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Volumn 35, Issue 6, 2015, Pages 971-1016

Exposure to Mixtures of Metals and Neurodevelopmental Outcomes: A Multidisciplinary Review Using an Adverse Outcome Pathway Framework

Author keywords

Adverse outcome pathway; Arsenic; Cadmium; Developmental; Lead; Manganese; Metal mixtures; Systematic review

Indexed keywords

AIR NAVIGATION; ARSENIC; LEAD; MANGANESE; METALS; MIXTURES; RISK ASSESSMENT;

EID: 84937073879     PISSN: 02724332     EISSN: 15396924     Source Type: Journal    
DOI: 10.1111/risa.12425     Document Type: Note
Times cited : (82)

References (188)
  • 2
    • 84857872647 scopus 로고    scopus 로고
    • Predictive environmental risk assessment of chemical mixtures: A conceptual framework
    • Backhaus T, Faust M. Predictive environmental risk assessment of chemical mixtures: A conceptual framework. Environmental Science & Technology, 2012; 46(5):2564-2573.
    • (2012) Environmental Science & Technology , vol.46 , Issue.5 , pp. 2564-2573
    • Backhaus, T.1    Faust, M.2
  • 3
    • 84937074967 scopus 로고    scopus 로고
    • Assessment of combined exposures to multiple chemicals
    • Report of a WHO/IPCS International Workshop
    • International Programme on Chemical Safety (IPCS), World Health Organization (WHO). Assessment of combined exposures to multiple chemicals. Report of a WHO/IPCS International Workshop, 2009.
    • (2009)
  • 9
    • 77956188782 scopus 로고    scopus 로고
    • The relevance of the individual genetic background for the toxicokinetics of two significant neurodevelopmental toxicants: Mercury and lead
    • Gundacker C, Gencik M, Hengstschläger M. The relevance of the individual genetic background for the toxicokinetics of two significant neurodevelopmental toxicants: Mercury and lead. Mutation Research, 2010; 705(2):130-140.
    • (2010) Mutation Research , vol.705 , Issue.2 , pp. 130-140
    • Gundacker, C.1    Gencik, M.2    Hengstschläger, M.3
  • 10
    • 64249135145 scopus 로고    scopus 로고
    • Lead and cadmium synergistically enhance the expression of divalent metal transporter 1 protein in central nervous system of developing rats
    • Gu C, Chen S, Xu X, Zheng L, Li Y, Wu K, Liu J, Qi Z, Han D, Chen G, Huo, X. Lead and cadmium synergistically enhance the expression of divalent metal transporter 1 protein in central nervous system of developing rats. Neurochemical Research, 2009; 34(6):1150-1156.
    • (2009) Neurochemical Research , vol.34 , Issue.6 , pp. 1150-1156
    • Gu, C.1    Chen, S.2    Xu, X.3    Zheng, L.4    Li, Y.5    Wu, K.6    Liu, J.7    Qi, Z.8    Han, D.9    Chen, G.10    Huo, X.11
  • 11
    • 37849015396 scopus 로고    scopus 로고
    • Low blood lead levels associated with clinically diagnosed attention-deficit/hyperactivity disorder and mediated by weak cognitive control
    • Nigg JT, Knottnerus GM, Martel MM, Nikolas M, Cavanagh K, Karmaus W, Rappley MD. Low blood lead levels associated with clinically diagnosed attention-deficit/hyperactivity disorder and mediated by weak cognitive control. Biological Psychiatry, 2008; 63(3):325-331.
    • (2008) Biological Psychiatry , vol.63 , Issue.3 , pp. 325-331
    • Nigg, J.T.1    Knottnerus, G.M.2    Martel, M.M.3    Nikolas, M.4    Cavanagh, K.5    Karmaus, W.6    Rappley, M.D.7
  • 12
    • 0003815871 scopus 로고    scopus 로고
    • Atlanta, GA: U.S. Department of Health and Human Services, Public Health Service
    • Agency for Toxic Substances and Disease Registry (ATSDR). Toxicological Profile for Lead. Atlanta, GA: U.S. Department of Health and Human Services, Public Health Service, 2007.
    • (2007) Toxicological Profile for Lead
  • 14
    • 67651005621 scopus 로고    scopus 로고
    • Co-exposure to environmental lead and manganese affects the intelligence of school-aged children
    • Kim Y, Kim BN, Hong YC, Shin MS, Yoo HJ, Kim JW, Bhang SY, Cho SC. Co-exposure to environmental lead and manganese affects the intelligence of school-aged children. Neurotoxicology, 2009; 30(4):564-571.
    • (2009) Neurotoxicology , vol.30 , Issue.4 , pp. 564-571
    • Kim, Y.1    Kim, B.N.2    Hong, Y.C.3    Shin, M.S.4    Yoo, H.J.5    Kim, J.W.6    Bhang, S.Y.7    Cho, S.C.8
  • 15
    • 32344441585 scopus 로고    scopus 로고
    • Neuropsychological correlates of hair arsenic, manganese, and cadmium levels in school-age children residing near a hazardous waste site
    • Wright RO, Amarasiriwardena C, Woolf AD, Jim R, Bellinger DC. Neuropsychological correlates of hair arsenic, manganese, and cadmium levels in school-age children residing near a hazardous waste site. Neurotoxicology, 2006; 27(2):210-216.
    • (2006) Neurotoxicology , vol.27 , Issue.2 , pp. 210-216
    • Wright, R.O.1    Amarasiriwardena, C.2    Woolf, A.D.3    Jim, R.4    Bellinger, D.C.5
  • 16
    • 0003815867 scopus 로고    scopus 로고
    • Atlanta, GA: U.S. Department of Health and Human Services, Public Health Service
    • Agency for Toxic Substances and Disease Registry (ATSDR). Toxicological Profile for Manganese. Atlanta, GA: U.S. Department of Health and Human Services, Public Health Service, 2012.
    • (2012) Toxicological Profile for Manganese
  • 17
    • 0003893915 scopus 로고    scopus 로고
    • Atlanta, GA: U.S. Department of Health and Human Services, Public Health Service
    • Agency for Toxic Substances and Disease Registry (ATSDR). Toxicological Profile for Arsenic. Atlanta, GA: U.S. Department of Health and Human Services, Public Health Service, 2007.
    • (2007) Toxicological Profile for Arsenic
  • 18
    • 70450004394 scopus 로고    scopus 로고
    • Atlanta, GA: U.S. Department of Health and Human Services, Public Health Service
    • Agency for Toxic Substances and Disease Registry (ATSDR). Toxicological Profile for Cadmium. Atlanta, GA: U.S. Department of Health and Human Services, Public Health Service, 2012.
    • (2012) Toxicological Profile for Cadmium
  • 19
    • 32444443103 scopus 로고    scopus 로고
    • Atlanta, GA: U.S. Department of Health and Human Services, Public Health Service
    • Agency for Toxic Substances and Disease Registry (ATSDR). Interaction Profile for Arsenic, Cadmium, Chromium and Lead. Atlanta, GA: U.S. Department of Health and Human Services, Public Health Service, 2004.
    • (2004) Interaction Profile for Arsenic, Cadmium, Chromium and Lead
  • 24
    • 33845346099 scopus 로고    scopus 로고
    • Exposures to environmental toxicants and attention deficit hyperactivity disorder in US children
    • Braun JM, Kahn RS, Froehlich T, Auinger P, Lanphear BP. Exposures to environmental toxicants and attention deficit hyperactivity disorder in US children. Environmental Health Perspectives, 2006; 114(12):1904-1909.
