메뉴 건너뛰기




Volumn 200, Issue 5, 2013, Pages 605-617

Lamin B1 fluctuations have differential effects on cellular proliferation and senescence

Author keywords

[No Author keywords available]

Indexed keywords

LAMIN A; LAMIN B; LAMIN B1; LAMIN C; MESSENGER RNA; MICRORNA; MICRORNA 23A; PROTEIN P53; TELOMERASE; UNCLASSIFIED DRUG;

EID: 84874972344     PISSN: 00219525     EISSN: 15408140     Source Type: Journal    
DOI: 10.1083/jcb.201206121     Document Type: Article
Times cited : (192)

References (48)
  • 1
    • 84857995837 scopus 로고    scopus 로고
    • Oxidative stress induces an ATM-independent senescence pathway through p38 MAPK-mediated lamin B1 accumulation
    • Barascu, A., C. Le Chalony, G. Pennarun, D. Genet, N. Imam, B. Lopez, and P. Bertrand. 2012. Oxidative stress induces an ATM-independent senescence pathway through p38 MAPK-mediated lamin B1 accumulation. EMBO J. 31:1080-1094. http://dx.doi.org/10.1038/emboj.2011.492
    • (2012) EMBO J , vol.31 , pp. 1080-1094
    • Barascu, A.1    Le Chalony, C.2    Pennarun, G.3    Genet, D.4    Imam, N.5    Lopez, B.6    Bertrand, P.7
  • 2
    • 77955385716 scopus 로고    scopus 로고
    • Role of progerin-induced telomere dysfunction in HGPS premature cellular senescence
    • Benson, E.K., S.W. Lee, and S.A. Aaronson. 2010. Role of progerin-induced telomere dysfunction in HGPS premature cellular senescence. J. Cell Sci. 123:2605-2612. http://dx.doi.org/10.1242/jcs.067306
    • (2010) J. Cell Sci. , vol.123 , pp. 2605-2612
    • Benson, E.K.1    Lee, S.W.2    Aaronson, S.A.3
  • 3
    • 2342644879 scopus 로고    scopus 로고
    • Aging of Hutchinson-Gilford progeria syndrome fibroblasts is characterised by hyperproliferation and increased apoptosis
    • Bridger, J.M., and I.R. Kill. 2004. Aging of Hutchinson-Gilford progeria syndrome fibroblasts is characterised by hyperproliferation and increased apoptosis. Exp. Gerontol. 39:717-724. http://dx.doi.org/10.1016/j.exger.2004.02.002
    • (2004) Exp. Gerontol. , vol.39 , pp. 717-724
    • Bridger, J.M.1    Kill, I.R.2
  • 5
    • 33750379023 scopus 로고    scopus 로고
    • The laminopathies: the functional architecture of the nucleus and its contribution to disease
    • Burke, B., and C.L. Stewart. 2006. The laminopathies: the functional architecture of the nucleus and its contribution to disease. Annu. Rev. Genomics Hum. Genet. 7:369-405. http://dx.doi.org/10.1146/annurev.genom.7.080505.115732
    • (2006) Annu. Rev. Genomics Hum. Genet. , vol.7 , pp. 369-405
    • Burke, B.1    Stewart, C.L.2
  • 6
    • 34548186667 scopus 로고    scopus 로고
    • Cellular senescence: when bad things happen to good cells
    • Campisi, J., and F. d'Adda di Fagagna. 2007. Cellular senescence: when bad things happen to good cells. Nat. Rev. Mol. Cell Biol. 8:729-740. http://dx.doi.org/10.1038/nrm2233
    • (2007) Nat. Rev. Mol. Cell Biol. , vol.8 , pp. 729-740
    • Campisi, J.1    d'Adda di Fagagna, F.2
  • 9
    • 82655181488 scopus 로고    scopus 로고
    • Deficiencies in lamin B1 and lamin B2 cause neurodevelopmental defects and distinct nuclear shape abnormalities in neurons
    • Coffinier, C., H.J. Jung, C. Nobumori, S. Chang, Y. Tu, R.H. Barnes II, Y. Yoshinaga, P.J. de Jong, L. Vergnes, K. Reue, et al. 2011. Deficiencies in lamin B1 and lamin B2 cause neurodevelopmental defects and distinct nuclear shape abnormalities in neurons. Mol. Biol. Cell. 22:4683-4693. http://dx.doi.org/10.1091/mbc.E11-06-0504
