-
1
-
-
33646804507
-
Mechanisms of immune evasion by tumors
-
10.1016/S0065-2776(06)90002-9 16730261 10.1016/S0065-2776(06)90002-9 1:CAS:528:DC%2BD1cXhsVCjur4%3D
-
Drake CG, Jaffee E, Pardoll DM. Mechanisms of immune evasion by tumors. Adv Immunol. 2006;90:51-81. doi: 10.1016/S0065-2776(06)90002-9.
-
(2006)
Adv Immunol
, vol.90
, pp. 51-81
-
-
Drake, C.G.1
Jaffee, E.2
Pardoll, D.M.3
-
2
-
-
84255197842
-
Cancer immunotherapy comes of age
-
10.1038/nature10673 22193102 10.1038/nature10673 1:CAS:528: DC%2BC3MXhs1GksLjO
-
Mellman I, Coukos G, Dranoff G. Cancer immunotherapy comes of age. Nature. 2011;480(7378):480-9. doi: 10.1038/nature10673.
-
(2011)
Nature
, vol.480
, Issue.7378
, pp. 480-489
-
-
Mellman, I.1
Coukos, G.2
Dranoff, G.3
-
3
-
-
0027056895
-
Alterations in signal transduction molecules in T lymphocytes from tumor-bearing mice
-
1465616 10.1126/science.1465616 1:CAS:528:DyaK3sXlslOjsg%3D%3D
-
Mizoguchi H, O'Shea JJ, Longo DL, Loeffler CM, McVicar DW, Ochoa AC. Alterations in signal transduction molecules in T lymphocytes from tumor-bearing mice. Science. 1992;258(5089):1795-8.
-
(1992)
Science
, vol.258
, Issue.5089
, pp. 1795-1798
-
-
Mizoguchi, H.1
O'Shea, J.J.2
Longo, D.L.3
Loeffler, C.M.4
McVicar, D.W.5
Ochoa, A.C.6
-
4
-
-
84555218419
-
Cancer immunotherapy comes of age
-
10.1200/JCO.2011.38.0899 22042955 10.1200/JCO.2011.38.0899 1:CAS:528:DC%2BC38Xhslygs7k%3D
-
Topalian SL, Weiner GJ, Pardoll DM. Cancer immunotherapy comes of age. J Clin Oncol. 2011;29(36):4828-36. doi: 10.1200/JCO.2011.38.0899.
-
(2011)
J Clin Oncol
, vol.29
, Issue.36
, pp. 4828-4836
-
-
Topalian, S.L.1
Weiner, G.J.2
Pardoll, D.M.3
-
5
-
-
84858766182
-
The blockade of immune checkpoints in cancer immunotherapy
-
10.1038/nrc3239 22437870 10.1038/nrc3239 1:CAS:528:DC%2BC38XksVegtrw%3D This is an excellent review explaining the basic science of immune checkpoints and the implications for cancer immunotherapy
-
• Pardoll DM. The blockade of immune checkpoints in cancer immunotherapy. Nat Rev Cancer. 2012;12(4):252-64. doi: 10.1038/nrc3239. This is an excellent review explaining the basic science of immune checkpoints and the implications for cancer immunotherapy.
-
(2012)
Nat Rev Cancer
, vol.12
, Issue.4
, pp. 252-264
-
-
Pardoll, D.M.1
-
6
-
-
77954801079
-
Improved survival with ipilimumab in patients with metastatic melanoma
-
10.1056/NEJMoa1003466 20525992 10.1056/NEJMoa1003466 1:CAS:528: DC%2BC3cXhtVCrtrbN
-
Hodi FS, O'Day SJ, McDermott DF, Weber RW, Sosman JA, Haanen JB, et al. Improved survival with ipilimumab in patients with metastatic melanoma. N Engl J Med. 2010;363(8):711-23. doi: 10.1056/NEJMoa1003466.
-
(2010)
N Engl J Med
, vol.363
, Issue.8
, pp. 711-723
-
-
Hodi, F.S.1
O'Day, S.J.2
McDermott, D.F.3
Weber, R.W.4
Sosman, J.A.5
Haanen, J.B.6
-
7
-
-
79959772576
-
Ipilimumab plus dacarbazine for previously untreated metastatic melanoma
-
10.1056/NEJMoa1104621 21639810 10.1056/NEJMoa1104621 1:CAS:528: DC%2BC3MXosVegtro%3D
-
Robert C, Thomas L, Bondarenko I, O'Day S, Weber J, Garbe C, et al. Ipilimumab plus dacarbazine for previously untreated metastatic melanoma. N Engl J Med. 2011;364(26):2517-26. doi: 10.1056/NEJMoa1104621.