    • (2006) Environmental Health Perspectives , vol.114 , Issue.12 , pp. 1904-1909
    • Braun, J.M.1    Kahn, R.S.2    Froehlich, T.3    Auinger, P.4    Lanphear, B.P.5
  • 27
    • 84937074968 scopus 로고    scopus 로고
    • Report of the workshop on using mechanistic information in forming chemical categories, Series on Testing and Assessment, No. 138, ENV/JM/MONO(2011)8
    • Organisation for Economic Co-operation and Development (OECD). Report of the workshop on using mechanistic information in forming chemical categories, Series on Testing and Assessment, No. 138, ENV/JM/MONO(2011)8, 2011.
    • (2011)
  • 28
    • 84937074969 scopus 로고    scopus 로고
    • Guidance document on developing and assessing adverse outcome pathways, Series on Testing and Assessment, No. 184, ENV/JM/MONO(2013)6
    • Organisation for Economic Co-operation and Development (OECD). Guidance document on developing and assessing adverse outcome pathways, Series on Testing and Assessment, No. 184, ENV/JM/MONO(2013)6, 2013.
    • (2013)
  • 29
    • 84899639346 scopus 로고    scopus 로고
    • Mode of action human relevance (species concordance) framework: Evolution of the Bradford Hill considerations and comparative analysis of weight of evidence
    • Meek ME, Palermo CM, Bachman AN, North CM, Lewis RJ. Mode of action human relevance (species concordance) framework: Evolution of the Bradford Hill considerations and comparative analysis of weight of evidence. Journal of Applied Toxicology, 2014; 34:596-606.
    • (2014) Journal of Applied Toxicology , vol.34 , pp. 596-606
    • Meek, M.E.1    Palermo, C.M.2    Bachman, A.N.3    North, C.M.4    Lewis, R.J.5
  • 30
    • 84937074970 scopus 로고    scopus 로고
    • Users' handbook supplement to the guidance document for developing and assessing AOPs
    • Accessed October 2014.
    • Organisation for Economic Co-operation and Development (OECD). Users' handbook supplement to the guidance document for developing and assessing AOPs, 2014. Available at: www.aopwiki.org, Accessed October 2014.
    • (2014)
  • 35
    • 0021646571 scopus 로고
    • Effect of 54Mn and lead interaction on their binding with tissue proteins: In vitro studies
    • Kalia K, Chandra SV, Viswanathan PN. Effect of 54Mn and lead interaction on their binding with tissue proteins: In vitro studies. Industrial Health, 1984; 22(3):207-218.
    • (1984) Industrial Health , vol.22 , Issue.3 , pp. 207-218
    • Kalia, K.1    Chandra, S.V.2    Viswanathan, P.N.3
  • 36
    • 0018844639 scopus 로고
    • Effects of cadmium, manganese and aluminum on sodium-potassium-activated and magnesium-activated adenosine-triphosphatase activity and choline uptake in rat-brain synaptosomes
    • Lai JCK, Guest JF, Leung TKC, Lim L, Davison AN. Effects of cadmium, manganese and aluminum on sodium-potassium-activated and magnesium-activated adenosine-triphosphatase activity and choline uptake in rat-brain synaptosomes. Biochemical Pharmacology, 1980; 29(2):141-146.
    • (1980) Biochemical Pharmacology , vol.29 , Issue.2 , pp. 141-146
    • Lai, J.C.K.1    Guest, J.F.2    Leung, T.K.C.3    Lim, L.4    Davison, A.N.5
  • 37
    • 0019821514 scopus 로고
    • 3+ on the uptake of dopamine by synaptosomes from forebrain and from striatum of the rat
    • 3+ on the uptake of dopamine by synaptosomes from forebrain and from striatum of the rat. Biochemical Pharmacology, 1981; 30(22):3123-3125.
    • (1981) Biochemical Pharmacology , vol.30 , Issue.22 , pp. 3123-3125
    • Lai, J.C.K.1    Lim, L.2    Davison, A.N.3
  • 38
    • 0036643972 scopus 로고    scopus 로고
    • Pb and Cd poisoning during development alters cerebellar and striatal function in rats
    • Antonio MT, Lopez N, Leret ML. Pb and Cd poisoning during development alters cerebellar and striatal function in rats. Toxicology, 2002; 176(1-2):59-66.
    • (2002) Toxicology , vol.176 , Issue.1-2 , pp. 59-66
    • Antonio, M.T.1    Lopez, N.2    Leret, M.L.3
  • 40
    • 0037447621 scopus 로고    scopus 로고
    • Perinatal exposure to lead and cadmium affects anxiety-like behaviour
    • Leret ML, San Millan JA, Antonio MT. Perinatal exposure to lead and cadmium affects anxiety-like behaviour. Toxicology, 2003; 186(1-2):125-130.
    • (2003) Toxicology , vol.186 , Issue.1-2 , pp. 125-130
    • Leret, M.L.1    San Millan, J.A.2    Antonio, M.T.3
  • 42
    • 74349092974 scopus 로고    scopus 로고
    • Lipid peroxidation and ultrastructural modifications in brain after perinatal exposure to lead and/or cadmium in rat pups
    • Zhang Y-M, Liu X-Z, Lu H, Mei L, Liu Z-P. Lipid peroxidation and ultrastructural modifications in brain after perinatal exposure to lead and/or cadmium in rat pups. Biomedical and Environmental Sciences, 2009; 22(5):423-429.
    • (2009) Biomedical and Environmental Sciences , vol.22 , Issue.5 , pp. 423-429
    • Zhang, Y.-M.1    Liu, X.-Z.2    Lu, H.3    Mei, L.4    Liu, Z.-P.5
  • 43
    • 55049095136 scopus 로고    scopus 로고
    • Biochemical effects of gestational coexposure to lead and cadmium on reproductive performance, placenta, and ovary
    • Nampoothiri LP, Gupta S. Biochemical effects of gestational coexposure to lead and cadmium on reproductive performance, placenta, and ovary. Journal of Biochemical and Molecular Toxicology, 2008; 22(5):337-344.
    • (2008) Journal of Biochemical and Molecular Toxicology , vol.22 , Issue.5 , pp. 337-344
    • Nampoothiri, L.P.1    Gupta, S.2
  • 44
    • 74749104742 scopus 로고    scopus 로고
    • Sex-specific effects of gestational and lactational coexposure to lead and cadmium on hepatic phase i and phase ii xenobiotic/steroid-metabolizing enzymes and antioxidant status
    • Pillai P, Patel R, Pandya C, Gupta S. Sex-specific effects of gestational and lactational coexposure to lead and cadmium on hepatic phase i and phase ii xenobiotic/steroid-metabolizing enzymes and antioxidant status. Journal of Biochemical and Molecular Toxicology, 2009; 23(6):419-431.
    • (2009) Journal of Biochemical and Molecular Toxicology , vol.23 , Issue.6 , pp. 419-431
    • Pillai, P.1    Patel, R.2    Pandya, C.3    Gupta, S.4
  • 45
    • 78650443603 scopus 로고    scopus 로고
    • Biochemical and molecular effects of gestational and lactational coexposure to lead and cadmium on ovarian steroidogenesis are associated with oxidative stress in F1 generation rats
    • Pillai P, Pandya C, Gupta S, Gupta S. Biochemical and molecular effects of gestational and lactational coexposure to lead and cadmium on ovarian steroidogenesis are associated with oxidative stress in F1 generation rats. Journal of Biochemical and Molecular Toxicology, 2010; 24(6):384-394.
    • (2010) Journal of Biochemical and Molecular Toxicology , vol.24 , Issue.6 , pp. 384-394
    • Pillai, P.1    Pandya, C.2    Gupta, S.3    Gupta, S.4
  • 46
    • 0036451601 scopus 로고    scopus 로고
    • Effects of combined exposure to lead and cadmium on pituitary membrane of female rats
    • Pillai A, Laxmi Priya PN, Gupta S. Effects of combined exposure to lead and cadmium on pituitary membrane of female rats. Archives of Toxicology, 2002; 76(12):671-675.
