Regulation of Glutamine Carrier Proteins by RNF5 Determines Breast Cancer Response to ER Stress-Inducing Chemotherapies

Cancer Cell

Volumn 27, Issue 3, 2015, Pages 354-369

  Jeon, Young Joo ^a   Khelifa, Sihem ^b   Ratnikov, Boris ^a   Scott, David A ^a   Feng, Yongmei ^a   Parisi, Fabio ^b   Ruller, Chelsea ^a   Lau, Eric ^a   Kim, Hyungsoo ^a   Brill, Laurence M ^a   Jiang, Tingting ^b   Rimm, David L ^b   Cardiff, Robert D ^c   Mills, Gordon B ^d   Smith, Jeffrey W ^a   Osterman, Andrei L ^a   Kluger, Yuval ^b   Ronai, Ze'ev A ^a  

^a BURNHAM INSTITUTE   (United States)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARRIER PROTEIN; GLUTAMINE; MAMMALIAN TARGET OF RAPAMYCIN; PACLITAXEL; SLC1A5 PROTEIN; SLC38A2 PROTEIN; UBIQUITIN PROTEIN LIGASE; UBIQUITIN PROTEIN LIGASE RNF5; UNCLASSIFIED DRUG; AMINO ACID TRANSPORTER; ANTINEOPLASTIC AGENT; DNA BINDING PROTEIN; MTOR PROTEIN, HUMAN; RNF5 PROTEIN, HUMAN; SLC1A5 PROTEIN, HUMAN; SLC38A2 PROTEIN, HUMAN; TARGET OF RAPAMYCIN KINASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTOPHAGY; BREAST CANCER; BREAST CANCER CELL LINE; CANCER CHEMOTHERAPY; CANCER PROGNOSIS; CARCINOGENESIS; CELL DEATH; CELL PROLIFERATION; CITRIC ACID CYCLE; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; HUMAN; HUMAN CELL; MCF 7 CELL LINE; MDA MB 231 CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FOLDING; SIGNAL TRANSDUCTION; TREATMENT RESPONSE; UBIQUITINATION; ANIMAL; APOPTOSIS; BAGG ALBINO MOUSE; BREAST NEOPLASMS; C57BL MOUSE; DRUG EFFECTS; ENDOPLASMIC RETICULUM; FEMALE; GENETICS; METABOLISM; NUDE MOUSE; PHYSIOLOGY;

MOUSE MAMMARY TUMOR VIRUS;

AMINO ACID TRANSPORT SYSTEM A; AMINO ACID TRANSPORT SYSTEM ASC; ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; AUTOPHAGY; BREAST NEOPLASMS; CITRIC ACID CYCLE; DNA-BINDING PROTEINS; ENDOPLASMIC RETICULUM; ENDOPLASMIC RETICULUM STRESS; FEMALE; HUMANS; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, NUDE; PACLITAXEL; PROTEOLYSIS; SIGNAL TRANSDUCTION; TOR SERINE-THREONINE KINASES; UBIQUITIN-PROTEIN LIGASES; UBIQUITINATION;

EID: 84924250667     PISSN: 15356108     EISSN: 18783686     Source Type: Journal    
DOI: 10.1016/j.ccell.2015.02.006     Document Type: Article

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