-
(2011)
N Engl J Med
, vol.364
, Issue.26
, pp. 2517-2526
-
-
Robert, C.1
Thomas, L.2
Bondarenko, I.3
O'Day, S.4
Weber, J.5
Garbe, C.6
-
8
-
-
0033180181
-
Development of lupus-like autoimmune diseases by disruption of the PD-1 gene encoding an ITIM motif-carrying immunoreceptor
-
10485649 10.1016/S1074-7613(00)80089-8 1:CAS:528:DyaK1MXlvVShsb8%3D
-
Nishimura H, Nose M, Hiai H, Minato N, Honjo T. Development of lupus-like autoimmune diseases by disruption of the PD-1 gene encoding an ITIM motif-carrying immunoreceptor. Immunity. 1999;11(2):141-51.
-
(1999)
Immunity
, vol.11
, Issue.2
, pp. 141-151
-
-
Nishimura, H.1
Nose, M.2
Hiai, H.3
Minato, N.4
Honjo, T.5
-
9
-
-
34547794178
-
PD-1 and PD-1 ligands: From discovery to clinical application
-
10.1093/intimm/dxm057 17606980 10.1093/intimm/dxm057 1:CAS:528: DC%2BD2sXhtValtbbO
-
Okazaki T, Honjo T. PD-1 and PD-1 ligands: from discovery to clinical application. Int Immunol. 2007;19(7):813-24. doi: 10.1093/intimm/dxm057.
-
(2007)
Int Immunol
, vol.19
, Issue.7
, pp. 813-824
-
-
Okazaki, T.1
Honjo, T.2
-
10
-
-
0032736029
-
B7-H1, a third member of the B7 family, co-stimulates T-cell proliferation and interleukin-10 secretion
-
10.1038/70932 10581077 10.1038/70932 1:CAS:528:DyaK1MXnvFCqt74%3D
-
Dong H, Zhu G, Tamada K, Chen L. B7-H1, a third member of the B7 family, co-stimulates T-cell proliferation and interleukin-10 secretion. Nat Med. 1999;5(12):1365-9. doi: 10.1038/70932.
-
(1999)
Nat Med
, vol.5
, Issue.12
, pp. 1365-1369
-
-
Dong, H.1
Zhu, G.2
Tamada, K.3
Chen, L.4
-
11
-
-
0034596948
-
Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation
-
11015443 10.1084/jem.192.7.1027 1:CAS:528:DC%2BD3cXntFSlt7o%3D
-
Freeman GJ, Long AJ, Iwai Y, Bourque K, Chernova T, Nishimura H, et al. Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation. J Exp Med. 2000;192(7):1027-34.
-
(2000)
J Exp Med
, vol.192
, Issue.7
, pp. 1027-1034
-
-
Freeman, G.J.1
Long, A.J.2
Iwai, Y.3
Bourque, K.4
Chernova, T.5
Nishimura, H.6
-
12
-
-
5844264920
-
PD-L2 is a second ligand for PD-1 and inhibits T cell activation
-
10.1038/85330 11224527 10.1038/85330 1:CAS:528:DC%2BD3MXhvVaksrc%3D
-
Latchman Y, Wood CR, Chernova T, Chaudhary D, Borde M, Chernova I, et al. PD-L2 is a second ligand for PD-1 and inhibits T cell activation. Nat Immunol. 2001;2(3):261-8. doi: 10.1038/85330.
-
(2001)
Nat Immunol
, vol.2
, Issue.3
, pp. 261-268
-
-
Latchman, Y.1
Wood, C.R.2
Chernova, T.3
Chaudhary, D.4
Borde, M.5
Chernova, I.6
-
13
-
-
0035794314
-
B7-DC, a new dendritic cell molecule with potent costimulatory properties for T cells
-
11283156 10.1084/jem.193.7.839 1:CAS:528:DC%2BD3MXisVyhurg%3D
-
Tseng SY, Otsuji M, Gorski K, Huang X, Slansky JE, Pai SI, et al. B7-DC, a new dendritic cell molecule with potent costimulatory properties for T cells. J Exp Med. 2001;193(7):839-46.
-
(2001)
J Exp Med
, vol.193
, Issue.7
, pp. 839-846
-
-
Tseng, S.Y.1
Otsuji, M.2
Gorski, K.3
Huang, X.4
Slansky, J.E.5
Pai, S.I.6
-
14
-
-
0038273853
-
Blockade of B7-H1 improves myeloid dendritic cell-mediated antitumor immunity
-
10.1038/nm863 12704383 10.1038/nm863 1:CAS:528:DC%2BD3sXjtlamtLc%3D
-
Curiel TJ, Wei S, Dong H, Alvarez X, Cheng P, Mottram P, et al. Blockade of B7-H1 improves myeloid dendritic cell-mediated antitumor immunity. Nat Med. 2003;9(5):562-7. doi: 10.1038/nm863.
