Celastrol induces mitochondria-mediated apoptosis in hepatocellular carcinoma Bel-7402 cells

American Journal of Chinese Medicine

Volumn 43, Issue 1, 2015, Pages 137-148

  Li, Pei Pei ^a   He, Wei ^a   Yuan, Ping Fan ^a   Song, Sha Sha ^a   Lu, Jing Tao ^a   Wei, Wei ^a  

^a ANHUI MEDICAL UNIVERSITY   (China)

Author keywords

Apoptosis; Celastrol; Mitochondria mediated pathway

Indexed keywords

BETA ACTIN; CASPASE 3; CASPASE 9; CELASTROL; CYTOCHROME C; PROTEIN BAX; PROTEIN BCL 2; BAX PROTEIN, HUMAN; TRIPTERINE; TRITERPENE;

ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; CANCER INHIBITION; CELL STRUCTURE; CHINESE HERB; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA FRAGMENTATION; DOWN REGULATION; DRUG MECHANISM; ENZYME RELEASE; HEPATOCELLULAR CARCINOMA CELL LINE; HUMAN; HUMAN CELL; LIVER MITOCHONDRION; TRIPTERYGIUM WILFORDII; UPREGULATION; CHEMISTRY; DOSE RESPONSE; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; ISOLATION AND PURIFICATION; LIVER CELL CARCINOMA; LIVER TUMOR; METABOLISM; PATHOLOGY; PHYSIOLOGY; SIGNAL TRANSDUCTION; TRIPTERYGIUM; TUMOR CELL CULTURE;

APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CARCINOMA, HEPATOCELLULAR; CASPASE 3; CASPASE 9; CYTOCHROMES C; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; LIVER NEOPLASMS; MITOCHONDRIA, LIVER; PROTO-ONCOGENE PROTEINS C-BCL-2; SIGNAL TRANSDUCTION; TRIPTERYGIUM; TRITERPENES; TUMOR CELLS, CULTURED;

EID: 84928476141     PISSN: 0192415X     EISSN: 17936853     Source Type: Journal    
DOI: 10.1142/S0192415X15500093     Document Type: Article

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