HIF1α delays premature senescence through the activation of MIF

Genes and Development

Volumn 20, Issue 24, 2006, Pages 3366-3371

  Welford, Scott M ^a   Bedogni, Barbara ^a   Gradin, Katarina ^b   Poellinger, Lorenz ^b   Powell, Marianne Broome ^a   Giaccia, Amato J ^a  

^a STANFORD UNIVERSITY   (United States)

^b KAROLINSKA INSTITUTE   (Sweden)

Author keywords

HIF1 ; Hypoxia; MIF; Oxidative stress; Senescence

Indexed keywords

HYPOXIA INDUCIBLE FACTOR 1ALPHA; MACROPHAGE MIGRATION INHIBITION FACTOR; HIF1A PROTEIN, MOUSE; ISOMERASE; MIF PROTEIN, MOUSE;

ANIMAL CELL; ARTICLE; CELL AGING; CELL PROLIFERATION; CONTROLLED STUDY; EMBRYO CELL; FIBROBLAST; GAMMA IRRADIATION; HYPOXIA; KNOCKOUT MOUSE; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN FUNCTION; SENESCENCE; AEROBIC METABOLISM; ANIMAL; CELL HYPOXIA; GAMMA RADIATION; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; MOUSE MUTANT; PHYSIOLOGY; RADIATION EXPOSURE;

AEROBIOSIS; ANIMALS; CELL AGING; CELL HYPOXIA; FIBROBLASTS; GAMMA RAYS; GENE EXPRESSION REGULATION; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; INTRAMOLECULAR OXIDOREDUCTASES; MACROPHAGE MIGRATION-INHIBITORY FACTORS; MICE; MICE, KNOCKOUT; TRANSCRIPTION, GENETIC;

EID: 33845710642     PISSN: 08909369     EISSN: 15495477     Source Type: Journal    
DOI: 10.1101/gad.1471106     Document Type: Article

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