-
(2003)
Nat Med
, vol.9
, Issue.5
, pp. 562-567
-
-
Curiel, T.J.1
Wei, S.2
Dong, H.3
Alvarez, X.4
Cheng, P.5
Mottram, P.6
-
15
-
-
0037126021
-
Involvement of PD-L1 on tumor cells in the escape from host immune system and tumor immunotherapy by PD-L1 blockade
-
10.1073/pnas.192461099 12218188 10.1073/pnas.192461099 1:CAS:528:DC%2BD38XntlCksL8%3D
-
Iwai Y, Ishida M, Tanaka Y, Okazaki T, Honjo T, Minato N. Involvement of PD-L1 on tumor cells in the escape from host immune system and tumor immunotherapy by PD-L1 blockade. Proc Natl Acad Sci U S A. 2002;99(19):12293-7. doi: 10.1073/pnas.192461099.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, Issue.19
, pp. 12293-12297
-
-
Iwai, Y.1
Ishida, M.2
Tanaka, Y.3
Okazaki, T.4
Honjo, T.5
Minato, N.6
-
16
-
-
44349150012
-
Inhibitory B7-family molecules in the tumour microenvironment
-
10.1038/nri2326 18500231 10.1038/nri2326 1:CAS:528:DC%2BD1cXmt1Ojt74%3D
-
Zou W, Chen L. Inhibitory B7-family molecules in the tumour microenvironment. Nat Rev Immunol. 2008;8(6):467-77. doi: 10.1038/nri2326.
-
(2008)
Nat Rev Immunol
, vol.8
, Issue.6
, pp. 467-477
-
-
Zou, W.1
Chen, L.2
-
17
-
-
84862903106
-
Safety and activity of Anti-PD-L1 antibody in patients with advanced cancer
-
10.1056/NEJMoa1200694 22658128 10.1056/NEJMoa1200694 1:CAS:528: DC%2BC38XhtV2rsbnJ This article reviews the clinical activity and toxicity of anti-PD-L1 antibody BMS-936559 in patients with advanced solid tumors
-
• Brahmer JR, Tykodi SS, Chow LQM, Hwu W-J, Topalian SL, Hwu P, et al. Safety and activity of Anti-PD-L1 antibody in patients with advanced cancer. N Engl J Med. 2012;366(26):2455-65. doi: 10.1056/NEJMoa1200694. This article reviews the clinical activity and toxicity of anti-PD-L1 antibody BMS-936559 in patients with advanced solid tumors.
-
(2012)
N Engl J Med
, vol.366
, Issue.26
, pp. 2455-2465
-
-
Brahmer, J.R.1
Tykodi, S.S.2
Chow, L.Q.M.3
Hwu, W.-J.4
Topalian, S.L.5
Hwu, P.6
-
18
-
-
84862859820
-
Safety, activity, and immune correlates of anti-PD-1 antibody in cancer
-
10.1056/NEJMoa1200690 22658127 10.1056/NEJMoa1200690 1:CAS:528: DC%2BC38XhtV2rs7fN This article reviews the clinical activity and toxicity of anti-PD1 antibody BMS-936558 in patients with advanced solid tumors
-
• Topalian SL, Hodi FS, Brahmer JR, Gettinger SN, Smith DC, McDermott DF, et al. Safety, activity, and immune correlates of anti-PD-1 antibody in cancer. N Engl J Med. 2012;366(26):2443-54. doi: 10.1056/NEJMoa1200690. This article reviews the clinical activity and toxicity of anti-PD1 antibody BMS-936558 in patients with advanced solid tumors.
-
(2012)
N Engl J Med
, vol.366
, Issue.26
, pp. 2443-2454
-
-
Topalian, S.L.1
Hodi, F.S.2
Brahmer, J.R.3
Gettinger, S.N.4
Smith, D.C.5
McDermott, D.F.6
-
19
-
-
80051698136
-
IL-18 induces PD-1-dependent immunosuppression in cancer
-
10.1158/0008-5472.CAN-11-0993 21724589 10.1158/0008-5472.CAN-11-0993 1:CAS:528:DC%2BC3MXhtVSrtbzE
-
Terme M, Ullrich E, Aymeric L, Meinhardt K, Desbois M, Delahaye N, et al. IL-18 induces PD-1-dependent immunosuppression in cancer. Cancer Res. 2011;71(16):5393-9. doi: 10.1158/0008-5472.CAN-11-0993.
