kumar, S., Rotin, D., and Baserga, R. (1999) J. Biol. Chem. 274, 24094-24099
36. Lu, P. J., Zhou, X. Z., Shen, M., and Lu, K. P. (1999) Science 283, 1325-1328
37. Hettema, E. H., Valdez-Taubas, J., and Pelham, H. R. (2004) EMBO J. 23, 1279-1288
38. Vecchione, A., Marchese, A., Henry, P., Rotin, D., and Morrione, A. (2003) Mol. Cell. Biol. 23, 3363-3372
39. Meacham, G. C., Patterson, C., Zhang, W., Younger, J. M., and Cyr, D. M. (2001) Nat. Cell Biol. 3, 100-105
40. Younger, J. M., Ren, H. Y., Chen, L., Fan, C. Y., Fields, A., Patterson, C., and Cyr, D. M. (2004) J. Cell Biol. 167, 1075-1085
41. Plant, P. J., Lafont, F., Lecat, S., Verkade, P., Simons, K., and Rotin, D. (2000) J. Cell Biol. 149, 1473-1484
42. Shearwin-Whyatt, L. M., Brown, D. L., Wylie, F. G., Stow, J. L., and Kumar, S. (2004) J. Cell Sci. 117, 3679-3689
43. Bannykh, S. I., Bannykh, G. I., Fish, K. N., Moyer, B. D., Riordan, J. R., and Balch, W. E. (2000) Traffic 1, 852-870
44. Hicke, L. (2001) Nat. Rev. Mol. Cell Biol. 2, 195-201
45. Jilling, T., and Kirk, K. L. (1997) Int. Rev. Cytol. 172, 193-241
46. Gilbert, A., Jadot, M., Leontieva, E., Wattiaux-De Coninck, S., and Wattiaux, X. (1998) Exp. Cell Res. 242, 144-152
47. Bradbury, N. A. (1999) Physiol. Rev. 79, S175-S191