Nephroprotective effects of Zingiber zerumbet Smith ethyl acetate extract against paracetamol-induced nephrotoxicity and oxidative stress in rats

Journal of Zhejiang University: Science B

Volumn 13, Issue 3, 2012, Pages 176-185

  Abdul Hamid, Zariyantey ^a   Budin, Siti Balkis ^a   Wen Jie, Ng ^a   Hamid, Asmah ^a   Husain, Khairana ^a   Mohamed, Jamaludin ^a  

^a UNIVERSITI KEBANGSAAN MALAYSIA   (Malaysia)

Author keywords

Antioxidant; Nephrotoxicity; Oxidative stress; Paracetamol; Zingiber zerumbet

Indexed keywords

ACETIC ACID ETHYL ESTER; ADVANCED OXIDATION PROTEIN PRODUCT; ANTIOXIDANT; CARBONYL DERIVATIVE; CREATININE; GINGER EXTRACT; GLUTATHIONE; MALONALDEHYDE; PARACETAMOL; PROTECTIVE AGENT; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG; WATER; ZINGIBER ZERUMBET EXTRACT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD LEVEL; CELL DAMAGE; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DOSE RESPONSE; DRUG SCREENING; ENZYME ACTIVITY; HISTOPATHOLOGY; NEPHROTOXICITY; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; RENAL PROTECTION; TISSUE LEVEL; TREATMENT OUTCOME; ZINGIBER; ZINGIBER ZERUMBET;

ACETAMINOPHEN; ACETATES; ACUTE KIDNEY INJURY; ANALGESICS, NON-NARCOTIC; ANIMALS; ANTIOXIDANTS; CREATININE; GLUTATHIONE; MALE; MALONDIALDEHYDE; OXIDATIVE STRESS; PHYTOTHERAPY; PLANT EXTRACTS; RATS; RATS, SPRAGUE-DAWLEY; ZINGIBERACEAE;

RATTUS; ZINGIBER ZERUMBET;

EID: 84863485507     PISSN: 16731581     EISSN: 18621783     Source Type: Journal    
DOI: 10.1631/jzus.B1100133     Document Type: Article

References (40)