    • (2002) Archives of Toxicology , vol.76 , Issue.12 , pp. 671-675
    • Pillai, A.1    Laxmi Priya, P.N.2    Gupta, S.3
  • 47
    • 0037333680 scopus 로고    scopus 로고
    • Effects of combined exposure to lead and cadmium on the hypothalamic-pituitary axis function in proestrous rats
    • Pillai A, Priya L, Gupta S. Effects of combined exposure to lead and cadmium on the hypothalamic-pituitary axis function in proestrous rats. Food and Chemical Toxicology, 2003; 41(3):379-84.
    • (2003) Food and Chemical Toxicology , vol.41 , Issue.3 , pp. 379-384
    • Pillai, A.1    Priya, L.2    Gupta, S.3
  • 49
    • 84867233097 scopus 로고    scopus 로고
    • Neurobehavioral effects of lead and manganese individually and in combination in developmentally exposed rats
    • Betharia S, Maher TJ. Neurobehavioral effects of lead and manganese individually and in combination in developmentally exposed rats. Neurotoxicology, 2012; 33(5):1117-1127.
    • (2012) Neurotoxicology , vol.33 , Issue.5 , pp. 1117-1127
    • Betharia, S.1    Maher, T.J.2
  • 50
    • 0019809882 scopus 로고
    • Behavioral and neurochemical changes in rats simultaneously exposed to manganese and lead
    • Chandra AV, Ali MM, Saxena DK, Murthy RC. Behavioral and neurochemical changes in rats simultaneously exposed to manganese and lead. Archives of Toxicology, 1981; 49(1):49-56.
    • (1981) Archives of Toxicology , vol.49 , Issue.1 , pp. 49-56
    • Chandra, A.V.1    Ali, M.M.2    Saxena, D.K.3    Murthy, R.C.4
  • 51
    • 0021067937 scopus 로고
    • Effects of pre natal and post natal combined exposure to lead and manganese on brain development in rats
    • Chandra SV, Murthy RC, Saxena DK, Lal B. Effects of pre natal and post natal combined exposure to lead and manganese on brain development in rats. Industrial Health, 1983; 21(4):273-280.
    • (1983) Industrial Health , vol.21 , Issue.4 , pp. 273-280
    • Chandra, S.V.1    Murthy, R.C.2    Saxena, D.K.3    Lal, B.4
  • 52
    • 0021354301 scopus 로고
    • Concurrent exposure of lead and manganese to iron-deficient rats-Effect on lipid-peroxidation and contents of some metals in the brain
    • Malhotra KM, Murthy RC, Srivastava RS, Chandra SV. Concurrent exposure of lead and manganese to iron-deficient rats-Effect on lipid-peroxidation and contents of some metals in the brain. Journal of Applied Toxicology, 1984; 4(1):22-25.
    • (1984) Journal of Applied Toxicology , vol.4 , Issue.1 , pp. 22-25
    • Malhotra, K.M.1    Murthy, R.C.2    Srivastava, R.S.3    Chandra, S.V.4
  • 53
    • 0041848958 scopus 로고
    • A study of the relative toxicity of the molecular components of lead arsenate
    • Fairhall LT, Miller JW. A study of the relative toxicity of the molecular components of lead arsenate. Public Health Reports, 1941; 56(32):1610-1625.
    • (1941) Public Health Reports , vol.56 , Issue.32 , pp. 1610-1625
    • Fairhall, L.T.1    Miller, J.W.2
  • 55
    • 84882752671 scopus 로고    scopus 로고
    • Reversal effect of monoisoamyl dimercaptosuccinic acid (MiADMSA) for arsenic and lead induced perturbations in apoptosis and antioxidant enzymes in developing rat brain
    • Sannadi S, Kadeyalaa PK, Gottipolu RR. Reversal effect of monoisoamyl dimercaptosuccinic acid (MiADMSA) for arsenic and lead induced perturbations in apoptosis and antioxidant enzymes in developing rat brain. International Journal of Developmental Neuroscience, 2013; 31:586-597.
    • (2013) International Journal of Developmental Neuroscience , vol.31 , pp. 586-597
    • Sannadi, S.1    Kadeyalaa, P.K.2    Gottipolu, R.R.3
  • 56
    • 84886588594 scopus 로고    scopus 로고
    • Interaction effects of lead on bioavailability and pharmacokinetics of arsenic in the rat
    • Diacomanolis V, Noller BN, Ng JC. Interaction effects of lead on bioavailability and pharmacokinetics of arsenic in the rat. Environmental Geochemistry and Health, 2013; 35:757-766.
    • (2013) Environmental Geochemistry and Health , vol.35 , pp. 757-766
    • Diacomanolis, V.1    Noller, B.N.2    Ng, J.C.3
  • 57
    • 0031015552 scopus 로고    scopus 로고
    • Sequence of exposure to cadmium and arsenic determines the extent of toxic effects in male Fischer rats
    • Hochadel JF, Waalkes MP. Sequence of exposure to cadmium and arsenic determines the extent of toxic effects in male Fischer rats. Toxicology, 1997; 116(1-3):89-98.
    • (1997) Toxicology , vol.116 , Issue.1-3 , pp. 89-98
    • Hochadel, J.F.1    Waalkes, M.P.2
  • 58
    • 0018902648 scopus 로고
    • The effect of manganese administration, alone or combined with zinc, mercury and cadmium, on the tissue-levels of these elements in rats
    • Lai S, Gupta SK, Chandra SV. The effect of manganese administration, alone or combined with zinc, mercury and cadmium, on the tissue-levels of these elements in rats. Toxicology Letters, 1980; 5(3-4):203-206.
    • (1980) Toxicology Letters , vol.5 , Issue.3-4 , pp. 203-206
    • Lai, S.1    Gupta, S.K.2    Chandra, S.V.3
  • 60
    • 84957541813 scopus 로고    scopus 로고
    • CDK5-induced p-PPARc(Ser 112) downregulates GFAP via PPREs in developing rat brain: Effect of metal mixture and troglitazone in astrocytes
    • Rai A, Tripathi S, Kushwaha R, Singh P, Srivastava P, Sanyal S, Bandyopadhyay S. CDK5-induced p-PPARc(Ser 112) downregulates GFAP via PPREs in developing rat brain: Effect of metal mixture and troglitazone in astrocytes. Cell Death & Differentiation, 2014; 5:e1033, doi:10.1038/cddis.2013.514.
    • (2014) Cell Death & Differentiation , vol.5 , pp. e1033
    • Rai, A.1    Tripathi, S.2    Kushwaha, R.3    Singh, P.4    Srivastava, P.5    Sanyal, S.6    Bandyopadhyay, S.7
  • 62
    • 84873807657 scopus 로고    scopus 로고
    • Down-regulated GFAPα: A major player in heavy metal induced astrocyte damage
    • Rai A, Maurya SK, Sharma R, Ali S. Down-regulated GFAPα: A major player in heavy metal induced astrocyte damage. Toxicology Mechanisms and Methods, 2013; 23(2):99-107.
    • (2013) Toxicology Mechanisms and Methods , vol.23 , Issue.2 , pp. 99-107
    • Rai, A.1    Maurya, S.K.2    Sharma, R.3    Ali, S.4
  • 63
    • 78549247841 scopus 로고    scopus 로고
    • Characterization of developmental neurotoxicity of As, Cd, and Pb mixture: Synergistic action of metal mixture in glial and neuronal functions
    • Rai A, Maurya SK, Khare P, Srivastava A, Bandyopadhyay S. Characterization of developmental neurotoxicity of As, Cd, and Pb mixture: Synergistic action of metal mixture in glial and neuronal functions. Toxicological Sciences, 2010; 118(2):586-601.
