-
1
-
-
11144222920
-
Crystal structure of the drug discharge outer membrane protein, OprM, of Pseudomonas aeruginosa-dual modes of membrane anchoring and occluded cavity end
-
Akama, H., Kanemaki, M., Yoshimura, M., Tsukihara, T., Kashiwagi, T., Yoneyama, H., et al. (2004). Crystal structure of the drug discharge outer membrane protein, OprM, of Pseudomonas aeruginosa-dual modes of membrane anchoring and occluded cavity end. J. Biol. Chem. 279, 52816-52819. doi: 10.1074/jbc.C400445200.
-
(2004)
J. Biol. Chem
, vol.279
, pp. 52816-52819
-
-
Akama, H.1
Kanemaki, M.2
Yoshimura, M.3
Tsukihara, T.4
Kashiwagi, T.5
Yoneyama, H.6
-
2
-
-
0036147130
-
Electrophysiological behavior of the TolC channel-tunnel in planar lipid bilayers
-
Andersen, C., Hughes, C., and Koronakis, V. (2002a). Electrophysiological behavior of the TolC channel-tunnel in planar lipid bilayers. J. Membr. Biol. 185, 83-92. doi: 10.1007/s00232-001-0113-2.
-
(2002)
J. Membr. Biol
, vol.185
, pp. 83-92
-
-
Andersen, C.1
Hughes, C.2
Koronakis, V.3
-
3
-
-
0036015627
-
An aspartate ring at the TolC tunnel entrance determines ion selectivity and presents a target for blocking by large cations
-
Andersen, C., Koronakis, E., Hughes, C., and Koronakis, V. (2002b). An aspartate ring at the TolC tunnel entrance determines ion selectivity and presents a target for blocking by large cations. Mol. Microbiol. 44, 1131-1139. doi: 10.1046/j.1365-2958.2002.02898.x.
-
(2002)
Mol. Microbiol
, vol.44
, pp. 1131-1139
-
-
Andersen, C.1
Koronakis, E.2
Hughes, C.3
Koronakis, V.4
-
4
-
-
14644420177
-
Influence of amino acid substitutions in the leader peptide on maturation and secretion of mesentericin Y105 by Leuconostoc mesenteroides
-
Aucher, W., Lacombe, C., Héquet, A., Frère, J., and Berjeaud, J. M. (2005). Influence of amino acid substitutions in the leader peptide on maturation and secretion of mesentericin Y105 by Leuconostoc mesenteroides. J. Bacteriol. 187, 2218-2223. doi: 10.1128/JB.187.6.2218-2223.2005.
-
(2005)
J. Bacteriol
, vol.187
, pp. 2218-2223
-
-
Aucher, W.1
Lacombe, C.2
Héquet, A.3
Frère, J.4
Berjeaud, J.M.5
-
5
-
-
1542286912
-
Antibiotic-sensitive TolC mutants and their suppressors
-
Augustus, A. M., Celaya, T., Husain, F., Humbard, M., and Misra, R. (2004). Antibiotic-sensitive TolC mutants and their suppressors. J. Bacteriol. 186, 1851-1860. doi: 10.1128/JB.186.6.1851-1860.2004.
-
(2004)
J. Bacteriol
, vol.186
, pp. 1851-1860
-
-
Augustus, A.M.1
Celaya, T.2
Husain, F.3
Humbard, M.4
Misra, R.5
-
6
-
-
55249109759
-
Direct metal transfer between periplasmic proteins identifies a bacterial copper chaperone
-
Bagai, I., Rensing, C., Blackburn, N. J., and McEvoy, M. M. (2008). Direct metal transfer between periplasmic proteins identifies a bacterial copper chaperone. Biochemistry 47, 11408-11414. doi: 10.1021/bi801638m.
-
(2008)
Biochemistry
, vol.47
, pp. 11408-11414
-
-
Bagai, I.1
Rensing, C.2
Blackburn, N.J.3
McEvoy, M.M.4
-
7
-
-
84896527881
-
Evidence that the C-terminal region is involved in the stability and functionality of OprM in E. coli
-
Bai, J., Bhagavathi, R., Tran, P., Muzzarelli, K., Wang, D., Fralick, J. A. (2014). Evidence that the C-terminal region is involved in the stability and functionality of OprM in E. coli. Microbiol. Res. 169, 425-431. doi: 10.1016/j.micres.2013.08.006.
-
(2014)
Microbiol. Res
, vol.169
, pp. 425-431
-
-
Bai, J.1
Bhagavathi, R.2
Tran, P.3
Muzzarelli, K.4
Wang, D.5
Fralick, J.A.6
-
8
-
-
77951297882
-
Evidence that the C-terminus of OprM is involved in the assembly of the VceAB-OprM efflux pump
-
Bai, J., Mosley, L., and Fralick, J. A. (2010). Evidence that the C-terminus of OprM is involved in the assembly of the VceAB-OprM efflux pump. FEBS Lett. 584, 1493-1497. doi: 10.1016/j.febslet.2010.02.066.
-
(2010)
FEBS Lett
, vol.584
, pp. 1493-1497
-
-
Bai, J.1
Mosley, L.2
Fralick, J.A.3
-
9
-
-
0035955547
-
Substrate-triggered recruitment of the TolC channel-tunnel during type I export of hemolysin by Escherichia coli
-
Balakrishnan, L., Hughes, C., and Koronakis, V. (2001). Substrate-triggered recruitment of the TolC channel-tunnel during type I export of hemolysin by Escherichia coli. J. Mol. Biol. 313, 501-510. doi: 10.1006/jmbi.2001.5038.
-
(2001)
J. Mol. Biol
, vol.313
, pp. 501-510
-
-
Balakrishnan, L.1
Hughes, C.2
Koronakis, V.3
-
10
-
-
41549158741
-
Assembly and channel opening in a bacterial drug efflux machine
-
Bavro, V. N., Pietras, Z., Furnham, N., Perez-Cano, L., Fernandez-Recio, J., Pei, X. Y., et al. (2008). Assembly and channel opening in a bacterial drug efflux machine. Mol. Cell 30, 114-121. doi: 10.1016/j.molcel.2008.02.015.
-
(2008)
Mol. Cell
, vol.30
, pp. 114-121
-
-
Bavro, V.N.1
Pietras, Z.2
Furnham, N.3
Perez-Cano, L.4
Fernandez-Recio, J.5
Pei, X.Y.6
-
11
-
-
0344405700
-
A specific interaction between the NBD of the ABC-transporter HlyB and a C-terminal fragment of its transport substrate haemolysin A
-
Benabdelhak, H., Kiontke, S., Horn, C., Ernst, R., Blight, M., Holland, I., et al. (2003). A specific interaction between the NBD of the ABC-transporter HlyB and a C-terminal fragment of its transport substrate haemolysin A. J. Mol. Biol. 327, 1169-1179. doi: 10.1016/S0022-2836(03)00204-3.
-
(2003)
J. Mol. Biol
, vol.327
, pp. 1169-1179
-
-
Benabdelhak, H.1
Kiontke, S.2
Horn, C.3
Ernst, R.4
Blight, M.5
Holland, I.6
-
12
-
-
79952967236
-
Structural and metal binding characterization of the C-terminal metallochaperone domain of membrane fusion protein SilB from Cupriavidus metallidurans CH34
-
Bersch, B., Derfoufi, K., De Angelis, F., Auquier, V., Ekende, E. N., Mergeay, M., et al. (2011). Structural and metal binding characterization of the C-terminal metallochaperone domain of membrane fusion protein SilB from Cupriavidus metallidurans CH34. Biochemistry 50, 2194-2204. doi: 10.1021/bi200005k.
-
(2011)
Biochemistry
, vol.50
, pp. 2194-2204
-
-
Bersch, B.1
Derfoufi, K.2
De Angelis, F.3
Auquier, V.4
Ekende, E.N.5
Mergeay, M.6
-
13
-
-
84911484514
-
Multidrug efflux pumps in Gram-negative bacteria and their role in antibiotic resistance
-
Blair, J. M. A., Richmond, G. E., and Piddock, L. J. V. (2014). Multidrug efflux pumps in Gram-negative bacteria and their role in antibiotic resistance. Future Microbiol. 9, 1165-1177. doi: 10.2217/FMB.14.66.
-
(2014)
Future Microbiol
, vol.9
, pp. 1165-1177
-
-
Blair, J.M.A.1
Richmond, G.E.2
Piddock, L.J.V.3
-
14
-
-
84923611351
-
Molecular mechanisms of antibiotic resistance
-
Blair, J. M. A., Webber, M. A., Baylay, A. J., Ogbolu, D. O., and Piddock, L. J. V. (2015). Molecular mechanisms of antibiotic resistance. Nat. Rev. Microbiol. 13, 42-51. doi: 10.1038/nrmicro3380.
-
(2015)
Nat. Rev. Microbiol
, vol.13
, pp. 42-51
-
-
Blair, J.M.A.1
Webber, M.A.2
Baylay, A.J.3
Ogbolu, D.O.4
Piddock, L.J.V.5
-
15
-
-
33748759588
-
Directed evolution of a bacterial efflux pump: adaptation of the E. coli TolC exit duct to the Pseudomonas MexAB translocase
-
Bokma, E., Koronakis, E., Lobedanz, S., Hughes, C., and Koronakis, V. (2006). Directed evolution of a bacterial efflux pump: adaptation of the E. coli TolC exit duct to the Pseudomonas MexAB translocase. FEBS Lett. 580, 5339-5343. doi: 10.1016/j.febslet.2006.09.005.
-
(2006)
FEBS Lett
, vol.580
, pp. 5339-5343
-
-
Bokma, E.1
Koronakis, E.2
Lobedanz, S.3
Hughes, C.4
Koronakis, V.5
-
16
-
-
0038645861
-
Identification of oligomerization and drug-binding domains of the membrane fusion protein EmrA
-
Borges-Walmsley, M., Beauchamp, J., Kelly, S., Jumel, K., Candlish, D., Harding, S., et al. (2003). Identification of oligomerization and drug-binding domains of the membrane fusion protein EmrA. J. Biol. Chem. 278, 12903-12912. doi: 10.1074/jbc.M209457200.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 12903-12912
-
-
Borges-Walmsley, M.1
Beauchamp, J.2
Kelly, S.3
Jumel, K.4
Candlish, D.5
Harding, S.6
-
17
-
-
40349106166
-
An RND-type efflux system in Borrelia burgdorferi is involved in virulence and resistance to antimicrobial compounds
-
Bunikis, I., Denker, K., Ostberg, Y., Andersen, C., Benz, R., and Bergstrom, S. (2008). An RND-type efflux system in Borrelia burgdorferi is involved in virulence and resistance to antimicrobial compounds. PLoS Pathog. 4:e1000009. doi: 10.1371/journal.ppat.1000009.
-
(2008)
PLoS Pathog
, vol.4
-
-
Bunikis, I.1
Denker, K.2
Ostberg, Y.3
Andersen, C.4
Benz, R.5
Bergstrom, S.6
-
18
-
-
0035910272
-
How to untwist an alpha-helix: structural principles of an alpha-helical barrel
-
Calladine, C., Sharff, A., and Luisi, B. (2001). How to untwist an alpha-helix: structural principles of an alpha-helical barrel. J. Mol. Biol. 305, 603-618. doi: 10.1006/jmbi.2000.4320.
