Acetaminophen induces JNK/p38 signaling and activates the caspase-9-3-dependent cell death pathway in human mesenchymal stem cells

International Journal of Molecular Medicine

Volumn 36, Issue 2, 2015, Pages 485-492

  Yiang, Giou Teng ^a,b   Yu, Yung Lung ^c,d   Lin, Ko Ting ^e   Chen, Jen Ni ^e   Chang, Wei Jung ^c   Wei, Chyou Wei ^e  

^a TAIPEI TZU CHI HOSPITAL   (Taiwan)

^b TZU CHI UNIVERSITY   (Taiwan)

^c CHINA MEDICAL UNIVERSITY   (Taiwan)

^d ASIA UNIVERSITY   (Taiwan)

^e HUNGKUANG UNIVERSITY   (Taiwan)

Author keywords

Acetaminophen; c Jun N terminal kinase; Caspase; Human mesenchymal stem cells

Indexed keywords

ASCORBIC ACID; CASPASE 3; CASPASE 9; HYDROGEN PEROXIDE; MITOGEN ACTIVATED PROTEIN KINASE P38; PARACETAMOL; STRESS ACTIVATED PROTEIN KINASE; ANALGESIC AGENT;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DEATH; CELL SURVIVAL; CONTROLLED STUDY; CYTOTOXICITY; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; KIDNEY TUBULE CELL; MESENCHYMAL STEM CELL; NONHUMAN; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION; ANIMAL; CELL LINE; CYTOLOGY; DRUG EFFECTS; KIDNEY TUBULE; MESENCHYMAL STROMA CELL; METABOLISM;

ACETAMINOPHEN; ANALGESICS, NON-NARCOTIC; ANIMALS; CASPASE 3; CASPASE 9; CELL DEATH; CELL LINE; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; KIDNEY TUBULES; MESENCHYMAL STROMAL CELLS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; RATS; SIGNAL TRANSDUCTION;

EID: 84934291403     PISSN: 11073756     EISSN: 1791244X     Source Type: Journal    
DOI: 10.3892/ijmm.2015.2254     Document Type: Article

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