1. Abdel-Zaher, A. O., Abdel-Rahman, M. M., Hafez, M. M., Omran, F. M., 2007. Role of nitric oxide and reduced glutathione in the protective effects of aminoguanidine, gadolinium chloride and oleanolic acid against acetaminophen-induced hepatic and renal damage. Toxicology, 234(1-2):124-134. [doi:10.1016/j.tox.2007.02. 014] (Pubitemid 46517830)
2. Abdul, A. B., Abdelwahab, S. I., Al-Zubairi, A. S., Elhassan, M. M., Murali, S. M., 2008. Anticancer and antimicrobial activities of zerumbone from the rhizomes of Zingiber zerumbet. Int. J. Pharmacol., 4(4):301-304. [doi:10.3923/ijp. 2008.301.304]
3. Alderman, C. J., Shah, S., Foreman, J. C., Chain, B. M., Katz, D. R., 2002. The role of advanced oxidation protein products in regulation of dendritic cell function. Free Radic. Biol. Med., 32(5):377-385. [doi:10.1016/S0891-5849 (01) 00735-3] (Pubitemid 34178347)
4. Beyer, W., Fridovich, I., 1987. Assaying for superoxide dis-mutase activity: some large consequences of minor changes in conditions. Anal. Biochem., 161(2):559-566. [doi:10.1016/0003-2697 (87) 90489-1] (Pubitemid 17046011)
5. Blakely, P., McDonald, B. R., 1995. Acute renal failure due to acetaminophen ingestion: a case report and review of the literature. J. Am. Soc. Nephrol., 6(1):48-53.
6. Borne, R. F., 1995. Nonsteroidal Anti-Inflammatory Drugs. In: Foye, W. O., Lemke, T. L., Williams, D. A. (Eds.), Principles of Medicinal Chemistry. Williams & Wilkins, p. 535-580.
7. Boutis, K., Shannon, M., 2001. Nephrotoxicity after acute severe acetaminophen poisoning in adolescents. Clin. Toxicol., 39(5):441-445. [doi:10.1081/CLT-100105413] (Pubitemid 32803391)
8. Brown, R. A., 1968. Hepatic and renal damage with paracetamol overdosage. J. Clin. Pathol., 21(6):793.
9. Carpenter, H. M., Mudge, G. H., 1981. Acetaminophen neph-rotoxicity: studies on renal acetylation and deacetylation. J. Pharmacol. Exp. Ther., 218(1):161-167. (Pubitemid 11033734)
10. Chevion, M., Berenshtein, E., Stadtman, E. R., 2000. Human studies related to protein oxidation: protein carbonyl content as a marker of damage. Free Radic. Res., 11(33):S99-S108. (Pubitemid 32055069)
11. Das, J., Ghosh, J., Manna, P., Sil, P. C., 2010. Taurine protects acetaminophen-induced oxidative damage in mice kidney through APAP urinary excretion and CYP2E1 inactiva-tion. Toxicology, 269(1):24-34. [doi:10.1016/j.tox.2010. 01.003]
12. Dilger, R. N, Baker, D. H., 2007. Oral N-acetyl-L-cysteine is a safe and effective precursor of cysteine. J. Anim. Sci., 85(7):1712-1718. [doi:10.2527/jas.2006-835] (Pubitemid 47146733)
13. Ellman, G. L., 1959. Tissue sulphydryl groups. Arch. Biochem., 82(1):70-77. [doi:10.1016/0003-9861 (59) 90090-6]
14. Esterbauer, H., Cheeseman, K. H., 1990. Determination of aldehydic lipid peroxidation products: malonaldehyde and 4-hydroxynonenal. Meth. Enzymol., 186:407-421. [doi:10.1016/0076-6879 (90) 86134-H] (Pubitemid 20279982)
15. Gunnell, D., Murray, V., Hawton, K., 2000. Use of paracetamol (acetaminophen) for suicide and nonfatal poisoning: worldwide patterns of use and misuse. Suicide Life Threat. Behav., 30(4):313-326. (Pubitemid 32106127)
16. Hart, S. G., Beierschmitt, W. P., Wyand, D. S., Khairallah, E. A., Cohen, S. D., 1994. Acetaminophen nephrotoxicity in CD-1 mice. I. Evidence of a role for in situ activation in selective covalent binding and toxicity. Toxicol. Appl. Pharmacol., 126(2):267-275. [doi:10.1006/taap. 1994. 1116] (Pubitemid 24203193)
17. Hemabarathy, B., Budin, S. B., Feizal, V., 2009. Paracetamol hepatoxicity in rats treated with crude extract of Alpinia galanga. J. Biol. Sci., 9(1):57-62. [doi:10.3923/jbs.2009. 57.62]
18. Huang, G. C., Chien, T. Y., Chen, L. G., Wang, C. C., 2005. Antitumor effects of zerumbone from Zingiber zerumbet in P-388D1 cells in vitro and in vivo. Planta Med., 71(3):219-224. [doi:10.1055/s-2005-837820] (Pubitemid 40476777)
19. Ibrahim, M. Y., Abdul, A. B., Ibrahim, T. A., Abdel Wahab, S. I., Elhassan, M. M., Mohan, S., 2010. Attenuation of cisplatin-induced nephrotoxicity in rats using zerumbone. Afr. J. Biotechnol., 9(28):4434-4441.
20. Jaganath, I. B., Ng, L. T., 2000. Herbs: The Green Pharmacy of Malaysia. Vinpress Sdn. Bhd, Malaysia, p. 95-99.
21. Kaderi, M. G., Habib, M. R., Nikkon, F., Yeasmin, T., Rashid, M. A., Rahman, M. M., Gibbons, S., 2010. Zederone from the rhizomes of Zingiber zerumbet and its antistaphylo-coccal activity. Latin Am. Caribbean Bull. Med. Arom. Plants, 9(1):63-68 (in Spanish).