-
(2001)
J. Mol. Biol
, vol.305
, pp. 603-618
-
-
Calladine, C.1
Sharff, A.2
Luisi, B.3
-
19
-
-
84908425792
-
Tracking metal ions through a Cu/Ag efflux pump assigns the functional roles of the periplasmic proteins
-
Chacon, K. N., Mealman, T. D., McEvoy, M. M., and Blackburn, N. J. (2014). Tracking metal ions through a Cu/Ag efflux pump assigns the functional roles of the periplasmic proteins. Proc. Natl. Acad. Sci. U.S.A. 111, 15373-15378. doi: 10.1073/pnas.1411475111.
-
(2014)
Proc. Natl. Acad. Sci. U.S.A
, vol.111
, pp. 15373-15378
-
-
Chacon, K.N.1
Mealman, T.D.2
McEvoy, M.M.3
Blackburn, N.J.4
-
20
-
-
84902251736
-
Mechanism and structure of the bacterial type IV secretion systems
-
Christie, P. J., Whitaker, N., and Gonzalez-Rivera, C. (2014). Mechanism and structure of the bacterial type IV secretion systems. Biochim. Biophys. Acta. 1843, 1578-1591. doi: 10.1016/j.bbamcr.2013.12.019.
-
(2014)
Biochim. Biophys. Acta
, vol.1843
, pp. 1578-1591
-
-
Christie, P.J.1
Whitaker, N.2
Gonzalez-Rivera, C.3
-
21
-
-
80054732022
-
Identification of the bacterial protein FtsX as a unique target of chemokine-mediated antimicrobial activity against Bacillus anthracis
-
Crawford, M. A., Lowe, D. E., Fisher, D. J., Stibitz, S., Plaut, R. D., Beaber, J. W., et al. (2011). Identification of the bacterial protein FtsX as a unique target of chemokine-mediated antimicrobial activity against Bacillus anthracis. Proc. Natl. Acad. Sci. U.S.A. 108, 17159-17164. doi: 10.1073/pnas.1108495108.
-
(2011)
Proc. Natl. Acad. Sci. U.S.A
, vol.108
, pp. 17159-17164
-
-
Crawford, M.A.1
Lowe, D.E.2
Fisher, D.J.3
Stibitz, S.4
Plaut, R.D.5
Beaber, J.W.6
-
22
-
-
77954656149
-
Metal-induced conformational changes in ZneB suggest an active role of membrane fusion proteins in efflux resistance systems
-
De Angelis, F., Lee, J. K., O'Connell, J. D. III, Miercke, L. J. W., Verschueren, K. H., Srinivasan, V., et al. (2010). Metal-induced conformational changes in ZneB suggest an active role of membrane fusion proteins in efflux resistance systems. Proc. Natl. Acad. Sci. U.S.A. 107, 11038-11043. doi: 10.1073/pnas.1003908107.
-
(2010)
Proc. Natl. Acad. Sci. U.S.A
, vol.107
, pp. 11038-11043
-
-
De Angelis, F.1
Lee, J.K.2
O'Connell, J.D.3
Miercke, L.J.W.4
Verschueren, K.H.5
Srinivasan, V.6
-
23
-
-
0032799345
-
Physicochemical evidence that Treponema pallidum TroA is a zinc-containing metalloprotein that lacks porin-like structure
-
Deka, R., Lee, Y., Hagman, K., Shevchenko, D., Lingwood, C., Hasemann, C., et al. (1999). Physicochemical evidence that Treponema pallidum TroA is a zinc-containing metalloprotein that lacks porin-like structure. J. Bacteriol. 181, 4420-4423.
-
(1999)
J. Bacteriol
, vol.181
, pp. 4420-4423
-
-
Deka, R.1
Lee, Y.2
Hagman, K.3
Shevchenko, D.4
Lingwood, C.5
Hasemann, C.6
-
24
-
-
0034669176
-
Crystal structure of MalK, the ATPase subunit of the trehalose/maltose ABC transporter of the archaeon Thermococcus litoralis
-
Diederichs, K., Diez, J., Greller, G., Müller, C., Breed, J., Schnell, C., et al. (2000). Crystal structure of MalK, the ATPase subunit of the trehalose/maltose ABC transporter of the archaeon Thermococcus litoralis. EMBO J. 19, 5951-5961. doi: 10.1093/emboj/19.22.5951.
-
(2000)
EMBO J
, vol.19
, pp. 5951-5961
-
-
Diederichs, K.1
Diez, J.2
Greller, G.3
Müller, C.4
Breed, J.5
Schnell, C.6
-
25
-
-
0028318241
-
A family of extracytoplasmic proteins that allow transport of large molecules across the outer membranes of Gram-negative bacteria
-
Dinh, T., Paulsen, I. T., and Saier, M. H. (1994). A family of extracytoplasmic proteins that allow transport of large molecules across the outer membranes of Gram-negative bacteria. J. Bacteriol. 176, 3825-3831.
-
(1994)
J. Bacteriol
, vol.176
, pp. 3825-3831
-
-
Dinh, T.1
Paulsen, I.T.2
Saier, M.H.3
-
26
-
-
84937637657
-
Assembly and operation of bacterial tripartite multidrug efflux pumps
-
Du, D., van Veen, H. W., and Luisi, B. F. (2015). Assembly and operation of bacterial tripartite multidrug efflux pumps. Trends Microbiol. 23, 311-319. doi: 10.1016/j.tim.2015.01.010.
-
(2015)
Trends Microbiol
, vol.23
, pp. 311-319
-
-
Du, D.1
van Veen, H.W.2
Luisi, B.F.3
-
27
-
-
84901254487
-
Structure of the AcrAB-TolC multidrug efflux pump
-
Du, D., Wang, Z., James, N. R., Voss, J. E., Klimont, E., Ohene-Agyei, T., et al. (2014). Structure of the AcrAB-TolC multidrug efflux pump. Nature 509, 512-515. doi: 10.1038/nature13205.
-
(2014)
Nature
, vol.509
, pp. 512-515
-
-
Du, D.1
Wang, Z.2
James, N.R.3
Voss, J.E.4
Klimont, E.5
Ohene-Agyei, T.6
-
28
-
-
85006314889
-
Coupling of remote alternating-access transport mechanisms for protons and substrates in the multidrug efflux pump AcrB
-
Eicher, T., Seeger, M. A., Anselmi, C., Zhou, W., Brandstatter, L., Verrey, F., et al. (2014). Coupling of remote alternating-access transport mechanisms for protons and substrates in the multidrug efflux pump AcrB. Elife 3, e03145. doi: 10.7554/eLife.03145.
-
(2014)
Elife
, vol.3
-
-
Eicher, T.1
Seeger, M.A.2
Anselmi, C.3
Zhou, W.4
Brandstatter, L.5
Verrey, F.6
-
29
-
-
0042838181
-
Chimeric analysis of AcrA function reveals the importance of its C-terminal domain in its interaction with the AcrB multidrug efflux pump
-
Elkins, C., and Nikaido, H. (2003). Chimeric analysis of AcrA function reveals the importance of its C-terminal domain in its interaction with the AcrB multidrug efflux pump. J. Bacteriol. 185, 5349-5356. doi: 10.1128/JB.185.18.5349-5356.2003.
-
(2003)
J. Bacteriol
, vol.185
, pp. 5349-5356
-
-
Elkins, C.1
Nikaido, H.2
-
30
-
-
77949535720
-
Features and development of Coot
-
Emsley, P., Lohkamp, B., Scott, W. G., and Cowtan, K. (2010). Features and development of Coot. Acta Cryst. 66, 486-501. doi: 10.1107/S0907444910007493.
-
(2010)
Acta Cryst
, vol.66
, pp. 486-501
-
-
Emsley, P.1
Lohkamp, B.2
Scott, W.G.3
Cowtan, K.4
-
31
-
-
17644392862
-
The crystal structure of the outer membrane protein VceC from the bacterial pathogen Vibrio cholerae at 1.8 angstrom resolution
-
Federici, L., Du, D., Walas, F., Matsumura, H., Fernandez-Recio, J., McKeegan, K., et al. (2005). The crystal structure of the outer membrane protein VceC from the bacterial pathogen Vibrio cholerae at 1.8 angstrom resolution. J. Biol. Chem. 280, 15307-15314. doi: 10.1074/jbc.M500401200.
-
(2005)
J. Biol. Chem
, vol.280
, pp. 15307-15314
-
-
Federici, L.1
Du, D.2
Walas, F.3
Matsumura, H.4
Fernandez-Recio, J.5
McKeegan, K.6
-
32
-
-
9644281653
-
A model of a transmembrane drug-efflux pump from Gram-negative bacteria
-
Fernandez-Recio, J., Walas, F., Federici, L., Pratap, J., Bavro, V., Miguel, R., et al. (2004). A model of a transmembrane drug-efflux pump from Gram-negative bacteria. FEBS Lett. 578, 5-9. doi: 10.1016/j.febslet.2004.10.097.
-
(2004)
FEBS Lett
, vol.578
, pp. 5-9
-
-
Fernandez-Recio, J.1
Walas, F.2
Federici, L.3
Pratap, J.4
Bavro, V.5
Miguel, R.6
-
33
-
-
0029796966
-
Evidence that TolC is required for functioning of the Mar/AcrAB efflux pump of Escherichia coli
-
Fralick, J. A. (1996). Evidence that TolC is required for functioning of the Mar/AcrAB efflux pump of Escherichia coli. J. Bacteriol. 178, 5803-5805.
-
(1996)
J. Bacteriol
, vol.178
, pp. 5803-5805
-
-
Fralick, J.A.1
-
34
-
-
67649415188
-
The C-terminal domain of AcrA is essential for the assembly and function of the multidrug efflux pump AcrAB-TolC
-
Ge, Q., Yamada, Y., and Zgurskaya, H. (2009). The C-terminal domain of AcrA is essential for the assembly and function of the multidrug efflux pump AcrAB-TolC. J. Bacteriol. 191, 4365-4371. doi: 10.1128/JB.00204-09.
-
(2009)
J. Bacteriol
, vol.191
, pp. 4365-4371
-
-
Ge, Q.1
Yamada, Y.2
Zgurskaya, H.3
-
35
-
-
7644244749
-
Genetic evidence for functional interactions between TolC and AcrA proteins of a major antibiotic efflux pump of Escherichia coli
-
Gerken, H., and Misra, R. (2004). Genetic evidence for functional interactions between TolC and AcrA proteins of a major antibiotic efflux pump of Escherichia coli. Mol. Microbiol. 54, 620-631. doi: 10.1111/j.1365-2958.2004.04301.x.
-
(2004)
Mol. Microbiol
, vol.54
, pp. 620-631
-
-
Gerken, H.1
Misra, R.2
-
36
-
-
34548488713
-
Protein secretion systems and adhesins: the molecular armory of Gram-negative pathogens
-
Gerlach, R. G., and Hensel, M. (2007). Protein secretion systems and adhesins: the molecular armory of Gram-negative pathogens. Int. J. Med. Microbiol. 297, 401-415. doi: 10.1016/j.ijmm.2007.03.017.
-
(2007)
Int. J. Med. Microbiol
, vol.297
, pp. 401-415
-
-
Gerlach, R.G.1
Hensel, M.2
-
37
-
-
84883488849
-
Structure of an atypical periplasmic adaptor from a multidrug efflux pump of the spirochete Borrelia burgdorferi
-
Greene, N. P., Hinchliffe, P., Crow, A., Ababou, A., Hughes, C., and Koronakis, V. (2013). Structure of an atypical periplasmic adaptor from a multidrug efflux pump of the spirochete Borrelia burgdorferi. FEBS Lett. 587, 2984-2988. doi: 10.1016/j.febslet.2013.06.056.
