메뉴 건너뛰기




Volumn 816, Issue , 2014, Pages 197-234

The role of inflammation in kidney cancer

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; AXITINIB; BEVACIZUMAB; CYCLOOXYGENASE 2 INHIBITOR; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; DENDRITIC CELL VACCINE; EVEROLIMUS; FLUOROURACIL; GAMMA INTERFERON; GEMCITABINE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; IPILIMUMAB; MAMMALIAN TARGET OF RAPAMYCIN INHIBITOR; NONSTEROID ANTIINFLAMMATORY AGENT; PAZOPANIB; PHOSPHOGLYCERATE KINASE; PLACEBO; PROGRAMMED DEATH 1 RECEPTOR; PROTEIN TYROSINE KINASE INHIBITOR; RECOMBINANT INTERLEUKIN 2; RETINOIC ACID; SORAFENIB; SUNITINIB; TEMSIROLIMUS; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA; VASCULOTROPIN RECEPTOR; VINBLASTINE; VON HIPPEL LINDAU PROTEIN; CHEMOKINE RECEPTOR CXCR4; GAMMA INTERFERON INDUCIBLE PROTEIN 10; HYPOXIA INDUCIBLE FACTOR 1; HYPOXIA INDUCIBLE FACTOR 1ALPHA; INTERLEUKIN 6; MATRIX METALLOPROTEINASE 14; STAT PROTEIN; STROMAL CELL DERIVED FACTOR 1; TUMOR NECROSIS FACTOR RECEPTOR 1; TUMOR NECROSIS FACTOR RECEPTOR 2; UNINDEXED DRUG;

EID: 84934438318     PISSN: 00652598     EISSN: 22148019     Source Type: Book Series    
DOI: 10.1007/978-3-348-837-8_9     Document Type: Article
Times cited : (92)

References (223)
  • 2
    • 34447627450 scopus 로고    scopus 로고
    • Effect of the magnitude of lipid lowering on risk of elevated liver enzymes, rhabdomyolysis, and cancer: Insights from large randomized statin trials
    • Alsheikh-Ali AA, Maddukuri PV, Han H, Karas RH (2007) Effect of the magnitude of lipid lowering on risk of elevated liver enzymes, rhabdomyolysis, and cancer: insights from large randomized statin trials. J Am Coll Cardiol 50:409-418
    • (2007) J Am Coll Cardiol , vol.50 , pp. 409-418
    • Alsheikh-Ali, A.A.1    Maddukuri, P.V.2    Han, H.3    Karas, R.H.4
  • 3
    • 45349096041 scopus 로고    scopus 로고
    • American Cancer Society. American Cancer Society, New York
    • American Cancer Society (2008) Cancer facts and figures. American Cancer Society, New York
    • (2008) Cancer Facts and Figures
  • 4
    • 0033135109 scopus 로고    scopus 로고
    • Transforming growth factor be ta1 is a target for the von Hippel-Lindau tumor suppressor and a critical growth factor for clear cell renal carcinoma
    • Ananth S, Knebelmann B, Gruning W, Dhanabal M, Walz G, Stillman IE, Sukhatme VP (1999) Transforming growth factor be ta1 is a target for the von Hippel-Lindau tumor suppressor and a critical growth factor for clear cell renal carcinoma. Cancer Res 59:2210-2216
    • (1999) Cancer Res , vol.59 , pp. 2210-2216
    • Ananth, S.1    Knebelmann, B.2    Gruning, W.3    Dhanabal, M.4    Walz, G.5    Stillman, I.E.6    Sukhatme, V.P.7
  • 5
    • 0033981473 scopus 로고    scopus 로고
    • The plasminogen activation system in tumor growth, invasion, and metastasis
    • Andreasen PA, Egelund R, Petersen HH (2000) The plasminogen activation system in tumor growth, invasion, and metastasis. Cell Mol Life Sci 57:25-40
    • (2000) Cell Mol Life Sci , vol.57 , pp. 25-40
    • Andreasen, P.A.1    Egelund, R.2    Petersen, H.H.3
  • 6
    • 0037441888 scopus 로고    scopus 로고
    • Inhibition of STAT3 signaling induces apoptosis and decreases survivin expression in primary effusion lymphoma
    • Aoki Y Feldman GM Tosato G 2003 Inhibition of STAT3 signaling induces apoptosis and decreases survivin expression in primary effusion lymphoma Blood 101: 1535-1542
    • (2003) Blood , vol.101 , pp. 1535-1542
    • Aoki, Y.1    Feldman, G.M.2    Tosato, G.3
  • 7
    • 3042822267 scopus 로고    scopus 로고
    • Cancer and the chemokine network
    • Balkwill F (2004) Cancer and the chemokine network. Nat Rev Cancer 4:540-550
    • (2004) Nat Rev Cancer , vol.4 , pp. 540-550
    • Balkwill, F.1
  • 10
    • 0033128699 scopus 로고    scopus 로고
    • Reduced expression of the CXCR4 receptor mRNA in hepatocellular carcinoma and lack of inducibility of its ligand alpha-chemokine hIRH/SDF1alpha/PBSF in vitro
    • Begum NA, Shibuta K, Mori M, Barnard GF (1999) Reduced expression of the CXCR4 receptor mRNA in hepatocellular carcinoma and lack of inducibility of its ligand alpha-chemokine hIRH/SDF1alpha/PBSF in vitro. Int J Oncol 14:927-934
    • (1999) Int J Oncol , vol.14 , pp. 927-934
    • Begum, N.A.1    Shibuta, K.2    Mori, M.3    Barnard, G.F.4
  • 12
    • 77956976681 scopus 로고    scopus 로고
    • Macrophage plasticity and interaction with lymphocyte subsets: Cancer as a paradigm
    • Biswas SK, Mantovani A (2010) Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm. Nat Immunol 11:889-896
    • (2010) Nat Immunol , vol.11 , pp. 889-896
    • Biswas, S.K.1    Mantovani, A.2
  • 19
    • 0036554816 scopus 로고    scopus 로고
    • Activated STAT signaling in human tumors provides novel molecular targets for therapeutic intervention
    • Buettner R, Mora LB, Jove R (2002) Activated STAT signaling in human tumors provides novel molecular targets for therapeutic intervention. Clin Cancer Res 8:945-954
    • (2002) Clin Cancer Res , vol.8 , pp. 945-954
    • Buettner, R.1    Mora, L.B.2    Jove, R.3
  • 20
    • 0034648765 scopus 로고    scopus 로고
    • Angiogenesis in cancer and other diseases
    • Carmeliet P, Jain RK (2000) Angiogenesis in cancer and other diseases. Nature 407:249-257
    • (2000) Nature , vol.407 , pp. 249-257
    • Carmeliet, P.1    Jain, R.K.2
  • 22
    • 8644277977 scopus 로고    scopus 로고
    • Impact of cyclooxygenase-2 gene expression on tumor invasiveness in a human renal cell carcinoma cell line
    • Chen Q, Shinohara N, Abe T, Harabayashi T, Nonomura K (2004a ) Impact of cyclooxygenase-2 gene expression on tumor invasiveness in a human renal cell carcinoma cell line. J Urol 172:2153-2157
    • (2004) J Urol , vol.172 , pp. 2153-2157
    • Chen, Q.1    Shinohara, N.2    Abe, T.3    Harabayashi, T.4    Nonomura, K.5
  • 24
    • 0037407573 scopus 로고    scopus 로고
    • Comparisons of outcome and prog nostic features among histologic subtypes of renal cell carcinoma
    • Cheville JC, Lohse CM, Zincke H, Weaver AL, Blute ML (2003) Comparisons of outcome and prog nostic features among histologic subtypes of renal cell carcinoma. Am J Surg Pathol 27:612-624
    • (2003) Am J Surg Pathol , vol.27 , pp. 612-624
    • Cheville, J.C.1    Lohse, C.M.2    Zincke, H.3    Weaver, A.L.4    Blute, M.L.5
  • 27
    • 34547108341 scopus 로고    scopus 로고
    • Clinical factors associated with outcome in patients with metastatic clear-cell renal cell carcinoma treated wit h vascular endothelial growth factortargeted therapy
    • Choueiri TK, Garcia JA, Elson P, Khasawneh M, Usman S, Golshayan AR, Baz RC, Wood L, Rini BI, Bukowski RM (2007) Clinical factors associated with outcome in patients with metastatic clear-cell renal cell carcinoma treated wit h vascular endothelial growth factortargeted therapy. Cancer 110:543-550
    • (2007) Cancer , vol.110 , pp. 543-550
    • Choueiri, T.K.1    Garcia, J.A.2    Elson, P.3    Khasawneh, M.4    Usman, S.5    Golshayan, A.R.6    Baz, R.C.7    Wood, L.8    Rini, B.I.9    Bukowski, R.M.10
  • 28
    • 43249107158 scopus 로고    scopus 로고
    • Tumorderived tumor necrosis factor-alph a promotes progression and epithelial-mesenchymal transition in renal cell carcinoma cells
    • Chuang MJ, Sun KH, Tang SJ, Deng MW, Wu YH, Sung JS, Cha TL, Sun GH (2008) Tumorderived tumor necrosis factor-alph a promotes progression and epithelial-mesenchymal transition in renal cell carcinoma cells. Cancer Sci 99:905-913
    • (2008) Cancer Sci , vol.99 , pp. 905-913
    • Chuang, M.J.1    Sun, K.H.2    Tang, S.J.3    Deng, M.W.4    Wu, Y.H.5    Sung, J.S.6    Cha, T.L.7    Sun, G.H.8
  • 29
    • 70449378635 scopus 로고    scopus 로고
    • The high-dose aldesleukin (IL-2 " select" trial: A trial designed to prospectively validate predictive models of response to high-dose IL-2 treatment in patients with metastatic renal cell carcinoma
    • Clement JM, McDermott DF (2009) The high-dose aldesleukin (IL-2) " select" trial: a trial designed to prospectively validate predictive models of response to high-dose IL-2 treatment in patients with metastatic renal cell carcinoma. Clin Genitourin Cancer 7:E7-E9
    • (2009) Clin Genitourin Cancer , vol.7