-
(2011)
Cancer Res
, vol.71
, Issue.16
, pp. 5393-5399
-
-
Terme, M.1
Ullrich, E.2
Aymeric, L.3
Meinhardt, K.4
Desbois, M.5
Delahaye, N.6
-
20
-
-
0026700235
-
Induced expression of PD-1, a novel member of the immunoglobulin gene superfamily, upon programmed cell death
-
1396582 1:CAS:528:DyaK3sXkslShtbs%3D
-
Ishida Y, Agata Y, Shibahara K, Honjo T. Induced expression of PD-1, a novel member of the immunoglobulin gene superfamily, upon programmed cell death. EMBO J. 1992;11(11):3887-95.
-
(1992)
EMBO J
, vol.11
, Issue.11
, pp. 3887-3895
-
-
Ishida, Y.1
Agata, Y.2
Shibahara, K.3
Honjo, T.4
-
21
-
-
0842325739
-
PD-L1/B7H-1 inhibits the effector phase of tumor rejection by T cell receptor (TCR) transgenic CD8+ T cells
-
14871849 10.1158/0008-5472.CAN-03-3259 1:CAS:528:DC%2BD2cXhtFCgtrs%3D
-
Blank C, Brown I, Peterson AC, Spiotto M, Iwai Y, Honjo T, et al. PD-L1/B7H-1 inhibits the effector phase of tumor rejection by T cell receptor (TCR) transgenic CD8+ T cells. Cancer Res. 2004;64(3):1140-5.
-
(2004)
Cancer Res
, vol.64
, Issue.3
, pp. 1140-1145
-
-
Blank, C.1
Brown, I.2
Peterson, A.C.3
Spiotto, M.4
Iwai, Y.5
Honjo, T.6
-
22
-
-
18544380239
-
Tumor-associated B7-H1 promotes T-cell apoptosis: A potential mechanism of immune evasion
-
10.1038/nm730 12091876 1:CAS:528:DC%2BD38Xls12msLo%3D Erratum, Nat Med 2002;8:1039
-
Dong H, Strome SE, Salomao DR, Tamura H, Hirano F, Flies DB, et al. Tumor-associated B7-H1 promotes T-cell apoptosis: a potential mechanism of immune evasion. Nat Med. 2002;8(8):793-800. doi: 10.1038/nm730. Erratum, Nat Med 2002;8:1039.
-
(2002)
Nat Med
, vol.8
, Issue.8
, pp. 793-800
-
-
Dong, H.1
Strome, S.E.2
Salomao, D.R.3
Tamura, H.4
Hirano, F.5
Flies, D.B.6
-
23
-
-
77956496386
-
B7-H1/CD80 interaction is required for the induction and maintenance of peripheral T-cell tolerance
-
10.1182/blood-2010-01-265975 20472828 10.1182/blood-2010-01-265975 1:CAS:528:DC%2BC3cXhtFersbbP
-
Park JJ, Omiya R, Matsumura Y, Sakoda Y, Kuramasu A, Augustine MM, et al. B7-H1/CD80 interaction is required for the induction and maintenance of peripheral T-cell tolerance. Blood. 2010;116(8):1291-8. doi: 10.1182/blood-2010-01-265975.
-
(2010)
Blood
, vol.116
, Issue.8
, pp. 1291-1298
-
-
Park, J.J.1
Omiya, R.2
Matsumura, Y.3
Sakoda, Y.4
Kuramasu, A.5
Augustine, M.M.6
-
24
-
-
80051619906
-
The programmed death-1 ligand 1:B7-1 pathway restrains diabetogenic effector T cells in vivo
-
10.4049/jimmunol.1003496 21697456 10.4049/jimmunol.1003496 1:CAS:528:DC%2BC3MXptVamsLg%3D
-
Paterson AM, Brown KE, Keir ME, Vanguri VK, Riella LV, Chandraker A, et al. The programmed death-1 ligand 1:B7-1 pathway restrains diabetogenic effector T cells in vivo. J Immunol. 2011;187(3):1097-105. doi: 10.4049/jimmunol. 1003496.
-
(2011)
J Immunol
, vol.187
, Issue.3
, pp. 1097-1105
-
-
Paterson, A.M.1
Brown, K.E.2
Keir, M.E.3
Vanguri, V.K.4
Riella, L.V.5
Chandraker, A.6
-
25
-
-
62249172189
-
Enhancing SIV-specific immunity in vivo by PD-1 blockade
-
10.1038/nature07662 19078956 10.1038/nature07662 1:CAS:528: DC%2BD1MXht1ehu74%3D
-
Velu V, Titanji K, Zhu B, Husain S, Pladevega A, Lai L, et al. Enhancing SIV-specific immunity in vivo by PD-1 blockade. Nature. 2009;458(7235):206-10. doi: 10.1038/nature07662.
