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Volumn 773, Issue , 2014, Pages 127-142

RB and lamins in cell cycle regulation and aging

Author keywords

A type lamins; Aging; B type lamins; Cancer; Cell cycle progression; Lamins; LMNA gene; p53; Progerin; Retinoblastoma protein; Senescence; Telomeres

Indexed keywords

LAMIN; LAMIN A; LAMIN B; LAMIN B1; LAMIN C; PROTEIN P53; RETINOBLASTOMA PROTEIN; TRANSCRIPTION FACTOR E2F; UNCLASSIFIED DRUG; VON HIPPEL LINDAU PROTEIN;

EID: 84934435900     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-4899-8032-8_6     Document Type: Article
Times cited : (20)

References (94)
  • 1
    • 0018093261 scopus 로고
    • Immunocytochemical localization of the major polypeptides of the nuclear pore complex-lamina fraction. Interphase and mitotic distribution
    • Gerace L, Blum A, Blobel G (1978) Immunocytochemical localization of the major polypeptides of the nuclear pore complex-lamina fraction. Interphase and mitotic distribution. J Cell Biol 79(2 Pt 1):546-566
    • (1978) J Cell Biol , vol.79 , Issue.2 PART 1 , pp. 546-566
    • Gerace, L.1    Blum, A.2    Blobel, G.3
  • 2
    • 84875175486 scopus 로고    scopus 로고
    • When lamins go bad: Nuclear structure and disease
    • Schreiber KH, Kennedy BK (2013) When lamins go bad: nuclear structure and disease. Cell 152(6):1365-1375
    • (2013) Cell , vol.152 , Issue.6 , pp. 1365-1375
    • Schreiber, K.H.1    Kennedy, B.K.2
  • 3
    • 0018840796 scopus 로고
    • The nuclear envelope lamina is reversibly depolymerized during mitosis
    • Gerace L, Blobel G (1980) the nuclear envelope lamina is reversibly depolymerized during mitosis. Cell 19:277-287
    • (1980) Cell , vol.19 , pp. 277-287
    • Gerace, L.1    Blobel, G.2
  • 5
    • 0038376023 scopus 로고    scopus 로고
    • LMNA is mutated in Hutchinson-Gilford progeria (MIM 176670) but not in Wiedemann-Rautenstrauch progeroid syndrome (MIM 264090
    • Cao H, Hegele RA (2003) LMNA is mutated in Hutchinson-Gilford progeria (MIM 176670) but not in Wiedemann-Rautenstrauch progeroid syndrome (MIM 264090). J Hum Genet 48:271-274
    • (2003) J Hum Genet , vol.48 , pp. 271-274
    • Cao, H.1    Hegele, R.A.2
  • 8
    • 77954950116 scopus 로고    scopus 로고
    • Progeria syndromes and ageing: What is the connection?
    • Burtner CR, Kennedy BK (2010) Progeria syndromes and ageing: what is the connection? Nat Rev Mol Cell Biol 11(8):567-578
    • (2010) Nat Rev Mol Cell Biol , vol.11 , Issue.8 , pp. 567-578
    • Burtner, C.R.1    Kennedy, B.K.2
  • 9
    • 81355146839 scopus 로고    scopus 로고
    • Lamin A farnesylation and aging
    • Reddy S, Comai L (2012) Lamin A, farnesylation and aging. Exp Cell Res 318(1):1-7
    • (2012) Exp Cell Res , vol.318 , Issue.1 , pp. 1-7
    • Reddy, S.1    Comai, L.2
  • 10
    • 80052970177 scopus 로고    scopus 로고
    • Quantitative assessment of lactate and progerin production in normal human cutaneous cells during normal ageing: Effect of an Alaria esculenta extract
    • Verdy C, Branka JE, Mekideche N (2011) Quantitative assessment of lactate and progerin production in normal human cutaneous cells during normal ageing: effect of an Alaria esculenta extract. Int J Cosmet Sci 33(5):462-466
    • (2011) Int J Cosmet Sci , vol.33 , Issue.5 , pp. 462-466
    • Verdy, C.1    Branka, J.E.2    Mekideche, N.3
  • 11
    • 41649101975 scopus 로고    scopus 로고
    • The mutant form of lamin A that causes Hutchinson-Gilford progeria is a biomarker of cellular aging in human skin
