Induction of G2/M phase cell cycle arrest and apoptosis by ginsenoside Rf in human osteosarcoma MG-63 cells through the mitochondrial pathway

Oncology Reports

Volumn 31, Issue 1, 2014, Pages 305-313

  Shangguan, Wen Ji ^a   Li, He ^a   Zhang, Yue Hui ^b  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

Apoptosis; G2 M arrest; Ginsenoside Rf; Human osteosarcoma; Mitochondrial pathway

Indexed keywords

CASPASE 3; CASPASE 8; CASPASE 9; CYCLIN B1; CYCLIN DEPENDENT KINASE 1; CYTOCHROME C; GINSENOSIDE RF; PROTEIN BAX; PROTEIN BCL 2;

APOPTOSIS; ARTICLE; BAX GENE; CELL NUCLEUS; CELL STRAIN; CELL STRAIN HOS; CELL STRAIN MG 63; CELL STRAIN OS732; CELL STRAIN SAOS 2; CELL STRAIN U 2OS; CHEMOSENSITIVITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DOWN REGULATION; DRUG CYTOTOXICITY; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME ACTIVITY; G2 PHASE CELL CYCLE CHECKPOINT; HUMAN; HUMAN CELL; MITOCHONDRIAL MEMBRANE POTENTIAL; OSTEOSARCOMA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SECRETION; PROTO ONCOGENE; UPREGULATION;

APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BONE NEOPLASMS; CASPASE 3; CASPASE 8; CASPASE 9; CDC2 PROTEIN KINASE; CELL LINE, TUMOR; CELL PROLIFERATION; CYCLIN B1; CYTOCHROMES C; DRUGS, CHINESE HERBAL; GINSENOSIDES; HUMANS; M PHASE CELL CYCLE CHECKPOINTS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA; OSTEOSARCOMA; PANAX; PLANT PREPARATIONS; PROTO-ONCOGENE PROTEINS C-BCL-2; TUMOR STEM CELL ASSAY;

EID: 84891944492     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.2013.2815     Document Type: Article

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