    • (2010) Toxicological Sciences , vol.118 , Issue.2 , pp. 586-601
    • Rai, A.1    Maurya, S.K.2    Khare, P.3    Srivastava, A.4    Bandyopadhyay, S.5
  • 64
    • 17944382241 scopus 로고    scopus 로고
    • Oxidative stress induced by lead, cadmium and arsenic mixtures: 30-day, 90-day, and 180-day drinking water studies in rats: An overview
    • Fowler BA, Whittaker MH, Lipsky M, Wang GS, Chen XQ. Oxidative stress induced by lead, cadmium and arsenic mixtures: 30-day, 90-day, and 180-day drinking water studies in rats: An overview. Biometals, 2004; 17(5):567-568.
    • (2004) Biometals , vol.17 , Issue.5 , pp. 567-568
    • Fowler, B.A.1    Whittaker, M.H.2    Lipsky, M.3    Wang, G.S.4    Chen, X.Q.5
  • 65
    • 0017622373 scopus 로고
    • Effects of concurrent administration of lead, cadmium, and arsenic in rat
    • Mahaffey KR, Fowler BA. Effects of concurrent administration of lead, cadmium, and arsenic in rat. Environmental Health Perspectives, 1977; 19(Aug):165-171.
    • (1977) Environmental Health Perspectives , vol.19 , Issue.AUG. , pp. 165-171
    • Mahaffey, K.R.1    Fowler, B.A.2
  • 66
    • 0019402946 scopus 로고
    • Concurrent exposure to lead, cadmium, and arsenic-Effects on toxicity and tissue metal concentrations in the rat
    • Mahaffey KR, Capar SG, Gladen BC, Fowler BA. Concurrent exposure to lead, cadmium, and arsenic-Effects on toxicity and tissue metal concentrations in the rat. Journal of Laboratory and Clinical Medicine, 1981; 98(4):463-481.
    • (1981) Journal of Laboratory and Clinical Medicine , vol.98 , Issue.4 , pp. 463-481
    • Mahaffey, K.R.1    Capar, S.G.2    Gladen, B.C.3    Fowler, B.A.4
  • 68
    • 84880341228 scopus 로고    scopus 로고
    • Urinary delta-ALA: A potential biomarker of exposure and neurotoxic effect in rats co-treated with a mixture of lead, arsenic and manganese
    • Andrade V, Mateus ML, Batoréu MC, Aschner M, dos Santos AP. Urinary delta-ALA: A potential biomarker of exposure and neurotoxic effect in rats co-treated with a mixture of lead, arsenic and manganese. Neurotoxicology, 2013; 38:33-41.
    • (2013) Neurotoxicology , vol.38 , pp. 33-41
    • Andrade, V.1    Mateus, M.L.2    Batoréu, M.C.3    Aschner, M.4    dos Santos, A.P.5
  • 69
    • 0023107422 scopus 로고
    • Concurrent exposure to lead, manganese, and cadmium and their distribution to various brain-regions, liver, kidney, and testis of growing-rats
    • Shukla GS, Chandra SV. Concurrent exposure to lead, manganese, and cadmium and their distribution to various brain-regions, liver, kidney, and testis of growing-rats. Archives of Environmental Contamination and Toxicology, 1987; 16(3):303-310.
    • (1987) Archives of Environmental Contamination and Toxicology , vol.16 , Issue.3 , pp. 303-310
    • Shukla, G.S.1    Chandra, S.V.2
  • 72
    • 33845590148 scopus 로고    scopus 로고
    • Induction of oxidative stress in erythrocytes of male rats subchronically exposed to a mixture of eight metals found as groundwater contaminants in different parts of India
    • Jadhav SH, Sarkar SN, Aggarwal M, Tripathi HC. Induction of oxidative stress in erythrocytes of male rats subchronically exposed to a mixture of eight metals found as groundwater contaminants in different parts of India. Archives of Environmental Contamination and Toxicology, 2007; 52(1):145-151.
    • (2007) Archives of Environmental Contamination and Toxicology , vol.52 , Issue.1 , pp. 145-151
    • Jadhav, S.H.1    Sarkar, S.N.2    Aggarwal, M.3    Tripathi, H.C.4
  • 75
    • 80755163533 scopus 로고    scopus 로고
    • Exposure to airborne metals and particulate matter and risk for youth adjudicated for criminal activity
    • Haynes EN, Chen A, Ryan P, Succop P, Wright J, Dietrich KN. Exposure to airborne metals and particulate matter and risk for youth adjudicated for criminal activity. Environmental Research, 2011; 111:1243-1248.
    • (2011) Environmental Research , vol.111 , pp. 1243-1248
    • Haynes, E.N.1    Chen, A.2    Ryan, P.3    Succop, P.4    Wright, J.5    Dietrich, K.N.6
  • 77
    • 0022348921 scopus 로고
    • Main and interaction effects of metal pollutants on visual-motor performance
    • Marlowe M, Stellern J, Errera J, Moon C. Main and interaction effects of metal pollutants on visual-motor performance. Archives of Environmental Health, 1985b; 40(4):221-225.
    • (1985) Archives of Environmental Health , vol.40 , Issue.4 , pp. 221-225
    • Marlowe, M.1    Stellern, J.2    Errera, J.3    Moon, C.4
  • 78
    • 0022053847 scopus 로고
    • Main and interaction effects of metallic pollutants on cognitive-functioning
    • Moon C, Marlowe M, Stellern J, Errera J. Main and interaction effects of metallic pollutants on cognitive-functioning. Journal of Learning Disabilities, 1985; 18(4):217-221.
    • (1985) Journal of Learning Disabilities , vol.18 , Issue.4 , pp. 217-221
    • Moon, C.1    Marlowe, M.2    Stellern, J.3    Errera, J.4
  • 80
    • 79956079770 scopus 로고    scopus 로고
    • Probability of intellectual disability is associated with soil concentrations of arsenic and lead
    • McDermott S, Wu J, Cai B, Lawson A, Marjorie Aelion C. Probability of intellectual disability is associated with soil concentrations of arsenic and lead. Chemosphere, 2011; 84:31-38.
    • (2011) Chemosphere , vol.84 , pp. 31-38
    • McDermott, S.1    Wu, J.2    Cai, B.3    Lawson, A.4    Marjorie, A.C.5
  • 82
    • 84155167850 scopus 로고    scopus 로고
    • 2011. Altered heavy metals and transketolase found in autistic spectrum disorder
    • Obrenovich ME, Shamberger RJ, Lonsdale D. 2011. Altered heavy metals and transketolase found in autistic spectrum disorder. Biological Trace Element Research, 2011; 144(1-3):475-486.
    • (2011) Biological Trace Element Research , vol.144 , Issue.1-3 , pp. 475-486
    • Obrenovich, M.E.1    Shamberger, R.J.2    Lonsdale, D.3
  • 83
    • 84873992179 scopus 로고    scopus 로고
    • Association of cord blood levels of lead, arsenic, and zinc with neurodevelopmental indicators in newborns: A birth cohort study in Chitwan Valley, Nepal
    • Parajuli RP, Fujiwara T, Umezaki M, Watanabe C. Association of cord blood levels of lead, arsenic, and zinc with neurodevelopmental indicators in newborns: A birth cohort study in Chitwan Valley, Nepal. Environmental Research, 2013; 121:45-51.
    • (2013) Environmental Research , vol.121 , pp. 45-51
    • Parajuli, R.P.1    Fujiwara, T.2    Umezaki, M.3    Watanabe, C.4
  • 85
    • 84872434630 scopus 로고    scopus 로고
    • Prenatal lead and cadmium co-exposure and infant neurodevelopment at 6 months of age: The Mothers and Children's Environmental Health (MOCEH) study
    • Kim Y, Ha EH, Park H, Ha M, Kim Y, Hong YC, Kim EJ, Kim BN. Prenatal lead and cadmium co-exposure and infant neurodevelopment at 6 months of age: The Mothers and Children's Environmental Health (MOCEH) study. Neurotoxicology, 2013; 35:15-22.