    • McClintock D, Ratner D, Lokuge M, Owens DM, Gordon LB, Collins FS, Djabali K (2007) The mutant form of lamin A that causes Hutchinson-Gilford progeria is a biomarker of cellular aging in human skin. PLoS One 2(12):e1269
    • (2007) PLoS One , vol.2 , Issue.12
    • McClintock, D.1    Ratner, D.2    Lokuge, M.3    Owens, D.M.4    Gordon, L.B.5    Collins, F.S.6    Djabali, K.7
  • 12
    • 33646745137 scopus 로고    scopus 로고
    • Lamin A-dependent nuclear defects in human aging
    • Scaffi di P, Misteli T (2006) Lamin A-dependent nuclear defects in human aging. Science 312(5776):1059-1063
    • (2006) Science , vol.312 , Issue.5776 , pp. 1059-1063
    • Scaffi Di, P.1    Misteli, T.2
  • 13
    • 43149124203 scopus 로고    scopus 로고
    • Lamin A-dependent misregulation of adult stem cells associated with accelerated ageing
    • Scaffi di P, Misteli T (2008) Lamin A-dependent misregulation of adult stem cells associated with accelerated ageing. Nat Cell Biol 10(4):452-459
    • (2008) Nat Cell Biol , vol.10 , Issue.4 , pp. 452-459
    • Scaffi Di, P.1    Misteli, T.2
  • 15
    • 0024561417 scopus 로고
    • Differential timing of nuclear lamin A/C expression in the various organs of the mouse embryo and the young animal: A developmental study
    • Rober RA, Weber K, Osborn M (1989) Differential timing of nuclear lamin A/C expression in the various organs of the mouse embryo and the young animal: a developmental study. Development 105:365-378
    • (1989) Development , vol.105 , pp. 365-378
    • Rober, R.A.1    Weber, K.2    Osborn, M.3
  • 19
    • 0021916026 scopus 로고
    • V-myc-and c-myc-encoded proteins are associated with the nuclear matrix
    • Eisenman RN, Tachibana CY, Abrams HD, Hann SR (1985) V-myc-and c-myc-encoded proteins are associated with the nuclear matrix. Mol Cell Biol 5(1):114-126
    • (1985) Mol Cell Biol , vol.5 , Issue.1 , pp. 114-126
    • Eisenman, R.N.1    Tachibana, C.Y.2    Abrams, H.D.3    Hann, S.R.4
  • 20
    • 0027976913 scopus 로고
    • The retinoblastoma gene product is a cell cycle-dependent, nuclear matrix-associated protein
    • Mancini MA, Shan B, Nickerson JA, Penman S, Lee WH (1994) The retinoblastoma gene product is a cell cycle-dependent, nuclear matrix-associated protein. Proc Natl Acad Sci USA 91(1):418-422
    • (1994) Proc Natl Acad Sci USA , vol.91 , Issue.1 , pp. 418-422
    • Mancini, M.A.1    Shan, B.2    Nickerson, J.A.3    Penman, S.4    Lee, W.H.5
  • 21
    • 0028064990 scopus 로고
    • Complex formation between Lamin A and the retinoblastoma gene product: Identifi cation of the domain on Lamin A required for its interaction
    • Ozaki T, Saijo M, Murakami K, Enomoto H, Taya Y, Sakiyama S (1994) Complex formation between Lamin A and the retinoblastoma gene product: identifi cation of the domain on Lamin A required for its interaction. Oncogene 9:2649-2653
    • (1994) Oncogene , vol.9 , pp. 2649-2653
    • Ozaki, T.1    Saijo, M.2    Murakami, K.3    Enomoto, H.4    Taya, Y.5    Sakiyama, S.6
  • 22
    • 0026329868 scopus 로고
    • Nonfunctional mutants of the retinoblastoma protein are characterized by defects in phosphorylation, viral oncoprotein association, and nuclear tethering
    • Templeton DJ, Park SH, Lanier L, Weinberg RA (1991) Nonfunctional mutants of the retinoblastoma protein are characterized by defects in phosphorylation, viral oncoprotein association, and nuclear tethering. Proc Natl Acad Sci USA 88:3033-3037