    • (2011) Mol. Biol. Cell. , vol.22 , pp. 4683-4693
    • Coffinier, C.1    Jung, H.J.2    Nobumori, C.3    Chang, S.4    Tu, Y.5    Barnes, II.R.H.6    Yoshinaga, Y.7    de Jong, P.J.8    Vergnes, L.9    Reue, K.10
  • 13
    • 67349126486 scopus 로고    scopus 로고
    • Telomere length in Hutchinson-Gilford progeria syndrome
    • Decker, M.L., E. Chavez, I. Vulto, and P.M. Lansdorp. 2009. Telomere length in Hutchinson-Gilford progeria syndrome. Mech. Ageing Dev. 130: 377-383. http://dx.doi.org/10.1016/j.mad.2009.03.001
    • (2009) Mech. Ageing Dev. , vol.130 , pp. 377-383
    • Decker, M.L.1    Chavez, E.2    Vulto, I.3    Lansdorp, P.M.4
  • 14
    • 24944460598 scopus 로고    scopus 로고
    • Shelterin: the protein complex that shapes and safeguards human telomeres
    • de Lange, T. 2005. Shelterin: the protein complex that shapes and safeguards human telomeres. Genes Dev. 19:2100-2110. http://dx.doi.org/10.1101/gad.1346005
    • (2005) Genes Dev , vol.19 , pp. 2100-2110
    • de Lange, T.1
  • 16
    • 0033979731 scopus 로고    scopus 로고
    • Human keratinocytes that express hTERT and also bypass a p16(INK4a)-enforced mechanism that limits life span become immortal yet retain normal growth and differentiation characteristics
    • Dickson, M.A., W.C. Hahn, Y. Ino, V. Ronfard, J.Y. Wu, R.A. Weinberg, D.N. Louis, F.P. Li, and J.G. Rheinwald. 2000. Human keratinocytes that express hTERT and also bypass a p16(INK4a)-enforced mechanism that limits life span become immortal yet retain normal growth and differentiation characteristics. Mol. Cell. Biol. 20:1436-1447. http://dx.doi.org/10.1128/MCB.20.4.1436-1447.2000
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 1436-1447
    • Dickson, M.A.1    Hahn, W.C.2    Ino, Y.3    Ronfard, V.4    Wu, J.Y.5    Weinberg, R.A.6    Louis, D.N.7    Li, F.P.8    Rheinwald, J.G.9
  • 18
    • 33645743546 scopus 로고    scopus 로고
    • Lamina-associated polypeptide 2? regulates cell cycle progression and differentiation via the retinoblastoma-E2F pathway
    • Dorner, D., S. Vlcek, N. Foeger, A. Gajewski, C. Makolm, J. Gotzmann, C.J. Hutchison, and R. Foisner. 2006. Lamina-associated polypeptide 2? regulates cell cycle progression and differentiation via the retinoblastoma-E2F pathway. J. Cell Biol. 173:83-93. http://dx.doi.org/10.1083/jcb.200511149
    • (2006) J. Cell Biol. , vol.173 , pp. 83-93
    • Dorner, D.1    Vlcek, S.2    Foeger, N.3    Gajewski, A.4    Makolm, C.5    Gotzmann, J.6    Hutchison, C.J.7    Foisner, R.8
  • 20
    • 84861673276 scopus 로고    scopus 로고
    • Lamin B1 loss is a senescence-associated biomarker
    • Freund, A., R.M. Laberge, M. Demaria, and J. Campisi. 2012. Lamin B1 loss is a senescence-associated biomarker. Mol. Biol. Cell. 23:2066-2075. http://dx.doi.org/10.1091/mbc.E11-10-0884
    • (2012) Mol. Biol. Cell. , vol.23 , pp. 2066-2075
    • Freund, A.1    Laberge, R.M.2    Demaria, M.3    Campisi, J.4
  • 23
    • 0035694237 scopus 로고    scopus 로고
    • Identification of essential genes in cultured mammalian cells using small interfering RNAs
    • Harborth, J., S.M. Elbashir, K. Bechert, T. Tuschl, and K. Weber. 2001. Identification of essential genes in cultured mammalian cells using small interfering RNAs. J. Cell Sci. 114:4557-4565.