    • (2013) Neurotoxicology , vol.35 , pp. 15-22
    • Kim, Y.1    Ha, E.H.2    Park, H.3    Ha, M.4    Kim, Y.5    Hong, Y.C.6    Kim, E.J.7    Kim, B.N.8
  • 86
    • 33644779830 scopus 로고    scopus 로고
    • 2006. Graded associations of blood lead and urinary cadmium concentrations with oxidative-stress-related markers in the US population: Results from the Third National Health and Nutrition Examination Survey
    • Lee DH, Lim JS, Song K, Boo Y, Jacobs DR. 2006. Graded associations of blood lead and urinary cadmium concentrations with oxidative-stress-related markers in the US population: Results from the Third National Health and Nutrition Examination Survey. Environmental Health Perspectives, 2006; 114(3):350-354.
    • (2006) Environmental Health Perspectives , vol.114 , Issue.3 , pp. 350-354
    • Lee, D.H.1    Lim, J.S.2    Song, K.3    Boo, Y.4    Jacobs, D.R.5
  • 92
    • 39049149164 scopus 로고    scopus 로고
    • Inhibition of cadmium-induced oxidative injury in rat primary astrocytes by the addition of antioxidants and the reduction of intracellular calcium
    • Yang C-S, Tzou B-C, Liu Y-P, Tsai M-J, Shyue S-K, Tzeng S-F. Inhibition of cadmium-induced oxidative injury in rat primary astrocytes by the addition of antioxidants and the reduction of intracellular calcium. Journal of Cellular Biochemistry, 2008; 103(3):825-834.
    • (2008) Journal of Cellular Biochemistry , vol.103 , Issue.3 , pp. 825-834
    • Yang, C.-S.1    Tzou, B.-C.2    Liu, Y.-P.3    Tsai, M.-J.4    Shyue, S.-K.5    Tzeng, S.-F.6
  • 93
    • 34447297791 scopus 로고    scopus 로고
    • Effects of perinatal exposure to low-dose cadmium on thyroid hormone-related and sex hormone receptor gene expressions in brain of offspring
    • Ishitobi H, Mori K, Yoshida K, Watanabe C. Effects of perinatal exposure to low-dose cadmium on thyroid hormone-related and sex hormone receptor gene expressions in brain of offspring. Neurotoxicology, 2007; 28(4):790-797.
    • (2007) Neurotoxicology , vol.28 , Issue.4 , pp. 790-797
    • Ishitobi, H.1    Mori, K.2    Yoshida, K.3    Watanabe, C.4
  • 95
    • 2142714539 scopus 로고    scopus 로고
    • Endocrine disruption by cadmium, a common environmental toxicant with paradoxical effects on reproduction
    • Henson MC, Chedrese PJ. Endocrine disruption by cadmium, a common environmental toxicant with paradoxical effects on reproduction. Experimental Biology and Medicine, 2004; 229:383-392.
    • (2004) Experimental Biology and Medicine , vol.229 , pp. 383-392
    • Henson, M.C.1    Chedrese, P.J.2
  • 96
    • 0037227997 scopus 로고    scopus 로고
    • Review Article. Lead neurotoxicity in children: Basic mechanisms and clinical correlates
    • Lidsky TI, Schneider JS. Review Article. Lead neurotoxicity in children: Basic mechanisms and clinical correlates. Brain, 2003; 126:5-19.
    • (2003) Brain , vol.126 , pp. 5-19
    • Lidsky, T.I.1    Schneider, J.S.2
  • 99
    • 81055157066 scopus 로고    scopus 로고
    • Altered striatal dopamine release following a sub-acute exposure to manganese
    • Khalid M, Aoun RA, Mathews TA. Altered striatal dopamine release following a sub-acute exposure to manganese. Journal of Neuroscience Methods, 2011; 202:182-191.
    • (2011) Journal of Neuroscience Methods , vol.202 , pp. 182-191
    • Khalid, M.1    Aoun, R.A.2    Mathews, T.A.3
  • 106
    • 53149092908 scopus 로고    scopus 로고
    • Evaluation of the use of human hair for biomonitoring the deficiency of essential and exposure to toxic elements
    • Rodrigues JL, Batista BL, Nunes JA, Passos CJS, Barboa F Jr. Evaluation of the use of human hair for biomonitoring the deficiency of essential and exposure to toxic elements. Science of the Total Environment, 2008; 405:370-376.
    • (2008) Science of the Total Environment , vol.405 , pp. 370-376
    • Rodrigues, J.L.1    Batista, B.L.2    Nunes, J.A.3    Passos, C.J.S.4    Barboa, F.5
  • 108
    • 0038293437 scopus 로고    scopus 로고
    • Arsenic in groundwater in eastern New England: Occurrence, controls, and human health implications
    • Ayotte JD, Montgomery DL, Flanagan SM, Robinson KW. Arsenic in groundwater in eastern New England: Occurrence, controls, and human health implications. Environmental Science & Technology, 2003; 7(10):2075-2083.
    • (2003) Environmental Science & Technology , vol.7 , Issue.10 , pp. 2075-2083
    • Ayotte, J.D.1    Montgomery, D.L.2    Flanagan, S.M.3    Robinson, K.W.4
  • 109
    • 33846977429 scopus 로고    scopus 로고
    • The challenge posed to children's health by mixtures of toxic waste: The Tar Creek superfund site as a case-study
    • Hu H, Shine J, Wright RO. The challenge posed to children's health by mixtures of toxic waste: The Tar Creek superfund site as a case-study. Pediatric Clinics of North America, 2007; 54(1):155-175.
    • (2007) Pediatric Clinics of North America , vol.54 , Issue.1 , pp. 155-175
    • Hu, H.1    Shine, J.2    Wright, R.O.3
  • 110
    • 37349027575 scopus 로고    scopus 로고
    • Air pollution, social deprivation, and mortality: A multilevel cohort study
    • Naess O, Piro FN, Nafstad P, Smith GD, Leyland AH. Air pollution, social deprivation, and mortality: A multilevel cohort study. Epidemiology, 2007; 18(6):686-694.
    • (2007) Epidemiology , vol.18 , Issue.6 , pp. 686-694
    • Naess, O.1    Piro, F.N.2    Nafstad, P.3    Smith, G.D.4    Leyland, A.H.5
  • 111
    • 0037016553 scopus 로고    scopus 로고
    • Role for brain-derived neurotrophic factor in learning and memory
    • Yamada K, Mizuno M, Nabeshima T. Role for brain-derived neurotrophic factor in learning and memory. Life Science, 2002; 70:735-744.
    • (2002) Life Science , vol.70 , pp. 735-744
    • Yamada, K.1    Mizuno, M.2    Nabeshima, T.3
  • 113
    • 0034329742 scopus 로고    scopus 로고
    • Apoptosis in neurodegenerative disorders 2000
    • Mattson M. Apoptosis in neurodegenerative disorders 2000. Nature Reviews Molecular Cell Biology, 2000; 1:120-129.
    • (2000) Nature Reviews Molecular Cell Biology , vol.1 , pp. 120-129
    • Mattson, M.1
  • 115
    • 77953613803 scopus 로고    scopus 로고
    • Review. Neuronal caspase-3 signaling: Not only cell death
    • D'Amelio M, Cavallucci V, Cecconi F. Review. Neuronal caspase-3 signaling: Not only cell death. Cell Death Different, 2010; 17:1104-1114.