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 3033-3037
    • Templeton, D.J.1    Park, S.H.2    Lanier, L.3    Weinberg, R.A.4
  • 23
    • 0025810049 scopus 로고
    • G1/S phosphorylation of the retinoblastoma protein is associated with altered affi nity for the nuclear compartment
    • Mittnacht S, Weinberg RA (1991) G1/S phosphorylation of the retinoblastoma protein is associated with altered affi nity for the nuclear compartment. Cell 65:381-393
    • (1991) Cell , vol.65 , pp. 381-393
    • Mittnacht, S.1    Weinberg, R.A.2
  • 24
    • 80655140622 scopus 로고    scopus 로고
    • Regulating the levels of key factors in cell cycle and DNA repair: New pathways revealed by lamins
    • Redwood AB, Gonzalez-Suarez I, Gonzalo S (2011) Regulating the levels of key factors in cell cycle and DNA repair: new pathways revealed by lamins. Cell Cycle 10(21):3652-3657
    • (2011) Cell Cycle , vol.10 , Issue.21 , pp. 3652-3657
    • Redwood, A.B.1    Gonzalez-Suarez, I.2    Gonzalo, S.3
  • 32
    • 76449120411 scopus 로고    scopus 로고
    • Lamins: 'Structure goes cycling'
    • Boban M, Braun J, Foisner R (2010) Lamins: 'structure goes cycling'. Biochem Soc Trans 38(Pt 1):301-306
    • (2010) Biochem Soc Trans , vol.38 , Issue.PART 1 , pp. 301-306
    • Boban, M.1    Braun, J.2    Foisner, R.3
  • 33
    • 0022506980 scopus 로고
    • A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma
    • Friend SH, Bernards R, Rogelj S, Weinberg RA, Rapaport JM, Albert DM, Dryja TP (1986) A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma. Nature 323(6089):643-646
    • (1986) Nature , vol.323 , Issue.6089 , pp. 643-646
    • Friend, S.H.1    Bernards, R.2    Rogelj, S.3    Weinberg, R.A.4    Rapaport, J.M.5    Albert, D.M.6    Dryja, T.P.7
  • 34
    • 84876808719 scopus 로고    scopus 로고
    • Molecular mechanisms underlying RB protein function
    • Dick FA, Rubin SM (2013) Molecular mechanisms underlying RB protein function. Nat Rev Mol Cell Biol 14(5):297-306
    • (2013) Nat Rev Mol Cell Biol , vol.14 , Issue.5 , pp. 297-306
    • Dick, F.A.1    Rubin, S.M.2
  • 35
    • 0034964014 scopus 로고    scopus 로고
    • Retinoblastoma protein partners
    • Morris EJ, Dyson N (2001) Retinoblastoma protein partners. Adv Cancer Res 82:1-54
    • (2001) Adv Cancer Res , vol.82 , pp. 1-54
    • Morris, E.J.1    Dyson, N.2
  • 36
    • 1842854443 scopus 로고    scopus 로고
    • Lamin A/C binding protein LAP2a is required for nuclear anchorage of retinoblastoma protein
    • Markiewicz E, Dechat T, Foisner R, Quinlan RA, Hutchison CJ (2002) Lamin A/C binding protein LAP2a is required for nuclear anchorage of retinoblastoma protein. Mol Biol Cell 13:4401-4413
    • (2002) Mol Biol Cell , vol.13 , pp. 4401-4413
    • Markiewicz, E.1    Dechat, T.2    Foisner, R.3    Quinlan, R.A.4    Hutchison, C.J.5
  • 37
    • 33645743546 scopus 로고    scopus 로고
    • Lamina-associated polypeptide 2alpha regulates cell cycle progression and differentiation via the retinoblastoma-E2F pathway
    • Dorner D, Vlcek S, Foeger N, Gajewski A, Makolm C, Gotzmann J, Hutchison CJ, Foisner R (2006) Lamina-associated polypeptide 2alpha regulates cell cycle progression and differentiation via the retinoblastoma-E2F pathway. J Cell Biol 173(1):83-93
    • (2006) J Cell Biol , vol.173 , Issue.1 , pp. 83-93
    • Dorner, D.1    Vlcek, S.2    Foeger, N.3    Gajewski, A.4    Makolm, C.5    Gotzmann, J.6    Hutchison, C.J.7    Foisner, R.8