22. Kaplowitz, N., 2000. Mechanism of liver cell injury. J. Hepatol., 32(S1):39-47. [doi:10.1016/S0168-8278 (00) 80 414-6]
23. Kheradpezhouh, E., Panjehshahin, M. R., Miri, R., Javidnia, K., Noorafshan, A., Monabati, A., Dehpour, A. R., 2010. Curcumin protects rats against acetaminophen-induced hepatorenal damages and shows synergistic activity with N-acetyl cysteine. Eur. J. Pharmacol., 628(1-3):274-281. [doi:10.1016/j.ejphar.2009.11.027]
24. Levine, R. L., Williams, J., Stadtman, E. R., Shacter, E., 1990. Carbonyl assays for determination of oxidatively modified proteins. Meth. Enzymol., 233:346-357. [doi:10. 1016/S0076-6879 (94) 33040-9]
25. Margetis, P. I., Antonelou, M. H., Petropoulos, I. K., Margaritis, L. H., Papassideri, I. S., 2009. Increased protein carbony-lation of red blood cell membrane in diabetic retinopathy. Exp. Mol. Pathol., 87(1):76-82. [doi:10.1016/j.yexmp. 2009.04.001]
26. McMurtry, R. J., Snodgrass, W. R., Mitchell, J. R., 1978. Renal necrosis, glutathione depletion, and covalent binding after acetaminophen. Toxicol. Appl. Pharmacol., 46(1):87-100. [doi:10.1016/0041-008X (78) 90139-4] (Pubitemid 9078802)
27. Mitchell, J. R., McMurtry, R. J., Statham, C. N., Nelson, S. D., 1977. Molecular basis for several drug-induced nephro-pathies. Am. J. Med., 62(4):518-526. [doi:10.1016/0002-9343 (77) 90407-7] (Pubitemid 8081021)
28. Nakamura, Y., Yoshida, C., Murakami, A., Ohigashi, H., Osawa, T., Uchida, K., 2004. Zerumbone, a tropical ginger sesquiterpene, activates phase II drug metabolizing enzymes. FEBS Lett., 572(1-3):245-250. [doi:10.1016/j. febslet.2004.07.042] (Pubitemid 39092543)
29. Nelson, S. D., 1995. Mechanisms of the formation and disposition of reactive metabolites that can cause acute liver injury. Drug Metab. Rev., 27(1-2):147-177.
30. Newton, J. F., Yoshimoto, M., Bernstein, J., Rush, G. F., Hook, J. B., 1983. Acetaminophen nephrotoxicity in the rat. 1. Strain differences in nephrotoxicity and metabolism. Toxicol. Appl. Pharmacol., 69(2):291-306. [doi:10.1016/0041-008X (83) 90311-3] (Pubitemid 13075064)
31. Pietta, P. G., 2000. Flavonoids as antioxidants. J. Nat. Prod., 63(7):1035-1042. [doi:10.1021/np9904509] (Pubitemid 30624503)
32. Placke, M. E., Wyand, D. S., Cohen, S. D., 1987. Extrahepatic lesions induced by acetaminophen in the mouse. Toxicol. Pathol., 15(4):381-387. [doi:10.1177/019262338701500 401] (Pubitemid 18000488)
33. Rashid, R. A., Hawariah, A., Pihie, L., 2005. The antiprolifer-ative effects of Zingiber zerumbet extracts and fractions on the growth of human breast carcinoma cell lines. Malays. J. Pharma. Sci., 3(1):45-52.
34. Ruslay, S., Abas, F., Shaari, K., Zainal, Z., Maulidiani, Sirat, H., Israf, D. A., Lajis, N. H., 2007. Characterization of the components present in the active fractions of health gingers (Curcuma xanthorrhiza and Zingiber zerumbet) by HPLC-DAD-ESIMS. Food Chem., 104(3):1183-1191. [doi:10.1016/j. foodchem.2007.01.067] (Pubitemid 46764472)
35. Saadiah, M. S., Halijah, I., 1995. Zingiberaceae. Proceedings of the National Convention on Herbal Medicine. Forest Research Institute Malaysia, Kuala Lumpur, p. 205-207.
36. Sharifah Sakinah, S. A., Handayani, S. T., Azimahtol, L. P., 2007. Zerumbone induced apoptosis in liver cancer cells via modulation of Bax/Bcl-2 ratio. Cancer Cell Inter., 7(1):4. [doi:10.1186/1475-2867-7-4] (Pubitemid 46605896)
37. Slot, C., 1965. Plasma creatinine determination. A new & specific Jaffe reaction method. Scand. J. Clin. Lab. Invest., 17(4):381-387. [doi:10.3109/00365516509077065]
38. Somchit, M. N., Shukriyah, M. H., 2003. Anti-inflammatory property of ethanol and water extracts of Zingiber ze-rumbet. Ind. J. Pharmacol., 35:181-182. (Pubitemid 36681851)
39. Witko-Sarsat, V., Friedlander, M., Capeillere-Blandin, C., Nguyen-Khoa, T., Nguyen, A. T., Zingraff, J., Jungers, A. T., Descamps-Latscha, B., 1996. Advanced oxidation protein products as a novel marker of oxidative stress in uremia. Kidney Int., 49(5):1304-1313. [doi:10.1038/ki. 1996.186] (Pubitemid 26166404)
40. Yousef, M. I., Omar, S. A., El-Guendi, M. I., Abdelmegid, L. A., 2010. Potential protective effects of quercetin and cur-cumin on paracetamol-induced histological changes, oxidative stress, liver and kidney functions and haema-totoxicity in rat. Food Chem. Toxicol., 48(11):3246-3261. [doi:10.1016/j.fct.2010.08.034]