Post-natal myogenic and adipogenic developmental:Defects and metabolic impairment upon loss of a-type lamins

Nucleus

Volumn 2, Issue 3, 2011, Pages 195-207

  Kubben, Nard ^a,b   Voncken, Jan Willem ^a   Konings, Gonda ^c   van Weeghel, Michel ^d   van den Hoogenhof, Maarten M G ^e   Gijbels, Marion ^f   van Erk, Arie ^a   Schoonderwoerd, Kees ^g   van den Bosch, Bianca ^a,c   Dahlmans, Vivian ^a   Calis, Chantal ^a,c   Houten, Sander M ^d   Misteli, Tom ^b   Pinto, Yigal M ^e  

^a MAASTRICHT UNIVERSITY MEDICAL CENTER   (Netherlands)

^b NATIONAL CANCER INSTITUTE   (United States)

^c MAASTRICHT UNIVERSITY   (Netherlands)

^d EMMA CHILDREN S HOSPITAL   (Netherlands)

^e UNIVERSITY OF AMSTERDAM   (Netherlands)

^f MAASTRICHT UNIVERSITY   (Netherlands)

^g ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

Cardiac hypertrophy; Differentiation; Knock out mouse; Lamin A; Laminopathies; LMNA; Muscular dystrophy

Indexed keywords

ANGIOTENSIN II; CARNITINE; CREATINE KINASE; CREATININE; GLUCOSE; KI 67 ANTIGEN; LACTIC ACID; LAMIN A; TRANSCRIPTOME; UREA;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CAUSE OF DEATH; CONGENITAL HEART MALFORMATION; CONTROLLED STUDY; CORE TEMPERATURE; CREATINE KINASE BLOOD LEVEL; CREATININE BLOOD LEVEL; DEVELOPMENTAL DISORDER; ELECTROCARDIOGRAPHY; ELECTRON TRANSPORT; EMBRYO; EMBRYO DEVELOPMENT; FATTY ACID OXIDATION; GLUCOSE BLOOD LEVEL; GROWTH RETARDATION; HEART FUNCTION; HEART VENTRICLE CONTRACTILITY; HEART VENTRICLE HYPERTROPHY; KIDNEY FUNCTION; KNOCKOUT MOUSE; LIPID METABOLISM; METABOLIC DISORDER; MOUSE; NONHUMAN; ORGAN WEIGHT; P WAVE; PROTEIN ANALYSIS; PROTEIN DEPLETION; PROTEIN EXPRESSION; QT INTERVAL; QT PROLONGATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA ANALYSIS; RNA ISOLATION; SMOOTH MUSCLE CONTRACTION; TRANSMISSION ELECTRON MICROSCOPY; UREA BLOOD LEVEL; WESTERN BLOTTING;

MUS;

EID: 79960255556     PISSN: 19491034     EISSN: 19491042     Source Type: Journal    
DOI: 10.4161/nucl.2.3.15731     Document Type: Article

References (32)