-
(2009)
Nature
, vol.458
, Issue.7235
, pp. 206-210
-
-
Velu, V.1
Titanji, K.2
Zhu, B.3
Husain, S.4
Pladevega, A.5
Lai, L.6
-
26
-
-
37249067503
-
CD8+ Foxp3+ regulatory T cells mediate immunosuppression in prostate cancer
-
10.1158/1078-0432.CCR-07-0842 18056169 10.1158/1078-0432.CCR-07-0842 1:CAS:528:DC%2BD2sXhtlyit7fF
-
Kiniwa Y, Miyahara Y, Wang HY, Peng W, Peng G, Wheeler TM, et al. CD8+ Foxp3+ regulatory T cells mediate immunosuppression in prostate cancer. Clin Cancer Res. 2007;13(23):6947-58. doi: 10.1158/1078-0432.CCR-07-0842.
-
(2007)
Clin Cancer Res
, vol.13
, Issue.23
, pp. 6947-6958
-
-
Kiniwa, Y.1
Miyahara, Y.2
Wang, H.Y.3
Peng, W.4
Peng, G.5
Wheeler, T.M.6
-
27
-
-
33750807427
-
CD4+CD25high T cells are enriched in the tumor and peripheral blood of prostate cancer patients
-
17082659 1:CAS:528:DC%2BD28XhtFGrtrfM
-
Miller AM, Lundberg K, Ozenci V, Banham AH, Hellstrom M, Egevad L, et al. CD4+CD25high T cells are enriched in the tumor and peripheral blood of prostate cancer patients. J Immunol. 2006;177(10):7398-405.
-
(2006)
J Immunol
, vol.177
, Issue.10
, pp. 7398-7405
-
-
Miller, A.M.1
Lundberg, K.2
Ozenci, V.3
Banham, A.H.4
Hellstrom, M.5
Egevad, L.6
-
28
-
-
48849103649
-
Phenotypic analysis of prostate-infiltrating lymphocytes reveals TH17 and Treg skewing
-
10.1158/1078-0432.CCR-07-5164 18519750 10.1158/1078-0432.CCR-07-5164 1:CAS:528:DC%2BD1cXmslygs70%3D
-
Sfanos KS, Bruno TC, Maris CH, Xu L, Thoburn CJ, DeMarzo AM, et al. Phenotypic analysis of prostate-infiltrating lymphocytes reveals TH17 and Treg skewing. Clin Cancer Res. 2008;14(11):3254-61. doi: 10.1158/1078-0432.CCR-07- 5164.
-
(2008)
Clin Cancer Res
, vol.14
, Issue.11
, pp. 3254-3261
-
-
Sfanos, K.S.1
Bruno, T.C.2
Maris, C.H.3
Xu, L.4
Thoburn, C.J.5
Demarzo, A.M.6
-
29
-
-
77955066199
-
Sipuleucel-T immunotherapy for castration-resistant prostate cancer
-
10.1056/NEJMoa1001294 20818862 10.1056/NEJMoa1001294 1:CAS:528: DC%2BC3cXhtVGlurrN
-
Kantoff PW, Higano CS, Shore ND, Berger ER, Small EJ, Penson DF, et al. Sipuleucel-T immunotherapy for castration-resistant prostate cancer. N Engl J Med. 2010;363(5):411-22. doi: 10.1056/NEJMoa1001294.
-
(2010)
N Engl J Med
, vol.363
, Issue.5
, pp. 411-422
-
-
Kantoff, P.W.1
Higano, C.S.2
Shore, N.D.3
Berger, E.R.4
Small, E.J.5
Penson, D.F.6
-
30
-
-
65849449107
-
Prostate cancer lesions are surrounded by FOXP3+, PD-1+ and B7-H1+ lymphocyte clusters
-
10.1016/j.ejca.2009.02.015 19318244 10.1016/j.ejca.2009.02.015 1:CAS:528:DC%2BD1MXms1WmtLk%3D
-
Ebelt K, Babaryka G, Frankenberger B, Stief CG, Eisenmenger W, Kirchner T, et al. Prostate cancer lesions are surrounded by FOXP3+, PD-1+ and B7-H1+ lymphocyte clusters. Eur J Cancer. 2009;45(9):1664-72. doi: 10.1016/j.ejca.2009. 02.015.