-
(2013)
FEBS Lett
, vol.587
, pp. 2984-2988
-
-
Greene, N.P.1
Hinchliffe, P.2
Crow, A.3
Ababou, A.4
Hughes, C.5
Koronakis, V.6
-
38
-
-
84890280793
-
Transcriptomic and biochemical analyses identify a family of chlorhexidine efflux proteins
-
Hassan, K. A., Jackson, S. M., Penesyan, A., Patching, S. G., Tetu, S. G., Eijkelkamp, B. A., et al. (2013). Transcriptomic and biochemical analyses identify a family of chlorhexidine efflux proteins. Proc. Natl. Acad. Sci. U.S.A. 110, 20254-20259. doi: 10.1073/pnas.1317052110.
-
(2013)
Proc. Natl. Acad. Sci. U.S.A
, vol.110
, pp. 20254-20259
-
-
Hassan, K.A.1
Jackson, S.M.2
Penesyan, A.3
Patching, S.G.4
Tetu, S.G.5
Eijkelkamp, B.A.6
-
39
-
-
84924150331
-
Homologs of the Acinetobacter baumannii AceI transporter represent a new family of bacterial multidrug efflux systems
-
Hassan, K. A., Liu, Q., Henderson, P. J. F., and Paulsen, I. T. (2015). Homologs of the Acinetobacter baumannii AceI transporter represent a new family of bacterial multidrug efflux systems. Mbio 6, e01982-14. doi: 10.1128/mBio.01982-14.
-
(2015)
Mbio
, vol.6
-
-
Hassan, K.A.1
Liu, Q.2
Henderson, P.J.F.3
Paulsen, I.T.4
-
40
-
-
3042838743
-
Structure of the periplasmic component of a bacterial drug efflux pump
-
Higgins, M., Bokma, E., Koronakis, E., Hughes, C., and Koronakis, V. (2004a). Structure of the periplasmic component of a bacterial drug efflux pump. Proc. Natl. Acad. Sci. U.S.A. 101, 9994-9999. doi: 10.1073/pnas.0400375101.
-
(2004)
Proc. Natl. Acad. Sci. U.S.A
, vol.101
, pp. 9994-9999
-
-
Higgins, M.1
Bokma, E.2
Koronakis, E.3
Hughes, C.4
Koronakis, V.5
-
41
-
-
4444252811
-
Structure of the ligand-blocked periplasmic entrance of the bacterial multidrug efflux protein TolC
-
Higgins, M., Eswaran, J., Edwards, P., Schertler, G., Hughes, C., and Koronakis, V. (2004b). Structure of the ligand-blocked periplasmic entrance of the bacterial multidrug efflux protein TolC. J. Mol. Biol. 342, 697-702. doi: 10.1016/j.jmb.2004.07.088.
-
(2004)
J. Mol. Biol
, vol.342
, pp. 697-702
-
-
Higgins, M.1
Eswaran, J.2
Edwards, P.3
Schertler, G.4
Hughes, C.5
Koronakis, V.6
-
42
-
-
84906260304
-
Structure of the periplasmic adaptor protein from a major facilitator superfamily (MFS) multidrug efflux pump
-
Hinchliffe, P., Greene, N. P., Paterson, N. G., Crow, A., Hughes, C., and Koronakis, V. (2014). Structure of the periplasmic adaptor protein from a major facilitator superfamily (MFS) multidrug efflux pump. FEBS Lett. 588, 3147-3153. doi: 10.1016/j.febslet.2014.06.055.
-
(2014)
FEBS Lett
, vol.588
, pp. 3147-3153
-
-
Hinchliffe, P.1
Greene, N.P.2
Paterson, N.G.3
Crow, A.4
Hughes, C.5
Koronakis, V.6
-
43
-
-
84883488809
-
Structure and operation of bacterial tripartite pumps
-
Hinchliffe, P., Symmons, M. F., Hughes, C., and Koronakis, V. (2013). Structure and operation of bacterial tripartite pumps. Annu. Rev. Microbiol. 67, 221-242. doi: 10.1146/annurev-micro-092412-155718.
-
(2013)
Annu. Rev. Microbiol
, vol.67
, pp. 221-242
-
-
Hinchliffe, P.1
Symmons, M.F.2
Hughes, C.3
Koronakis, V.4
-
44
-
-
84867374260
-
Conserved small protein associates with the multidrug efflux pump AcrB and differentially affects antibiotic resistance
-
Hobbs, E. C., Yin, X. F., Paul, B. J., Astarita, J. L., and Storz, G. (2012). Conserved small protein associates with the multidrug efflux pump AcrB and differentially affects antibiotic resistance. Proc. Natl. Acad. Sci. U.S.A. 109, 16696-16701. doi: 10.1073/pnas.1210093109.
-
(2012)
Proc. Natl. Acad. Sci. U.S.A
, vol.109
, pp. 16696-16701
-
-
Hobbs, E.C.1
Yin, X.F.2
Paul, B.J.3
Astarita, J.L.4
Storz, G.5
-
45
-
-
77954189092
-
TolC dependency of multidrug efflux systems in Salmonella enterica serovar Typhimurium
-
Horiyama, T., Yamaguchi, A., and Nishino, K. (2010). TolC dependency of multidrug efflux systems in Salmonella enterica serovar Typhimurium. J. Antimicrob. Chemother. 65, 1372-1376. doi: 10.1093/jac/dkq160.
-
(2010)
J. Antimicrob. Chemother
, vol.65
, pp. 1372-1376
-
-
Horiyama, T.1
Yamaguchi, A.2
Nishino, K.3
-
46
-
-
0030858697
-
Interactions of dedicated export membrane proteins of the colicin V secretion system: CvaA, a member of the membrane fusion protein family, interacts with CvaB and TolC
-
Hwang, J., Zhong, X., and Tai, P. (1997). Interactions of dedicated export membrane proteins of the colicin V secretion system: CvaA, a member of the membrane fusion protein family, interacts with CvaB and TolC. J. Bacteriol. 179, 6264-6270.
-
(1997)
J. Bacteriol
, vol.179
, pp. 6264-6270
-
-
Hwang, J.1
Zhong, X.2
Tai, P.3
-
47
-
-
0346749468
-
pH-induced conformational changes of AcrA, the membrane fusion protein of Escherichia coli multidrug efflux system
-
Ip, H., Stratton, K., Zgurskaya, H., and Liu, J. (2003). pH-induced conformational changes of AcrA, the membrane fusion protein of Escherichia coli multidrug efflux system. J. Biol. Chem. 278, 50474-50482. doi: 10.1074/jbc.M305152200.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 50474-50482
-
-
Ip, H.1
Stratton, K.2
Zgurskaya, H.3
Liu, J.4
-
48
-
-
33644829134
-
Role of the carboxy-terminal region of the outer membrane protein AatA in the export of dispersin from enteroaggregative Escherichia coli
-
Iwashita, M., Nishi, J., Wakimoto, N., Fujiyama, R., Yamamoto, K., Tokuda, K., et al. (2006). Role of the carboxy-terminal region of the outer membrane protein AatA in the export of dispersin from enteroaggregative Escherichia coli. FEMS Microbiol. Lett. 256, 266-272. doi: 10.1111/j.1574-6968.2006.00123.x.
-
(2006)
FEMS Microbiol. Lett
, vol.256
, pp. 266-272
-
-
Iwashita, M.1
Nishi, J.2
Wakimoto, N.3
Fujiyama, R.4
Yamamoto, K.5
Tokuda, K.6
-
49
-
-
84876726390
-
Tripartite efflux pumps: energy is required for dissociation, but not assembly or opening of the outer membrane channel of the pump
-
Janganan, T. K., Bavro, V. N., Zhang, L., Borges-Walmsley, M. I., and Walmsley, A. R. (2013). Tripartite efflux pumps: energy is required for dissociation, but not assembly or opening of the outer membrane channel of the pump. Mol. Microbiol. 88, 590-602. doi: 10.1111/mmi.12211.
-
(2013)
Mol. Microbiol
, vol.88
, pp. 590-602
-
-
Janganan, T.K.1
Bavro, V.N.2
Zhang, L.3
Borges-Walmsley, M.I.4
Walmsley, A.R.5
-
50
-
-
79960663093
-
Evidence for the assembly of a bacterial tripartite multidrug pump with a stoichiometry of 3, 6:3
-
Janganan, T. K., Bavro, V. N., Zhang, L., Matak-Vinkovic, D., Barrera, N. P., Venien-Bryan, C., et al. (2011a). Evidence for the assembly of a bacterial tripartite multidrug pump with a stoichiometry of 3:6:3. J. Biol. Chem. 286, 26900-26912. doi: 10.1074/jbc.M111.246595.
-
(2011)
J. Biol. Chem
, vol.286
, pp. 26900-26912
-
-
Janganan, T.K.1
Bavro, V.N.2
Zhang, L.3
Matak-Vinkovic, D.4
Barrera, N.P.5
Venien-Bryan, C.6
-
51
-
-
79953138720
-
Opening of the outer membrane protein channel in tripartite efflux pumps is induced by interaction with the membrane fusion partner
-
Janganan, T. K., Zhang, L., Bavro, V. N., Matak-Vinkovic, D., Barrera, N. P., Burton, M. F., et al. (2011b). Opening of the outer membrane protein channel in tripartite efflux pumps is induced by interaction with the membrane fusion partner. J. Biol. Chem. 286, 5484-5493. doi: 10.1074/jbc.M110.187658.
-
(2011)
J. Biol. Chem
, vol.286
, pp. 5484-5493
-
-
Janganan, T.K.1
Zhang, L.2
Bavro, V.N.3
Matak-Vinkovic, D.4
Barrera, N.P.5
Burton, M.F.6
-
52
-
-
0033515434
-
Alignment and structure prediction of divergent protein families: periplasmic and outer membrane proteins of bacterial efflux pumps
-
Johnson, J. M., and Church, G. M. (1999). Alignment and structure prediction of divergent protein families: periplasmic and outer membrane proteins of bacterial efflux pumps. J. Mol. Biol. 287, 695-715. doi: 10.1006/jmbi.1999.2630.
-
(1999)
J. Mol. Biol
, vol.287
, pp. 695-715
-
-
Johnson, J.M.1
Church, G.M.2
-
53
-
-
84866386279
-
TolC-dependent secretion of an ankyrin repeat-containing protein of Rickettsia typhi
-
Kaur, S. J., Rahman, M. S., Ammerman, N. C., Beier-Sexton, M., Ceraul, S. M., Gillespie, J. J., et al. (2012). TolC-dependent secretion of an ankyrin repeat-containing protein of Rickettsia typhi. J. Bacteriol. 194, 4920-4932. doi: 10.1128/JB.00793-12.
-
(2012)
J. Bacteriol
, vol.194
, pp. 4920-4932
-
-
Kaur, S.J.1
Rahman, M.S.2
Ammerman, N.C.3
Beier-Sexton, M.4
Ceraul, S.M.5
Gillespie, J.J.6
-
54
-
-
77956524004
-
Functional relationships between the AcrA hairpin tip region and the TolC aperture tip region for the formation of the bacterial tripartite efflux pump AcrAB-TolC
-
Kim, H., Xu, Y., Lee, M., Piao, S., Sim, S., Ha, N., et al. (2010). Functional relationships between the AcrA hairpin tip region and the TolC aperture tip region for the formation of the bacterial tripartite efflux pump AcrAB-TolC. J. Bacteriol. 192, 4498-4503. doi: 10.1128/JB.00334-10.
