MnSOD overexpression confers cisplatin resistance in lung adenocarcinoma via the NF-κB/Snail/Bcl-2 pathway

Free Radical Biology and Medicine

Volumn 79, Issue , 2015, Pages 127-137

  Chen, Po Ming ^a   Cheng, Ya Wen ^a   Wu, Tzu Chin ^b,c   Chen, Chih Yi ^d   Lee, Huei ^a  

^a TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^b CHUNG SHAN MEDICAL UNIVERSITY   (Taiwan)

^c CHUNG SHAN MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^d CHINA MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

Cisplatin; Free radicals; IKK NF b; Lung adenocarcinoma; MnSOD

Indexed keywords

BACULOVIRAL IAP REPEAT CONTAINING PROTEIN 3; CISPLATIN; CURCUMIN; CYTOCHROME C; I KAPPA B KINASE BETA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MANGANESE SUPEROXIDE DISMUTASE; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN MCL 1; SHORT HAIRPIN RNA; TRANSCRIPTION FACTOR RELA; TRANSCRIPTION FACTOR SNAIL; UNCLASSIFIED DRUG; VENETOCLAX; ANTINEOPLASTIC AGENT; MESSENGER RNA; SNAIL FAMILY TRANSCRIPTION FACTORS; SUPEROXIDE DISMUTASE; TRANSCRIPTION FACTOR;

AGED; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER COMBINATION CHEMOTHERAPY; CANCER GROWTH; CANCER PROGNOSIS; CANCER RESISTANCE; CANCER SURGERY; CANCER SURVIVAL; CELL VIABILITY; CLONOGENIC ASSAY; CONTROLLED STUDY; EXPRESSION VECTOR; FEMALE; GENE OVEREXPRESSION; GENE SILENCING; HUMAN; HUMAN CELL; HUMAN TISSUE; IC50; IMMUNOHISTOCHEMISTRY; LUNG ADENOCARCINOMA; LUNG CANCER CELL LINE; LUNG RESECTION; MAJOR CLINICAL STUDY; MOUSE; MTT ASSAY; NONHUMAN; OVERALL SURVIVAL; REAL TIME POLYMERASE CHAIN REACTION; RECURRENCE FREE SURVIVAL; SIGNAL TRANSDUCTION; UPREGULATION; WESTERN BLOTTING; ADENOCARCINOMA; ANIMAL; DRUG RESISTANCE; GENETICS; LUNG NEOPLASMS; METABOLISM; PATHOLOGY; XENOGRAFT;

ADENOCARCINOMA; ANIMALS; ANTINEOPLASTIC AGENTS; CISPLATIN; DRUG RESISTANCE, NEOPLASM; HETEROGRAFTS; HUMANS; LUNG NEOPLASMS; MICE; NF-KAPPA B; PROTO-ONCOGENE PROTEINS C-BCL-2; RNA, MESSENGER; SUPEROXIDE DISMUTASE; TRANSCRIPTION FACTORS;

EID: 84919883453     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2014.12.001     Document Type: Article

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