  • 38
    • 33745838652 scopus 로고    scopus 로고
    • Stabilization of the retinoblastoma protein by A-type nuclear lamins is required for INK4A-mediated cell cycle arrest
    • Nitta RT, Jameson SA, Kudlow BA, Conlan LA, Kennedy BK (2006) Stabilization of the retinoblastoma protein by A-type nuclear lamins is required for INK4A-mediated cell cycle arrest. Mol Cell Biol 26:5360-5372
    • (2006) Mol Cell Biol , vol.26 , pp. 5360-5372
    • Nitta, R.T.1    Jameson, S.A.2    Kudlow, B.A.3    Conlan, L.A.4    Kennedy, B.K.5
  • 40
    • 0033057438 scopus 로고    scopus 로고
    • Bovine papillomavirus E2 protein activates a complex growth-inhibitory program in p53 negative HT-3 cervical carcinoma cells that includes repression of cyclin A and cdc25A phosphatase genes and accumulation of hypophosphorylated retinoblastoma protein
    • Naeger LK, Goodwin EC, Hwang ES, DeFilippis RA, Zhang H, DiMaio D (1999) Bovine papillomavirus E2 protein activates a complex growth-inhibitory program in p53 negative HT-3 cervical carcinoma cells that includes repression of cyclin A and cdc25A phosphatase genes and accumulation of hypophosphorylated retinoblastoma protein. Cell Growth Differ 10(6):413-422
    • (1999) Cell Growth Differ , vol.10 , Issue.6 , pp. 413-422
    • Naeger, L.K.1    Goodwin, E.C.2    Hwang, E.S.3    Defilippis, R.A.4    Zhang, H.5    Dimaio, D.6
  • 43
    • 41449094144 scopus 로고    scopus 로고
    • Evidence that proteasome-dependent degradation of the retinoblastoma protein in cells lacking A-type lamins occurs independently of gankyrin and MDM2
    • Nitta RT, Smith CL, Kennedy BK (2007) Evidence that proteasome-dependent degradation of the retinoblastoma protein in cells lacking A-type lamins occurs independently of gankyrin and MDM2. PLoS One 2(9):e963
    • (2007) PLoS One , vol.2 , Issue.9
    • Nitta, R.T.1    Smith, C.L.2    Kennedy, B.K.3
  • 44
    • 33751255699 scopus 로고    scopus 로고
    • Proteasomemediated degradation of integral inner nuclear membrane protein emerin in fi broblasts lacking A-type lamins
    • Muchir A, Massart C, van Engelen BG, Lammens M, Bonne G, Worman HJ (2006) Proteasomemediated degradation of integral inner nuclear membrane protein emerin in fi broblasts lacking A-type lamins. Biochem Biophys Res Commun 351(4):1011-1017
    • (2006) Biochem Biophys Res Commun , vol.351 , Issue.4 , pp. 1011-1017
    • Muchir, A.1    Massart, C.2    Van Engelen, B.G.3    Lammens, M.4    Bonne, G.5    Worman, H.J.6
  • 45
    • 85027955201 scopus 로고    scopus 로고
    • Lamin misexpression upregulates three distinct ubiquitin ligase systems that degrade ATR kinase in HeLa cells
    • Muralikrishna B, Chaturvedi P, Sinha K, Parnaik VK (2012) Lamin misexpression upregulates three distinct ubiquitin ligase systems that degrade ATR kinase in HeLa cells. Mol Cell Biochem 365(1-2):323-332
    • (2012) Mol Cell Biochem , vol.365 , Issue.1-2 , pp. 323-332
    • Muralikrishna, B.1    Chaturvedi, P.2    Sinha, K.3    Parnaik, V.K.4
  • 46
    • 36849058762 scopus 로고    scopus 로고
    • Deciphering AP-1 function in tumorigenesis: Fra-ternizing on target promoters
    • Verde P, Casalino L, Talotta F, Yaniv M, Weitzman JB (2007) Deciphering AP-1 function in tumorigenesis: fra-ternizing on target promoters. Cell Cycle 6(21):2633-2639
    • (2007) Cell Cycle , vol.6 , Issue.21 , pp. 2633-2639
    • Verde, P.1    Casalino, L.2    Talotta, F.3    Yaniv, M.4    Weitzman, J.B.5
  • 48