-
(2010)
J. Bacteriol
, vol.192
, pp. 4498-4503
-
-
Kim, H.1
Xu, Y.2
Lee, M.3
Piao, S.4
Sim, S.5
Ha, N.6
-
55
-
-
84937639148
-
Structure of the tripartite multidrug efflux pump AcrAB-TolC suggests an alternative assembly mode
-
Kim, J., Jeong, H., Song, S., Kim, H., Lee, K., Hyun, J., et al. (2015). Structure of the tripartite multidrug efflux pump AcrAB-TolC suggests an alternative assembly mode. Mol. Cells 38, 180-186. doi: 10.14348/molcells.2015.2277.
-
(2015)
Mol. Cells
, vol.38
, pp. 180-186
-
-
Kim, J.1
Jeong, H.2
Song, S.3
Kim, H.4
Lee, K.5
Hyun, J.6
-
56
-
-
0037523158
-
Membrane topology of ABC-type macrolide antibiotic exporter MacB in Escherichia coli
-
Kobayashi, N., Nishino, K., Hirata, T., and Yamaguchi, A. (2003). Membrane topology of ABC-type macrolide antibiotic exporter MacB in Escherichia coli. FEBS Lett. 546, 241-246. doi: 10.1016/S0014-5793(03)00579-9.
-
(2003)
FEBS Lett
, vol.546
, pp. 241-246
-
-
Kobayashi, N.1
Nishino, K.2
Hirata, T.3
Yamaguchi, A.4
-
57
-
-
3943108216
-
Structure and function of TolC: the bacterial exit duct for proteins and drugs
-
Koronakis, V., Eswaran, J., and Hughes, C. (2004). Structure and function of TolC: the bacterial exit duct for proteins and drugs. Annu. Rev. Biochem. 73, 467-489. doi: 10.1146/annurev.biochem.73.011303.074104.
-
(2004)
Annu. Rev. Biochem
, vol.73
, pp. 467-489
-
-
Koronakis, V.1
Eswaran, J.2
Hughes, C.3
-
58
-
-
0031014882
-
Structure of TolC, the outer membrane component of the bacterial type I efflux system, derived from two-dimensional crystals
-
Koronakis, V., Li, J., Koronakis, E., and Stauffer, K. (1997). Structure of TolC, the outer membrane component of the bacterial type I efflux system, derived from two-dimensional crystals. Mol. Microbiol. 23, 617-626. doi: 10.1046/j.1365-2958.1997.d01-1880.x.
-
(1997)
Mol. Microbiol
, vol.23
, pp. 617-626
-
-
Koronakis, V.1
Li, J.2
Koronakis, E.3
Stauffer, K.4
-
59
-
-
0034702177
-
Crystal structure of the bacterial membrane protein TolC central to multidrug efflux and protein export
-
Koronakis, V., Sharff, A., Koronakis, E., Luisi, B., and Hughes, C. (2000). Crystal structure of the bacterial membrane protein TolC central to multidrug efflux and protein export. Nature 405, 914-919. doi: 10.1038/35016007.
-
(2000)
Nature
, vol.405
, pp. 914-919
-
-
Koronakis, V.1
Sharff, A.2
Koronakis, E.3
Luisi, B.4
Hughes, C.5
-
60
-
-
38749137423
-
Fitting periplasmic membrane fusion proteins to inner membrane transporters: mutations that enable Escherichia coli AcrA to function with Pseudomonas aeruginosa MexB
-
Krishnamoorthy, G., Tikhonova, E. B., and Zgurskaya, H. I. (2008). Fitting periplasmic membrane fusion proteins to inner membrane transporters: mutations that enable Escherichia coli AcrA to function with Pseudomonas aeruginosa MexB. J. Bacteriol. 190, 691-698. doi: 10.1128/JB.01276-07.
-
(2008)
J. Bacteriol
, vol.190
, pp. 691-698
-
-
Krishnamoorthy, G.1
Tikhonova, E.B.2
Zgurskaya, H.I.3
-
61
-
-
79251563176
-
Crystal structure of Escherichia coli CusC, the outer membrane component of a heavy metal efflux pump
-
Kulathila, R., Kulathila, R., Indic, M., and van den Berg, B. (2011). Crystal structure of Escherichia coli CusC, the outer membrane component of a heavy metal efflux pump. PLoS ONE 6:e15610. doi: 10.1371/journal.pone.0015610.
-
(2011)
PLoS ONE
, vol.6
-
-
Kulathila, R.1
Kulathila, R.2
Indic, M.3
van den Berg, B.4
-
62
-
-
84922027031
-
Modulation of bacterial multidrug resistance efflux pumps of the major facilitator superfamily
-
Kumar, S., Mukherjee, M. M., and Varela, M. F. (2013). Modulation of bacterial multidrug resistance efflux pumps of the major facilitator superfamily. Int. J. Bacteriol. 2013, pii: 204141. doi: 10.1155/2013/204141.
-
(2013)
Int. J. Bacteriol
, vol.2013
-
-
Kumar, S.1
Mukherjee, M.M.2
Varela, M.F.3
-
63
-
-
84863712924
-
Membrane fusion proteins of type I secretion system and tripartite efflux pumps share a binding motif for TolC in Gram-negative bacteria
-
Lee, M., Jun, S., Yoon, B., Song, S., Lee, K., and Ha, N. (2012). Membrane fusion proteins of type I secretion system and tripartite efflux pumps share a binding motif for TolC in Gram-negative bacteria. PLoS ONE 7:e40460. doi: 10.1371/journal.pone.0040460.
-
(2012)
PLoS ONE
, vol.7
-
-
Lee, M.1
Jun, S.2
Yoon, B.3
Song, S.4
Lee, K.5
Ha, N.6
-
64
-
-
84891826713
-
Crystal structures of CusC review conformational changes accompanying folding and transmembrane channel formation
-
Lei, H., Bolla, J. R., Bishop, N. R., Su, C., and Yu, E. W. (2014a). Crystal structures of CusC review conformational changes accompanying folding and transmembrane channel formation. J. Mol. Biol. 426, 403-411. doi: 10.1016/j.jmb.2013.09.042.
-
(2014)
J. Mol. Biol
, vol.426
, pp. 403-411
-
-
Lei, H.1
Bolla, J.R.2
Bishop, N.R.3
Su, C.4
Yu, E.W.5
-
65
-
-
84902532049
-
Crystal structure of the open state of the Neisseria gonorrhoeae MtrE outer membrane channel
-
Lei, H., Chou, T., Su, C., Bolla, J. R., Kumar, N., Radhakrishnan, A., et al. (2014b). Crystal structure of the open state of the Neisseria gonorrhoeae MtrE outer membrane channel. PLoS ONE 9:e97475. doi: 10.1371/journal.pone.0097475.
-
(2014)
PLoS ONE
, vol.9
-
-
Lei, H.1
Chou, T.2
Su, C.3
Bolla, J.R.4
Kumar, N.5
Radhakrishnan, A.6
-
66
-
-
68949110351
-
Efflux-mediated drug resistance in bacteria: an update
-
Li, X., and Nikaido, H. (2009). Efflux-mediated drug resistance in bacteria: an update. Drugs 69, 1555-1623. doi: 10.2165/11317030-000000000-00000.
-
(2009)
Drugs
, vol.69
, pp. 1555-1623
-
-
Li, X.1
Nikaido, H.2
-
67
-
-
59449104154
-
MacB ABC transporter is a dimer whose ATPase activity and macrolide-binding capacity are regulated by the membrane fusion protein MacA
-
Lin, H. T., Bavro, V. N., Barrera, N. P., Frankish, H. M., Velamakanni, S., van Veen, H. W., et al. (2009). MacB ABC transporter is a dimer whose ATPase activity and macrolide-binding capacity are regulated by the membrane fusion protein MacA. J. Biol. Chem. 284, 1145-1154. doi: 10.1074/jbc.M806964200.
-
(2009)
J. Biol. Chem
, vol.284
, pp. 1145-1154
-
-
Lin, H.T.1
Bavro, V.N.2
Barrera, N.P.3
Frankish, H.M.4
Velamakanni, S.5
van Veen, H.W.6
-
68
-
-
34248359106
-
A periplasmic coiled-coil interface underlying TolC recruitment and the assembly of bacterial drug efflux pumps
-
Lobedanz, S., Bokma, E., Symmons, M. F., Koronakis, E., Hughes, C., and Koronakis, V. (2007). A periplasmic coiled-coil interface underlying TolC recruitment and the assembly of bacterial drug efflux pumps. Proc. Natl. Acad. Sci. U.S.A. 104, 4612-4617. doi: 10.1073/pnas.0610160104.
-
(2007)
Proc. Natl. Acad. Sci. U.S.A
, vol.104
, pp. 4612-4617
-
-
Lobedanz, S.1
Bokma, E.2
Symmons, M.F.3
Koronakis, E.4
Hughes, C.5
Koronakis, V.6
-
69
-
-
23244451021
-
A novel copper-binding fold for the periplasmic copper resistance protein CusF
-
Loftin, I., Franke, S., Roberts, S., Weichsel, A., Heroux, A., Montfort, W., et al. (2005). A novel copper-binding fold for the periplasmic copper resistance protein CusF. Biochemistry 44, 10533-10540. doi: 10.1021/bi050827b.
-
(2005)
Biochemistry
, vol.44
, pp. 10533-10540
-
-
Loftin, I.1
Franke, S.2
Roberts, S.3
Weichsel, A.4
Heroux, A.5
Montfort, W.6
-
70
-
-
77957141422
-
Crystal structures of the CusA efflux pump suggest methionine-mediated metal transport
-
Long, F., Su, C., Zimmermann, M. T., Boyken, S. E., Rajashankar, K. R., Jernigan, R. L., et al. (2010). Crystal structures of the CusA efflux pump suggest methionine-mediated metal transport. Nature 467, 484-488. doi: 10.1038/nature09395.
-
(2010)
Nature
, vol.467
, pp. 484-488
-
-
Long, F.1
Su, C.2
Zimmermann, M.T.3
Boyken, S.E.4
Rajashankar, K.R.5
Jernigan, R.L.6
-
71
-
-
84886032478
-
MacA, a periplasmic membrane fusion protein of the macrolide transporter MacAB-TolC, binds lipopolysaccharide core specifically and with high affinity
-
Lu, S., and Zgurskaya, H. I. (2013). MacA, a periplasmic membrane fusion protein of the macrolide transporter MacAB-TolC, binds lipopolysaccharide core specifically and with high affinity. J. Bacteriol. 195, 4865-4872. doi: 10.1128/JB.00756-13.
-
(2013)
J. Bacteriol
, vol.195
, pp. 4865-4872
-
-
Lu, S.1
Zgurskaya, H.I.2
-
72
-
-
79953171122
-
Interactions between CusF and CusB identified by NMR spectroscopy and chemical cross-linking coupled to mass spectrometry
-
Mealman, T. D., Bagai, I., Singh, P., Goodlett, D. R., Rensing, C., Zhou, H., et al. (2011). Interactions between CusF and CusB identified by NMR spectroscopy and chemical cross-linking coupled to mass spectrometry. Biochemistry 50, 2559-2566. doi: 10.1021/bi102012j.
-
(2011)
Biochemistry
, vol.50
, pp. 2559-2566
-
-
Mealman, T.D.1
Bagai, I.2
Singh, P.3
Goodlett, D.R.4
Rensing, C.5
Zhou, H.6
-
73
-
-
84867520883
-
N-terminal region of CusB is sufficient for metal binding and metal transfer with the metallochaperone CusF
-
Mealman, T. D., Zhou, M., Affandi, T., Chacon, K. N., Aranguren, M. E., Blackburn, N. J., et al. (2012). N-terminal region of CusB is sufficient for metal binding and metal transfer with the metallochaperone CusF. Biochemistry 51, 6767-6775. doi: 10.1021/bi300596a.
