Lupeol protects against acetaminophen-induced oxidative stress and cell death in rat primary hepatocytes

Food and Chemical Toxicology

Volumn 50, Issue 5, 2012, Pages 1781-1789

  Kumari, Archana ^a   Kakkar, Poonam ^a  

^a CSIR INDIAN INSTITUTE OF TOXICOLOGY RESEARCH   (India)

Author keywords

Acetaminophen; Apoptosis; Cytotoxicity; Lupeol; ROS

Indexed keywords

CASPASE 3; CASPASE 9; GLUTATHIONE; GLUTATHIONE DISULFIDE; LUPEOL; MALONALDEHYDE; PARACETAMOL; PROTEIN BAX; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; SILYMARIN; SUPEROXIDE DISMUTASE;

ANIMAL CELL; ANIMAL CELL CULTURE; APOPTOSIS; ARTICLE; CELL CYCLE; CELL DAMAGE; CELL ISOLATION; CELL MEMBRANE DEPOLARIZATION; CELL PROTECTION; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; DNA DAMAGE; DNA FRAGMENTATION; DRUG CYTOTOXICITY; DRUG EXPOSURE; ENZYME ACTIVATION; FLOW CYTOMETRY; HOMEOSTASIS; LIPID PEROXIDATION; LIVER CELL; MALE; MITOCHONDRIAL MEMBRANE POTENTIAL; NICK END LABELING; NONHUMAN; OXIDATION REDUCTION STATE; OXIDATIVE STRESS; RAT; SIGNAL TRANSDUCTION;

ACETAMINOPHEN; ANIMALS; APOPTOSIS; BLOTTING, WESTERN; FLOW CYTOMETRY; HEPATOCYTES; IN SITU NICK-END LABELING; LIPID PEROXIDATION; MALE; OXIDATIVE STRESS; PENTACYCLIC TRITERPENES; RATS; RATS, WISTAR; REACTIVE OXYGEN SPECIES;

RATTUS;

EID: 84859874739     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2012.02.042     Document Type: Article

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