    • Clement, J.M.1    McDermott, D.F.2
  • 38
    • 0018121304 scopus 로고
    • The natural history of metastatic renal cell carcinoma: A computer analysis
    • Dekernion JB, Ramming KP, Smith RB (1978) The natural history of metastatic renal cell carcinoma: a computer analysis. J Urol 120:148-152
    • (1978) J Urol , vol.120 , pp. 148-152
    • Dekernion, J.B.1    Ramming, K.P.2    Smith, R.B.3
  • 41
    • 84876990066 scopus 로고    scopus 로고
    • Immunomonitoring and prognostic relevance of neutrophils in clinical trials
    • Do nskov F (2013) Immunomonitoring and prognostic relevance of neutrophils in clinical trials. Semin Cancer Biol 23:200-207
    • (2013) Semin Cancer Biol , vol.23 , pp. 200-207
    • Do Nskov, F.1
  • 42
    • 33646441904 scopus 로고    scopus 로고
    • Impact of immune parameters on long-term survival in metastatic renal cell carcinoma
    • Donskov F, von der Maase H (2006) Impact of immune parameters on long-term survival in metastatic renal cell carcinoma. J Clin Oncol 24:1997-2005
    • (2006) J Clin Oncol , vol.24 , pp. 1997-2005
    • Donskov, F.1    Von Der Maase, H.2
  • 43
    • 0027972253 scopus 로고
    • Tumour necrosis factor-alpha, interleukin-1 be ta and interleukin-6 in patients with renal cell carcinoma
    • Dosquet C, Schaetz A, Faucher C, Lepage E, Wautier JL, Richard F, Cabane J (1994) Tumour necrosis factor-alpha, interleukin-1 be ta and interleukin-6 in patients with renal cell carcinoma. Eur J Cancer 30A:162-167
    • (1994) Eur J Cancer , vol.30 A , pp. 162-167
    • Dosquet, C.1    Schaetz, A.2    Faucher, C.3    Lepage, E.4    Wautier, J.L.5    Richard, F.6    Cabane, J.7
  • 44
    • 84875220714 scopus 로고    scopus 로고
    • Tumorderived macrophage mi gration inhibitory factor promotes an autocrine loop that enhances renal cell carcinoma
    • Du W, Wright BM, Li X, Finke J, Rini BI, Zhou M, He H, Lal P, Welford SM (2013) Tumorderived macrophage mi gration inhibitory factor promotes an autocrine loop that enhances renal cell carcinoma. Oncogene 32:1469-1474
    • (2013) Oncogene , vol.32 , pp. 1469-1474
    • Du, W.1    Wright, B.M.2    Li, X.3    Finke, J.4    Rini, B.I.5    Zhou, M.6    He, H.7    Lal, P.8    Welford, S.M.9
  • 45
    • 0036842215 scopus 로고    scopus 로고
    • Vascular permeability factor/vascular endothelial growth factor: A critical cytokine i n tumor angiogenesis and a potential target for diagnosis and therapy
    • Dvorak HF (2002) Vascular permeability factor/vascular endothelial growth factor: a critical cytokine i n tumor angiogenesis and a potential target for diagnosis and therapy. J Clin Oncol 20:4368-4380
    • (2002) J Clin Oncol , vol.20 , pp. 4368-4380
    • Dvorak, H.F.1
  • 46
    • 0032949884 scopus 로고    scopus 로고
    • Serum concentrations of VEGF and b-FGF in renal cell, prostate and urinary bladder carcinomas
    • Edgren M, Lennernas B, Larsson A, Nilsson S (1999) Serum concentrations of VEGF and b-FGF in renal cell, prostate and urinary bladder carcinomas. Anticancer Res 19:869-873
    • (1999) Anticancer Res , vol.19 , pp. 869-873
    • Edgren, M.1    Lennernas, B.2    Larsson, A.3    Nilsson, S.4
  • 47
    • 0033891377 scopus 로고    scopus 로고
    • Enhanced expression of IFN-gamma mRNA in CD 4(+)or CD8(+)tumour- infiltrating lymphocytes compared to peripheral lymphocytes in patients with renal cell cancer
    • Elsasser-Beile U, Rindsfuser M, Grussenmeyer T, Schultze-Seemann W, Wetterauer U (2000) Enhanced expression of IFN-gamma mRNA in CD 4(+)or CD8(+)tumour-infiltrating lymphocytes compared to peripheral lymphocytes in patients with renal cell cancer. Br J Cancer 83:637-641
    • (2000) Br J Cancer , vol.83 , pp. 637-641
    • Elsasser-Beile, U.1    Rindsfuser, M.2    Grussenmeyer, T.3    Schultze-Seemann, W.4    Wetterauer, U.5
  • 48
    • 0035476509 scopus 로고    scopus 로고
    • Induction of hypervascularity without leakage or inflammation in transgenic mice overexpressing hypoxia-inducible factor-1alpha
    • Elson DA, Thurston G, Huang LE, Ginzinger DG, McDonald DM, Johns on RS, Arbeit JM (2001) Induction of hypervascularity without leakage or inflammation in transgenic mice overexpressing hypoxia-inducible factor-1alpha. Genes Dev 15:2520-2532
    • (2001) Genes Dev , vol.15 , pp. 2520-2532
    • Elson, D.A.1    Thurston, G.2    Huang, L.E.3    Ginzinger, D.G.4    McDonald, D.M.5    Johns On, R.S.6    Arbeit, J.M.7
  • 49
    • 76749147303 scopus 로고    scopus 로고
    • Chemo-immun otherapy in RCC: The end of a story
    • Escudier B (2010) Chemo-immun otherapy in RCC: the end of a story. Lancet 375:613-614
    • (2010) Lancet , vol.375 , pp. 613-614
    • Escudier, B.1
  • 50
    • 33745819269 scopus 로고    scopus 로고
    • Formation of primary cilia in the renal epithelium is regulated by the von Hippel-Lindau tumor s uppressor protein
    • Esteban MA Harten SK Tran MG Maxwell PH 2006) Formation of primary cilia in the renal epithelium is regulated by the von Hippel-Lindau tumor s uppressor protein J Am Soc Nephrol 17: 1801-1806
    • (2006) J Am Soc Nephrol , vol.17 , pp. 1801-1806
    • Esteban, M.A.1    Harten, S.K.2    Tran, M.G.3    Maxwell, P.H.4
  • 52
    • 84857506147 scopus 로고    scopus 로고
    • Consequence of dose scheduling of sunitinib on host immune response elements and vaccine combination therapy
    • Farsaci B, Higgins JP, Hodge JW (2012) Consequence of dose scheduling of sunitinib on host immune response elements and vaccine combination therapy. Int J Cancer 130:1948-1959
    • (2012) Int J Cancer , vol.130 , pp. 1948-1959
    • Farsaci, B.1    Higgins, J.P.2    Hodge, J.W.3
  • 58
    • 0025805026 scopus 로고
    • Recombinant interleukin-2 and lymphokine-activated kille r cells in renal cancer patients: II Characterization of cells cultured ex vivo and their contribution to the in vivo immunomodulation
    • Fortis C, Ferrero E, Biffi M, Heltai S, Besana C, Bucci E, Tresoldi M, Rugarli C (1991) Recombinant interleukin-2 and lymphokine-activated kille r cells in renal cancer patients: II. Characterization of cells cultured ex vivo and their contribution to the in vivo immunomodulation. Cancer Immunol Immunother 33:128-132
    • (1991) Cancer Immunol Immunother , vol.33 , pp. 128-132
    • Fortis, C.1    Ferrero, E.2    Biffi, M.3    Heltai, S.4    Besana, C.5    Bucci, E.6    Tresoldi, M.7    Rugarli, C.8
  • 59
    • 0021182188 scopus 로고
    • Behaviour of protein C inhibitor in intravascular coagulation and liver disease
    • Francis RB Jr, Thomas W (1984) Behaviour of protein C inhibitor in intravascular coagulation and liver disease. Thromb Haemost 52:71-74
    • (1984) Thromb Haemost , vol.52 , pp. 71-74
    • Francis Jr., R.B.1    Thomas, W.2
  • 61
    • 80155184068 scopus 로고    scopus 로고
    • Generation of a mouse model of von Hippel-Lindau kidney disease leading to renal can cers by expression of a constitutively active mutant of HIF1alpha
    • Fu L, Wang G, Shevchuk MM, Nanus DM, Gudas LJ (2011) Generation of a mouse model of von Hippel-Lindau kidney disease leading to renal can cers by expression of a constitutively active mutant of HIF1alpha. Cancer Res 71:6848-6856
    • (2011) Cancer Res , vol.71 , pp. 6848-6856
    • Fu, L.1    Wang, G.2    Shevchuk, M.M.3    Nanus, D.M.4    Gudas, L.J.5
  • 62
    • 60849093525 scopus 로고    scopus 로고
    • Cyclooxygenase-2 (COX-2) in carcinogenesis and sele ctive COX-2 inhibitors for chemoprevention in gastrointestinal cancers
    • Fujimura T, Ohta T, Oyama K, Miyashita T, Miwa K (2007) Cyclooxygenase-2 (COX-2) in carcinogenesis and sele ctive COX-2 inhibitors for chemoprevention in gastrointestinal cancers. J Gastrointest Cancer 38:78-82
    • (2007) J Gastrointest Cancer , vol.38 , pp. 78-82
    • Fujimura, T.1    Ohta, T.2    Oyama, K.3    Miyashita, T.4    Miwa, K.5
  • 63
    • 10244279184 scopus 로고    scopus 로고
    • Mechanisms and functional significance of tumour-induced dendritic-cell defects
    • Gabrilovich D (2004) Mechanisms and functional significance of tumour-induced dendritic-cell defects. Nat Rev Immunol 4:941-952
    • (2004) Nat Rev Immunol , vol.4 , pp. 941-952
    • Gabrilovich, D.1
  • 66
    • 0030589313 scopus 로고    scopus 로고