    • 58149186768 scopus 로고    scopus 로고
    • Fast regulation of AP-1 activity through interaction of lamin A/C, ERK1/2, and c-Fos at the nuclear envelope
    • Gonzalez JM, Navarro-Puche A, Casar B, Crespo P, Andres V (2008) Fast regulation of AP-1 activity through interaction of lamin A/C, ERK1/2, and c-Fos at the nuclear envelope. J Cell Biol 183(4):653-666
    • (2008) J Cell Biol , vol.183 , Issue.4 , pp. 653-666
    • Gonzalez, J.M.1    Navarro-Puche, A.2    Casar, B.3    Crespo, P.4    Andres, V.5
  • 49
    • 84863066305 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase inhibitor regulation of heart function and fi brosis in cardiomyopathy caused by lamin A/C gene mutation
    • Muchir A, Wu W, Worman HJ (2010) Mitogen-activated protein kinase inhibitor regulation of heart function and fi brosis in cardiomyopathy caused by lamin A/C gene mutation. Trends Cardiovasc Med 20(7):217-221
    • (2010) Trends Cardiovasc Med , vol.20 , Issue.7 , pp. 217-221
    • Muchir, A.1    Wu, W.2    Worman, H.J.3
  • 50
    • 78649658934 scopus 로고    scopus 로고
    • ERK1/2 MAP kinases promote cell cycle entry by rapid, kinase-independent disruption of retinoblastomalamin A complexes
    • Rodriguez J, Calvo F, Gonzalez JM, Casar B, Andres V, Crespo P (2010) ERK1/2 MAP kinases promote cell cycle entry by rapid, kinase-independent disruption of retinoblastomalamin A complexes. J Cell Biol 191(5):967-979
    • (2010) J Cell Biol , vol.191 , Issue.5 , pp. 967-979
    • Rodriguez, J.1    Calvo, F.2    Gonzalez, J.M.3    Casar, B.4    Andres, V.5    Crespo, P.6
  • 51
    • 0030731381 scopus 로고    scopus 로고
    • GST-lamin fusion proteins act as dominant negative mutants in Xenopus egg extract and reveal the function of the lamina in DNA replication
    • Ellis DJ, Jenkins H, Whitfield WG, Hutchison CJ (1997) GST-lamin fusion proteins act as dominant negative mutants in Xenopus egg extract and reveal the function of the lamina in DNA replication. J Cell Sci 110:2507-2518
    • (1997) J Cell Sci , vol.110 , pp. 2507-2518
    • Ellis, D.J.1    Jenkins, H.2    Whitfield, W.G.3    Hutchison, C.J.4
  • 52
    • 0030863126 scopus 로고    scopus 로고
    • Disruption of nuclear lamin organization alters the distribution of replication factors and inhibits DNA synthesis
    • Spann TP, Moir RD, Goldman AE, Stick R, Goldman RD (1997) Disruption of nuclear lamin organization alters the distribution of replication factors and inhibits DNA synthesis. J Cell Biol 136:1201-1212
    • (1997) J Cell Biol , vol.136 , pp. 1201-1212
    • Spann, T.P.1    Moir, R.D.2    Goldman, A.E.3    Stick, R.4    Goldman, R.D.5
  • 53
    • 0034640884 scopus 로고    scopus 로고
    • Disruption of nuclear lamin organization blocks the elongation phase of DNA replication
    • Moir RD, Spann TP, Herrmann H, Goldman RD (2000) Disruption of nuclear lamin organization blocks the elongation phase of DNA replication. J Cell Biol 149:1179-1192
    • (2000) J Cell Biol , vol.149 , pp. 1179-1192
    • Moir, R.D.1    Spann, T.P.2    Herrmann, H.3    Goldman, R.D.4
  • 54
    • 0028247078 scopus 로고
    • Dynamic properties of nuclear lamins: Lamin B is associated with sites of DNA replication
    • Moir RD, Spann TP, Goldman RD (1994) Dynamic properties of nuclear lamins: lamin B is associated with sites of DNA replication. J Cell Biol 125:1201-1212
    • (1994) J Cell Biol , vol.125 , pp. 1201-1212
    • Moir, R.D.1    Spann, T.P.2    Goldman, R.D.3
  • 55
