Acetaminophen induced renal injury via oxidative stress and TNF-α production: Therapeutic potential of arjunolic acid

Toxicology

Volumn 268, Issue 1-2, 2010, Pages 8-18

  Ghosh, Jyotirmoy ^a   Das, Joydeep ^a   Manna, Prasenjit ^a   Sil, Parames C ^a  

^a BOSE INSTITUTE   (India)

Author keywords

Acetaminophen; Antioxidant; Nephro toxicity; Nitric oxide; Oxidative stress; Tumor necrosis factor

Indexed keywords

ARJUNOLIC ACID; CASPASE 3; CASPASE 9; CREATININE; CYTOCHROME C; NITRIC OXIDE; NITROGEN; PARACETAMOL; TRITERPENOID; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; UREA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CELL DEATH; CREATININE BLOOD LEVEL; CYTOKINE PRODUCTION; CYTOSOL; DISEASE COURSE; DRUG MECHANISM; DRUG OVERDOSE; DRUG STRUCTURE; ENZYME ACTIVATION; ENZYME RELEASE; KIDNEY CELL; KIDNEY INJURY; LIPID PEROXIDATION; MALE; MITOCHONDRIAL MEMBRANE POTENTIAL; NEPHROTOXICITY; NONHUMAN; OXIDATIVE STRESS; PATHOPHYSIOLOGY; PRIORITY JOURNAL; RAT; RENAL PROTECTION; TOXICOKINETICS; UREA NITROGEN BLOOD LEVEL;

ACETAMINOPHEN; ANIMALS; ENZYME-LINKED IMMUNOSORBENT ASSAY; KIDNEY; LIPID PEROXIDATION; MAGNETIC RESONANCE SPECTROSCOPY; MALE; OXIDATIVE STRESS; RATS; RATS, WISTAR; REACTIVE OXYGEN SPECIES; TRITERPENES; TUMOR NECROSIS FACTOR-ALPHA;

RATTUS;

EID: 74149094986     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tox.2009.11.011     Document Type: Article

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