1. Prather RS, Sims MM, Maul GG, First NL, Schatten G. Nuclear lamin antigens are developmentally regulated during porcine and bovine embryogenesis. Biol Reprod 1989; 41:123-32.
2. Schatten G, Maul GG, Schatten H, Chaly N, Simerly C, Balczon R, et al. Nuclear lamins and peripheral nuclear antigens during fertilization and embryogenesis in mice and sea urchins. Proc Natl Acad Sci USA 1985; 82:4727-31.
3. Stewart C, Burke B. Teratocarcinoma stem cells and early mouse embryos contain only a single major lamin polypeptide closely resembling lamin B. Cell 1987; 51:383-92.
4. Röber RA, Weber K, Osborn M. Differential timing of nuclear lamin A/C expression in the various organs of the mouse embryo and the young animal: a developmental study. Development 1989; 105:365-78.
5. Röber RA, Sauter H, Weber K, Osborn M. Cells of the cellular immune and hemopoietic system of the mouse lack lamins A/C: distinction versus other somatic cells. J Cell Sci 1990; 95:587-98.
6. Constantinescu D, Gray HL, Sammak PJ, Schatten GP, Csoka AB. Lamin A/C expression is a marker of mouse and human embryonic stem cell differentiation. Stem Cells 2006; 24:177-85.
7. Peter M, Nigg EA. Ectopic expression of an A-type lamin does not interfere with differentiation of lamin A-negative embryonal carcinoma cells. J Cell Sci 1991; 100:589-98.
8. Van Berlo JH, Voncken JW, Kubben N, Broers JL, Duisters R, van Leeuwen RE, et al. A-type lamins are essential for TGFbeta1 induced PP2A to dephosphorylate transcription factors. Hum Mol Genet 2005; 14:2839-49.
9. Wu Z, Wu L, Weng D, Xu D, Geng J, Zhao F. Reduced expression of lamin A/C correlates with poor histological differentiation and prognosis in primary gastric carcinoma. J Exp Clin Cancer Res 2009; 28:8.
10. Broers JL, Ramaekers FC, Bonne G, Yaou RB, Hutchison CJ. Nuclear lamins: laminopathies and their role in premature ageing. Physiol Rev 2006; 86:967-1008.
11. Lloyd DJ, Trembath RC, Shackleton S. A novel interaction between lamin A and SREBP1: implications for parial lipodystrophy and other laminopathies. Hum Mol Genet 2002; 11:769-77.
12. Scaffidi P, Misteli T. Lamin A-dependent misregulation of adult stem cells associated with accelerated ageing. Nat Cell Biol 2008; 10:452-9.
13. Capell BC, Collins FS. Human laminopathies: nuclei gone genetically awry. Nat Rev Genet 2006; 7:940-52.
14. Junqueira LC, Bignolas G, Brentani RR. Picrosirius staining plus polarization microscopy, a specific method for collagen detection in tissue sections. Histochem J 1979; 11:447-55.
15. Schroen B, Leenders JJ, van Erk A, Bertrand AT, van Loon M, van Leeuwen RE, et al. Lysosomal integral membrane protein 2 is a novel component of the cardiac intercalated disc and vital for load-induced cardiac myocyte hypertrophy. J Exp Med 2007; 204:1227-35.
16. Pendas AM, Zhou Z, Cadinanos J, Freije JM, Wang J, Hultenby K, et al. Defective prelamin A processing and muscular and adipocyte alterations in Zmpste24 metalloproteinase-deficient mice. Nat Genet 2002; 31:94-9.
17. Costa CC, de Almeida IT, Jakobs C, Poll-The BT, Duran M. Dynamic changes of plasma acylcarnitine levels induced by fasting and sunflower oil challenge test in children. Pediatr Res 1999; 46:440-4.
18. van den Bosch BJ, van den Burg CM, Schoonderwoerd K, Lindsey PJ, Scholte HR, de Coo RF, et al. Regional absence of mitochondria causing energy depletion in the myocardium of muscle LIM protein knockout mice. Cardiovasc Res 2005; 65:411-8.
19. Pegoraro G, Kubben N, Wickert U, Gohler H, Hoffmann K, Misteli T. Ageing-related chromatin defects through loss of the NURD complex. Nat Cell Biol 2009; 11:1261-7.
20. Sullivan T, Escalante-Alcalde D, Bhatt H, Anver M, Bhat N, Nagashima K, et al. Loss of A-type lamin expression compromises nuclear envelope integrity leading to muscular dystrophy. J Cell Biol 1999; 147:913-20.
21. Szlachcic J, Hall WD, Tubau JF, Porter V, Vollmer C, Wollam G, et al. Left ventricular hypertrophy reversal with labetalol and propranolol: a prospective randomized, double-blind study. Cardiovasc Drugs Ther 1990; 4:427-33.
22. Banerjee I, Fuseler JW, Price RL, Borg TK, Baudino TA. Determination of cell types and numbers during cardiac development in the neonatal and adult rat and mouse. Am J Physiol Heart Circ Physiol 2007; 293:1883-91.
23. Hew KW, Keller KA. Postnatal anatomical and functional development of the heart: a species comparison. Birth Defects Res B Dev Reprod Toxicol 2003; 68:309-20.
24. Wu S, Platteau A, Chen S, McNamara G, Whitsett J, Bancalari E. Conditional overexpression of connective tissue growth factor disrupts postnatal lung development. Am J Respir Cell Mol Biol 2009.
25. Soonpaa MH, Kim KK, Pajak L, Franklin M, Field LJ. Cardiomyocyte DNA synthesis and binucleation during murine development. Am J Physiol 1996; 271:2183-9.
26. Gottdiener JS, Gross HA, Henry WL, Borer JS, Ebert MH. Effects of self-induced starvation on cardiac size and function in anorexia nervosa. Circulation 1978; 58:425-33.
27. Pirke KM. Central and peripheral noradrenalin regulation in eating disorders. Psychiatry Res 1996; 62:43-9.
28. Nikolova V, Leimena C, McMahon AC, Tan JC, Chandar S, Jogia D, et al. Defects in nuclear structure and function promote dilated cardiomyopathy in lamin A/C-deficient mice. J Clin Invest 2004; 113:357-69.
29. Cutler DA, Sullivan TS, Marcus-Samuels B, Stewart CL, Reitman ML. Characterization of adiposity and metabolism in Lmna-deficient mice. Biochem Biophys Res Commun 2002; 291:522-7.
30. Bergo MO, Gavino B, Ross J, Schmidt WK, Hong C, Kendall LV, et al. Zmpste24 deficiency in mice causes spontaneous bone fractures, muscle weakness and a prelamin A processing defect. Proc Natl Acad Sci USA 2002; 99:13049-54.
31. Rankin J, Ellard S. The laminopathies: a clinical review. Clin Genet 2006; 70:261-74.
32. Wolf CM, Wang L, Alcalai R, Pizard A, Burgon PG, Ahmad F, et al. Lamin A/C haploinsufficiency causes dilated cardiomyopathy and apoptosis-triggered cardiac conduction system disease. J Mol Cell Cardiol 2008; 44:293-303.