Heligmosomoides polygyrus antigens inhibit the intrinsic pathway of apoptosis by overexpression of survivin and Bcl-2 protein in CD4 T cells

Prion

Volumn 7, Issue 4, 2013, Pages 319-327

  Donskow Łysoniewska, Katarzyna ^a   Brodaczewska, Klaudia ^a   Doligalska, Maria ^a  

^a UNIVERSITY OF WARSAW   (Poland)

Author keywords

Apoptosis; Bcl 2 family protein; CD4 T cells; Cell cycle; Intestinal nematodes; Proliferation; Survivin

Indexed keywords

CASPASE 3; CASPASE 8; CYCLIN D1; MULTIDRUG RESISTANCE PROTEIN; PARASITE ANTIGEN; PROTEIN BCL 2; PROTEIN P27; SURVIVIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CD4+ T LYMPHOCYTE; CELL CYCLE PROGRESSION; CONTROLLED STUDY; CYTOKINE RELEASE; EX VIVO STUDY; HELIGMOSOMOIDES POLYGYRUS; IN VITRO STUDY; MOUSE; NEMATODIASIS; NONHUMAN; PROTEIN EXPRESSION;

APOPTOSIS; BCL-2 FAMILY PROTEIN; CD4 T CELLS; CELL CYCLE; INTESTINAL NEMATODES; PROLIFERATION; SURVIVIN;

ANIMALS; ANTIGENS, HELMINTH; APOPTOSIS; CD4-POSITIVE T-LYMPHOCYTES; DISEASE MODELS, ANIMAL; MALE; MICE; NEMATOSPIROIDES DUBIUS; PROTO-ONCOGENE PROTEINS C-BCL-2; STRONGYLIDA INFECTIONS; UP-REGULATION;

EID: 84886023398     PISSN: 19336896     EISSN: 1933690X     Source Type: Journal    
DOI: 10.4161/pri.25008     Document Type: Article

References (25)

