Fruits and barks extracts of Zanthozyllum heitzii a spice from Cameroon induce mitochondrial dependent apoptosis and Go/G1 phase arrest in human leukemia HL-60 cells

Biological Research

Volumn 47, Issue 1, 2014, Pages

  Pieme, Constant Anatole ^a,b   Santosh, Guru Kumar ^b   Tekwu, Emmanuel Mouafo ^a,c   Askun, Tülin ^c   Aydeniz, Hatice ^c   Ngogang, Jeanne Yonkeu ^a   Bhushan, Shashi ^b   Saxena, Ajit Kumar ^b  

^a UNIVERSITY OF YAOUNDÉ I   (Cameroon)

^b CSIR INDIAN INSTITUTE OF INTEGRATIVE MEDICINE   (India)

^c BALIKESIR UNIVERSITY   (Turkey)

Author keywords

Apoptosis; HL 60 cells; Mitochondrial membrane potential; ROS; Syringic acid; Zanthozyllum heitzii

Indexed keywords

PLANT EXTRACT; POLYPHENOL; REACTIVE OXYGEN METABOLITE; TETRAZOLIUM; THIAZOLE DERIVATIVE; THIAZOLYL BLUE;

ANALYSIS; APOPTOSIS; BARK; CAMEROON; CELL PROLIFERATION; CHEMISTRY; DRUG EFFECTS; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; FRUIT; G1 PHASE CELL CYCLE CHECKPOINT; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HL-60 CELL LINE; HUMAN; IC50; ISOLATION AND PURIFICATION; MASS SPECTROMETRY; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; PHYSIOLOGY; SPICE; ZANTHOXYLUM;

APOPTOSIS; CAMEROON; CELL PROLIFERATION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; FLOW CYTOMETRY; FRUIT; G1 PHASE CELL CYCLE CHECKPOINTS; HL-60 CELLS; HUMANS; INHIBITORY CONCENTRATION 50; MASS SPECTROMETRY; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICROSCOPY, FLUORESCENCE; MITOCHONDRIA; PLANT BARK; PLANT EXTRACTS; POLYPHENOLS; REACTIVE OXYGEN SPECIES; SPICES; TETRAZOLIUM SALTS; THIAZOLES; ZANTHOXYLUM;

EID: 84984665415     PISSN: 07169760     EISSN: 07176287     Source Type: Journal    
DOI: 10.1186/0717-6287-47-54     Document Type: Article

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