-
(2012)
Biochemistry
, vol.51
, pp. 6767-6775
-
-
Mealman, T.D.1
Zhou, M.2
Affandi, T.3
Chacon, K.N.4
Aranguren, M.E.5
Blackburn, N.J.6
-
74
-
-
33644833626
-
Conformational flexibility in the multidrug efflux system protein AcrA
-
Mikolosko, J., Bobyk, K., Zgurskaya, H. I., and Ghosh, P. (2006). Conformational flexibility in the multidrug efflux system protein AcrA. Structure 14, 577-587. doi: 10.1016/j.str.2005.11.015.
-
(2006)
Structure
, vol.14
, pp. 577-587
-
-
Mikolosko, J.1
Bobyk, K.2
Zgurskaya, H.I.3
Ghosh, P.4
-
75
-
-
35648995411
-
Identification and characterization of TriABC-OpmH, a triclosan efflux pump of Pseudomonas aeruginosa requiring two membrane fusion proteins
-
Mima, T., Joshi, S., Gomez-Escalada, M., and Schweizer, H. P. (2007). Identification and characterization of TriABC-OpmH, a triclosan efflux pump of Pseudomonas aeruginosa requiring two membrane fusion proteins. J. Bacteriol. 189, 7600-7609. doi: 10.1128/JB.00850-07.
-
(2007)
J. Bacteriol
, vol.189
, pp. 7600-7609
-
-
Mima, T.1
Joshi, S.2
Gomez-Escalada, M.3
Schweizer, H.P.4
-
76
-
-
84902327129
-
Protein export through the bacterial flagellar type III export pathway
-
Minamino, T. (2014). Protein export through the bacterial flagellar type III export pathway. Biochim. Biophys. Acta 1843, 1642-1648. doi: 10.1016/j.bbamcr.2013.09.005.
-
(2014)
Biochim. Biophys. Acta
, vol.1843
, pp. 1642-1648
-
-
Minamino, T.1
-
77
-
-
64649089196
-
Assembly and transport mechanism of tripartite drug efflux systems
-
Misra, R., and Bavro, V. N. (2009). Assembly and transport mechanism of tripartite drug efflux systems. Biochim. Biophys. Acta 1794, 817-825. doi: 10.1016/j.bbapap.2009.02.017.
-
(2009)
Biochim. Biophys. Acta
, vol.1794
, pp. 817-825
-
-
Misra, R.1
Bavro, V.N.2
-
78
-
-
80051565072
-
The periplasmic membrane proximal domain of MacA acts as a switch in stimulation of ATP hydrolysis by MacB transporter
-
Modali, S. D., and Zgurskaya, H. I. (2011). The periplasmic membrane proximal domain of MacA acts as a switch in stimulation of ATP hydrolysis by MacB transporter. Mol. Microbiol. 81, 937-951. doi: 10.1111/j.1365-2958.2011.07744.x.
-
(2011)
Mol. Microbiol
, vol.81
, pp. 937-951
-
-
Modali, S.D.1
Zgurskaya, H.I.2
-
79
-
-
0037057652
-
Crystal structure of bacterial multidrug efflux transporter AcrB
-
Murakami, S., Nakashima, R., Yamashita, E., and Yamaguchi, A. (2002). Crystal structure of bacterial multidrug efflux transporter AcrB. Nature 419, 587-593. doi: 10.1038/nature01050.
-
(2002)
Nature
, vol.419
, pp. 587-593
-
-
Murakami, S.1
Nakashima, R.2
Yamashita, E.3
Yamaguchi, A.4
-
80
-
-
0027479161
-
Ob(oligonucleotide oligosaccharide binding)-fold-common structural and functional solution for non-homologous sequences
-
Murzin, A. (1993). Ob(oligonucleotide oligosaccharide binding)-fold-common structural and functional solution for non-homologous sequences. EMBO J. 12, 861-867.
-
(1993)
EMBO J
, vol.12
, pp. 861-867
-
-
Murzin, A.1
-
81
-
-
34548491825
-
Assembly of the MexAB-OprM multidrug pump of Pseudomonas aeruginosa: component interactions defined by the study of pump mutant suppressors
-
Nehme, D., and Poole, K. (2007). Assembly of the MexAB-OprM multidrug pump of Pseudomonas aeruginosa: component interactions defined by the study of pump mutant suppressors. J. Bacteriol. 189, 6118-6127. doi: 10.1128/JB.00718-07.
-
(2007)
J. Bacteriol
, vol.189
, pp. 6118-6127
-
-
Nehme, D.1
Poole, K.2
-
82
-
-
84856729230
-
Broad-specificity efflux pumps and their role in multidrug resistance of Gram-negative bacteria
-
Nikaido, H., and Pagès, J. (2012). Broad-specificity efflux pumps and their role in multidrug resistance of Gram-negative bacteria. FEMS Microbiol. Rev. 36, 340-363. doi: 10.1111/j.1574-6976.2011.00290.x.
-
(2012)
FEMS Microbiol. Rev
, vol.36
, pp. 340-363
-
-
Nikaido, H.1
Pagès, J.2
-
83
-
-
0242664748
-
The export of coat protein from enteroaggregative Escherichia coli by a specific ATP-binding cassette transporter system
-
Nishi, J., Sheikh, J., Mizuguchi, K., Luisi, B., Burland, V., Boutin, A., et al. (2003). The export of coat protein from enteroaggregative Escherichia coli by a specific ATP-binding cassette transporter system. J. Biol. Chem. 278, 45680-45689. doi: 10.1074/jbc.M306413200.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 45680-45689
-
-
Nishi, J.1
Sheikh, J.2
Mizuguchi, K.3
Luisi, B.4
Burland, V.5
Boutin, A.6
-
84
-
-
33645062695
-
Virulence and drug resistance roles of multidrug efflux systems of Salmonella enterica serovar Typhimurium
-
Nishino, K., Latifi, T., and Groisman, E. (2006). Virulence and drug resistance roles of multidrug efflux systems of Salmonella enterica serovar Typhimurium. Mol. Microbiol. 59, 126-141. doi: 10.1111/j.1365-2958.2005.04940.x.
-
(2006)
Mol. Microbiol
, vol.59
, pp. 126-141
-
-
Nishino, K.1
Latifi, T.2
Groisman, E.3
-
85
-
-
84902268313
-
Type II secretion system: a magic beanstalk or a protein escalator
-
Nivaskumar, M., and Francetic, O. (2014). Type II secretion system: a magic beanstalk or a protein escalator. Biochim. Biophys. Acta-Mol. Cell Res. 1843, 1568-1577. doi: 10.1016/j.bbamcr.2013.12.020.
-
(2014)
Biochim. Biophys. Acta-Mol. Cell Res
, vol.1843
, pp. 1568-1577
-
-
Nivaskumar, M.1
Francetic, O.2
-
86
-
-
0031278034
-
A family of Gram-negative bacterial outer membrane factors that function in the export of proteins, carbohydrates, drugs and heavy metals from Gram-negative bacteria
-
Paulsen, I., Park, J., Choi, P., and Saier, M. (1997). A family of Gram-negative bacterial outer membrane factors that function in the export of proteins, carbohydrates, drugs and heavy metals from Gram-negative bacteria. FEMS Microbiol. Lett. 156, 1-8. doi: 10.1016/S0378-1097(97)00379-0.
-
(1997)
FEMS Microbiol. Lett
, vol.156
, pp. 1-8
-
-
Paulsen, I.1
Park, J.2
Choi, P.3
Saier, M.4
-
87
-
-
79952132531
-
Structures of seffluential open states in a symmetrical opening transition of the TolC exit duct
-
Pei, X., Hinchliffe, P., Symmons, M. F., Koronakis, E., Benz, R., Hughes, C., et al. (2011). Structures of seffluential open states in a symmetrical opening transition of the TolC exit duct. Proc. Natl. Acad. Sci. U.S.A. 108, 2112-2117. doi: 10.1073/pnas.1012588108.
-
(2011)
Proc. Natl. Acad. Sci. U.S.A
, vol.108
, pp. 2112-2117
-
-
Pei, X.1
Hinchliffe, P.2
Symmons, M.F.3
Koronakis, E.4
Benz, R.5
Hughes, C.6
-
88
-
-
77951650335
-
Structural and dynamical insights into the opening mechanism of P. aeruginosa OprM channel
-
Phan, G., Benabdelhak, H., Lascombe, M., Benas, P., Rety, S., Picard, M., et al. (2010). Structural and dynamical insights into the opening mechanism of P. aeruginosa OprM channel. Structure 18, 507-517. doi: 10.1016/j.str.2010.01.018.
-
(2010)
Structure
, vol.18
, pp. 507-517
-
-
Phan, G.1
Benabdelhak, H.2
Lascombe, M.3
Benas, P.4
Rety, S.5
Picard, M.6
-
89
-
-
33747154459
-
Multidrug-resistance efflux pumps-not just for resistance
-
Piddock, L. J. V. (2006). Multidrug-resistance efflux pumps-not just for resistance. Nat. Rev. Microbiol. 4, 629-636. doi: 10.1038/nrmicro1464.
-
(2006)
Nat. Rev. Microbiol
, vol.4
, pp. 629-636
-
-
Piddock, L.J.V.1
-
90
-
-
84857195282
-
The crisis of no new antibiotics-what is the way forward?
-
Piddock, L. J. V. (2012). The crisis of no new antibiotics-what is the way forward? Lancet Infect. Dis. 12, 249-253. doi: 10.1016/S1473-3099(11)70316-4.
-
(2012)
Lancet Infect. Dis
, vol.12
, pp. 249-253
-
-
Piddock, L.J.V.1
-
91
-
-
84908539534
-
Understanding the basis of antibiotic resistance: a platform for drug discovery
-
Piddock, L. J. V. (2014). Understanding the basis of antibiotic resistance: a platform for drug discovery. Microbiology 160, 2366-2373. doi: 10.1099/mic.0.082412-0.
-
(2014)
Microbiology
, vol.160
, pp. 2366-2373
-
-
Piddock, L.J.V.1
-
92
-
-
27144531235
-
Mutations in HlyD, part of the type 1 translocator for hemolysin secretion, affect the folding of the secreted toxin
-
Pimenta, A., Racher, K., Jamieson, L., Blight, M., and Holland, I. (2005). Mutations in HlyD, part of the type 1 translocator for hemolysin secretion, affect the folding of the secreted toxin. J. Bacteriol. 187, 7471-7480. doi: 10.1128/JB.187.21.7471-7480.2005.
-
(2005)
J. Bacteriol
, vol.187
, pp. 7471-7480
-
-
Pimenta, A.1
Racher, K.2
Jamieson, L.3
Blight, M.4
Holland, I.5
-
93
-
-
64649100965
-
Drug transport mechanism of the AcrB efflux pump
-
Pos, K. M. (2009). Drug transport mechanism of the AcrB efflux pump. Biochim. Biophys. Acta 1794, 782-793. doi: 10.1016/j.bbapap.2008.12.015.
-
(2009)
Biochim. Biophys. Acta
, vol.1794
, pp. 782-793
-
-
Pos, K.M.1
-
94
-
-
84888251078
-
RND efflux pumps: structural information translated into function and inhibition mechanisms
-
Ruggerone, P., Murakami, S., Pos, K. M., Vargiu, A. V. (2013) RND efflux pumps: structural information translated into function and inhibition mechanisms. Curr. Top. Med. Chem. 13, 3079-3100. doi: 10.2174/15680266113136660220.