1. Reddy A, Fried B. The use of Trichuris suis and other helminth therapies to treat Crohn's disease. Parasitol Res 2007; 100:921-7; PMID:17206504; http://dx.doi.org/10.1007/s00436-006-0416-4
2. Barthlott T, Kassiotis G, Stockinger B. T cell regulation as a side effect of homeostasis and competition. J Exp Med 2003; 197:451-60; PMID:12591903; http://dx.doi.org/10.1084/jem.20021387
3. Rzepecka J, Lucius R, Doligalska M, Beck S, Rausch S, Hartmann S. Screening for immunomodulatory proteins of the intestinal parasitic nematode Heligmosomoides polygyrus. Parasite Immunol 2006; 28:463-72; PMID:16916370; http://dx.doi.org/10.1111/j.1365-3024.2006.00891.x
4. Donskow-Łysoniewska K, Majewski P, Brodaczewska K, Józwicka K, Doligalska M. Heligmosmoides polygyrus fourth stages induce protection against DSS-induced colitis and change opioid expression in the intestine. Parasite Immunol 2012a; 34:536-46; PMID:22889318; http://dx.doi.org/10.1111/pim. 12003
5. Wilson MS, Taylor MD, O'Gorman MT, Balic A, Barr TA, Filbey K, et al. Helminth-induced CD19+CD23hi B cells modulate experimental allergic and autoimmune inflammation. Eur J Immunol 2010; 40:1682-96; PMID:20306466; http://dx.doi.org/10.1002/eji.200939721
6. Donskow-Łysoniewska K, Krawczak K, Doligalska M. Heligmosomoides polygyrus: EAE remission is correlated with different systemic cytokine profiles provoked by L4 and adult nematodes. Exp Parasitol 2012b; 132:243-8; PMID:22898371; http://dx.doi.org/10.1016/j.exppara.2012.07.009
7. Donskow K, Drela N, Doligalska M. Heligmosomoides bakeri antigen rescues CD4-positive T cells from glucocorticoid-induced apoptosis by Bcl-2 protein expression. Parasite Immunol 2011; 33:158-69; PMID:21306399; http://dx.doi.org/10.1111/j.1365-3024.2010.01262.x
8. Doligalska M, Donskow-Schmelter K, Rzepecka J, Drela N. Reduced apoptosis in BALB/c mice infected with Heligmosomoides polygyrus. Parasite Immunol 2007; 29:283-91; PMID:17518947; http://dx.doi.org/10.1111/j.1365-3024.2007.00946.x
9. Strasser A, Jost PJ, Nagata S. The many roles of FAS receptor signaling in the immune system. Immunity 2009; 30:180-92; PMID:19239902; http://dx.doi.org/10.1016/j.immuni.2009.01.001
10. Darzynkiewicz Z, Evenson D, Staiano-Coico L, Sharpless T, Melamed MR. Relationship between RNA content and progression of lymphocytes through S phase of cell cycle. Proc Natl Acad Sci U S A 1979; 76:358-62; PMID:284352; http://dx.doi.org/10.1073/pnas.76.1.358
11. Tan TT, Coussens LM. Humoral immunity, inflammation and cancer. Curr Opin Immunol 2007; 19:209-16; PMID:17276050; http://dx.doi.org/10.1016/j. coi.2007.01.001
12. Altieri DC. Survivin, versatile modulation of cell division and apoptosis in cancer. Oncogene 2003; 22:8581-9; PMID:14634620; http://dx.doi.org/10.1038/ sj.onc.1207113
13. Los M, Stroh C, Jänicke RU, Engels IH, Schulze-Osthoff K. Caspases: more than just killers? Trends Immunol 2001; 22:31-4; PMID:11286689; http://dx.doi.org/10.1016/S1471-4906(00)01814-7
14. Li F, Ambrosini G, Chu EY, Plescia J, Tognin S, Marchisio PC, et al. Control of apoptosis and mitotic spindle checkpoint by survivin. Nature 1998; 396:580-4; PMID:9859993; http://dx.doi.org/10.1038/25141
15. Adrain C, Creagh EM, Martin SJ. Apoptosis-associated release of Smac/DIABLO from mitochondria requires active caspases and is blocked by Bcl-2. EMBO J 2001; 20:6627-36; PMID:11726499; http://dx.doi.org/10.1093/emboj/20.23. 6627
16. Newton K, Strasser A. Caspases signal not only apoptosis but also antigen-induced activation in cells of the immune system. Genes Dev 2003; 17:819-25; PMID:12670865; http://dx.doi.org/10.1101/gad.1077403
17. Tamm I, Wang Y, Sausville ED, Scudiero DA, Vigna N, Oltersdorf T, et al. IAP-family protein survivin inhibits caspase activity and apoptosis induced by Fas (CD95), Bax, caspases, and anticancer drugs. Cancer Res 1998; 58:5315-20; PMID:9850056
18. Kobayashi Y, Yukiue H, Sasaki H, Fukai I, Yokoyama T, Kiriyama M, et al. Developmentally regulated expression of survivin in the human thymus. Hum Immunol 2002; 63:101-7; PMID:11821157; http://dx.doi.org/10.1016/S0198-8859(01) 00369-X
19. Chen XM, Levine SA, Splinter PL, Tietz PS, Ganong AL, Jobin C, et al. Cryptosporidium parvum activates nuclear factor kappaB in biliary epithelia preventing epithelial cell apoptosis. Gastroenterology 2001; 120:1774-83; PMID:11375958; http://dx.doi.org/10.1053/gast.2001.24850
20. Dolcet X, Llobet D, Pallares J, Matias-Guiu X. NFkB in development and progression of human cancer. Virchows Arch 2005; 446:475-82; PMID:15856292; http://dx.doi.org/10.1007/s00428-005-1264-9
21. Jaruga-Killeen E, Rayford W. TNF receptor 1 is involved in the induction of apoptosis by the cyclin dependent kinase inhibitor p27Kip1 in the prostate cancer cell line PC-3. FASEB J 2005; 19:139-41; PMID:15545300
22. Gabet AS, Mortreux F, Talarmin A, Plumelle Y, Leclercq I, Leroy A, et al. High circulating proviral load with oligoclonal expansion of HTLV-1 bearing T cells in HTLV-1 carriers with strongyloidiasis. Oncogene 2000; 19:4954-60; PMID:11042682; http://dx.doi.org/10.1038/sj.onc.1203870
23. Ruyssers NE, De Winter BY, De Man JG, Loukas A, Pearson MS, Weinstock JV, et al. Therapeutic potential of helminth soluble proteins in TNBS-induced colitis in mice. Inflamm Bowel Dis 2009; 15:491-500; PMID:19023900; http://dx.doi.org/10.1002/ibd.20787
24. Baermann G. Eine einfache methods zur anffinolung von Ankylostomum-(Nematoden)- larven in erdproben. Ned Tijdschr Geneeskd 1917; 57:131-7
25. Bradford MM. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 1976; 72:248-54; PMID:942051; http://dx.doi.org/10.1016/0003- 2697(76)90527-3