    • Human monocyte chemoattractant protein (MCP)-4 is a novel CC chemokine with activities on monocytes, eosinophils, and basophils induced in allergic and nonallergic inflammation that signals through the CC chemokine receptors (CCR)-2 and-3
    • Garcia-Zepeda EA, Combadiere C, Rothenberg ME, Sarafi MN, Lavigne F, Hamid Q, Murphy PM, Luster AD (1996a ) Human monocyte chemoattractant protein (MCP)-4 is a novel CC chemokine with activities on monocytes, eosinophils, and basophils induced in allergic and nonallergic inflammation that signals through the CC chemokine receptors (CCR)-2 and-3. J I mmunol 157:5613-5626
    • (1996) J i Mmunol , vol.157 , pp. 5613-5626
    • Garcia-Zepeda, E.A.1    Combadiere, C.2    Rothenberg, M.E.3    Sarafi, M.N.4    Lavigne, F.5    Hamid, Q.6    Murphy, P.M.7    Luster, A.D.8
  • 67
    • 0029944290 scopus 로고    scopus 로고
    • Human eotaxin is a specific chemoattractant for eosinophil cells and provides a new mechanism to explain tissue eosinophilia
    • Garcia-Zepeda EA, Rothenberg ME, Ownbey RT, Celestin J, Leder P, Luster AD (1996b ) Human eotaxin is a specific chemoattractant for eosinophil cells and provides a new mechanism to explain tissue eosinophilia. Nat Med 2:449-456
    • (1996) Nat Med , vol.2 , pp. 449-456
    • Garcia-Zepeda, E.A.1    Rothenberg, M.E.2    Ownbey, R.T.3    Celestin, J.4    Leder, P.5    Luster, A.D.6
  • 71
    • 0035852668 scopus 로고    scopus 로고
    • Vascular tumors in livers with targeted inactivation of the von Hippel-Lindau tumor suppressor
    • Haase VH Glickman JN Socolovsky M Jaenisch R 2001) Vascular tumors in livers with targeted inactivation of the von Hippel-Lindau tumor suppressor Proc Natl Acad Sci USA 98: 1583-1588
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 1583-1588
    • Haase, V.H.1    Glickman, J.N.2    Socolovsky, M.3    Jaenisch, R.4
  • 72
    • 77951679822 scopus 로고    scopus 로고
    • Advanced malignant melanoma: Immunologic and multimodal therapeutic strategies
    • Halama N, Zoernig I, Jaeger D (2010) Advanced malignant melanoma: immunologic and multimodal therapeutic strategies. J Oncol 2010:689893
    • (2010) J Oncol , vol.2010 , pp. 689893
    • Halama, N.1    Zoernig, I.2    Jaeger, D.3
  • 73
    • 70249140303 scopus 로고    scopus 로고
    • Myeloid-derived suppressor cells down-regulate L-selectin expression on CD4+ and CD8+ T cells
    • Hanson EM, Clements VK, Sinha P, Ilkovitch D, Ostrand-Rosenberg S (2009) Myeloid-derived suppressor cells down-regulate L-selectin expression on CD4+ and CD8+ T cells. J Immunol 183:937-944
    • (2009) J Immunol , vol.183 , pp. 937-944
    • Hanson, E.M.1    Clements, V.K.2    Sinha, P.3    Ilkovitch, D.4    Ostrand-Rosenberg, S.5
  • 75
    • 6944246036 scopus 로고    scopus 로고
    • The balance between MMP-2/-9 and TIMP-1/-2 is shifted towards MMP in renal cell carcinomas and can be further disturbed by hydrogen peroxide
    • Hemmerlein B, Johanns U, Halbfass J, Bottcher T, Heuser M, Radzun HJ, Thelen P (2004) The balance between MMP-2/-9 and TIMP-1/-2 is shifted towards MMP in renal cell carcinomas and can be further disturbed by hydrogen peroxide. Int J Oncol 24:1069-1076
    • (2004) Int J Oncol , vol.24 , pp. 1069-1076
    • Hemmerlein, B.1    Johanns, U.2    Halbfass, J.3    Bottcher, T.4    Heuser, M.5    Radzun, H.J.6    Thelen, P.7
  • 76
    • 84865284454 scopus 로고    scopus 로고
    • TNF-alpha induces epithelial-mesenchymal transition of renal cell carcin oma cells via a GSK3beta-dependent mechanism
    • Ho MY, Tang SJ, Chuang MJ, Cha TL, Li JY, Sun GH, Sun KH (2012) TNF-alpha induces epithelial-mesenchymal transition of renal cell carcin oma cells via a GSK3beta-dependent mechanism. Mol Cancer Res 10:1109-1119
    • (2012) Mol Cancer Res , vol.10 , pp. 1109-1119
    • Ho, M.Y.1    Tang, S.J.2    Chuang, M.J.3    Cha, T.L.4    Li, J.Y.5    Sun, G.H.6    Sun, K.H.7
  • 77
    • 0036075424 scopus 로고    scopus 로고
    • Activation of signal transducer and activator of trans cription 3 in renal cell carcinoma: A study of incidence and its association with pathological features and clinical outcome
    • Horiguchi A, Oya M, Shimada T, Uchida A, Marumo K, Murai M (2002) Activation of signal transducer and activator of trans cription 3 in renal cell carcinoma: a study of incidence and its association with pathological features and clinical outcome. J Urol 168:762-765
    • (2002) J Urol , vol.168 , pp. 762-765
    • Horiguchi, A.1    Oya, M.2    Shimada, T.3    Uchida, A.4    Marumo, K.5    Murai, M.6
  • 78
    • 11144238571 scopus 로고    scopus 로고
    • 3-hydroxy-3-methylglutaryl-coenzyme a reductase inhibitor, fluvastatin, as a novel agent for prophylaxis of renal cancer metastasis
    • Horiguchi A, Sumitomo M, Asakuma J, Asano T, Asano T, Haya kawa M (2004) 3-hydroxy-3-methylglutaryl-coenzyme a reductase inhibitor, fluvastatin, as a novel agent for prophylaxis of renal cancer metastasis. Clin Cancer Res 10:8648-8655
    • (2004) Clin Cancer Res , vol.10 , pp. 8648-8655
    • Horiguchi, A.1    Sumitomo, M.2    Asakuma, J.3    Asano, T.4    Asano, T.5    Haya Kawa, M.6
  • 80
    • 31544446571 scopus 로고    scopus 로고
    • Gr-1+CD115+ immature myeloid suppressor cells mediate the development of tumor-induced T regulatory cells and T-cell anergy in tumor-bearing host
    • Huang B, Pan PY, Li Q, Sato AI, Levy DE, Brombe rg J, Divino CM, Chen SH (2006) Gr-1+CD115+ immature myeloid suppressor cells mediate the development of tumor-induced T regulatory cells and T-cell anergy in tumor-bearing host. Cancer Res 66:1123-1131
    • (2006) Cancer Res , vol.66 , pp. 1123-1131
    • Huang, B.1    Pan, P.Y.2    Li, Q.3    Sato, A.I.4    Levy, D.E.5    Brombe Rg, J.6    Divino, C.M.7    Chen, S.H.8
  • 85
    • 70350455089 scopus 로고    scopus 로고
    • Presence of intratumoral neutrophils is an independent prognostic factor in localized renal cell carcinoma
    • Jensen HK, Donskov F, Marcussen N, Nordsmark M, Lundbeck F, von der Maase H (2009) Presence of intratumoral neutrophils is an independent prognostic factor in localized renal cell carcinoma. J Clin Oncol 27:4709-4717
    • (2009) J Clin Oncol , vol.27 , pp. 4709-4717
    • Jensen, H.K.1    Donskov, F.2    Marcussen, N.3    Nordsmark, M.4    Lundbeck, F.5    Von Der Maase, H.6
  • 86
    • 0027947371 scopus 로고
    • Molecular cloning of TPAR1, a gene whose expression is repressed by the tumor promoter 12-O-tetradecanoylphorbol 13-acetate (TPA
    • Jiang W, Zhou P, Kahn SM, Tomita N, Johnson MD, Weinstein IB (1994) Molecular cloning of TPAR1, a gene whose expression is repressed by the tumor promoter 12-O-tetradecanoylphorbol 13-acetate (TPA). Exp Cell Res 215:284-293
    • (1994) Exp Cell Res , vol.215 , pp. 284-293
    • Jiang, W.1    Zhou, P.2    Kahn, S.M.3    Tomita, N.4    Johnson, M.D.5    Weinstein, I.B.6
  • 88
    • 65949112237 scopus 로고    scopus 로고
    • Treatment of kidney cancer: Insights provided by the VHL tumor-suppressor protein
    • Kaelin WG Jr (2009) Treatment of kidney cancer: insights provided by the VHL tumor-suppressor protein. Cancer 115:2262-2272
    • (2009) Cancer , vol.115 , pp. 2262-2272
    • Kaelin Jr., W.G.1
  • 89
    • 0034798212 scopus 로고    scopus 로고
    • Increased expression of matrix metalloproteinases 2 and 9 and tissue inhibitors of metalloproteinases 1 and 2 correlate with poor prognostic variables in renal cell carcinoma
    • Kallakury BV, Karikehalli S, Haholu A, Sheehan CE, Azumi N, Ross JS (2001) Increased expression of matrix metalloproteinases 2 and 9 and tissue inhibitors of metalloproteinases 1 and 2 correlate with poor prognostic variables in renal cell carcinoma. Clin Cancer Res 7:3113-3119
    • (2001) Clin Cancer Res , vol.7 , pp. 3113-3119
    • Kallakury, B.V.1    Karikehalli, S.2    Haholu, A.3    Sheehan, C.E.4    Azumi, N.5    Ross, J.S.6
  • 91
    • 79952280562 scopus 로고    scopus 로고
    • Development and characterization of clinically relevant tumor models from patients with renal cell ca rcinoma
    • Karam JA, Zhang XY, Tamboli P, Margulis V, Wang H, Abel EJ, Culp SH, Wood CG (2011) Development and characterization of clinically relevant tumor models from patients with renal cell ca rcinoma. Eur Urol 59:619-628
    • (2011) Eur Urol , vol.59 , pp. 619-628
