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Volumn 108, Issue 2-3, 1999, Pages 303-308

A modeling approach to account for toxicokinetic interactions in the calculation of biological hazard index for chemical mixtures

Author keywords

BEI; BHI; Interactions; Mixtures; PBPK modeling

Indexed keywords

ETHYLBENZENE; TOLUENE; XYLENE;

EID: 0032847264     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-4274(99)00102-2     Document Type: Article
Times cited : (27)

References (11)
  • 1
    • 0344189664 scopus 로고    scopus 로고
    • Threshold limit values for chemical substances and physical agents, and Biological exposure indices
    • ACGIH, Cincinnati, OH
    • ACGIH, 1998. Threshold limit values for chemical substances and physical agents, and Biological exposure indices. American Conference of Governmental Industrial Hygienists, Cincinnati, OH, p. 184.
    • (1998) American Conference of Governmental Industrial Hygienists , pp. 184
  • 2
    • 0021654969 scopus 로고
    • Kinetic considerations in monitoring exposure to chemicals
    • IARC Scientific Publication No. 59
    • Aitio, A., 1984. Kinetic considerations in monitoring exposure to chemicals. In: Monitoring exposure to carcinogenic and mutagenic agents. IARC Scientific Publication No. 59, pp. 127-133.
    • (1984) In: Monitoring Exposure to Carcinogenic and Mutagenic Agents , pp. 127-133
    • Aitio, A.1
  • 3
    • 0032449401 scopus 로고    scopus 로고
    • Physiological modeling of chemical interactions: Implications for mixture risk assessment
    • Haddad S., Krishnan K. Physiological modeling of chemical interactions: implications for mixture risk assessment. Environ. Health Perspect. 106:1998;1377-1384.
    • (1998) Environ. Health Perspect. , vol.106 , pp. 1377-1384
    • Haddad, S.1    Krishnan, K.2
  • 4
    • 0344621315 scopus 로고    scopus 로고
    • An interactions-based physiological toxicokinetic model for chemical mixtures
    • Haddad S., Charest-Tardif G., Tardif R., Krishnan K. An interactions-based physiological toxicokinetic model for chemical mixtures. Toxicologist. 42:1998;341.
    • (1998) Toxicologist , vol.42 , pp. 341
    • Haddad, S.1    Charest-Tardif, G.2    Tardif, R.3    Krishnan, K.4
  • 5
    • 0029781064 scopus 로고    scopus 로고
    • Simulation of toluene in venous blood with a physiologically-based pharmacokinetic model: Its application to biological exposure index development
    • Jang J-Y., Droz P.O. Simulation of toluene in venous blood with a physiologically-based pharmacokinetic model: its application to biological exposure index development. Appl. Occup. Environ. Hyg. 11:1996;1092-1095.
    • (1996) Appl. Occup. Environ. Hyg. , vol.11 , pp. 1092-1095
    • Jang, J.-Y.1    Droz, P.O.2
  • 6
    • 0002252728 scopus 로고
    • Physiologically based pharmacokinetic modeling of chemical mixtures
    • R.S.H. Yang. New York: Academic Press
    • Krishnan K., Andersen M.E., Clewell H.J. III, Yang R.S.H. Physiologically based pharmacokinetic modeling of chemical mixtures. Yang R.S.H. Toxicology of Chemical Mixtures. 1994;399-437 Academic Press, New York.
    • (1994) Toxicology of Chemical Mixtures , pp. 399-437
    • Krishnan, K.1    Andersen, M.E.2    Clewell H.J. III3    Yang, R.S.H.4
  • 7
    • 0026774035 scopus 로고
    • Use of physiologically-based pharmacokinetic models to establish biological exposure indices
    • Leung H-W. Use of physiologically-based pharmacokinetic models to establish biological exposure indices. Am. Ind. Hyg. Assoc. J. 53:1992;369-373.
    • (1992) Am. Ind. Hyg. Assoc. J. , vol.53 , pp. 369-373
    • Leung, H.-W.1
  • 10
    • 0030292269 scopus 로고    scopus 로고
    • Application of physiologically based pharmacokinetic modeling to combination toxicology
    • Simmons J.E. Application of physiologically based pharmacokinetic modeling to combination toxicology. Food Chem. Toxicol. 34:1996;1067-1073.
    • (1996) Food Chem. Toxicol. , vol.34 , pp. 1067-1073
    • Simmons, J.E.1
  • 11
    • 0031149782 scopus 로고    scopus 로고
    • Physiologically-based pharmacokinetic modeling of a ternary mixture of alkyl benzenes in rats and humans
    • Tardif R., Charest-Tardif G., Brodeur J., Krishnan K. Physiologically-based pharmacokinetic modeling of a ternary mixture of alkyl benzenes in rats and humans. Toxicol. Appl. Pharmacol. 144:1997;120-134.
    • (1997) Toxicol. Appl. Pharmacol. , vol.144 , pp. 120-134
    • Tardif, R.1    Charest-Tardif, G.2    Brodeur, J.3    Krishnan, K.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.