    • 0034669029 scopus 로고    scopus 로고
    • Nuclear organization of DNA replication in primary mammalian cells
    • Kennedy BK, Barbie DA, Classon M, Dyson N, Harlow E (2000) Nuclear organization of DNA replication in primary mammalian cells. Genes Dev 14:2855-2868
    • (2000) Genes Dev , vol.14 , pp. 2855-2868
    • Kennedy, B.K.1    Barbie, D.A.2    Classon, M.3    Dyson, N.4    Harlow, E.5
  • 58
    • 79953047556 scopus 로고    scopus 로고
    • Mitotic defects lead to pervasive aneuploidy and accompany loss of RB1 activity in mouse LmnaDhe dermal fi broblasts
    • Pratt CH, Curtain M, Donahue LR, Shopland LS (2011) Mitotic defects lead to pervasive aneuploidy and accompany loss of RB1 activity in mouse LmnaDhe dermal fi broblasts. PLoS One 6(3):e18065
    • (2011) PLoS One , vol.6 , Issue.3
    • Pratt, C.H.1    Curtain, M.2    Donahue, L.R.3    Shopland, L.S.4
  • 59
    • 84873638532 scopus 로고    scopus 로고
    • Aging, cellular senescence, and cancer
    • Campisi J (2013) Aging, cellular senescence, and cancer. Annu Rev Physiol 75: 685-705
    • (2013) Annu Rev Physiol , vol.75 , pp. 685-705
    • Campisi, J.1
  • 61
    • 34247356070 scopus 로고    scopus 로고
    • A lamin A protein isoform overexpressed in Hutchinson-Gilford progeria syndrome interferes with mitosis in progeria and normal cells
    • Cao K, Capell BC, Erdos MR, Djabali K, Collins FS (2007) A lamin A protein isoform overexpressed in Hutchinson-Gilford progeria syndrome interferes with mitosis in progeria and normal cells. Proc Natl Acad Sci USA 104(12):4949-4954
    • (2007) Proc Natl Acad Sci USA , vol.104 , Issue.12 , pp. 4949-4954
    • Cao, K.1    Capell, B.C.2    Erdos, M.R.3    Djabali, K.4    Collins, F.S.5
  • 64
    • 59449095581 scopus 로고    scopus 로고
    • Suppression of proliferative defects associated with processing-defective lamin A mutants by hTERT or inactivation of p53
    • Kudlow BA, Stanfel MN, Burtner CR, Johnston ED, Kennedy BK (2008) Suppression of proliferative defects associated with processing-defective lamin A mutants by hTERT or inactivation of p53. Mol Biol Cell 19(12):5238-5248
    • (2008) Mol Biol Cell , vol.19 , Issue.12 , pp. 5238-5248
    • Kudlow, B.A.1    Stanfel, M.N.2    Burtner, C.R.3    Johnston, E.D.4    Kennedy, B.K.5
  • 66
    • 0018218409 scopus 로고
    • Osteosarcoma in a patient with Hutchinson-Gilford progeria
    • King CR, Lemmer J, Campbell JR, Atkins AR (1978) Osteosarcoma in a patient with Hutchinson-Gilford progeria. J Med Genet 15(6):481-484
    • (1978) J Med Genet , vol.15 , Issue.6 , pp. 481-484
    • King, C.R.1    Lemmer, J.2    Campbell, J.R.3    Atkins, A.R.4
  • 70
    • 80052784590 scopus 로고    scopus 로고
    • Retinoblastomaindependent regulation of cell proliferation and senescence by the p53-p21 axis in lamin A/C-depleted cells
    • Moiseeva O, Bourdeau V, Vernier M, Dabauvalle MC, Ferbeyre G (2011) Retinoblastomaindependent regulation of cell proliferation and senescence by the p53-p21 axis in lamin A/C-depleted cells. Aging Cell 10(5):789-797
    • (2011) Aging Cell , vol.10 , Issue.5 , pp. 789-797
    • Moiseeva, O.1    Bourdeau, V.2    Vernier, M.3    Dabauvalle, M.C.4    Ferbeyre, G.5
  • 71
    • 84880401934 scopus 로고    scopus 로고
    • Loss of VHL promotes progerin expression, leading to impaired p14/ARF function and suppression of p53 activity
    • Jung YS, Lee SJ, Lee SH, Chung JY, Jung YJ, Hwang SH, Ha NC, Park BJ (2013) Loss of VHL promotes progerin expression, leading to impaired p14/ARF function and suppression of p53 activity. Cell Cycle 12(14)