    • (2010) Cell Death Different , vol.17 , pp. 1104-1114
    • D'Amelio, M.1    Cavallucci, V.2    Cecconi, F.3
  • 116
    • 54949143147 scopus 로고    scopus 로고
    • Review. Regulation of haeme oxygenase-1 for treatment of neuroinflammation and brain disorders
    • Syapin P. Review. Regulation of haeme oxygenase-1 for treatment of neuroinflammation and brain disorders. British Journal of Pharmacology, 2008; 155:623-640.
    • (2008) British Journal of Pharmacology , vol.155 , pp. 623-640
    • Syapin, P.1
  • 118
    • 0037237927 scopus 로고    scopus 로고
    • Oxidative stress and nitration in neurodegeneration: Cause, effect, or association
    • Ischiropoulos H, Beckman JS. Oxidative stress and nitration in neurodegeneration: Cause, effect, or association? Journal of Clinical Investigation, 2003; 111:163-169.
    • (2003) Journal of Clinical Investigation , vol.111 , pp. 163-169
    • Ischiropoulos, H.1    Beckman, J.S.2
  • 119
    • 58549105755 scopus 로고    scopus 로고
    • MAP'ing CNS development and cognition: An ERKsome process
    • Samuels IS, Saitta SC, Landreth GE. MAP'ing CNS development and cognition: An ERKsome process. Neuron, 2009; 61(2):160-167.
    • (2009) Neuron , vol.61 , Issue.2 , pp. 160-167
    • Samuels, I.S.1    Saitta, S.C.2    Landreth, G.E.3
  • 120
    • 17644417124 scopus 로고    scopus 로고
    • Role of ERK in hydrogen peroxide-induced cell death of human glioma cells
    • Lee WC, Choi CH, Cha SH, Oh HL, Kim YK. Role of ERK in hydrogen peroxide-induced cell death of human glioma cells. Neurochemical Research, 2005; 30(2): 263-270,
    • (2005) Neurochemical Research , vol.30 , Issue.2 , pp. 263-270
    • Lee, W.C.1    Choi, C.H.2    Cha, S.H.3    Oh, H.L.4    Kim, Y.K.5
  • 124
    • 84884232816 scopus 로고    scopus 로고
    • Cadmium and its neurotoxicity. Review article
    • Wang B, Du Y. Cadmium and its neurotoxicity. Review article. Oxidative Medicine and Cellular Longevity, 2013, Article ID 898034, http://dx.doi.org/10.1155/2013/898034.
    • (2013) Oxidative Medicine and Cellular Longevity
    • Wang, B.1    Du, Y.2
  • 126
    • 84858860778 scopus 로고    scopus 로고
    • Role of glial cells in manganese neurotoxicity
    • Filipov NM, Dodd CA. Role of glial cells in manganese neurotoxicity. Journal of Applied Toxicology, 2012; 32(5):310-317. doi: 10.1002/jat.1762.
    • (2012) Journal of Applied Toxicology , vol.32 , Issue.5 , pp. 310-317
    • Filipov, N.M.1    Dodd, C.A.2
  • 127
    • 78650472829 scopus 로고    scopus 로고
    • Manganese modulation of MAPK pathways: Effects on upstream mitogen activated protein kinase kinases and mitogen activated kinase phosphatase-1 in microglial cells
    • Crittenden PL, Filipov NM. Manganese modulation of MAPK pathways: Effects on upstream mitogen activated protein kinase kinases and mitogen activated kinase phosphatase-1 in microglial cells. Journal of Applied Toxicology, 2011; 31(1):1-10.
    • (2011) Journal of Applied Toxicology , vol.31 , Issue.1 , pp. 1-10
    • Crittenden, P.L.1    Filipov, N.M.2
  • 129
    • 0242516020 scopus 로고    scopus 로고
    • Oxidative neurotoxicity in rat cerebral cortex neurons: Synergistic effects of H2O2 and NO on apoptosis involving activation of p38 mitogen-activated protein kinase and caspase-3
    • Wang JY, Shum AYC, Ho YJ, Wang JY. Oxidative neurotoxicity in rat cerebral cortex neurons: Synergistic effects of H2O2 and NO on apoptosis involving activation of p38 mitogen-activated protein kinase and caspase-3. Journal of Neuroscience Research, 2003; 72(4):508-519.
    • (2003) Journal of Neuroscience Research , vol.72 , Issue.4 , pp. 508-519
    • Wang, J.Y.1    Shum, A.Y.C.2    Ho, Y.J.3    Wang, J.Y.4
  • 130
    • 67849133734 scopus 로고    scopus 로고
    • Calcium signaling and the development of specific neuronal connections
    • Lohmann C. Calcium signaling and the development of specific neuronal connections. Progress in Brain Research, 2009; 175:443-452.
    • (2009) Progress in Brain Research , vol.175 , pp. 443-452
    • Lohmann, C.1
  • 131
    • 79952202610 scopus 로고    scopus 로고
    • Calcium dynamics at developing synapses: Mechanisms and functions
    • Michaelson K, Lohmann C. Calcium dynamics at developing synapses: Mechanisms and functions. European Journal of Neuroscience, 2010; 32:218-223.
    • (2010) European Journal of Neuroscience , vol.32 , pp. 218-223
    • Michaelson, K.1    Lohmann, C.2
  • 134
    • 77952419467 scopus 로고    scopus 로고
    • New roles for astrocytes in developing synaptic circuits
    • Barker AJ, Ullian EM. New roles for astrocytes in developing synaptic circuits. Communicative & Integrative Biology, 2008; 1(2):207-211.
    • (2008) Communicative & Integrative Biology , vol.1 , Issue.2 , pp. 207-211
    • Barker, A.J.1    Ullian, E.M.2
  • 137
    • 0037051159 scopus 로고    scopus 로고
    • Arsenic induced changes in growth development and apoptosis in neonatal and adult brain cells in vivo and in tissue culture
    • Chattopadhyay S, Bhaumik S, Chaudhury AN, Das Gupta S. Arsenic induced changes in growth development and apoptosis in neonatal and adult brain cells in vivo and in tissue culture. Toxicology Letters, 2002; 128(1-3):73-84.
    • (2002) Toxicology Letters , vol.128 , Issue.1-3 , pp. 73-84
    • Chattopadhyay, S.1    Bhaumik, S.2    Chaudhury, A.N.3    Das Gupta, S.4
  • 138
  • 139
    • 84878552275 scopus 로고    scopus 로고
    • Cadmium-induced apoptosis in primary rat cerebral cortical neurons culture is mediated by a calcium signaling pathway
    • Yuan Y, Jiang CY, Xu H, Sun Y, Hu FF, Bian JC, Liu XZ, Gu JH, Liu ZP. Cadmium-induced apoptosis in primary rat cerebral cortical neurons culture is mediated by a calcium signaling pathway. PLoS One, 2013; 8(5):e64330.
    • (2013) PLoS One , vol.8 , Issue.5 , pp. e64330
    • Yuan, Y.1    Jiang, C.Y.2    Xu, H.3    Sun, Y.4    Hu, F.F.5    Bian, J.C.6    Liu, X.Z.7    Gu, J.H.8    Liu, Z.P.9
  • 141
    • 84907809388 scopus 로고    scopus 로고
    • Inorganic arsenic exposure and children's neurodevelopment: A review of the evidence
    • Bellinger D. Inorganic arsenic exposure and children's neurodevelopment: A review of the evidence. Toxics, 2013; 1:2-17.
    • (2013) Toxics , vol.1 , pp. 2-17
    • Bellinger, D.1
  • 142
    • 84876405301 scopus 로고    scopus 로고
    • Subchronic exposure to arsenic disturbed the biogenic amine neurotransmitter level and the mRNA expression of synthetase in mice brains
    • Zhang J, Liu X, Zhao L, Hu S, Lis S, Piao F. Subchronic exposure to arsenic disturbed the biogenic amine neurotransmitter level and the mRNA expression of synthetase in mice brains. Neuroscience, 2013; 241:52-58.