-
(2013)
Curr. Top. Med. Chem
, vol.13
, pp. 3079-3100
-
-
Ruggerone, P.1
Murakami, S.2
Pos, K.M.3
Vargiu, A.V.4
-
95
-
-
19444364649
-
Structure of the ATPase subunit CysA of the putative sulfate ATP-binding cassette (ABC) transporter from Alicyclobacillus acidocaldarius
-
Scheffel, F., Demmer, U., Warkentin, E., Hülsmann, A., Schneider, E., and Ermler, U. (2005). Structure of the ATPase subunit CysA of the putative sulfate ATP-binding cassette (ABC) transporter from Alicyclobacillus acidocaldarius. FEBS Lett. 579, 2953-2958. doi: 10.1016/j.febslet.2005.04.017.
-
(2005)
FEBS Lett
, vol.579
, pp. 2953-2958
-
-
Scheffel, F.1
Demmer, U.2
Warkentin, E.3
Hülsmann, A.4
Schneider, E.5
Ermler, U.6
-
96
-
-
67649402299
-
Transitions between closed and open conformations of TolC: the effects of ions in simulations
-
Schulz, R., and Kleinekathöfer, U. (2009). Transitions between closed and open conformations of TolC: the effects of ions in simulations. Biophys. J. 96, 3116-3125. doi: 10.1016/j.bpj.2009.01.021.
-
(2009)
Biophys. J
, vol.96
, pp. 3116-3125
-
-
Schulz, R.1
Kleinekathöfer, U.2
-
97
-
-
78751477224
-
Challenges of antibacterial discovery
-
Silver, L. L. (2011). Challenges of antibacterial discovery. Clin. Microbiol. Rev. 24, 71-109. doi: 10.1128/CMR.00030-10.
-
(2011)
Clin. Microbiol. Rev
, vol.24
, pp. 71-109
-
-
Silver, L.L.1
-
98
-
-
61749095310
-
NMR structure determination of a segmentally labeled glycoprotein using in vitro glycosylation
-
Slynko, V., Schubert, M., Numao, S., Kowarik, M., Aebi, M., and Allain, F. H. (2009). NMR structure determination of a segmentally labeled glycoprotein using in vitro glycosylation. J. Am. Chem. Soc. 131, 1274-1281. doi: 10.1021/ja808682v.
-
(2009)
J. Am. Chem. Soc
, vol.131
, pp. 1274-1281
-
-
Slynko, V.1
Schubert, M.2
Numao, S.3
Kowarik, M.4
Aebi, M.5
Allain, F.H.6
-
99
-
-
84903512517
-
Interaction mediated by the putative tip regions of MdsA and MdsC in the formation of a Salmonella-specific tripartite efflux pump
-
Song, S., Hwang, S., Lee, S., Ha, N., and Lee, K. (2014). Interaction mediated by the putative tip regions of MdsA and MdsC in the formation of a Salmonella-specific tripartite efflux pump. PLoS ONE 9:e100881. doi: 10.1371/journal.pone.0100881.
-
(2014)
PLoS ONE
, vol.9
-
-
Song, S.1
Hwang, S.2
Lee, S.3
Ha, N.4
Lee, K.5
-
100
-
-
77149159117
-
Peptidomimetic antibiotics target outer-membrane biogenesis in Pseudomonas aeruginosa
-
Srinivas, N., Jetter, P., Ueberbacher, B. J., Werneburg, M., Zerbe, K., Steinmann, J., et al. (2010). Peptidomimetic antibiotics target outer-membrane biogenesis in Pseudomonas aeruginosa. Science 327, 1010-1013. doi: 10.1126/science.1182749.
-
(2010)
Science
, vol.327
, pp. 1010-1013
-
-
Srinivas, N.1
Jetter, P.2
Ueberbacher, B.J.3
Werneburg, M.4
Zerbe, K.5
Steinmann, J.6
-
101
-
-
84892809413
-
Structure-function analysis of the ATP-driven glycolipid efflux pump DevBCA reveals complex organization with TolC/HgdD
-
Staron, P., Forchhammer, K., and Maldener, I. (2014). Structure-function analysis of the ATP-driven glycolipid efflux pump DevBCA reveals complex organization with TolC/HgdD. FEBS Lett. 588, 395-400. doi: 10.1016/j.febslet.2013.12.004.
-
(2014)
FEBS Lett
, vol.588
, pp. 395-400
-
-
Staron, P.1
Forchhammer, K.2
Maldener, I.3
-
102
-
-
33748638824
-
Importance of the adaptor (membrane fusion) protein hairpin domain for the functionality of multidrug efflux pumps
-
Stegmeier, J. F., Polleichtner, G., Brandes, N., Hotz, C., and Andersen, C. (2006). Importance of the adaptor (membrane fusion) protein hairpin domain for the functionality of multidrug efflux pumps. Biochemistry 45, 10303-10312. doi: 10.1021/bi060320g.
-
(2006)
Biochemistry
, vol.45
, pp. 10303-10312
-
-
Stegmeier, J.F.1
Polleichtner, G.2
Brandes, N.3
Hotz, C.4
Andersen, C.5
-
103
-
-
84865088476
-
Charged amino acids (R83, E567, D617, E625, R669, and K678) of CusA are required for metal ion transport in the Cus efflux system
-
Su, C., Long, F., Lei, H., Bolla, J. R., Do, S. V., Rajashankar, K. R., et al. (2012). Charged amino acids (R83, E567, D617, E625, R669, and K678) of CusA are required for metal ion transport in the Cus efflux system. J. Mol. Biol. 422, 429-441. doi: 10.1016/j.jmb.2012.05.038.
-
(2012)
J. Mol. Biol
, vol.422
, pp. 429-441
-
-
Su, C.1
Long, F.2
Lei, H.3
Bolla, J.R.4
Do, S.V.5
Rajashankar, K.R.6
-
104
-
-
79952145187
-
Crystal structure of the CusBA heavy-metal efflux complex of Escherichia coli
-
Su, C., Long, F., Zimmermann, M. T., Rajashankar, K. R., Jernigan, R. L., and Yu, E. W. (2011). Crystal structure of the CusBA heavy-metal efflux complex of Escherichia coli. Nature 470, 558-562. doi: 10.1038/nature09743.
-
(2011)
Nature
, vol.470
, pp. 558-562
-
-
Su, C.1
Long, F.2
Zimmermann, M.T.3
Rajashankar, K.R.4
Jernigan, R.L.5
Yu, E.W.6
-
105
-
-
84904165566
-
Crystal structure of the Campylobacter jejuni CmeC outer membrane channel
-
Su, C., Radhakrishnan, A., Kumar, N., Long, F., Bolla, J. R., Lei, H., et al. (2014). Crystal structure of the Campylobacter jejuni CmeC outer membrane channel. Protein Sci. 23, 954-961. doi: 10.1002/pro.2478.
-
(2014)
Protein Sci
, vol.23
, pp. 954-961
-
-
Su, C.1
Radhakrishnan, A.2
Kumar, N.3
Long, F.4
Bolla, J.R.5
Lei, H.6
-
106
-
-
70349558132
-
Crystal structure of the membrane fusion protein CusB from Escherichia coli
-
Su, C., Yang, F., Long, F., Reyon, D., Routh, M. D., Kuo, D. W., et al. (2009). Crystal structure of the membrane fusion protein CusB from Escherichia coli. J. Mol. Biol. 393, 342-355. doi: 10.1016/j.jmb.2009.08.029.
-
(2009)
J. Mol. Biol
, vol.393
, pp. 342-355
-
-
Su, C.1
Yang, F.2
Long, F.3
Reyon, D.4
Routh, M.D.5
Kuo, D.W.6
-
107
-
-
66349137043
-
The assembled structure of a complete tripartite bacterial multidrug efflux pump
-
Symmons, M. F., Bokma, E., Koronakis, E., Hughes, C., and Koronakis, V. (2009). The assembled structure of a complete tripartite bacterial multidrug efflux pump. Proc. Natl. Acad. Sci. U.S.A. 106, 7173-7178. doi: 10.1073/pnas.0900693106.
-
(2009)
Proc. Natl. Acad. Sci. U.S.A
, vol.106
, pp. 7173-7178
-
-
Symmons, M.F.1
Bokma, E.2
Koronakis, E.3
Hughes, C.4
Koronakis, V.5
-
108
-
-
23944509010
-
Direct interaction of multidrug efflux transporter AcrB and outer membrane channel TolC detected via site-directed disulfide cross-linking
-
Tamura, N., Murakami, S., Oyama, Y., Ishiguro, M., and Yamaguchi, A. (2005). Direct interaction of multidrug efflux transporter AcrB and outer membrane channel TolC detected via site-directed disulfide cross-linking. Biochemistry 44, 11115-11121. doi: 10.1021/bi050452u.
-
(2005)
Biochemistry
, vol.44
, pp. 11115-11121
-
-
Tamura, N.1
Murakami, S.2
Oyama, Y.3
Ishiguro, M.4
Yamaguchi, A.5
-
109
-
-
84876043827
-
Insight into the assembly mechanism in the supramolecular rings of the sodium-driven Vibrio flagellar motor from the structure of FlgT
-
Terashima, H., Li, N., Sakuma, M., Koike, M., Kojima, S., Homma, M., et al. (2013). Insight into the assembly mechanism in the supramolecular rings of the sodium-driven Vibrio flagellar motor from the structure of FlgT. Proc. Natl. Acad. Sci. U.S.A. 110, 6133-6138. doi: 10.1073/pnas.1222655110.
-
(2013)
Proc. Natl. Acad. Sci. U.S.A
, vol.110
, pp. 6133-6138
-
-
Terashima, H.1
Li, N.2
Sakuma, M.3
Koike, M.4
Kojima, S.5
Homma, M.6
-
110
-
-
0032538793
-
Substrate-induced assembly of a contiguous channel for protein export from E. coli: reversible bridging of an inner-membrane translocase to an outer membrane exit pore
-
Thanabalu, T., Koronakis, E., Hughes, C., and Koronakis, V. (1998). Substrate-induced assembly of a contiguous channel for protein export from E. coli: reversible bridging of an inner-membrane translocase to an outer membrane exit pore. EMBO J. 17, 6487-6496. doi: 10.1093/emboj/17.22.6487.
-
(1998)
EMBO J
, vol.17
, pp. 6487-6496
-
-
Thanabalu, T.1
Koronakis, E.2
Hughes, C.3
Koronakis, V.4
-
111
-
-
84902329691
-
The type 1 secretion pathway-the hemolysin system and beyond
-
Thomas, S., Holland, I. B., and Schmitt, L. (2014). The type 1 secretion pathway-the hemolysin system and beyond. Biochim. Biophys. Acta. 1843, 1629-1641. doi: 10.1016/j.bbamcr.2013.09.017.
-
(2014)
Biochim. Biophys. Acta
, vol.1843
, pp. 1629-1641
-
-
Thomas, S.1
Holland, I.B.2
Schmitt, L.3
-
112
-
-
33846263341
-
Reconstitution of the Escherichia coli macrolide transporter: the periplasmic membrane fusion protein MacA stimulates the ATPase activity of MacB
-
Tikhonova, E. B., Devroy, V. K., Lau, S. Y., and Zgurskaya, H. I. (2007). Reconstitution of the Escherichia coli macrolide transporter: the periplasmic membrane fusion protein MacA stimulates the ATPase activity of MacB. Mol. Microbiol. 63, 895-910. doi: 10.1111/j.1365-2958.2006.05549.x.