    • (2013) Cell Cycle , vol.12 , Issue.14
    • Jung, Y.S.1    Lee, S.J.2    Lee, S.H.3    Chung, J.Y.4    Jung, Y.J.5    Hwang, S.H.6    Ha, N.C.7    Park, B.J.8
  • 72
    • 77957663987 scopus 로고    scopus 로고
    • Nurturing the genome: A-type lamins preserve genomic stability
    • Gonzalez-Suarez I, Gonzalo S (2010) Nurturing the genome: A-type lamins preserve genomic stability. Nucleus 1(2):129-135
    • (2010) Nucleus , vol.1 , Issue.2 , pp. 129-135
    • Gonzalez-Suarez, I.1    Gonzalo, S.2
  • 74
    • 0024230284 scopus 로고
    • The binding in vitro of the intermediate fi lament protein vimentin to synthetic oligonucleotides containing telomere sequences
    • Shoeman RL, Wadle S, Scherbarth A, Traub P (1988) The binding in vitro of the intermediate fi lament protein vimentin to synthetic oligonucleotides containing telomere sequences. J Biol Chem 263(35):18744-18749
    • (1988) J Biol Chem , vol.263 , Issue.35 , pp. 18744-18749
    • Shoeman, R.L.1    Wadle, S.2    Scherbarth, A.3    Traub, P.4
  • 75
    • 0026541384 scopus 로고
    • Human telomeres are attached to the nuclear matrix
    • de Lange T (1992) Human telomeres are attached to the nuclear matrix. EMBO J 11(2):717-724
    • (1992) EMBO J , vol.11 , Issue.2 , pp. 717-724
    • De Lange, T.1
  • 76
    • 0029827128 scopus 로고    scopus 로고
    • Structure, subnuclear distribution, and nuclear matrix association of the mammalian telomeric complex
    • Luderus ME, van Steensel B, Chong L, Sibon OC, Cremers FF, de Lange T (1996) Structure, subnuclear distribution, and nuclear matrix association of the mammalian telomeric complex. J Cell Biol 135(4):867-881
    • (1996) J Cell Biol , vol.135 , Issue.4 , pp. 867-881
    • Luderus, M.E.1    Van Steensel, B.2    Chong, L.3    Sibon, O.C.4    Cremers, F.F.5    De Lange, T.6
  • 77
    • 59349105194 scopus 로고    scopus 로고
    • The nuclear lamina promotes telomere aggregation and centromere peripheral localization during senescence of human mesenchymal stem cells
    • Raz V, Vermolen BJ, Garini Y, Onderwater JJ, Mommaas-Kienhuis MA, Koster AJ, Young IT, Tanke H, Dirks RW (2008) The nuclear lamina promotes telomere aggregation and centromere peripheral localization during senescence of human mesenchymal stem cells. J Cell Sci 121(Pt 24):4018-4028
    • (2008) J Cell Sci , vol.121 , Issue.PART 24 , pp. 4018-4028
    • Raz, V.1    Vermolen, B.J.2    Garini, Y.3    Onderwater, J.J.4    Mommaas-Kienhuis, M.A.5    Koster, A.J.6    Young, I.T.7    Tanke, H.8    Dirks, R.W.9
  • 80
    • 25144491542 scopus 로고    scopus 로고
    • Role of Rb family in the epigenetic defi nition of chromatin
    • Gonzalo S, Blasco MA (2005) Role of Rb family in the epigenetic defi nition of chromatin. Cell Cycle 4(6):752-755
    • (2005) Cell Cycle , vol.4 , Issue.6 , pp. 752-755
    • Gonzalo, S.1    Ma, B.2
  • 81
    • 34548827379 scopus 로고    scopus 로고
    • Suv4-20h defi ciency results in telomere elongation and derepression of telomere recombination
    • Benetti R, Gonzalo S, Jaco I, Schotta G, Klatt P, Jenuwein T, Blasco MA (2007) Suv4-20h defi ciency results in telomere elongation and derepression of telomere recombination. J Cell Biol 178(6):925-936
    • (2007) J Cell Biol , vol.178 , Issue.6 , pp. 925-936
    • Benetti, R.1    Gonzalo, S.2    Jaco, I.3    Schotta, G.4    Klatt, P.5    Jenuwein, T.6    Ma, B.7
  • 82