    • (2001) J. Cell Sci. , vol.114 , pp. 4557-4565
    • Harborth, J.1    Elbashir, S.M.2    Bechert, K.3    Tuschl, T.4    Weber, K.5
  • 24
    • 78751477191 scopus 로고    scopus 로고
    • Gene silencing by microRNAs: contributions of translational repression and mRNA decay
    • Huntzinger, E., and E. Izaurralde. 2011. Gene silencing by microRNAs: contributions of translational repression and mRNA decay. Nat. Rev. Genet. 12:99-110. http://dx.doi.org/10.1038/nrg2936
    • (2011) Nat. Rev. Genet. , vol.12 , pp. 99-110
    • Huntzinger, E.1    Izaurralde, E.2
  • 26
    • 0033605145 scopus 로고    scopus 로고
    • p53- and ATM-dependent apoptosis induced by telomeres lacking TRF2
    • Karlseder, J., D. Broccoli, Y. Dai, S. Hardy, and T. de Lange. 1999. p53- and ATM-dependent apoptosis induced by telomeres lacking TRF2. Science. 283:1321-1325. http://dx.doi.org/10.1126/science.283.5406.1321
    • (1999) Science , vol.283 , pp. 1321-1325
    • Karlseder, J.1    Broccoli, D.2    Dai, Y.3    Hardy, S.4    de Lange, T.5
  • 27
    • 84455208122 scopus 로고    scopus 로고
    • Mouse B-type lamins are required for proper organogenesis but not by embryonic stem cells
    • Kim, Y., A.A. Sharov, K. McDole, M. Cheng, H. Hao, C.M. Fan, N. Gaiano, M.S. Ko, and Y. Zheng. 2011. Mouse B-type lamins are required for proper organogenesis but not by embryonic stem cells. Science. 334:1706-1710. http://dx.doi.org/10.1126/science.1211222
    • (2011) Science , vol.334 , pp. 1706-1710
    • Kim, Y.1    Sharov, A.A.2    McDole, K.3    Cheng, M.4    Hao, H.5    Fan, C.M.6    Gaiano, N.7    Ko, M.S.8    Zheng, Y.9
  • 28
    • 59449095581 scopus 로고    scopus 로고
    • Suppression of proliferative defects associated with processing-defective lamin A mutants by hTERT or inactivation of p53
    • Kudlow, B.A., M.N. Stanfel, C.R. Burtner, E.D. Johnston, and B.K. Kennedy. 2008. Suppression of proliferative defects associated with processing-defective lamin A mutants by hTERT or inactivation of p53. Mol. Biol. Cell. 19: 5238-5248. http://dx.doi.org/10.1091/mbc.E08-05-0492
    • (2008) Mol. Biol. Cell. , vol.19 , pp. 5238-5248
    • Kudlow, B.A.1    Stanfel, M.N.2    Burtner, C.R.3    Johnston, E.D.4    Kennedy, B.K.5
  • 29
    • 69149102249 scopus 로고    scopus 로고
    • miR- 23 regulation of lamin B1 is crucial for oligodendrocyte development and myelination
    • Lin, S.T., and Y.H. Fu. 2009. miR-23 regulation of lamin B1 is crucial for oligodendrocyte development and myelination. Dis Model Mech. 2:178-188. http://dx.doi.org/10.1242/dmm.001065
    • (2009) Dis Model Mech , vol.2 , pp. 178-188
    • Lin, S.T.1    Fu, Y.H.2
  • 31
    • 59849092583 scopus 로고    scopus 로고
    • Lamin B1 controls oxidative stress responses via Oct-1
    • Malhas, A.N., C.F. Lee, and D.J. Vaux. 2009. Lamin B1 controls oxidative stress responses via Oct-1. J. Cell Biol. 184:45-55. http://dx.doi.org/10.1083/jcb.200804155
    • (2009) J. Cell Biol. , vol.184 , pp. 45-55
    • Malhas, A.N.1    Lee, C.F.2    Vaux, D.J.3