    • Karam, J.A.1    Zhang, X.Y.2    Tamboli, P.3    Margulis, V.4    Wang, H.5    Abel, E.J.6    Culp, S.H.7    Wood, C.G.8
  • 92
    • 38649103121 scopus 로고    scopus 로고
    • Statins might reduce risk of renal cell carcinoma in humans: Case-control study of 500,000 veterans
    • Khurana V, Caldito G, Ankem M (2008) Statins might reduce risk of renal cell carcinoma in humans: case-control study of 500,000 veterans. Urology 71:118-122
    • (2008) Urology , vol.71 , pp. 118-122
    • Khurana, V.1    Caldito, G.2    Ankem, M.3
  • 93
    • 1542399554 scopus 로고    scopus 로고
    • Susceptibility to vascular neoplasms but no increased susceptibility to renal carcinogenesis in Vhl knockout mice
    • Kleymenova E, Everitt JI, Pluta L, Portis M, Gnarra JR, Walker CL (2004) Susceptibility to vascular neoplasms but no increased susceptibility to renal carcinogenesis in Vhl knockout mice. Carcinogenesis 2 5:309-315
    • (2004) Carcinogenesis , vol.25 , pp. 309-315
    • Kleymenova, E.1    Everitt, J.I.2    Pluta, L.3    Portis, M.4    Gnarra, J.R.5    Walker, C.L.6
  • 95
    • 77951754469 scopus 로고    scopus 로고
    • Direct and differential suppression of myeloid-derived suppressor cell subsets by sunitinib is compartmentally constrained
    • Ko JS, Rayman P, Ireland J, Swaidani S, Li G, Bunting KD, Rini B, Finke JH, Cohen PA (2010) Direct and differential suppression of myeloid-derived suppressor cell subsets by sunitinib is compartmentally constrained. Cancer Res 70:3526-3536
    • (2010) Cancer Res , vol.70 , pp. 3526-3536
    • Ko, J.S.1    Rayman, P.2    Ireland, J.3    Swaidani, S.4    Li, G.5    Bunting, K.D.6    Rini, B.7    Finke, J.H.8    Cohen, P.A.9
  • 97
    • 79959228665 scopus 로고    scopus 로고
    • Macrophage infiltration and its prognostic relevance in clear cell renal cell carcinoma
    • Komohara Y, Hasita H, Ohnishi K, Fujiwara Y, Suzu S, Eto M, Takeya M (2011) Macrophage infiltration and its prognostic relevance in clear cell renal cell carcinoma. Cancer Sci 102:1424-1431
    • (2011) Cancer Sci , vol.102 , pp. 1424-1431
    • Komohara, Y.1    Hasita, H.2    Ohnishi, K.3    Fujiwara, Y.4    Suzu, S.5    Eto, M.6    Takeya, M.7
  • 98
    • 33745587776 scopus 로고    scopus 로고
    • Favorable prognosis of renal cell carcinoma with increased expression of chemokines associated with a Th1-type immune response
    • Kondo T, Nakazawa H, Ito F, Hashimoto Y, Osa ka Y, Futatsuyama K, Toma H, Tanabe K (2006) Favorable prognosis of renal cell carcinoma with increased expression of chemokines associated with a Th1-type immune response. Cancer Sci 97:780-786
    • (2006) Cancer Sci , vol.97 , pp. 780-786
    • Kondo, T.1    Nakazawa, H.2    Ito, F.3    Hashimoto, Y.4    Osa Ka, Y.5    Futatsuyama, K.6    Toma, H.7    Tanabe, K.8
  • 99
    • 0345109257 scopus 로고    scopus 로고
    • Expression of metalloproteinase 2 and 9 and their inhibitors in renal cell carcinoma
    • Kugler A, Hemmerlein B, Thelen P, Kallerhoff M, Radzun HJ, Ringert RH (1998) Expression of metalloproteinase 2 and 9 and their inhibitors in renal cell carcinoma. J Urol 160:1914-1918
    • (1998) J Urol , vol.160 , pp. 1914-1918
    • Kugler, A.1    Hemmerlein, B.2    Thelen, P.3    Kallerhoff, M.4    Radzun, H.J.5    Ringert, R.H.6
  • 103
    • 0026654795 scopus 로고
    • Protein C inhibitor in human body fluids. Seminal plasma is rich in inhibitor antigen deriving from cells throughout the male reproductive system
    • Laurell M, Christensson A, Abrahamsson PA, Stenflo J, Lilja H (1992) Protein C inhibitor in human body fluids. Seminal plasma is rich in inhibitor antigen deriving from cells throughout the male reproductive system. J Clin Invest 89:1094-1101
    • (1992) J Clin Invest , vol.89 , pp. 1094-1101
    • Laurell, M.1    Christensson, A.2    Abrahamsson, P.A.3    Stenflo, J.4    Lilja, H.5
  • 104
    • 0029090362 scopus 로고
    • Phase III randomized trial of interleukin-2 with or without lymphokine-activated killer cells in the treatment of patients with advanced renal cell carcinoma
    • Law TM, Motzer RJ, Mazumdar M, Sell KW, Walther PJ, O'Connell M, Khan A, Vlamis V, Vogelzang NJ, Bajorin DF (1995) Phase III randomized trial of interleukin-2 with or without lymphokine-activated killer cells in the treatment of patients with advanced renal cell carcinoma. Cancer 76:824-832
    • (1995) Cancer , vol.76 , pp. 824-832
    • Law, T.M.1    Motzer, R.J.2    Mazumdar, M.3    Sell, K.W.4    Walther, P.J.5    O'Connell, M.6    Khan, A.7    Vlamis, V.8    Vogelzang, N.J.9    Bajorin, D.F.10
  • 105
    • 0036468287 scopus 로고    scopus 로고
    • Cyclooxygenase-2 inhibition by celecoxib reduces proliferation and induces apoptosis in angiogenic endothelial cells in vivo
    • Leahy KM, Ornberg RL, Wang Y, Zweifel B S, Koki AT, Masferrer JL (2002) Cyclooxygenase-2 inhibition by celecoxib reduces proliferation and induces apoptosis in angiogenic endothelial cells in vivo. Cancer Res 62:625-631
    • (2002) Cancer Res , vol.62 , pp. 625-631
    • Leahy, K.M.1    Ornberg, R.L.2    Wang, Y.3    Zweifel, B.S.4    Koki, A.T.5    Masferrer, J.L.6
  • 107
    • 79960378039 scopus 로고    scopus 로고
    • New insights into the biology of renal cell carcinoma
    • Li L, Kaelin WG J r (2011) New insights into the biology of renal cell carcinoma. Hematol Oncol Clin North Am 25:667-686
    • (2011) Hematol Oncol Clin North Am , vol.25 , pp. 667-686
    • Li, L.1    Kaelin Jr., W.G.2
  • 108
    • 72049105867 scopus 로고    scopus 로고
    • The role of the mammalian target of rapamycin (mTOR) in renal disease
    • Lieberthal W, Levine JS (2009) The role of the mammalian target of rapamycin (mTOR) in renal disease. J Am Soc Nephrol 20:2493-2502
    • (2009) J Am Soc Nephrol , vol.20 , pp. 2493-2502
    • Lieberthal, W.1    Levine, J.S.2
  • 111
    • 84876156177 scopus 로고    scopus 로고
    • Neutrophil chemokines secreted by tumor cells mount a lung antimetastatic response during r enal cell carcinoma progression
    • Lopez-Lago MA, Posner S, Thodima VJ, Molina AM, Motzer RJ, Chaganti RS (2013) Neutrophil chemokines secreted by tumor cells mount a lung antimetastatic response during r enal cell carcinoma progression. Oncogene 32:1752-1760
    • (2013) Oncogene , vol.32 , pp. 1752-1760
    • Lopez-Lago, M.A.1    Posner, S.2    Thodima, V.J.3    Molina, A.M.4    Motzer, R.J.5    Chaganti, R.S.6
  • 112
    • 57349143530 scopus 로고    scopus 로고
    • Glycogen synthase kinase 3beta (GSK3beta) in tumorigenesis and cancer chemotherapy
    • Luo J (2009) Glycogen synthase kinase 3beta (GSK3beta) in tumorigenesis and cancer chemotherapy. Cancer Lett 273:194-200
    • (2009) Cancer Lett , vol.273 , pp. 194-200
    • Luo, J.1
  • 113
    • 33746886185 scopus 로고    scopus 로고
    • Primary cilium formation requires von hippel-lindau gene function in renal-derived cells
    • Lutz MS, Burk RD (2006) Primary cilium formation requires von hippel-lindau gene function in renal-derived cells. Cancer Res 66:6903-6907
    • (2006) Cancer Res , vol.66 , pp. 6903-6907
    • Lutz, M.S.1    Burk, R.D.2
  • 114
    • 79956317112 scopus 로고    scopus 로고
    • Von Hippel-Lindau disease: A clinical and scientific review
    • Maher ER Neumann HP Richard S (2011) von Hippel-Lindau disease: a clinical and scientific review Eur J Hum Genet 19: 617-623
    • (2011) Eur J Hum Genet , vol.19 , pp. 617-623
    • Maher, E.R.1    Neumann, H.P.2    Richard, S.3
  • 117
    • 34247200050 scopus 로고    scopus 로고
    • Immunotherapy for metastatic renal cell carcinoma
    • McDermott DF, Rini BI (2007) Immunotherapy for metastatic renal cell carcinoma. BJU Int 99:1282-1288
    • (2007) BJU Int , vol.99 , pp. 1282-1288
    • McDermott, D.F.1    Rini, B.I.2
  • 121
    • 84883183676 scopus 로고    scopus 로고
    • Predictive markers in advanced renal cell carcinoma
    • Michaelson MD, Stadler WM (2013) Predictive markers in advanced renal cell carcinoma. Semin Oncol 40:459-464
    • (2013) Semin Oncol , vol.40 , pp. 459-464
    • Michaelson, M.D.1    Stadler, W.M.2
  • 122
    • 0019219923 scopus 로고
    • Indications for and results of nephrectomy for metastatic renal cell carcinoma