-
(2009)
Eur J Cancer
, vol.45
, Issue.9
, pp. 1664-1672
-
-
Ebelt, K.1
Babaryka, G.2
Frankenberger, B.3
Stief, C.G.4
Eisenmenger, W.5
Kirchner, T.6
-
31
-
-
34250177269
-
PD-1 is expressed by tumor-infiltrating immune cells and is associated with poor outcome for patients with renal cell carcinoma
-
10.1158/1078-0432.CCR-06-2599 17363529 10.1158/1078-0432.CCR-06-2599 1:CAS:528:DC%2BD2sXivV2gt7k%3D
-
Thompson RH, Dong H, Lohse CM, Leibovich BC, Blute ML, Cheville JC, et al. PD-1 is expressed by tumor-infiltrating immune cells and is associated with poor outcome for patients with renal cell carcinoma. Clin Cancer Res. 2007;13(6):1757-61. doi: 10.1158/1078-0432.CCR-06-2599.
-
(2007)
Clin Cancer Res
, vol.13
, Issue.6
, pp. 1757-1761
-
-
Thompson, R.H.1
Dong, H.2
Lohse, C.M.3
Leibovich, B.C.4
Blute, M.L.5
Cheville, J.C.6
-
32
-
-
33645736792
-
Tumor B7-H1 is associated with poor prognosis in renal cell carcinoma patients with long-term follow-up
-
10.1158/0008-5472.CAN-05-4303 16585157 10.1158/0008-5472.CAN-05-4303 1:CAS:528:DC%2BD28XjtVOkt7w%3D
-
Thompson RH, Kuntz SM, Leibovich BC, Dong H, Lohse CM, Webster WS, et al. Tumor B7-H1 is associated with poor prognosis in renal cell carcinoma patients with long-term follow-up. Cancer Res. 2006;66(7):3381-5. doi: 10.1158/0008-5472.CAN-05-4303.
-
(2006)
Cancer Res
, vol.66
, Issue.7
, pp. 3381-3385
-
-
Thompson, R.H.1
Kuntz, S.M.2
Leibovich, B.C.3
Dong, H.4
Lohse, C.M.5
Webster, W.S.6
-
33
-
-
79953306651
-
Identification of a soluble form of B7-H1 that retains immunosuppressive activity and is associated with aggressive renal cell carcinoma
-
10.1158/1078-0432.CCR-10-0250 21355078 10.1158/1078-0432.CCR-10-0250 1:CAS:528:DC%2BC3MXktVOisLY%3D
-
Frigola X, Inman BA, Lohse CM, Krco CJ, Cheville JC, Thompson RH, et al. Identification of a soluble form of B7-H1 that retains immunosuppressive activity and is associated with aggressive renal cell carcinoma. Clin Cancer Res. 2011;17(7):1915-23. doi: 10.1158/1078-0432.CCR-10-0250.
-
(2011)
Clin Cancer Res
, vol.17
, Issue.7
, pp. 1915-1923
-
-
Frigola, X.1
Inman, B.A.2
Lohse, C.M.3
Krco, C.J.4
Cheville, J.C.5
Thompson, R.H.6
-
34
-
-
73149092567
-
Guidelines for the evaluation of immune therapy activity in solid tumors: Immune-related response criteria
-
10.1158/1078-0432.CCR-09-1624 19934295 10.1158/1078-0432.CCR-09-1624 1:CAS:528:DC%2BD1MXhsFSnu7vN
-
Wolchok JD, Hoos A, O'Day S, Weber JS, Hamid O, Lebbe C, et al. Guidelines for the evaluation of immune therapy activity in solid tumors: immune-related response criteria. Clin Cancer Res. 2009;15(23):7412-20. doi: 10.1158/1078-0432.CCR-09-1624.
-
(2009)
Clin Cancer Res
, vol.15
, Issue.23
, pp. 7412-7420
-
-
Wolchok, J.D.1
Hoos, A.2
O'Day, S.3
Weber, J.S.4
Hamid, O.5
Lebbe, C.6
-
35
-
-
49649114804
-
Phase i safety and pharmacokinetic study of CT-011, a humanized antibody interacting with PD-1, in patients with advanced hematologic malignancies
-
10.1158/1078-0432.CCR-07-4079 18483370 10.1158/1078-0432.CCR-07-4079 1:CAS:528:DC%2BD1cXmtVCmtbw%3D
-
Berger R, Rotem-Yehudar R, Slama G, Landes S, Kneller A, Leiba M, et al. Phase I safety and pharmacokinetic study of CT-011, a humanized antibody interacting with PD-1, in patients with advanced hematologic malignancies. Clin Cancer Res. 2008;14(10):3044-51. doi: 10.1158/1078-0432.CCR-07-4079.