    • 0347988045 scopus 로고    scopus 로고
    • Epigenetic regulation of telomere length in mammalian cells by the Suv39h1 and Suv39h2 histone methyltransferases
    • Garcia-Cao M, O'Sullivan R, Peters AH, Jenuwein T, Blasco MA (2004) Epigenetic regulation of telomere length in mammalian cells by the Suv39h1 and Suv39h2 histone methyltransferases. Nat Genet 36(1):94-99
    • (2004) Nat Genet , vol.36 , Issue.1 , pp. 94-99
    • Garcia-Cao, M.1    O'Sullivan, R.2    Peters, A.H.3    Jenuwein, T.4    Ma, B.5
  • 83
    • 74849107200 scopus 로고    scopus 로고
    • Loss of A-type lamins and genomic instability
    • Gonzalez-Suarez I, Redwood AB, Gonzalo S (2009) Loss of A-type lamins and genomic instability. Cell Cycle 8(23):3860-3865
    • (2009) Cell Cycle , vol.8 , Issue.23 , pp. 3860-3865
    • Gonzalez-Suarez, I.1    Redwood, A.B.2    Gonzalo, S.3
  • 85
    • 77955385716 scopus 로고    scopus 로고
    • Role of progerin-induced telomere dysfunction in HGPS premature cellular senescence
    • Benson EK, Lee SW, Aaronson SA (2010) Role of progerin-induced telomere dysfunction in HGPS premature cellular senescence. J Cell Sci 123(Pt 15):2605-2612
    • (2010) J Cell Sci , vol.123 , Issue.PART 15 , pp. 2605-2612
    • Benson, E.K.1    Lee, S.W.2    Aaronson, S.A.3
  • 87
    • 84866153314 scopus 로고    scopus 로고
    • Oxidative stress alters nuclear shape through lamins dysregulation: A route to senescence
    • Barascu A, Le Chalony C, Pennarun G, Genet D, Zaarour N, Bertrand P (2012) Oxidative stress alters nuclear shape through lamins dysregulation: a route to senescence. Nucleus 3(5):411-417
    • (2012) Nucleus , vol.3 , Issue.5 , pp. 411-417
    • Barascu, A.1    Le Chalony, C.2    Pennarun, G.3    Genet, D.4    Zaarour, N.5    Bertrand, P.6
  • 88
    • 84861673276 scopus 로고    scopus 로고
    • Lamin B1 loss is a senescenceassociated biomarker
    • Freund A, Laberge RM, Demaria M, Campisi J (2012) Lamin B1 loss is a senescenceassociated biomarker. Mol Biol Cell 23(11):2066-2075
    • (2012) Mol Biol Cell , vol.23 , Issue.11 , pp. 2066-2075
    • Freund, A.1    Laberge, R.M.2    Demaria, M.3    Campisi, J.4
  • 91
    • 84857995837 scopus 로고    scopus 로고
    • Oxidative stress induces an ATM-independent senescence pathway through p38 MAPKmediated lamin B1 accumulation
    • Barascu A, Le Chalony C, Pennarun G, Genet D, Imam N, Lopez B, Bertrand P (2012) Oxidative stress induces an ATM-independent senescence pathway through p38 MAPKmediated lamin B1 accumulation. EMBO J 31(5):1080-1094
    • (2012) EMBO J , vol.31 , Issue.5 , pp. 1080-1094
    • Barascu, A.1    Le Chalony, C.2    Pennarun, G.3    Genet, D.4    Imam, N.5    Lopez, B.6    Bertrand, P.7
  • 92
    • 43449107982 scopus 로고    scopus 로고
    • Perturbation of wild-type lamin A metabolism results in a progeroid phenotype
    • Candelario J, Sudhakar S, Navarro S, Reddy S, Comai L (2008) Perturbation of wild-type lamin A metabolism results in a progeroid phenotype. Aging Cell 7(3):355-367
    • (2008) Aging Cell , vol.7 , Issue.3 , pp. 355-367
    • Candelario, J.1    Sudhakar, S.2    Navarro, S.3    Reddy, S.4    Comai, L.5
  • 93
    • 77049308856 scopus 로고
    • Aging: A theory based on free radical and radiation chemistry
    • Harman D (1956) Aging: a theory based on free radical and radiation chemistry. J Gerontol 11:298-300
    • (1956) J Gerontol , vol.11 , pp. 298-300
    • Harman, D.1


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