-
(2007)
Mol. Microbiol
, vol.63
, pp. 895-910
-
-
Tikhonova, E.B.1
Devroy, V.K.2
Lau, S.Y.3
Zgurskaya, H.I.4
-
113
-
-
0036889445
-
Chimeric analysis of the multicomponent multidrug efflux transporters from Gram-negative bacteria
-
Tikhonova, E., Wang, Q., and Zgurskaya, H. (2002). Chimeric analysis of the multicomponent multidrug efflux transporters from Gram-negative bacteria. J. Bacteriol. 184, 6499-6507. doi: 10.1128/JB.184.23.6499-6507.2002.
-
(2002)
J. Bacteriol
, vol.184
, pp. 6499-6507
-
-
Tikhonova, E.1
Wang, Q.2
Zgurskaya, H.3
-
114
-
-
79955388745
-
Seffluential mechanism of assembly of multidrug efflux pump AcrAB-TolC
-
Tikhonova, E. B., Yamada, Y., and Zgurskaya, H. I. (2011). Seffluential mechanism of assembly of multidrug efflux pump AcrAB-TolC. Chem. Biol. 18, 454-463. doi: 10.1016/j.chembiol.2011.02.011.
-
(2011)
Chem. Biol
, vol.18
, pp. 454-463
-
-
Tikhonova, E.B.1
Yamada, Y.2
Zgurskaya, H.I.3
-
115
-
-
36749071555
-
Crystal structure of AcrB in complex with a single transmembrane subunit reveals another twist
-
Törnroth-Horsefield, S., Gourdon, P., Horsefield, R., Brive, L., Yamamoto, N., Mori, H., et al. (2007). Crystal structure of AcrB in complex with a single transmembrane subunit reveals another twist. Structure 15, 1663-1673. doi: 10.1016/j.str.2007.09.023.
-
(2007)
Structure
, vol.15
, pp. 1663-1673
-
-
Törnroth-Horsefield, S.1
Gourdon, P.2
Horsefield, R.3
Brive, L.4
Yamamoto, N.5
Mori, H.6
-
116
-
-
3242890387
-
Interactions underlying assembly of the Escherichia coli AcrAB-TolC multidrug efflux system
-
Touzé, T., Eswaran, J., Bokma, E., Koronakis, E., Hughes, C., and Koronakis, V. (2004). Interactions underlying assembly of the Escherichia coli AcrAB-TolC multidrug efflux system. Mol. Microbiol. 53, 697-706. doi: 10.1111/j.1365-2958.2004.04158.x.
-
(2004)
Mol. Microbiol
, vol.53
, pp. 697-706
-
-
Touzé, T.1
Eswaran, J.2
Bokma, E.3
Koronakis, E.4
Hughes, C.5
Koronakis, V.6
-
117
-
-
77955658266
-
Structure of reconstituted bacterial membrane efflux pump by cryo-electron tomography
-
Trépout, S., Taveau, J., Benabdelhak, H., Granier, T., Ducruix, A., Frangakis, A. S., et al. (2010). Structure of reconstituted bacterial membrane efflux pump by cryo-electron tomography. Biochim. Biophys. Acta. 1798, 1953-1960. doi: 10.1016/j.bbamem.2010.06.019.
-
(2010)
Biochim. Biophys. Acta
, vol.1798
, pp. 1953-1960
-
-
Trépout, S.1
Taveau, J.2
Benabdelhak, H.3
Granier, T.4
Ducruix, A.5
Frangakis, A.S.6
-
118
-
-
79958281760
-
Structure and function of a membrane component SecDF that enhances protein export
-
Tsukazaki, T., Mori, H., Echizen, Y., Ishitani, R., Fukai, S., Tanaka, T., et al. (2011). Structure and function of a membrane component SecDF that enhances protein export. Nature 474, 235-238. doi: 10.1038/nature09980.
-
(2011)
Nature
, vol.474
, pp. 235-238
-
-
Tsukazaki, T.1
Mori, H.2
Echizen, Y.3
Ishitani, R.4
Fukai, S.5
Tanaka, T.6
-
119
-
-
84884999466
-
Structure and dynamics of the N-terminal domain of the Cu(I) binding protein CusB
-
Ucisik, M. N., Chakravorty, D. K., and Merz, K. M. Jr. (2013). Structure and dynamics of the N-terminal domain of the Cu(I) binding protein CusB. Biochemistry 52, 6911-6923. doi: 10.1021/bi400606b.
-
(2013)
Biochemistry
, vol.52
, pp. 6911-6923
-
-
Ucisik, M.N.1
Chakravorty, D.K.2
Merz, K.M.3
-
120
-
-
33745686037
-
Flexibility in a drug transport accessory protein: molecular dynamics simulations of MexA
-
Vaccaro, L., Koronakis, V., and Sansom, M. (2006). Flexibility in a drug transport accessory protein: molecular dynamics simulations of MexA. Biophys. J. 91, 558-564. doi: 10.1529/biophysj105.080010.
-
(2006)
Biophys. J
, vol.91
, pp. 558-564
-
-
Vaccaro, L.1
Koronakis, V.2
Sansom, M.3
-
121
-
-
84902256586
-
Type V secretion: from biogenesis to biotechnology
-
van Ulsen, P., Rahman, S. U., Jong, W. S. P., Daleke-Schermerhom, M. H., and Luirink, J. (2014). Type V secretion: from biogenesis to biotechnology. Biochim. Biophys. Acta. 1843, 1592-1611. doi: 10.1016/j.bbamcr.2013.11.006.
-
(2014)
Biochim. Biophys. Acta
, vol.1843
, pp. 1592-1611
-
-
van Ulsen, P.1
Rahman, S.U.2
Jong, W.S.P.3
Daleke-Schermerhom, M.H.4
Luirink, J.5
-
122
-
-
84860181497
-
MmpL genes are associated with mycolic acid metabolism in Mycobacteria and Corynebacteria
-
Varela, C., Rittmann, D., Singh, A., Krumbach, K., Bhatt, K., Eggeling, L., et al. (2012). MmpL genes are associated with mycolic acid metabolism in Mycobacteria and Corynebacteria. Chem. Biol. 19, 498-506. doi: 10.1016/j.chembiol.2012.03.006.
-
(2012)
Chem. Biol
, vol.19
, pp. 498-506
-
-
Varela, C.1
Rittmann, D.2
Singh, A.3
Krumbach, K.4
Bhatt, K.5
Eggeling, L.6
-
123
-
-
33744748622
-
Isolation and characterization of VceC gain-of-function mutants that can function with the AcrAB multiple-drug-resistant efflux pump of Escherichia coli
-
Vediyappan, G., Borisova, T., and Fralick, J. (2006). Isolation and characterization of VceC gain-of-function mutants that can function with the AcrAB multiple-drug-resistant efflux pump of Escherichia coli. J. Bacteriol. 188, 3757-3762. doi: 10.1128/JB.00038-06.
-
(2006)
J. Bacteriol
, vol.188
, pp. 3757-3762
-
-
Vediyappan, G.1
Borisova, T.2
Fralick, J.3
-
124
-
-
84859783528
-
Photo-induced proton gradients for the in vitro investigation of bacterial efflux pumps
-
Verchère, A., Broutin, I., and Picard, M. (2012). Photo-induced proton gradients for the in vitro investigation of bacterial efflux pumps. Sci. Rep. 2:306. doi: 10.1038/srep00306.
-
(2012)
Sci. Rep
, vol.2
, pp. 306
-
-
Verchère, A.1
Broutin, I.2
Picard, M.3
-
125
-
-
84863391966
-
Interdomain flexibility and pH-induced conformational changes of AcrA revealed by molecular dynamics simulations
-
Wang, B., Weng, J., Fan, K., and Wang, W. (2012). Interdomain flexibility and pH-induced conformational changes of AcrA revealed by molecular dynamics simulations. J. Phys. Chem. B 116, 3411-3420. doi: 10.1021/jp212221v.
-
(2012)
J. Phys. Chem. B
, vol.116
, pp. 3411-3420
-
-
Wang, B.1
Weng, J.2
Fan, K.3
Wang, W.4
-
126
-
-
84896695577
-
Genetic assessment of the role of AcrB beta hairpins in the assembly of the TolC-AcrAB multidrug efflux pump of Escherichia coli
-
Weeks, J. W., Bavro, V. N., and Misra, R. (2014). Genetic assessment of the role of AcrB beta hairpins in the assembly of the TolC-AcrAB multidrug efflux pump of Escherichia coli. Mol. Microbiol. 91, 965-975. doi: 10.1111/mmi.12508.
-
(2014)
Mol. Microbiol
, vol.91
, pp. 965-975
-
-
Weeks, J.W.1
Bavro, V.N.2
Misra, R.3
-
127
-
-
77949360141
-
AcrA suppressor alterations reverse the drug hypersensitivity phenotype of a TolC mutant by inducing TolC aperture opening
-
Weeks, J. W., Celaya-Kolb, T., Pecora, S., and Misra, R. (2010). AcrA suppressor alterations reverse the drug hypersensitivity phenotype of a TolC mutant by inducing TolC aperture opening. Mol. Microbiol. 75, 1468-1483. doi: 10.1111/j.1365-2958.2010.07068.x.
-
(2010)
Mol. Microbiol
, vol.75
, pp. 1468-1483
-
-
Weeks, J.W.1
Celaya-Kolb, T.2
Pecora, S.3
Misra, R.4
-
128
-
-
0014988278
-
The tolC locus in Escherichia coli K12
-
Whitney, E. N. (1971). The tolC locus in Escherichia coli K12. Genetics 67, 39-53.
-
(1971)
Genetics
, vol.67
, pp. 39-53
-
-
Whitney, E.N.1
-
129
-
-
84890859575
-
Towards understanding promiscuity in multidrug efflux pumps
-
Wong, K., Ma, J., Rothnie, A., Biggin, P. C., and Kerr, I. D. (2014). Towards understanding promiscuity in multidrug efflux pumps. Trends Biochem. Sci. 39, 8-16. doi: 10.1016/j.tibs.2013.11.002.
-
(2014)
Trends Biochem. Sci
, vol.39
, pp. 8-16
-
-
Wong, K.1
Ma, J.2
Rothnie, A.3
Biggin, P.C.4
Kerr, I.D.5
-
130
-
-
79955946992
-
Funnel-like hexameric assembly of the periplasmic adapter protein in the tripartite multidrug efflux pump in Gram-negative bacteria
-
Xu, Y., Lee, M., Moeller, A., Song, S., Yoon, B., Kim, H., et al. (2011a). Funnel-like hexameric assembly of the periplasmic adapter protein in the tripartite multidrug efflux pump in Gram-negative bacteria. J. Biol. Chem. 286, 17910-17920. doi: 10.1074/jbc.M111.238535.
-
(2011)
J. Biol. Chem
, vol.286
, pp. 17910-17920
-
-
Xu, Y.1
Lee, M.2
Moeller, A.3
Song, S.4
Yoon, B.5
Kim, H.6
-
131
-
-
79953878893
-
Functional implications of an intermeshing cogwheel-like interaction between TolC and MacA in the action of macrolide-specific efflux pump MacAB-TolC
-
Xu, Y., Song, S., Moeller, A., Kim, N., Piao, S., Sim, S., et al. (2011b). Functional implications of an intermeshing cogwheel-like interaction between TolC and MacA in the action of macrolide-specific efflux pump MacAB-TolC. J. Biol. Chem. 286, 13541-13549. doi: 10.1074/jbc.M110.202598.
-
(2011)
J. Biol. Chem
, vol.286
, pp. 13541-13549
-
-
Xu, Y.1
Song, S.2
Moeller, A.3
Kim, N.4
Piao, S.5
Sim, S.6
-
132
-
-
84859513090
-
Assembly and channel opening of outer membrane protein in tripartite drug efflux pumps of Gram-negative bacteria
-
Xu, Y., Moeller, A., Jun, S., Le, M., Yoon, B., Kim, J., et al. (2012). Assembly and channel opening of outer membrane protein in tripartite drug efflux pumps of Gram-negative bacteria. J. Biol. Chem. 287, 11740-11750. doi: 10.1074/jbc.M111.329375.