    • (2013) Neuroscience , vol.241 , pp. 52-58
    • Zhang, J.1    Liu, X.2    Zhao, L.3    Hu, S.4    Lis, S.5    Piao, F.6
  • 143
    • 84934298088 scopus 로고    scopus 로고
    • Mechanisms of heavy metal neurotoxicity: Lead and manganese
    • Neal AP, Guilarte TR. Mechanisms of heavy metal neurotoxicity: Lead and manganese. Drug Metabolism & Toxicology, 2012; S5 http://dx.doi.org/10.4172/2157-7609.S5-002.
    • (2012) Drug Metabolism & Toxicology , vol.S5
    • Neal, A.P.1    Guilarte, T.R.2
  • 144
    • 0036067409 scopus 로고    scopus 로고
    • Astrocytes and manganese neurotoxicity
    • Hazell AS. Astrocytes and manganese neurotoxicity. Neurochemistry International, 2002; 41:271-277.
    • (2002) Neurochemistry International , vol.41 , pp. 271-277
    • Hazell, A.S.1
  • 145
    • 0034305621 scopus 로고    scopus 로고
    • Glial fibrillary acidic protein: GFAP-thirty-one years (1969-2000)
    • Eng LF, Ghirnikar RS, Lee YL. Glial fibrillary acidic protein: GFAP-thirty-one years (1969-2000). Neurochemical Research, 2000; 25(9-10):1439-1451.
    • (2000) Neurochemical Research , vol.25 , Issue.9-10 , pp. 1439-1451
    • Eng, L.F.1    Ghirnikar, R.S.2    Lee, Y.L.3
  • 147
    • 57049096895 scopus 로고    scopus 로고
    • Neuron-astrocyte signaling in the development and plasticity of neural circuits
    • Stevens B. Neuron-astrocyte signaling in the development and plasticity of neural circuits. Neurosignals, 2008; 16:278-288.
    • (2008) Neurosignals , vol.16 , pp. 278-288
    • Stevens, B.1
  • 148
    • 84876668625 scopus 로고    scopus 로고
    • Emerging roles of astrocytes in neural circuit development
    • Clarke LE, Barres BA. Emerging roles of astrocytes in neural circuit development. Nature Reviews Neuroscience, 2013; 14:311-321.
    • (2013) Nature Reviews Neuroscience , vol.14 , pp. 311-321
    • Clarke, L.E.1    Barres, B.A.2
  • 150
    • 84924942779 scopus 로고    scopus 로고
    • Lateral regulation of synaptic transmission by astrocytes
    • Feb 27. [Epub ahead of print]
    • Covelo A, Araque A. Lateral regulation of synaptic transmission by astrocytes. Neuroscience, 2015; Feb 27. pii: S0306-4522(15)00188-8. doi: 10.1016/j.neuroscience.2015.02.036. [Epub ahead of print]
    • (2015) Neuroscience
    • Covelo, A.1    Araque, A.2
  • 151
    • 1942520401 scopus 로고    scopus 로고
    • Astrocyte apoptosis: implications for neuroprotection
    • Takuma K, Baba A, Matsuda T. Astrocyte apoptosis: implications for neuroprotection. Progress in Neurobiology, 2004; 72(2):111-127.
    • (2004) Progress in Neurobiology , vol.72 , Issue.2 , pp. 111-127
    • Takuma, K.1    Baba, A.2    Matsuda, T.3
  • 152
    • 84883621413 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress signaling involvement in manganese-induced nerve cell damage in organotypic brain slice cultures
    • Xu B, Shan M, Wang F, Deng Y, Liu W, Feng S, Yang TY, Xu ZF. Endoplasmic reticulum stress signaling involvement in manganese-induced nerve cell damage in organotypic brain slice cultures. Toxicology Letters, 2013; 222(3):239-246.
    • (2013) Toxicology Letters , vol.222 , Issue.3 , pp. 239-246
    • Xu, B.1    Shan, M.2    Wang, F.3    Deng, Y.4    Liu, W.5    Feng, S.6    Yang, T.Y.7    Xu, Z.F.8
  • 155
    • 84882904365 scopus 로고    scopus 로고
    • Opening the black box: Dopamine, predictions, and learning
    • Eshel N, Tian J, Uchida N. Opening the black box: Dopamine, predictions, and learning. Trends in Cognitive Sciences, 2013; 17(9):430-431.
    • (2013) Trends in Cognitive Sciences , vol.17 , Issue.9 , pp. 430-431
    • Eshel, N.1    Tian, J.2    Uchida, N.3
  • 156
    • 84937073303 scopus 로고    scopus 로고
    • Molecular underpinnings of prefrontal cortex development in rodents provide insights into the etiology of neurodevelopmental disorders
    • Schubert D, Martens GJM, Kolk SM. Molecular underpinnings of prefrontal cortex development in rodents provide insights into the etiology of neurodevelopmental disorders. Molecular Psychiatry, 2013; 2014:1-15.
    • (2013) Molecular Psychiatry , vol.2014 , pp. 1-15
    • Schubert, D.1    Martens, G.J.M.2    Kolk, S.M.3
  • 159
    • 0035151658 scopus 로고    scopus 로고
    • Toxicology of choroid plexus: Special reference to metal-induced neurotoxicities
    • Zheng W. Toxicology of choroid plexus: Special reference to metal-induced neurotoxicities. Microscopy Research and Technique, 2001; 52(1):89-103.
    • (2001) Microscopy Research and Technique , vol.52 , Issue.1 , pp. 89-103
    • Zheng, W.1
  • 160
    • 84903754176 scopus 로고    scopus 로고
    • Systematic review and evidence integration for literature-based environmental health science assessments
    • Rooney AA, Boyles AL, Wolfe MS, Bucher JR, Thayer KA. Systematic review and evidence integration for literature-based environmental health science assessments. Environmental Health Perspectives, 2014; 122(7):711-718.
    • (2014) Environmental Health Perspectives , vol.122 , Issue.7 , pp. 711-718
    • Rooney, A.A.1    Boyles, A.L.2    Wolfe, M.S.3    Bucher, J.R.4    Thayer, K.A.5
  • 161
    • 84883262453 scopus 로고    scopus 로고
    • Instruments for assessing risk of bias and other methodological criteria of published animal studies: A systematic review
    • Krauth D, Woodruff TJ, Bero L. Instruments for assessing risk of bias and other methodological criteria of published animal studies: A systematic review. Environmental Health Perspectives, 2013; 121(9):985-992. Available at: http://dx.doi.org/10.1289/ehp.1206389.
    • (2013) Environmental Health Perspectives , vol.121 , Issue.9 , pp. 985-992
    • Krauth, D.1    Woodruff, T.J.2    Bero, L.3
  • 166
    • 79952668314 scopus 로고    scopus 로고
    • Annual research review: Development of the cerebral cortex: Implications for neurodevelopmental disorders
    • Rubenstein JLR. Annual research review: Development of the cerebral cortex: Implications for neurodevelopmental disorders. Journal of Child Psychology and Psychiatry, 2011; 52(4):339-355.
    • (2011) Journal of Child Psychology and Psychiatry , vol.52 , Issue.4 , pp. 339-355
    • Rubenstein, J.L.R.1
  • 167
    • 26944458142 scopus 로고    scopus 로고
    • Association or causation: Evaluating links between "environment and disease
    • Lucas RM, McMichael AJ. Association or causation: Evaluating links between "environment and disease." Bulletin of World Health Organization, 2005; 83(10):792-795. Available at: http://www.who.int/bulletin/volumes/83/10/792.pdf.
