Nox4 mediates renal cell carcinoma cell invasion through hypoxia-induced interleukin 6- and 8- production

PLoS ONE

Volumn 7, Issue 1, 2012, Pages

  Fitzgerald, John P ^b   Nayak, Bijaya ^b   Shanmugasundaram, Karthigayan ^b   Friedrichs, William ^b   Sudarshan, Sunil ^b   Eid, Assaad A ^b   DeNapoli, Thomas ^b   Parekh, Dipen J ^b   Gorin, Yves ^b   Block, Karen ^a,b  

^a UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^b Mays Cancer Center at UT Health San Antonio   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

5 AMINO 4 IMIDAZOLECARBOXAMIDE RIBOSIDE; ACETYLCYSTEINE; DIPHENYLIODONIUM SALT; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; INTERLEUKIN 6; INTERLEUKIN 8; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 4; SMALL INTERFERING RNA; 5 AMINO 4 IMIDAZOLECARBOXAMIDE; AICA RIBONUCLEOTIDE; ANTIOXIDANT; DRUG DERIVATIVE; NOX4 PROTEIN, HUMAN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; RIBONUCLEOTIDE;

ARTICLE; CANCER INVASION; CELL HYPOXIA; CELL MIGRATION; CELL PH; CELL VIABILITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME ACTIVATION; ENZYME ACTIVITY; EX VIVO STUDY; HUMAN; HUMAN CELL; HUMAN TISSUE; KIDNEY CARCINOMA; METASTASIS; MOLECULAR DYNAMICS; PROTEIN EXPRESSION; PROTEIN FUNCTION; TUMOR MICROENVIRONMENT; BIOSYNTHESIS; DRUG EFFECT; ENZYMOLOGY; KIDNEY TUMOR; METABOLISM; PATHOLOGY; TUMOR CELL LINE;

AMINOIMIDAZOLE CARBOXAMIDE; AMP-ACTIVATED PROTEIN KINASES; ANTIOXIDANTS; CARCINOMA, RENAL CELL; CELL HYPOXIA; CELL LINE, TUMOR; ENZYME ACTIVATION; HUMANS; INTERLEUKIN-6; INTERLEUKIN-8; KIDNEY NEOPLASMS; NADPH OXIDASE; NEOPLASM INVASIVENESS; RIBONUCLEOTIDES;

EID: 84856404470     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0030712     Document Type: Article

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