-
(2012)
J. Biol. Chem
, vol.287
, pp. 11740-11750
-
-
Xu, Y.1
Moeller, A.2
Jun, S.3
Le, M.4
Yoon, B.5
Kim, J.6
-
133
-
-
77950858238
-
The tip region of the MacA alpha-hairpin is important for the binding to TolC to the Escherichia coli MacAB-TolC pump
-
Xu, Y., Sim, S., Song, S., Piao, S., Kim, H., Jin, X. L., et al. (2010). The tip region of the MacA alpha-hairpin is important for the binding to TolC to the Escherichia coli MacAB-TolC pump. Biochem. Biophys. Res. Commun. 394, 962-965. doi: 10.1016/j.bbrc.2010.03.097.
-
(2010)
Biochem. Biophys. Res. Commun
, vol.394
, pp. 962-965
-
-
Xu, Y.1
Sim, S.2
Song, S.3
Piao, S.4
Kim, H.5
Jin, X.L.6
-
134
-
-
38349014092
-
Cu(I) recognition via cation-pi and methionine interactions in CusF
-
Xue, Y., Davis, A. V., Balakrishnan, G., Stasser, J. P., Staehlin, B. M., Focia, P., et al. (2008). Cu(I) recognition via cation-pi and methionine interactions in CusF. Nat. Chem. Biol. 4, 107-109. doi: 10.1038/nchembio.2007.57.
-
(2008)
Nat. Chem. Biol
, vol.4
, pp. 107-109
-
-
Xue, Y.1
Davis, A.V.2
Balakrishnan, G.3
Stasser, J.P.4
Staehlin, B.M.5
Focia, P.6
-
135
-
-
84866307460
-
YknWXYZ is an unusual four-component transporter with a role in protection against sporulation-delaying-protein-induced killing of Bacillus subtilis
-
Yamada, Y., Tikhonova, E. B., and Zgurskaya, H. I. (2012). YknWXYZ is an unusual four-component transporter with a role in protection against sporulation-delaying-protein-induced killing of Bacillus subtilis. J. Bacteriol. 194, 4386-4394. doi: 10.1128/JB.00223-12.
-
(2012)
J. Bacteriol
, vol.194
, pp. 4386-4394
-
-
Yamada, Y.1
Tikhonova, E.B.2
Zgurskaya, H.I.3
-
136
-
-
0035174213
-
Carboxy-terminal region involved in activity of Escherichia coli TolC
-
Yamanaka, H., Izawa, H., and Okamoto, K. (2001). Carboxy-terminal region involved in activity of Escherichia coli TolC. J. Bacteriol. 183, 6961-6964. doi: 10.1128/JB.183.23.6961-6964.2001.
-
(2001)
J. Bacteriol
, vol.183
, pp. 6961-6964
-
-
Yamanaka, H.1
Izawa, H.2
Okamoto, K.3
-
137
-
-
0036385660
-
Site-directed mutagenesis studies of the amino acid residue at position 412 of Escherichia coli TolC which is required for the activity
-
Yamanaka, H., Nomura, T., Morisada, N., Shinoda, S., and Okamoto, K. (2002). Site-directed mutagenesis studies of the amino acid residue at position 412 of Escherichia coli TolC which is required for the activity. Microb. Pathog. 33, 81-89. doi: 10.1006/mpat.2002.0519.
-
(2002)
Microb. Pathog
, vol.33
, pp. 81-89
-
-
Yamanaka, H.1
Nomura, T.2
Morisada, N.3
Shinoda, S.4
Okamoto, K.5
-
138
-
-
84925156346
-
The I-TASSER suite: protein structure and function prediction
-
Yang, J., Yan, R., Roy, A., Xu, D., Poisson, J., and Zhang, Y. (2015). The I-TASSER suite: protein structure and function prediction. Nat. Methods 12, 7-8. doi: 10.1038/nmeth.3213.
-
(2015)
Nat. Methods
, vol.12
, pp. 7-8
-
-
Yang, J.1
Yan, R.2
Roy, A.3
Xu, D.4
Poisson, J.5
Zhang, Y.6
-
139
-
-
21544470513
-
Structure of the uncleaved ectodomain of the paramyxovirus (hPIV3) fusion protein
-
Yin, H., Paterson, R., Wen, X., Lamb, R., and Jardetzky, T. (2005). Structure of the uncleaved ectodomain of the paramyxovirus (hPIV3) fusion protein. Proc. Natl. Acad. Sci. U.S.A. 102, 9288-9293. doi: 10.1073/pnas.0503989102.
-
(2005)
Proc. Natl. Acad. Sci. U.S.A
, vol.102
, pp. 9288-9293
-
-
Yin, H.1
Paterson, R.2
Wen, X.3
Lamb, R.4
Jardetzky, T.5
-
140
-
-
0042238051
-
Complete atomic model of the bacterial flagellar filament by electron cryomicroscopy
-
Yonekura, K., Maki-Yonekura, S., and Namba, K. (2003). Complete atomic model of the bacterial flagellar filament by electron cryomicroscopy. Nature 424, 643-650. doi: 10.1038/nature01830.
-
(2003)
Nature
, vol.424
, pp. 643-650
-
-
Yonekura, K.1
Maki-Yonekura, S.2
Namba, K.3
-
141
-
-
0033797251
-
An operon for a putative ATP-binding cassette transport system involved in acetoin utilization of Bacillus subtilis
-
Yoshida, K., Fujita, Y., and Ehrlich, S. (2000). An operon for a putative ATP-binding cassette transport system involved in acetoin utilization of Bacillus subtilis. J. Bacteriol. 182, 5454-5461. doi: 10.1128/JB.182.19.5454-5461.2000.
-
(2000)
J. Bacteriol
, vol.182
, pp. 5454-5461
-
-
Yoshida, K.1
Fujita, Y.2
Ehrlich, S.3
-
142
-
-
70349245247
-
Functional interaction sites of OprM with MexAB in the Pseudomonas aeruginosa multidrug efflux pump
-
Yoshihara, E., Eda, S., and Kaitou, S. (2009). Functional interaction sites of OprM with MexAB in the Pseudomonas aeruginosa multidrug efflux pump. FEMS Microbiol. Lett. 299, 200-204. doi: 10.1111/j.1574-6968.2009.01752.x.
-
(2009)
FEMS Microbiol. Lett
, vol.299
, pp. 200-204
-
-
Yoshihara, E.1
Eda, S.2
Kaitou, S.3
-
143
-
-
63449091256
-
Crystal structure of the periplasmic component of a tripartite macrolide-specific efflux pump
-
Yum, S., Xu, Y., Piao, S., Sim, S., Kim, H., Jo, W., et al. (2009). Crystal structure of the periplasmic component of a tripartite macrolide-specific efflux pump. J. Mol. Biol. 387, 1286-1297. doi: 10.1016/j.jmb.2009.02.048.
-
(2009)
J. Mol. Biol
, vol.387
, pp. 1286-1297
-
-
Yum, S.1
Xu, Y.2
Piao, S.3
Sim, S.4
Kim, H.5
Jo, W.6
-
144
-
-
84857520919
-
Mechanism and function of the outer membrane channel TolC in multidrug resistance and physiology of enterobacteria
-
Zgurskaya, H. I., Krishnamoorthy, G., Ntreh, A., and Lu, S. (2011). Mechanism and function of the outer membrane channel TolC in multidrug resistance and physiology of enterobacteria. Front. Microbiol. 2:189. doi: 10.3389/fmicb.2011.00189.
-
(2011)
Front. Microbiol
, vol.2
, pp. 189
-
-
Zgurskaya, H.I.1
Krishnamoorthy, G.2
Ntreh, A.3
Lu, S.4
-
145
-
-
0033594886
-
Bypassing the periplasm: reconstitution of the AcrAB multidrug efflux pump of Escherichia coli
-
Zgurskaya, H., and Nikaido, H. (1999). Bypassing the periplasm: reconstitution of the AcrAB multidrug efflux pump of Escherichia coli. Proc. Natl. Acad. Sci. U.S.A. 96, 7190-7195. doi: 10.1073/pnas.96.13.7190.
-
(1999)
Proc. Natl. Acad. Sci. U.S.A
, vol.96
, pp. 7190-7195
-
-
Zgurskaya, H.1
Nikaido, H.2
-
146
-
-
0033940002
-
Cross-linked complex between oligomeric periplasmic lipoprotein AcrA and the inner-membrane-associated multidrug efflux pump AcrB from Escherichia coli
-
Zgurskaya, H., and Nikaido, H. (2000). Cross-linked complex between oligomeric periplasmic lipoprotein AcrA and the inner-membrane-associated multidrug efflux pump AcrB from Escherichia coli. J. Bacteriol. 182, 4264-4267. doi: 10.1128/JB.182.15.4264-4267.2000.
-
(2000)
J. Bacteriol
, vol.182
, pp. 4264-4267
-
-
Zgurskaya, H.1
Nikaido, H.2
-
147
-
-
84927520688
-
Mechanism of coupling drug transport reactions located in two different membranes
-
Zgurskaya, H. I., Weeks, J. W., Ntreh, A. T., Nickels, L. M., and Wolloscheck, D. (2015). Mechanism of coupling drug transport reactions located in two different membranes. Front. Microbiol. 6:100. doi: 10.3389/fmicb.2015.00100.
-
(2015)
Front. Microbiol
, vol.6
, pp. 100
-
-
Zgurskaya, H.I.1
Weeks, J.W.2
Ntreh, A.T.3
Nickels, L.M.4
Wolloscheck, D.5
-
148
-
-
64649087897
-
Structural and functional diversity of bacterial membrane fusion proteins
-
Zgurskaya, H. I., Yamada, Y., Tikhonova, E. B., Ge, Q., and Krishnamoorthy, G. (2009). Structural and functional diversity of bacterial membrane fusion proteins. Biochim. Biophys. Acta 1794, 794-807. doi: 10.1016/j.bbapap.2008.10.010.
-
(2009)
Biochim. Biophys. Acta
, vol.1794
, pp. 794-807
-
-
Zgurskaya, H.I.1
Yamada, Y.2
Tikhonova, E.B.3
Ge, Q.4
Krishnamoorthy, G.5
-
149
-
-
0033525105
-
Structural basis of multidrug recognition by BmrR, a transcription activator of a multidrug transporter
-
Zheleznova, E., Markham, P., Neyfakh, A., and Brennan, R. (1999). Structural basis of multidrug recognition by BmrR, a transcription activator of a multidrug transporter. Cell 96, 353-362. doi: 10.1016/S0092-8674(00)80548-6.
-
(1999)
Cell
, vol.96
, pp. 353-362
-
-
Zheleznova, E.1
Markham, P.2
Neyfakh, A.3
Brennan, R.4
-
150
-
-
84902267192
-
Architecture and assembly of the type VI secretion system
-
Zoued, A., Brunet, Y. R., Durand, E., Aschtgen, M., Logger, L., Douzi, B., et al. (2014) Architecture and assembly of the type VI secretion system. Biochim. Biophys. Acta. 1843, 1664-1673. doi: 10.1016/j.bbamcr.2014.03.018.
-
(2014)
Biochim. Biophys. Acta
, vol.1843
, pp. 1664-1673
-
-
Zoued, A.1
Brunet, Y.R.2
Durand, E.3
Aschtgen, M.4
Logger, L.5
Douzi, B.6
|