-
(2008)
Clin Cancer Res
, vol.14
, Issue.10
, pp. 3044-3051
-
-
Berger, R.1
Rotem-Yehudar, R.2
Slama, G.3
Landes, S.4
Kneller, A.5
Leiba, M.6
-
36
-
-
77954899030
-
Phase i study of single-agent anti-programmed death-1 (MDX-1106) in refractory solid tumors: Safety, clinical activity, pharmacodynamics, and immunologic correlates
-
10.1200/JCO.2009.26.7609 20516446 10.1200/JCO.2009.26.7609 1:CAS:528:DC%2BC3cXpslajtLw%3D
-
Brahmer JR, Drake CG, Wollner I, Powderly JD, Picus J, Sharfman WH, et al. Phase I study of single-agent anti-programmed death-1 (MDX-1106) in refractory solid tumors: safety, clinical activity, pharmacodynamics, and immunologic correlates. J Clin Oncol. 2010;28(19):3167-75. doi: 10.1200/JCO.2009.26.7609.
-
(2010)
J Clin Oncol
, vol.28
, Issue.19
, pp. 3167-3175
-
-
Brahmer, J.R.1
Drake, C.G.2
Wollner, I.3
Powderly, J.D.4
Picus, J.5
Sharfman, W.H.6
-
37
-
-
84871196652
-
Phase i study of MK-3475 (anti-PD-1 monoclonal antibody) in patients with advanced solid tumors
-
Chicago, IL, June 1-5, Abstract 2512
-
Patnaik A, Kang SP, Tolcher AW, Rasco DW, Papadopoulos KP, Beeram M, et al. Phase I study of MK-3475 (anti-PD-1 monoclonal antibody) in patients with advanced solid tumors. Presented at the American Society of Clinical Oncology, Chicago, IL, June 1-5, 2012. Abstract 2512.
-
(2012)
American Society of Clinical Oncology
-
-
Patnaik, A.1
Kang, S.P.2
Tolcher, A.W.3
Rasco, D.W.4
Papadopoulos, K.P.5
Beeram, M.6
-
38
-
-
84879602789
-
-
Virtual meeting presentation accessed via
-
Virtual meeting presentation accessed via http://www.asco.org/ASCOv2/ MultiMedia/Virtual+Meeting?&vmview=vm-session-presentations-view&confID= 114&sessionID=4763.
-
-
-
-
39
-
-
48649107474
-
Efficacy of everolimus in advanced renal cell carcinoma: A double-blind, randomised, placebo-controlled phase III trial
-
10.1016/S0140-6736(08)61039-9 18653228 10.1016/S0140-6736(08)61039-9 1:CAS:528:DC%2BD1cXps1GmsLY%3D
-
Motzer RJ, Escudier B, Oudard S, Hutson TE, Porta C, Bracarda S, et al. Efficacy of everolimus in advanced renal cell carcinoma: a double-blind, randomised, placebo-controlled phase III trial. Lancet. 2008;372(9637):449-56. doi: 10.1016/S0140-6736(08)61039-9.
-
(2008)
Lancet
, vol.372
, Issue.9637
, pp. 449-456
-
-
Motzer, R.J.1
Escudier, B.2
Oudard, S.3
Hutson, T.E.4
Porta, C.5
Bracarda, S.6
-
40
-
-
82755183572
-
Comparative effectiveness of axitinib versus sorafenib in advanced renal cell carcinoma (AXIS): A randomised phase 3 trial
-
10.1016/S0140-6736(11)61613-9 22056247 10.1016/S0140-6736(11)61613-9 1:CAS:528:DC%2BC3MXhsFGqsL%2FP
-
Rini BI, Escudier B, Tomczak P, Kaprin A, Szczylik C, Hutson TE, et al. Comparative effectiveness of axitinib versus sorafenib in advanced renal cell carcinoma (AXIS): a randomised phase 3 trial. Lancet. 2011;378(9807):1931-9. doi: 10.1016/S0140-6736(11)61613-9.
-
(2011)
Lancet
, vol.378
, Issue.9807
, pp. 1931-1939
-
-
Rini, B.I.1
Escudier, B.2
Tomczak, P.3
Kaprin, A.4
Szczylik, C.5
Hutson, T.E.6
-
41
-
-
27244440177
-
Comparison of outcomes of phase II studies and subsequent randomized control studies using identical chemotherapeutic regimens
-
10.1200/JCO.2005.06.679 16192585 10.1200/JCO.2005.06.679 1:CAS:528:DC%2BD2MXhtFCrsbjF
-
Zia MI, Siu LL, Pond GR, Chen EX. Comparison of outcomes of phase II studies and subsequent randomized control studies using identical chemotherapeutic regimens. J Clin Oncol. 2005;23(28):6982-91. doi: 10.1200/JCO.2005.06.679.
