Evidence that proteasome-dependent degradation of the retinoblastoma protein in cells lacking A-type lamins occurs independently of gankyrin and MDM2

PLoS ONE

Volumn 2, Issue 9, 2007, Pages

  Nitta, Ryan T ^a,b   Smith, Catherine L ^a   Kennedy, Brian K ^a  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^b STANFORD UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR 2A; GANKYRIN; LAMIN A; LAMIN C; MESSENGER RNA; ONCOPROTEIN; PROTEASOME; PROTEIN MDM2; RETINOBLASTOMA PROTEIN; UNCLASSIFIED DRUG; GANKYRIN PROTEIN, MOUSE; TRANSCRIPTION FACTOR;

ANIMAL CELL; ARTICLE; CANCER INHIBITION; CELL CYCLE ARREST; CONTROLLED STUDY; FIBROBLAST; GENETIC TRANSFECTION; MOUSE; NONHUMAN; PROTEIN DEGRADATION; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; RNA INTERFERENCE; ANIMAL; CELL CYCLE; CELL LINE; CELL STRAIN 3T3; DRUG EFFECT; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; GENETICS; HUMAN; METABOLISM; MUTATION; PROTEIN BINDING; RETROVIRUS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TUMOR CELL LINE; WESTERN BLOTTING;

ANIMALS; BLOTTING, WESTERN; CELL CYCLE; CELL LINE; CELL LINE, TUMOR; CYCLIN-DEPENDENT KINASE INHIBITOR P16; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; HUMANS; LAMIN TYPE A; MICE; MUTATION; NIH 3T3 CELLS; PROTEIN BINDING; PROTO-ONCOGENE PROTEINS C-MDM2; RETINOBLASTOMA PROTEIN; RETROVIRIDAE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA INTERFERENCE; TRANSCRIPTION FACTORS; TRANSFECTION; TUMOR SUPPRESSOR PROTEIN P14ARF;

EID: 41449094144     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0000963     Document Type: Article

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