Conformational and Temperature-sensitive Stability Defects of the ΔF508 Cystic Fibrosis Transmembrane Conductance Regulator in Post-endoplasmic Reticulum Compartments

Journal of Biological Chemistry

Volumn 276, Issue 12, 2001, Pages 8942-8950

  Sharma, Manu ^b   Benharouga, Mohamed ^b   Hu, Wei ^b   Lukacs, Gergely L ^a  

^a HOSPITAL FOR SICK CHILDREN   (Canada)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

BIOASSAY; BIOCHEMISTRY; BIOSYNTHESIS; CONFORMATIONS; MUTAGENESIS; TISSUE;

BIOCHEMICAL MEASUREMENTS;

BIOLOGICAL MEMBRANES;

CHLORIDE CHANNEL; CYCLIC AMP; DODECYL SULFATE SODIUM; GLYCEROL; MUTANT PROTEIN; PHENYLALANINE; PROTEINASE; TRANSMEMBRANE CONDUCTANCE REGULATOR;

ANIMAL CELL; ARTICLE; BIOACCUMULATION; CELL MEMBRANE; CELL SURFACE; CELLULAR DISTRIBUTION; CONFORMATIONAL TRANSITION; CONSENSUS SEQUENCE; CONTROLLED STUDY; CYSTIC FIBROSIS; ENDOPLASMIC RETICULUM; GENE DELETION; GENE MUTATION; HOMOZYGOTE; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DEGRADATION; PROTEIN DETERMINATION; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN INDUCTION; PROTEIN LOCALIZATION; PROTEIN STABILITY; PROTEIN TARGETING; TEMPERATURE DEPENDENCE; TEMPERATURE SENSITIVITY; THERMOSTABILITY; ANIMAL; CELL COMPARTMENTALIZATION; CELL LINE; CHEMISTRY; GENETICS; HAMSTER; HYDROLYSIS; METABOLISM; MUTATION; PHENOTYPE; TEMPERATURE;

ANIMALIA;

ANIMALS; CELL COMPARTMENTATION; CELL LINE; CRICETINAE; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; ENDOPLASMIC RETICULUM; HYDROLYSIS; MUTATION; PHENOTYPE; PROTEIN CONFORMATION; TEMPERATURE;

EID: 0035937847     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M009172200     Document Type: Article

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