Celastrol induces apoptosis of human osteosarcoma cells via the mitochondrial apoptotic pathway

Oncology Reports

Volumn 34, Issue 3, 2015, Pages 1129-1136

  Yu, Xiaolong ^a   Zhou, Xin ^a   Fu, Changlin ^a   Wang, Qiang ^a   Nie, Tao ^a   Zou, Fan ^a   Guo, Runsheng ^a   Liu, Hucheng ^a   Zhang, Bin ^a   Dai, Min ^a  

^a NANCHANG UNIVERSITY   (China)

Author keywords

Anticancer activity; Apoptosis; Celastrol; Human osteosarcoma; Mitochondrial pathway

Indexed keywords

CASPASE; CASPASE 9; CELASTROL; CYTOCHROME C; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN BCL 2; PROTEIN BCL XL; ANTINEOPLASTIC AGENT; TRIPTERINE; TRITERPENE;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL GROWTH; CELL PROLIFERATION; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFICACY; DRUG MECHANISM; GROWTH INHIBITION; HUMAN; HUMAN CELL; IC50; MITOCHONDRION; OSTEOSARCOMA; OSTEOSARCOMA CELL; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN FUNCTION; BONE TUMOR; CELL SURVIVAL; DRUG EFFECTS; FLOW CYTOMETRY; MITOCHONDRIAL MEMBRANE POTENTIAL; PATHOLOGY; TUMOR CELL LINE; WESTERN BLOTTING;

ANTINEOPLASTIC AGENTS; APOPTOSIS; BLOTTING, WESTERN; BONE NEOPLASMS; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; FLOW CYTOMETRY; HUMANS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA; OSTEOSARCOMA; TRITERPENES;

EID: 84937200175     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.2015.4124     Document Type: Article

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