    • Middleton AW Jr (1980) Indications for and results of nephrectomy for metastatic renal cell carcinoma. Urol Clin North Am 7:711-717
    • (1980) Urol Clin North Am , vol.7 , pp. 711-717
    • Middleton Jr., A.W.1
  • 124
    • 0031907078 scopus 로고    scopus 로고
    • IL-4 induces eotaxin: A possible mechanism of selective eosinophil recruitment in helminth infection an d atopy
    • Mochizuki M, Bartels J, Mallet AI, Christophers E, Schroder JM (1998) IL-4 induces eotaxin: a possible mechanism of selective eosinophil recruitment in helminth infection an d atopy. J Immunol 160:60-68
    • (1998) J Immunol , vol.160 , pp. 60-68
    • Mochizuki, M.1    Bartels, J.2    Mallet, A.I.3    Christophers, E.4    Schroder, J.M.5
  • 125
    • 80655128601 scopus 로고    scopus 로고
    • The colony-stimulating factor-1 (CSF-1) receptor sustains ERK1/2 activation and proliferation in breast cancer c ell lines
    • Morandi A, Barbetti V, Riverso M, Sbarba PD, Rovida E (2011) The colony-stimulating factor-1 (CSF-1) receptor sustains ERK1/2 activation and proliferation in breast cancer c ell lines. PLoS ONE 6:e27450
    • (2011) PLoS ONE , vol.6
    • Morandi, A.1    Barbetti, V.2    Riverso, M.3    Sbarba, P.D.4    Rovida, E.5
  • 126
    • 56749174940 scopus 로고    scopus 로고
    • Exploring the full spectrum of macrophage activation
    • Mosser DM, Edwards JP (2008) Exploring the full spectrum of macrophage activation. Nat Rev Immunol 8:958-969
    • (2008) Nat Rev Immunol , vol.8 , pp. 958-969
    • Mosser, D.M.1    Edwards, J.P.2
  • 134
    • 84880948301 scopus 로고    scopus 로고
    • Clinical perspectives on targeting of myeloid derived suppressor cells in the treatment of cancer
    • Najjar YG, Finke JH (2013) Clinical perspectives on targeting of myeloid derived suppressor cells in the treatment of cancer. Front Oncol 3:49
    • (2013) Front Oncol , vol.3 , pp. 49
    • Najjar, Y.G.1    Finke, J.H.2
  • 135
    • 0036739439 scopus 로고    scopus 로고
    • Prognostic factors of survival and rapid progression in 782 patients with metastatic renal carcinomas treated by cy tokines: A report from the Groupe Francais d'Immunotherapie
    • Negr ier S Escudier B Gomez F Douillard JY Ravaud A Chevreau C Buclon M Perol D Lasset C 2002 Prognostic factors of survival and rapid progression in 782 patients with metastatic renal carcinomas treated by cy tokines: a report from the Groupe Francais d'Immunotherapie Ann Oncol1 13: 1460-1468
    • (2002) Ann Oncol , vol.13 , pp. 1460-1468
    • Negr Ier, S.1    Escudier, B.2    Gomez, F.3    Douillard, J.Y.4    Ravaud, A.5    Chevreau, C.6    Buclon, M.7    Perol, D.8    Lasset, C.9
  • 136
    • 0022626209 scopus 로고
    • Interferon therapy for the treatment of renal cancer
    • Neidhart JA (1986) Interferon therapy for the treatment of renal cancer. Cancer 57:1696-1699
    • (1986) Cancer , vol.57 , pp. 1696-1699
    • Neidhart, J.A.1
  • 139
    • 0035941291 scopus 로고    scopus 로고
    • The von Hippel-Lindau tumor suppressor protein mediates ubiquitination of activated atypical protein kinase C
    • Okuda H, Saitoh K, Hirai S, Iwai K, Takaki Y, Baba M, Minato N, Ohno S, Shuin T (2001) The von Hippel-Lindau tumor suppressor protein mediates ubiquitination of activated atypical protein kinase C. J Biol Chem 276:43 611-43617
    • (2001) J Biol Chem , vol.276 , pp. 43611-43617
    • Okuda, H.1    Saitoh, K.2    Hirai, S.3    Iwai, K.4    Takaki, Y.5    Baba, M.6    Minato, N.7    Ohno, S.8    Shuin, T.9
  • 141
    • 0035963273 scopus 로고    scopus 로고
    • Constitutive activation of nuclear factor-kappaB prevents TRAIL-induced apoptosis in renal cancer cells
    • Oya M, Ohtsubo M, Takayanagi A, Tachibana M, Shimizu N, Murai M (2001) Constitutive activation of nuclear factor-kappaB prevents TRAIL-induced apoptosis in renal cancer cells. Oncogene 20:3888-3896
    • (2001) Oncogene , vol.20 , pp. 3888-3896
    • Oya, M.1    Ohtsubo, M.2    Takayanagi, A.3    Tachibana, M.4    Shimizu, N.5    Murai, M.6
  • 142
    • 65549141834 scopus 로고    scopus 로고
    • The novel role of tyrosine kinase inhibitor in the reversal of immune suppression and modulation of tumor microenvironment fo r immune-based cancer therapies
    • Ozao-Choy J, Ma G, Kao J, Wang GX, Meseck M, Sung M, Schwartz M, Divino CM, Pan PY, Chen SH (2009) The novel role of tyrosine kinase inhibitor in the reversal of immune suppression and modulation of tumor microenvironment fo r immune-based cancer therapies. Cancer Res 69:2514-2522
    • (2009) Cancer Res , vol.69 , pp. 2514-2522
    • Ozao-Choy, J.1    Ma, G.2    Kao, J.3    Wang, G.X.4    Meseck, M.5    Sung, M.6    Schwartz, M.7    Divino, C.M.8    Pan, P.Y.9    Chen, S.H.10
  • 143
    • 75149179545 scopus 로고    scopus 로고
    • Immune stimulatory receptor CD40 is required for T-cell suppression and T regulatory cell activation mediated by myeloid-derived suppressor cells in cancer
    • Pan PY, Ma G, Weber KJ, Ozao-Choy J, Wang G, Yin B, Divino CM, Chen SH (2010) Immune stimulatory receptor CD40 is required for T-cell suppression and T regulatory cell activation mediated by myeloid-derived suppressor cells in cancer. Cancer Res 70:99-108
    • (2010) Cancer Res , vol.70 , pp. 99-108
    • Pan, P.Y.1    Ma, G.2    Weber, K.J.3    Ozao-Choy, J.4    Wang, G.5    Yin, B.6    Divino, C.M.7    Chen, S.H.8
  • 145
    • 84858766182 scopus 로고    scopus 로고
    • The blockade of immune checkpoints in cancer immunotherapy
    • Pardoll D M (2012) The blockade of immune checkpoints in cancer immunotherapy. Nat Rev Cancer 12:252-264
    • (2012) Nat Rev Cancer , vol.12 , pp. 252-264
    • Pardoll, D.M.1
  • 146
    • 0032477788 scopus 로고    scopus 로고
    • The von Hippel-Lindau tumor suppressor gene is require d for cell cycle exit upon serum withdrawal
    • Pause A, Lee S, Lonergan KM, Klausner RD (1998) The von Hippel-Lindau tumor suppressor gene is require d for cell cycle exit upon serum withdrawal. Proc Natl Acad Sci USA 95:993-998
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 993-998
    • Pause, A.1    Lee, S.2    Lonergan, K.M.3    Klausner, R.D.4
  • 147
    • 68149155982 scopus 로고    scopus 로고
    • Blockade of CTLA-4 on both effector and regulatory T ce ll compartments contributes to the antitumor activity of anti-CTLA-4 antibodies
    • Peggs KS, Quezada SA, Chambers CA, Korman AJ, Allison JP (2009) Blockade of CTLA-4 on both effector and regulatory T ce ll compartments contributes to the antitumor activity of anti-CTLA-4 antibodies. J Exp Med 206:1717-1725
    • (2009) J Exp Med , vol.206 , pp. 1717-1725
    • Peggs, K.S.1    Quezada, S.A.2    Chambers, C.A.3    Korman, A.J.4    Allison, J.P.5
  • 149
    • 33846675525 scopus 로고    scopus 로고
    • Tumor cell invasion of von Hippel Lindau renal cell carcinoma cells is mediated by membrane type-1 matrix metalloproteinase
    • Petrella BL, Brinckerhoff CE (2006) Tumor cell invasion of von Hippel Lindau renal cell carcinoma cells is mediated by membrane type-1 matrix metalloproteinase. Mol Cancer 5:66
    • (2006) Mol Cancer , vol.5 , pp. 66
    • Petrella, B.L.1    Brinckerhoff, C.E.2
  • 150
    • 13944252559 scopus 로고    scopus 로고
    • Identification of membrane type-1 matrix metalloproteinase as a target of hypoxia-inducible factor-2 alpha in von Hippel-Lindau renal cell carcinoma
    • Petrella BL, Lohi J, Brinckerhoff CE (2005) Identification of membrane type-1 matrix metalloproteinase as a target of hypoxia-inducible factor-2 alpha in von Hippel-Lindau renal cell carcinoma. Oncogene 24:1043-1052
    • (2005) Oncogene , vol.24 , pp. 1043-1052
    • Petrella, B.L.1    Lohi, J.2    Brinckerhoff, C.E.3
  • 151
    • 0242694963 scopus 로고    scopus 로고
    • The von Hippel-Lindau tumor suppressor protei n sensitizes renal cell carcinoma cells to tumor necrosis factor-induced cytotoxicity by suppressing the nuclear factorkappaB-dependent antiapoptotic pathway
    • Qi H, Ohh M (2003) The von Hippel-Lindau tumor suppressor protei n sensitizes renal cell carcinoma cells to tumor necrosis factor-induced cytotoxicity by suppressing the nuclear factorkappaB-dependent antiapoptotic pathway. Cancer Res 63:7076-7080
    • (2003) Cancer Res , vol.63 , pp. 7076-7080
    • Qi, H.1    Ohh, M.2
  • 152
    • 0037872265 scopus 로고    scopus 로고