    • (2005) Bulletin of World Health Organization , vol.83 , Issue.10 , pp. 792-795
    • Lucas, R.M.1    McMichael, A.J.2
  • 168
    • 84918503651 scopus 로고    scopus 로고
    • Defining molecular initiating events in the adverse outcome pathway framework for risk assessment
    • Allen TE, Goodman JM, Gutsell S, Russell PJ. Defining molecular initiating events in the adverse outcome pathway framework for risk assessment. Chemical Research in Toxicology, 2014; 27(12):2100-12.
    • (2014) Chemical Research in Toxicology , vol.27 , Issue.12 , pp. 2100-2112
    • Allen, T.E.1    Goodman, J.M.2    Gutsell, S.3    Russell, P.J.4
  • 169
    • 84923590751 scopus 로고    scopus 로고
    • Proposing a scientific confidence framework to help support the application of adverse outcome pathways for regulatory purposes
    • Patlewicz G, Simon TW, Rowlands JC, Budinsky RA, Becker RA. Proposing a scientific confidence framework to help support the application of adverse outcome pathways for regulatory purposes. Regulatory Toxicology and Pharmacology, 2015; 71(3):463-477.
    • (2015) Regulatory Toxicology and Pharmacology , vol.71 , Issue.3 , pp. 463-477
    • Patlewicz, G.1    Simon, T.W.2    Rowlands, J.C.3    Budinsky, R.A.4    Becker, R.A.5
  • 171
    • 0034873805 scopus 로고    scopus 로고
    • Biologically motivated quantitative models and the mixture toxicity problem
    • Conolly RB. Biologically motivated quantitative models and the mixture toxicity problem. Toxicological Sciences, 2001; 63(1):1-2.
    • (2001) Toxicological Sciences , vol.63 , Issue.1 , pp. 1-2
    • Conolly, R.B.1
  • 172
    • 23844515740 scopus 로고    scopus 로고
    • Studying toxicants as single chemicals: Does this strategy adequately identify neurotoxic risk
    • Cory-Slechta DA. Studying toxicants as single chemicals: Does this strategy adequately identify neurotoxic risk? Neurotoxicology, 2005; 26(4):491-510.
    • (2005) Neurotoxicology , vol.26 , Issue.4 , pp. 491-510
    • Cory-Slechta, D.A.1
  • 173
    • 81555220943 scopus 로고    scopus 로고
    • Cumulative risk assessment for combined health effects from chemical and nonchemical stressors
    • Sexton K, Linder SH. Cumulative risk assessment for combined health effects from chemical and nonchemical stressors. American Journal of Public Health, 2011; 101:S81-S88.
    • (2011) American Journal of Public Health , vol.101 , pp. S81-S88
    • Sexton, K.1    Linder, S.H.2
  • 174
    • 34548335268 scopus 로고    scopus 로고
    • Initial analyses of the relationship between "thresholds" of toxicity for individual chemicals and "interaction thresholds" for chemical mixtures
    • Yang RS, Dennison JE. Initial analyses of the relationship between "thresholds" of toxicity for individual chemicals and "interaction thresholds" for chemical mixtures. Toxicology and Applied Pharmacology, 2007; 223(2):133-138.
    • (2007) Toxicology and Applied Pharmacology , vol.223 , Issue.2 , pp. 133-138
    • Yang, R.S.1    Dennison, J.E.2
  • 175
    • 0029620727 scopus 로고
    • Utilizing concentration-response data from individual components to detect statistically significant departures from additivity in chemical mixtures
    • Gennings C, Carter WH. Utilizing concentration-response data from individual components to detect statistically significant departures from additivity in chemical mixtures. Biometrics, 1995; 51(4):1264-1277.
    • (1995) Biometrics , vol.51 , Issue.4 , pp. 1264-1277
    • Gennings, C.1    Carter, W.H.2
  • 176
    • 84862302245 scopus 로고    scopus 로고
    • Update on a pharmacokinetic-centric alternative tier II program for MMT-part II: Physiologically based pharmacokinetic modeling and manganese risk assessment
    • Taylor MD, Clewell HJ, 3rd, Andersen ME, Schroeter JD, Yoon M, Keene AM, Dorman DC. Update on a pharmacokinetic-centric alternative tier II program for MMT-part II: Physiologically based pharmacokinetic modeling and manganese risk assessment. Journal of Toxicology, 2012; Article ID 791431, doi:10.1155/2012/791431.
    • (2012) Journal of Toxicology
    • Taylor, M.D.1    Clewell, H.J.2    Andersen, M.E.3    Schroeter, J.D.4    Yoon, M.5    Keene, A.M.6    Dorman, D.C.7
  • 179
    • 41049110206 scopus 로고    scopus 로고
    • Development of a human physiologically based pharmacokinetic (PBPK) model for inorganic arsenic and its mono- and di-methylated metabolites
    • El-Masri HA, Kenyon EM. Development of a human physiologically based pharmacokinetic (PBPK) model for inorganic arsenic and its mono- and di-methylated metabolites. Journal of Pharmacokinetics and Pharmacodynamics, 2008; 35(1):31-68.
    • (2008) Journal of Pharmacokinetics and Pharmacodynamics , vol.35 , Issue.1 , pp. 31-68
    • El-Masri, H.A.1    Kenyon, E.M.2
  • 182
    • 0018095992 scopus 로고
    • A kinetic model of cadmium metabolism in the human being
    • Kjellström T, Nordberg GF. A kinetic model of cadmium metabolism in the human being. Environmental Research, 1978; 16(1-3):248-269.
    • (1978) Environmental Research , vol.16 , Issue.1-3 , pp. 248-269
    • Kjellström, T.1    Nordberg, G.F.2
  • 183
    • 0032847264 scopus 로고    scopus 로고
    • A modeling approach to account for toxicokinetic interactions in the calculation of biological hazard index for chemical mixtures
    • Haddad S, Tardif R, Viau C, Krishnan K. A modeling approach to account for toxicokinetic interactions in the calculation of biological hazard index for chemical mixtures. Toxicology Letters, 1999; 108(2-3):303-308.
    • (1999) Toxicology Letters , vol.108 , Issue.2-3 , pp. 303-308
    • Haddad, S.1    Tardif, R.2    Viau, C.3    Krishnan, K.4
  • 184
    • 0034874732 scopus 로고    scopus 로고
    • A PBPK modeling-based approach to account for interactions in the health risk assessment of chemical mixtures
    • Haddad S, Béliveau M, Tardif R, Krishnan K. A PBPK modeling-based approach to account for interactions in the health risk assessment of chemical mixtures. Toxicological Sciences, 2001; 63(1):125-131.
    • (2001) Toxicological Sciences , vol.63 , Issue.1 , pp. 125-131
    • Haddad, S.1    Béliveau, M.2    Tardif, R.3    Krishnan, K.4
  • 185
    • 84865271285 scopus 로고    scopus 로고
    • Quantitative in vitro to in vivo extrapolation of cell-based toxicity assay results
    • Yoon M, Campbell JL, Andersen ME, Clewell HJ. Quantitative in vitro to in vivo extrapolation of cell-based toxicity assay results. Critical Reviews in Toxicology, 2012; 42(8):633-652.
    • (2012) Critical Reviews in Toxicology , vol.42 , Issue.8 , pp. 633-652
    • Yoon, M.1    Campbell, J.L.2    Andersen, M.E.3    Clewell, H.J.4
  • 188
    • 49249113004 scopus 로고    scopus 로고
    • Development of a high-throughput screening assay for chemical effects on proliferation and viability of immortalized human neural progenitor cells
    • Breier JM, Radio NM, Mundy WR, Shafer TJ. Development of a high-throughput screening assay for chemical effects on proliferation and viability of immortalized human neural progenitor cells. Toxicological Sciences, 2008; 105(1):119-133.
    • (2008) Toxicological Sciences , vol.105 , Issue.1 , pp. 119-133
    • Breier, J.M.1    Radio, N.M.2    Mundy, W.R.3    Shafer, T.J.4


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