  • 32
    • 0028247078 scopus 로고
    • Dynamic properties of nuclear lamins: lamin B is associated with sites of DNA replication
    • Moir, R.D., M. Montag-Lowy, and R.D. Goldman. 1994. Dynamic properties of nuclear lamins: lamin B is associated with sites of DNA replication. J. Cell Biol. 125:1201-1212. http://dx.doi.org/10.1083/jcb.125.6.1201
    • (1994) J. Cell Biol. , vol.125 , pp. 1201-1212
    • Moir, R.D.1    Montag-Lowy, M.2    Goldman, R.D.3
  • 33
    • 55549086812 scopus 로고    scopus 로고
    • Loss of nucleoplasmic LAP2alpha-lamin A complexes causes erythroid and epidermal progenitor hyperproliferation
    • Naetar, N., B. Korbei, S. Kozlov, M.A. Kerenyi, D. Dorner, R. Kral, I. Gotic, P. Fuchs, T.V. Cohen, R. Bittner, et al. 2008. Loss of nucleoplasmic LAP2alpha-lamin A complexes causes erythroid and epidermal progenitor hyperproliferation. Nat. Cell Biol. 10:1341-1348. http://dx.doi.org/10.1038/ncb1793
    • (2008) Nat. Cell Biol. , vol.10 , pp. 1341-1348
    • Naetar, N.1    Korbei, B.2    Kozlov, S.3    Kerenyi, M.A.4    Dorner, D.5    Kral, R.6    Gotic, I.7    Fuchs, P.8    Cohen, T.V.9    Bittner, R.10
  • 34
    • 77956217121 scopus 로고    scopus 로고
    • Autosomal dominant leukodystrophy caused by lamin B1 duplications a clinical and molecular case study of altered nuclear function and disease
    • Padiath, Q.S., and Y.H. Fu. 2010. Autosomal dominant leukodystrophy caused by lamin B1 duplications a clinical and molecular case study of altered nuclear function and disease. Methods Cell Biol. 98:337-357. http://dx.doi.org/10.1016/S0091-679X(10)98014-X
    • (2010) Methods Cell Biol , vol.98 , pp. 337-357
    • Padiath, Q.S.1    Fu, Y.H.2
  • 37
    • 0024561417 scopus 로고
    • Differential timing of nuclear lamin A/C expression in the various organs of the mouse embryo and the young animal: a developmental study
    • Röber, R.A., K. Weber, and M. Osborn. 1989. Differential timing of nuclear lamin A/C expression in the various organs of the mouse embryo and the young animal: a developmental study. Development. 105:365-378.
    • (1989) Development , vol.105 , pp. 365-378
    • Röber, R.A.1    Weber, K.2    Osborn, M.3
  • 38
    • 17644373758 scopus 로고    scopus 로고
    • Reversal of the cellular phenotype in the premature aging disease Hutchinson-Gilford progeria syndrome
    • Scaffidi, P., and T. Misteli. 2005. Reversal of the cellular phenotype in the premature aging disease Hutchinson-Gilford progeria syndrome. Nat. Med. 11:440-445. http://dx.doi.org/10.1038/nm1204
    • (2005) Nat. Med. , vol.11 , pp. 440-445
    • Scaffidi, P.1    Misteli, T.2
  • 39
    • 0026446686 scopus 로고
    • Identification of a minimal transforming domain of p53: negative dominance through abrogation of sequence-specific DNA binding
    • Shaulian, E., A. Zauberman, D. Ginsberg, and M. Oren. 1992. Identification of a minimal transforming domain of p53: negative dominance through abrogation of sequence-specific DNA binding. Mol. Cell. Biol. 12:5581-5592.