    • Apoptosis induction in renal cell carcinoma by TRAIL and gamma-radiation is impaired by deficient caspase-9 cleavage
    • Ramp U, Caliskan E, Mahotka C, Krieg A, Heikaus S, Gabbert HE, Gerharz CD (2003) Apoptosis induction in renal cell carcinoma by TRAIL and gamma-radiation is impaired by deficient caspase-9 cleavage. Br J Cance r 88:1800-1807
    • (2003) Br J Cance R , vol.88 , pp. 1800-1807
    • Ramp, U.1    Caliskan, E.2    Mahotka, C.3    Krieg, A.4    Heikaus, S.5    Gabbert, H.E.6    Gerharz, C.D.7
  • 153
    • 0030918629 scopus 로고    scopus 로고
    • Acquisition of TGFbeta 1 resistance: An important progression factor in human renal cell carcinoma
    • Ramp U, Jaquet K, Reinecke P, Nitsch T, Gabbert HE, Gerharz CD (1997) Acquisition of TGFbeta 1 resistance: an important progression factor in human renal cell carcinoma. Lab Inves t 76:739-749
    • (1997) Lab Inves T , vol.76 , pp. 739-749
    • Ramp, U.1    Jaquet, K.2    Reinecke, P.3    Nitsch, T.4    Gabbert, H.E.5    Gerharz, C.D.6
  • 154
    • 33645070535 scopus 로고    scopus 로고
    • Renal cyst development in mice with conditional inactivation of the von Hippel-Lindau tumor suppressor
    • Rankin EB, Tomaszewski JE, Haase VH (2006) Renal cyst development in mice with conditional inactivation of the von Hippel-Lindau tumor suppressor. Cancer Res 66:2576-2583
    • (2006) Cancer Res , vol.66 , pp. 2576-2583
    • Rankin, E.B.1    Tomaszewski, J.E.2    Haase, V.H.3
  • 155
    • 0036144387 scopus 로고    scopus 로고
    • Chemopreventive properties of a selective inducible nitric oxide synthase inhibitor in colon carcinogenesis, administered alone or in combination with cel ecoxib, a selective cyclooxygenase-2 inhibitor
    • Rao CV, Indranie C, Simi B, Manning PT, Connor JR, Reddy BS (2002) Chemopreventive properties of a selective inducible nitric oxide synthase inhibitor in colon carcinogenesis, administered alone or in combination with cel ecoxib, a selective cyclooxygenase-2 inhibitor. Cancer Res 62:165-170
    • (2002) Cancer Res , vol.62 , pp. 165-170
    • Rao, C.V.1    Indranie, C.2    Simi, B.3    Manning, P.T.4    Connor, J.R.5    Reddy, B.S.6
  • 157
    • 0033959917 scopus 로고    scopus 로고
    • I dentification and localization of the cytokine SDF1 and its receptor, CXC chemokine receptor 4, to regions of necrosis and angiogenesis in human glioblastoma
    • Rempel SA, Dudas S, Ge S, Gutierrez JA (2000) I dentification and localization of the cytokine SDF1 and its receptor, CXC chemokine receptor 4, to regions of necrosis and angiogenesis in human glioblastoma. Clin Cancer Res 6:102-111
    • (2000) Clin Cancer Res , vol.6 , pp. 102-111
    • Rempel, S.A.1    Dudas, S.2    Ge, S.3    Gutierrez, J.A.4
  • 159
    • 84906899237 scopus 로고    scopus 로고
    • People's Medical Pub. House, McGraw Hill Education, Shelton
    • Rini BI, Campbell SC (2009) Renal cell carcinoma. People's Medical Pub. House, McGraw Hill Education, Shelton
    • (2009) Renal Cell Carcinoma
    • Rini, B.I.1    Campbell, S.C.2
  • 160
    • 12744279328 scopus 로고    scopus 로고
    • A phase i trial of fixed dose rate gemcitabine and capecitabine in metastatic renal cell carcinoma
    • Maidenhead Rini BI, Weinberg V, Small EJ (2005) A phase I trial of fixed dose rate gemcitabine and capecitabine in metastatic renal cell carcinoma. Cancer 103:553-558
    • (2005) Cancer , vol.103 , pp. 553-558
    • Maidenhead Rini, B.I.1    Weinberg, V.2    Small, E.J.3
  • 161
    • 31544455868 scopus 로고    scopus 로고
    • Maximal COX-2 immunostaining and clinical response to celecoxib and interferon alpha therapy in metastatic renal cell carcinoma
    • Rini BI, Weinberg V, Dunlap S, Elchinoff A, Yu N, Bok R, Simko J, Small EJ (2006) Maximal COX-2 immunostaining and clinical response to celecoxib and interferon alpha therapy in metastatic renal cell carcinoma. Cancer 106:566-575
    • (2006) Cancer , vol.106 , pp. 566-575
    • Rini, B.I.1    Weinberg, V.2    Dunlap, S.3    Elchinoff, A.4    Yu, N.5    Bok, R.6    Simko, J.7    Small, E.J.8
  • 162
    • 33845309430 scopus 로고    scopus 로고
    • Activation of the mTOR signaling pathway in renal clear cell carcinoma
    • Robb VA, Karbowniczek M, Klein-Szanto AJ, Henske EP (2007) Activation of the mTOR signaling pathway in renal clear cell carcinoma. J Urol 177:346-352
    • (2007) J Urol , vol.177 , pp. 346-352
    • Robb, V.A.1    Karbowniczek, M.2    Klein-Szanto, A.J.3    Henske, E.P.4
  • 163
    • 60549088732 scopus 로고    scopus 로고
    • Arginase I-producing myeloid-derived suppressor cells in renal cell carcinoma are a subpopulation of activated granulocytes
    • Rodriguez PC, Ernstoff MS, Hernandez C, Atkins M, Zabaleta J, Sierra R, Ochoa AC (2009) Arginase I-producing myeloid-derived suppressor cells in renal cell carcinoma are a subpopulation of activated granulocytes. Cancer Res 69:1553-1560
    • (2009) Cancer Res , vol.69 , pp. 1553-1560
    • Rodriguez, P.C.1    Ernstoff, M.S.2    Hernandez, C.3    Atkins, M.4    Zabaleta, J.5    Sierra, R.6    Ochoa, A.C.7
  • 164
    • 33646140913 scopus 로고    scopus 로고
    • P53 stabilization and transactivation by a von Hippel-Lindau protein
    • Roe JS, Kim H, Lee SM, Kim ST, Cho EJ, Youn HD (2006) p53 stabilization and transactivation by a von Hippel-Lindau protein. Mol Cell 22:395-405
    • (2006) Mol Cell , vol.22 , pp. 395-405
    • Roe, J.S.1    Kim, H.2    Lee, S.M.3    Kim, S.T.4    Cho, E.J.5    Youn, H.D.6
  • 165
    • 33749580272 scopus 로고    scopus 로고
    • Analysis of the expression of HLA class I, proinflammatory cytokines and chemokines in primary t umors from patients with localized and metastatic renal cell carcinoma
    • Romero JM, Aptsiauri N, Vazquez F, Cozar JM, Canton J, Cabrera T, Tallada M, Garrido F, Ruiz-Cabello F (2006) Analysis of the expression of HLA class I, proinflammatory cytokines and chemokines in primary t umors from patients with localized and metastatic renal cell carcinoma. Tissue Antigens 68:303-310
    • (2006) Tissue Antigens , vol.68 , pp. 303-310
    • Romero, J.M.1    Aptsiauri, N.2    Vazquez, F.3    Cozar, J.M.4    Canton, J.5    Cabrera, T.6    Tallada, M.7    Garrido, F.8    Ruiz-Cabello, F.9
  • 166
    • 75149189004 scopus 로고    scopus 로고
    • Role of systemic inflammatory response in predicting survival in patients with primary operable cancer
    • Roxburgh CS, McMillan DC (2010) Role of systemic inflammatory response in predicting survival in patients with primary operable cancer. Future Oncol 6:149-163
    • (2010) Future Oncol , vol.6 , pp. 149-163
    • Roxburgh, C.S.1    McMillan, D.C.2
  • 167
    • 84873258696 scopus 로고    scopus 로고
    • Role of C-reactive protein in urological cancers: A useful biomarker for predicting outcomes
    • Saito K, Kihara K (2013) Role of C-reactive protein in urological cancers: a useful biomarker for predicting outcomes. Int J Urol 20:161-171
    • (2013) Int J Urol , vol.20 , pp. 161-171
    • Saito, K.1    Kihara, K.2
  • 168
    • 62649130234 scopus 로고    scopus 로고
    • Impact of C-reactive protein kinetics on survival of patients with metastatic renal cell carcinoma
    • Saito K, Tatokoro M, Fujii Y, Iimura Y, Koga F, Kawakami S, Kihara K (2009) Impact of C-reactive protein kinetics on survival of patients with metastatic renal cell carcinoma. Eur Urol 55:1145-1153 Sassano A, Platanias LC (2008) Statins in tumor suppression. Cancer Lett 260:11-19
    • (2009) Eur Urol , vol.55 , pp. 1145-1153
    • Saito, K.1    Tatokoro, M.2    Fujii, Y.3    Iimura, Y.4    Koga, F.5    Kawakami, S.6    Kihara, K.7
  • 170
    • 0035874990 scopus 로고    scopus 로고
    • Activated granulocytes and granulocyte-derived hydrogen peroxide are the underlying mechanism of suppression of t-cell function in advanced cancer pa tients
    • Schmielau J, Finn OJ (2001) Activated granulocytes and granulocyte-derived hydrogen peroxide are the underlying mechanism of suppression of t-cell function in advanced cancer pa tients. Cancer Res 61:4756-4760
    • (2001) Cancer Res , vol.61 , pp. 4756-4760
    • Schmielau, J.1    Finn, O.J.2
  • 171
    • 2642536741 scopus 로고    scopus 로고
    • Inflammation, immunity, and HMG-CoA reductase inhibitors: Statins as antiinflammatory agents?
