Gentiana manshurica Kitagawa prevents acetaminophen-induced acute hepatic injury in mice via inhibiting JNK/ERK MAPK pathway

World Journal of Gastroenterology

Volumn 16, Issue 3, 2010, Pages 384-391

  Wang, Ai Yan ^a   Lian, Li Hua ^a   Jiang, Ying Zi ^a   Wu, Yan Ling ^a   Nan, Ji Xing ^a  

^a YANBIAN UNIVERSITY   (China)

Author keywords

Acetaminophen; Caspase 3; Gentiana manshurica Kitagawa; JNK ERK MAPK; Oxidative stress

Indexed keywords

4 HYDROXYNONENAL; ACETYLCYSTEINE; ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; CASPASE 3; DNA NUCLEOTIDYLEXOTRANSFERASE; GENTIANA MANSHURICA EXTRACT; GLUTATHIONE; GLUTATHIONE PEROXIDASE; LIVER PROTECTIVE AGENT; MALONALDEHYDE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 9; MITOGEN ACTIVATED PROTEIN KINASE KINASE 7; PARACETAMOL; PLANT EXTRACT; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; GENTIANA MANSHURICA; IN VIVO STUDY; LIVER CELL; LIVER PROTECTION; LIVER TOXICITY; MALE; MEDICINAL PLANT; MOUSE; NICK END LABELING; NONHUMAN; OXIDATIVE STRESS; SIGNAL TRANSDUCTION; SINGLE DRUG DOSE;

EID: 75349087892     PISSN: 10079327     EISSN: None     Source Type: Journal    
DOI: 10.3748/wjg.v16.i3.384     Document Type: Article

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