Celastrol induces the apoptosis of breast cancer cells and inhibits their invasion via downregulation of MMP-9

Oncology Reports

Volumn 32, Issue 6, 2014, Pages 2527-2532

  Mi, Chunliu ^a   Shi, Hui ^a   Ma, Juan ^a   Han, Li Zhuo ^b   Lee, Jung Joon ^a   Jin, Xuejun ^a  

^a YANBIAN UNIVERSITY   (China)

^b Jilin Province People's Hospital   (China)

Author keywords

Apoptosis; Breast cancer; Celastrol; Metastasis; MMP 9

Indexed keywords

CASPASE 3; CASPASE 8; CELASTROL; FLICE INHIBITORY PROTEIN; GELATINASE B; INHIBITOR OF APOPTOSIS PROTEIN 1; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PLACEBO; PROTEIN BCL 2; TUMOR NECROSIS FACTOR ALPHA; ANTINEOPLASTIC AGENT; APOPTOSIS REGULATORY PROTEIN; MMP9 PROTEIN, HUMAN; TRIPTERINE; TRITERPENE;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BREAST CANCER; BREAST CANCER CELL LINE; CELLULAR DISTRIBUTION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOWN REGULATION; DRUG ISOLATION; DRUG POTENTIATION; DRUG PROTEIN BINDING; DRUG STRUCTURE; DRUG TARGETING; ENZYME INHIBITION; ENZYME REGULATION; HUMAN; HUMAN CELL; METASTASIS INHIBITION; PROTEIN CLEAVAGE; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; REAL TIME POLYMERASE CHAIN REACTION; TRIPTERYGIUM WILFORDII; WESTERN BLOTTING; BREAST TUMOR; CELL MOTION; DRUG EFFECTS; DRUG SCREENING; FEMALE; GENE EXPRESSION; GENETICS; MCF 7 CELL LINE; METABOLISM; TUMOR INVASION;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; BREAST NEOPLASMS; CELL MOVEMENT; DOWN-REGULATION; DRUG SCREENING ASSAYS, ANTITUMOR; FEMALE; GENE EXPRESSION; HUMANS; MATRIX METALLOPROTEINASE 9; MCF-7 CELLS; NEOPLASM INVASIVENESS; TRITERPENES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84914691713     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.2014.3535     Document Type: Article

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