    • Schonbeck U, Libby P (2004) Inflammation, immunity, and HMG-CoA reductase inhibitors: statins as antiinflammatory agents? Circulation 109:II18-II26
    • (2004) Circulation , vol.109
    • Schonbeck, U.1    Libby, P.2
  • 173
  • 174
    • 0031738366 scopus 로고    scopus 로고
    • C XCR-4, a chemokine receptor, is overexpressed in and required for proliferation of glioblastoma tumor cells
    • Sehgal A, Keener C, Boynton AL, Warrick J, Murphy GP (1998) C XCR-4, a chemokine receptor, is overexpressed in and required for proliferation of glioblastoma tumor cells. J Surg Oncol 69:99-104
    • (1998) J Surg Oncol , vol.69 , pp. 99-104
    • Sehgal, A.1    Keener, C.2    Boynton, A.L.3    Warrick, J.4    Murphy, G.P.5
  • 175
    • 0042062324 scopus 로고    scopus 로고
    • Roles of pericellular proteolysis by membrane type-1 matrix metalloproteinase in cancer invasion and angiogenesis
    • Seiki M, Yana I (2003) Roles of pericellular proteolysis by membrane type-1 matrix metalloproteinase in cancer invasion and angiogenesis. Cancer Sci 94:569-574
    • (2003) Cancer Sci , vol.94 , pp. 569-574
    • Seiki, M.1    Yana, I.2
  • 176
    • 0031588388 scopus 로고    scopus 로고
    • Reduced expression of the CXC chemokine hI RH/SDF-1alpha mRNA in hepatoma and digestive tract cancer
    • Shibuta K, Begum NA, Mori M, Shimoda K, Akiyoshi T, Barnard GF (1997) Reduced expression of the CXC chemokine hI RH/SDF-1alpha mRNA in hepatoma and digestive tract cancer. Int J Cancer 73:656-662
    • (1997) Int J Cancer , vol.73 , pp. 656-662
    • Shibuta, K.1    Begum, N.A.2    Mori, M.3    Shimoda, K.4    Akiyoshi, T.5    Barnard, G.F.6
  • 177
    • 84856824651 scopus 로고    scopus 로고
    • Intratumoral injection of CpG oligonucleotides induces the differentiation and reduces the immunosuppressive activity of myeloid-derived suppressor cells
    • Shirota Y, Shirota H, Klinman DM (2012) Intratumoral injection of CpG oligonucleotides induces the differentiation and reduces the immunosuppressive activity of myeloid-derived suppressor cells. J Immunol 188:1592-1599
    • (2012) J Immunol , vol.188 , pp. 1592-1599
    • Shirota, Y.1    Shirota, H.2    Klinman, D.M.3
  • 178
    • 0033213599 scopus 로고    scopus 로고
    • CTLA-4 blockade reverses CD8+ T cell tolerance to tumor by a CD4+ T cell-and IL-2-dependent mechanism
    • Shrikant P, Khoruts A, Mescher MF (1999) CTLA-4 blockade reverses CD8+ T cell tolerance to tumor by a CD4+ T cell-and IL-2-dependent mechanism. Immunity 11:483-493
    • (1999) Immunity , vol.11 , pp. 483-493
    • Shrikant, P.1    Khoruts, A.2    Mescher, M.F.3
  • 179
    • 34248172324 scopus 로고    scopus 로고
    • Altered macrophage differentiation and immune dysfunction in tumor development
    • Sica A Bronte V 2007 Altered macrophage differentiation and immune dysfunction in tumor development J Clin Invest 117: 1155-1166
    • (2007) J Clin Invest , vol.117 , pp. 1155-1166
    • Sica, A.1    Bronte, V.2
  • 180
    • 81255129169 scopus 로고    scopus 로고
    • Neutrophil degranulation and immunosuppression in patients with GBM: Restoration of cellular immune function by targeting ar ginase i
    • Sippel TR, White J, Nag K, Tsvankin V, Klaassen M, Kleinschmidt-Demasters BK, Waziri A (2011) Neutrophil degranulation and immunosuppression in patients with GBM: restoration of cellular immune function by targeting ar ginase I. Clin Cancer Res 17:6992-7002
    • (2011) Clin Cancer Res , vol.17 , pp. 6992-7002
    • Sippel, T.R.1    White, J.2    Nag, K.3    Tsvankin, V.4    Klaassen, M.5    Kleinschmidt- Demasters, B.K.6    Waziri, A.7
  • 183
    • 33749032810 scopus 로고    scopus 로고
    • A phase II s tudy of gemcitabine and capecitabine in metastatic renal cancer: A report of Cancer and Leukemia Group B protocol 90008
    • Stadler WM, Halabi S, Rini B, Ernstoff MS, Davila E, Picus J, Barrier R, Small EJ (2006) A phase II s tudy of gemcitabine and capecitabine in metastatic renal cancer: a report of Cancer and Leukemia Group B protocol 90008. Cancer 107:1273-1279
    • (2006) Cancer , vol.107 , pp. 1273-1279
    • Stadler, W.M.1    Halabi, S.2    Rini, B.3    Ernstoff, M.S.4    Davila, E.5    Picus, J.6    Barrier, R.7    Small, E.J.8
  • 184
    • 0141828145 scopus 로고    scopus 로고
    • Chemokine receptor CXCR4 downregulated by von Hippel-Lindau tumour suppressor pVHL
    • Staller P, Sulitkova J, Lisztwan J, Moch H, Oakeley EJ, Krek W (2003) Chemokine receptor CXCR4 downregulated by von Hippel-Lindau tumour suppressor pVHL. Nature 425:307-311
    • (2003) Nature , vol.425 , pp. 307-311
    • Staller, P.1    Sulitkova, J.2    Lisztwan, J.3    Moch, H.4    Oakeley, E.J.5    Krek, W.6
  • 185
    • 19944430392 scopus 로고    scopus 로고
    • Up-regulation of the interferon gamma (IFN-gamma)-inducible chemokines IFN-inducible T-cell alpha chemoattractant and monokine induced by IFNgamma and of their receptor CXC receptor 3 in human renal cell carcinoma
    • Suyama T, Furuya M, Nishiyama M, Kasuya Y, Kimura S, Ichikawa T, Ueda T, N ikaido T, Ito H, Ishikura H (2005) Up-regulation of the interferon gamma (IFN-gamma)-inducible chemokines IFN-inducible T-cell alpha chemoattractant and monokine induced by IFNgamma and of their receptor CXC receptor 3 in human renal cell carcinoma. Cancer 103:258-267
    • (2005) Cancer , vol.103 , pp. 258-267
    • Suyama, T.1    Furuya, M.2    Nishiyama, M.3    Kasuya, Y.4    Kimura, S.5    Ichikawa, T.6    Ueda, T.7    Ikaido T, N.8    Ito, H.9    Ishikura, H.10
  • 186
    • 0031942989 scopus 로고    scopus 로고
    • Expression of the plasminogen activation system in kidney cancer correlates with its aggressive phenotype
    • Swiercz R, Wolfe JD, Zaher A, Jankun J (1998) Expression of the plasminogen activation system in kidney cancer correlates with its aggressive phenotype. Clin Cancer Re s 4:869-877
    • (1998) Clin Cancer Re S , vol.4 , pp. 869-877
    • Swiercz, R.1    Wolfe, J.D.2    Zaher, A.3    Jankun, J.4
  • 187
    • 84879601217 scopus 로고    scopus 로고
    • Programmed death 1 pathway inhibition in metastatic renal cell cancer and prostate cancer
    • Tang PA, Heng DY (2013) Programmed death 1 pathway inhibition in metastatic renal cell cancer and prostate cancer. Curr Oncol Rep 15:98-104
    • (2013) Curr Oncol Rep , vol.15 , pp. 98-104
    • Tang, P.A.1    Heng, D.Y.2
  • 189
    • 0036595629 scopus 로고    scopus 로고
    • Epith elial-mesenchymal transitions in tumour progression
    • Thiery JP (2002) Epith elial-mesenchymal transitions in tumour progression. Nat Rev Cancer 2:442-454
    • (2002) Nat Rev Cancer , vol.2 , pp. 442-454
    • Thiery, J.P.1
  • 192
    • 34250177269 scopus 로고    scopus 로고
    • PD-1 is expressed by tumor-infiltrating immune cells and is associated with poor outcome for patients with renal cell carcinoma
    • Thompson RH, Dong H, Lohse CM, Leibovich BC, Blute ML, Cheville JC, Kwon ED (2007) PD-1 is expressed by tumor-infiltrating immune cells and is associated with poor outcome for patients with renal cell carcinoma. Clin Cancer Res 13:1757-1761
    • (2007) Clin Cancer Res , vol.13 , pp. 1757-1761
    • Thompson, R.H.1    Dong, H.2    Lohse, C.M.3    Leibovich, B.C.4    Blute, M.L.5    Cheville, J.C.6    Kwon, E.D.7
  • 193
    • 84890787865 scopus 로고    scopus 로고