-
(2005)
J Clin Oncol
, vol.23
, Issue.28
, pp. 6982-6991
-
-
Zia, M.I.1
Siu, L.L.2
Pond, G.R.3
Chen, E.X.4
-
42
-
-
63449124514
-
Anti-programmed death-1 synergizes with granulocyte macrophage colony-stimulating factor-secreting tumor cell immunotherapy providing therapeutic benefit to mice with established tumors
-
10.1158/1078-0432.CCR-08-1825 19208793 10.1158/1078-0432.CCR-08-1825 1:CAS:528:DC%2BD1MXisVWrsro%3D
-
Li B, VanRoey M, Wang C, Chen TH, Korman A, Jooss K. Anti-programmed death-1 synergizes with granulocyte macrophage colony-stimulating factor-secreting tumor cell immunotherapy providing therapeutic benefit to mice with established tumors. Clin Cancer Res. 2009;15(5):1623-34. doi: 10.1158/1078-0432.CCR-08-1825.
-
(2009)
Clin Cancer Res
, vol.15
, Issue.5
, pp. 1623-1634
-
-
Li, B.1
Vanroey, M.2
Wang, C.3
Chen, T.H.4
Korman, A.5
Jooss, K.6
-
43
-
-
84857506147
-
Consequence of dose scheduling of sunitinib on host immune response elements and vaccine combination therapy
-
10.1002/ijc.26219 21633954 10.1002/ijc.26219 1:CAS:528: DC%2BC38Xis1Olt7o%3D
-
Farsaci B, Higgins JP, Hodge JW. Consequence of dose scheduling of sunitinib on host immune response elements and vaccine combination therapy. Int J Cancer. 2012;130(8):1948-59. doi: 10.1002/ijc.26219.
-
(2012)
Int J Cancer
, vol.130
, Issue.8
, pp. 1948-1959
-
-
Farsaci, B.1
Higgins, J.P.2
Hodge, J.W.3
-
44
-
-
63549105681
-
Sunitinib mediates reversal of myeloid-derived suppressor cell accumulation in renal cell carcinoma patients
-
10.1158/1078-0432.CCR-08-1332 19276286 10.1158/1078-0432.CCR-08-1332 1:CAS:528:DC%2BD1MXjtF2rurY%3D
-
Ko JS, Zea AH, Rini BI, Ireland JL, Elson P, Cohen P, et al. Sunitinib mediates reversal of myeloid-derived suppressor cell accumulation in renal cell carcinoma patients. Clin Cancer Res. 2009;15(6):2148-57. doi: 10.1158/1078-0432.CCR-08-1332.
-
(2009)
Clin Cancer Res
, vol.15
, Issue.6
, pp. 2148-2157
-
-
Ko, J.S.1
Zea, A.H.2
Rini, B.I.3
Ireland, J.L.4
Elson, P.5
Cohen, P.6
-
45
-
-
78649916060
-
Targeting STAT3 in adoptively transferred T cells promotes their in vivo expansion and antitumor effects
-
10.1158/0008-5472.CAN-10-1293 21118964 10.1158/0008-5472.CAN-10-1293 1:CAS:528:DC%2BC3cXhsFamur3K
-
Kujawski M, Zhang C, Herrmann A, Reckamp K, Scuto A, Jensen M, et al. Targeting STAT3 in adoptively transferred T cells promotes their in vivo expansion and antitumor effects. Cancer Res. 2010;70(23):9599-610. doi: 10.1158/0008-5472.CAN-10-1293.
-
(2010)
Cancer Res
, vol.70
, Issue.23
, pp. 9599-9610
-
-
Kujawski, M.1
Zhang, C.2
Herrmann, A.3
Reckamp, K.4
Scuto, A.5
Jensen, M.6
-
46
-
-
65549141834
-
The novel role of tyrosine kinase inhibitor in the reversal of immune suppression and modulation of tumor microenvironment for immune-based cancer therapies
-
10.1158/0008-5472.CAN-08-4709 19276342 10.1158/0008-5472.CAN-08-4709 1:CAS:528:DC%2BD1MXjtFyqurY%3D
-
Ozao-Choy J, Ma G, Kao J, Wang GX, Meseck M, Sung M, et al. The novel role of tyrosine kinase inhibitor in the reversal of immune suppression and modulation of tumor microenvironment for immune-based cancer therapies. Cancer Res. 2009;69(6):2514-22. doi: 10.1158/0008-5472.CAN-08-4709.
-
(2009)
Cancer Res
, vol.69
, Issue.6
, pp. 2514-2522
-
-
Ozao-Choy, J.1
Ma, G.2
Kao, J.3
Wang, G.X.4
Meseck, M.5
Sung, M.6
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