    • (1992) Mol. Cell. Biol. , vol.12 , pp. 5581-5592
    • Shaulian, E.1    Zauberman, A.2    Ginsberg, D.3    Oren, M.4
  • 41
    • 0023646768 scopus 로고
    • Teratocarcinoma stem cells and early mouse embryos contain only a single major lamin polypeptide closely resembling lamin B
    • Stewart, C., and B. Burke. 1987. Teratocarcinoma stem cells and early mouse embryos contain only a single major lamin polypeptide closely resembling lamin B. Cell. 51:383-392. http://dx.doi.org/10.1016/0092-8674(87)90634-9
    • (1987) Cell , vol.51 , pp. 383-392
    • Stewart, C.1    Burke, B.2
  • 43
    • 0042420304 scopus 로고    scopus 로고
    • DNA damage foci at dysfunctional telomeres
    • Takai, H., A. Smogorzewska, and T. de Lange. 2003. DNA damage foci at dysfunctional telomeres. Curr. Biol. 13:1549-1556. http://dx.doi.org/10.1016/S0960-9822(03)00542-6
    • (2003) Curr. Biol. , vol.13 , pp. 1549-1556
    • Takai, H.1    Smogorzewska, A.2    de Lange, T.3
  • 44
    • 43149091675 scopus 로고    scopus 로고
    • The integrity of a lamin-B1-dependent nucleoskeleton is a fundamental determinant of RNA synthesis in human cells
    • Tang, C.W., A. Maya-Mendoza, C. Martin, K. Zeng, S. Chen, D. Feret, S.A. Wilson, and D.A. Jackson. 2008. The integrity of a lamin-B1-dependent nucleoskeleton is a fundamental determinant of RNA synthesis in human cells. J. Cell Sci. 121:1014-1024. http://dx.doi.org/10.1242/jcs.020982
    • (2008) J. Cell Sci. , vol.121 , pp. 1014-1024
    • Tang, C.W.1    Maya-Mendoza, A.2    Martin, C.3    Zeng, K.4    Chen, S.5    Feret, D.6    Wilson, S.A.7    Jackson, D.A.8
  • 45
    • 33645472801 scopus 로고    scopus 로고
    • A mitotic lamin B matrix induced by RanGTP required for spindle assembly
    • Tsai, M.Y., S. Wang, J.M. Heidinger, D.K. Shumaker, S.A. Adam, R.D. Goldman, and Y. Zheng. 2006. A mitotic lamin B matrix induced by RanGTP required for spindle assembly. Science. 311:1887-1893. http://dx.doi.org/10.1126/science.1122771
    • (2006) Science , vol.311 , pp. 1887-1893
    • Tsai, M.Y.1    Wang, S.2    Heidinger, J.M.3    Shumaker, D.K.4    Adam, S.A.5    Goldman, R.D.6    Zheng, Y.7
  • 46
    • 3142696838 scopus 로고    scopus 로고
    • Lamin B1 is required for mouse development and nuclear integrity
    • Vergnes, L., M. Péterfy, M.O. Bergo, S.G. Young, and K. Reue. 2004. Lamin B1 is required for mouse development and nuclear integrity. Proc. Natl. Acad. Sci. USA. 101:10428-10433. http://dx.doi.org/10.1073/pnas.0401424101
    • (2004) Proc. Natl. Acad. Sci. USA. , vol.101 , pp. 10428-10433
    • Vergnes, L.1    Péterfy, M.2    Bergo, M.O.3    Young, S.G.4    Reue, K.5
  • 47
    • 77957263769 scopus 로고    scopus 로고
    • Diseases of the nuclear envelope Cold Spring Harb
    • Worman, H.J., C. Ostlund, and Y. Wang. 2010. Diseases of the nuclear envelope. Cold Spring Harb. Perspect. Biol. 2:a000760. http://dx.doi.org/10.1101/cshperspect.a000760
    • (2010) Perspect. Biol. , vol.2
    • Worman, H.J.1    Ostlund, C.2    Wang, Y.3
  • 48
    • 78650995671 scopus 로고    scopus 로고
    • A human iPSC model of Hutchinson Gilford Progeria reveals vascular smooth muscle and mesenchymal stem cell defects
    • Zhang, J., Q. Lian, G. Zhu, F. Zhou, L. Sui, C. Tan, R.A. Mutalif, R. Navasankari, Y. Zhang, H.F. Tse, et al. 2011. A human iPSC model of Hutchinson Gilford Progeria reveals vascular smooth muscle and mesenchymal stem cell defects. Cell Stem Cell. 8:31-45. http://dx.doi.org/10.1016/j.stem.2010.12.002
    • (2011) Cell Stem Cell , vol.8 , pp. 31-45
    • Zhang, J.1    Lian, Q.2    Zhu, G.3    Zhou, F.4    Sui, L.5    Tan, C.6    Mutalif, R.A.7    Navasankari, R.8    Zhang, Y.9    Tse, H.F.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.