    • Tissue slice grafts of human renal cell carcinoma: An authentic preclinical model with high engraftment rate and metastatic p otential
    • Thong AE, Zhao H, Ingels A, Valta MP, Nolley R, Santos J, Young SR, Peehl DM (2014) Tissue slice grafts of human renal cell carcinoma: An authentic preclinical model with high engraftment rate and metastatic p otential. Urol Oncol 32:43.e23-43.e30
    • (2014) Urol Oncol , vol.32
    • Thong, A.E.1    Zhao, H.2    Ingels, A.3    Valta, M.P.4    Nolley, R.5    Santos, J.6    Young, S.R.7    Peehl, D.M.8
  • 199
    • 33748450379 scopus 로고    scopus 로고
    • Complex modulation of cell type-specific signaling in response to type i interferons
    • Van Boxel-Dezaire AH, Rani MR, Stark GR (2006) Complex modulation of cell type-specific signaling in response to type I interferons. Immunity 25:361-372
    • (2006) Immunity , vol.25 , pp. 361-372
    • Van Boxel-Dezaire, A.H.1    Rani, M.R.2    Stark, G.R.3
  • 204
    • 0001825042 scopus 로고    scopus 로고
    • Chemokines and their role in tumor growth and metastasis
    • Wang JM, Deng X, Gong W, Su S (1998) Chemokines and their role in tumor growth and metastasis. J Immunol Methods 220:1-17
    • (1998) J Immunol Methods , vol.220 , pp. 1-17
    • Wang, J.M.1    Deng, X.2    Gong, W.3    Su, S.4
  • 205
    • 70449344465 scopus 로고    scopus 로고
    • CXCR4 nuclear l ocalization follows binding of its ligand SDF-1 and occurs in metastatic but not primary renal cell carcinoma
    • Wang L, Wang Z, Yang B, Yang Q, Wang L, Sun Y (2009) CXCR4 nuclear l ocalization follows binding of its ligand SDF-1 and occurs in metastatic but not primary renal cell carcinoma. Oncol Rep 22:1333-1339
    • (2009) Oncol Rep , vol.22 , pp. 1333-1339
    • Wang, L.1    Wang, Z.2    Yang, B.3    Yang, Q.4    Wang, L.5    Sun, Y.6
  • 206
    • 84866980449 scopus 로고    scopus 로고
    • High expression of CXCR4, CXCR7 and SDF-1 predicts poor survival in renal cell carcinoma
    • Wang L, Chen W, Gao L, Yang Q, Liu B, Wu Z, Wang Y, Sun Y (2012a) High expression of CXCR4, CXCR7 and SDF-1 predicts poor survival in renal cell carcinoma. World J Surg Oncol 10:212
    • (2012) World J Surg Oncol , vol.10 , pp. 212
    • Wang, L.1    Chen, W.2    Gao, L.3    Yang, Q.4    Liu, B.5    Wu, Z.6    Wang, Y.7    Sun, Y.8
  • 207
    • 84868095010 scopus 로고    scopus 로고
    • Silencing of CXCR4 by RNA interference inhibits cell growth and metastasis in human renal cancer cells
    • Wang L, Huang T, Chen W, Gao X, Zhou T, Wu Z, Sun Y (2012b) Silencing of CXCR4 by RNA interference inhibits cell growth and metastasis in human renal cancer cells. Oncol Rep 28:2043-2048
    • (2012) Oncol Rep , vol.28 , pp. 2043-2048
    • Wang, L.1    Huang, T.2    Chen, W.3    Gao, X.4    Zhou, T.5    Wu, Z.6    Sun, Y.7
  • 208
    • 84873973938 scopus 로고    scopus 로고
    • Chemoprevention of cancers in gastrointestinal tract with cyclooxygenase 2 inhibitors
    • Wang R, Guo L, Wang P, Yang W, Lu Y, Huang Z, Tang C (2013) Chemoprevention of cancers in gastrointestinal tract with cyclooxygenase 2 inhibitors. Curr Pharm Des 19:115-125
    • (2013) Curr Pharm des , vol.19 , pp. 115-125
    • Wang, R.1    Guo, L.2    Wang, P.3    Yang, W.4    Lu, Y.5    Huang, Z.6    Tang, C.7
  • 210
    • 0030067276 scopus 로고    scopus 로고
    • Administration of interleukin 12 with pulse interleukin 2 and the rapid and complete eradication of murine renal carcinoma
    • Wigginton JM, Komschlies KL, Ba ck TC, Franco JL, Brunda MJ, Wiltrout RH (1996) Administration of interleukin 12 with pulse interleukin 2 and the rapid and complete eradication of murine renal carcinoma. J Natl Cancer Inst 88:38-43
    • (1996) J Natl Cancer Inst , vol.88 , pp. 38-43
    • Wigginton, J.M.1    Komschlies, K.L.2    Ba Ck, T.C.3    Franco, J.L.4    Brunda, M.J.5    Wiltrout, R.H.6
  • 211
    • 0028928749 scopus 로고
    • Chemotherapy for advanced renal-cell carcinoma: 1983-1993
    • Ya goda A, Abi-Rached B, Petrylak D (1995) Chemotherapy for advanced renal-cell carcinoma: 1983-1993. Semin Oncol 22:42-60
    • (1995) Semin Oncol , vol.22 , pp. 42-60
    • Ya Goda, A.1    Abi-Rached, B.2    Petrylak, D.3
  • 215
    • 0037903231 scopus 로고    scopus 로고
    • Roles of matrix metalloproteinases in tumor metastasis and angiogenesis
    • Yoon SO, Park SJ, Yun CH, Chung AS (2003) Roles of matrix metalloproteinases in tumor metastasis and angiogenesis. J Biochem Mol Biol 36:128-137
    • (2003) J Biochem Mol Biol , vol.36 , pp. 128-137
    • Yoon, S.O.1    Park, S.J.2    Yun, C.H.3    Chung, A.S.4
  • 217
    • 84855301911 scopus 로고    scopus 로고
    • Characterization of the nature of granulocytic myeloid-derived suppressor cells in tumor-bearing mice
    • Youn JI, Collazo M, Shalova IN, Biswas SK, Gabrilovich DI (2012 ) Characterization of the nature of granulocytic myeloid-derived suppressor cells in tumor-bearing mice. J Leukoc Biol 91:167-181
    • (2012) J Leukoc Biol , vol.91 , pp. 167-181
    • Youn, J.I.1    Collazo, M.2    Shalova, I.N.3    Biswas, S.K.4    Gabrilovich, D.I.5
  • 218
    • 0034979275 scopus 로고    scopus 로고
    • Signaling mechanisms mediating vascular protective actions of vascular endothelial growth factor
    • Zachary I (2001) Signaling mechanisms mediating vascular protective actions of vascular endothelial growth factor. Am J Physiol Cell Physiol 280:C1375-C1386
    • (2001) Am J Physiol Cell Physiol , vol.280
    • Zachary, I.1
  • 219
    • 0036645091 scopus 로고    scopus 로고
    • Identification of cyclin D1 and other novel targets for the von Hippel-Lindau tumor suppressor gene by expression array analysis and investigation of cyclin D1 genotype as a modifier in von Hippel-Lindau disease
    • Zatyka M, da Silva NF, Clifford SC, Morris MR, Wiesener MS, Eckardt KU, Houlston RS, Richards FM, Latif F, Ma her ER (2002) Identification of cyclin D1 and other novel targets for the von Hippel-Lindau tumor suppressor gene by expression array analysis and investigation of cyclin D1 genotype as a modifier in von Hippel-Lindau disease. Cancer Res 62:3803-3811
    • (2002) Cancer Res , vol.62 , pp. 3803-3811
    • Zatyka, M.1    Da Silva, N.F.2    Clifford, S.C.3    Morris, M.R.4    Wiesener, M.S.5    Eckardt, K.U.6    Houlston, R.S.7    Richards, F.M.8    Latif, F.9    Ma Her, E.R.10
  • 221
    • 0027979731 scopus 로고
    • Human monocytes are stimulated for nitric oxide release in vitro by some tumor cells but not by cytokines and lipopolysaccharide
    • Zembala M, Siedlar M, Marcinkiewicz J, Pryjma J (1994) Human monocytes are stimulated for nitric oxide release in vitro by some tumor cells but not by cytokines and lipopolysaccharide. Eur J Immunol 24:435-439
    • (1994) Eur J Immunol , vol.24 , pp. 435-439
    • Zembala, M.1    Siedlar, M.2    Marcinkiewicz, J.3    Pryjma, J.4
  • 222
    • 0033617193 scopus 로고    scopus 로고
    • CC chemokine receptor-3 undergoes prolonged ligand-induced internalization
    • Zimmermann N, Conkright JJ, Rothenberg ME (1999) CC chemokine receptor-3 undergoes prolonged ligand-induced internalization. J Biol Chem 274:12611-12618
    • (1999) J Biol Chem , vol.274 , pp. 12611-12618
    • Zimmermann, N.1    Conkright, J.J.2    Rothenberg, M.E.3
  • 223


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.