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Volumn 45, Issue 34, 2006, Pages 10303-10312

Importance of the adaptor (membrane fusion) protein hairpin domain for the functionality of multidrug efflux pumps

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; BIOLOGICAL MEMBRANES; CELLS; CROSSLINKING; ESCHERICHIA COLI;

EID: 33748638824     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi060320g     Document Type: Article
Times cited : (51)

References (45)
  • 1
    • 0038806687 scopus 로고    scopus 로고
    • The impact of antimicrobial resistance on health and economic outcomes
    • Cosgrove, S. E., and Carmeli, Y. (2003) The impact of antimicrobial resistance on health and economic outcomes, Clin. Infect. Dis. 36, 1433-1437.
    • (2003) Clin. Infect. Dis. , vol.36 , pp. 1433-1437
    • Cosgrove, S.E.1    Carmeli, Y.2
  • 2
    • 0033912430 scopus 로고    scopus 로고
    • Multidrug resistance mechanisms: Drug efflux across two membranes
    • Zgurskaya, H. I., and Nikaido, H. (2000) Multidrug resistance mechanisms: Drug efflux across two membranes, Mol. Microbiol. 37, 219-225.
    • (2000) Mol. Microbiol. , vol.37 , pp. 219-225
    • Zgurskaya, H.I.1    Nikaido, H.2
  • 3
    • 0034791408 scopus 로고    scopus 로고
    • Multidrug resistance in Gram-negative bacteria
    • Poole, K. (2001) Multidrug resistance in Gram-negative bacteria, Curr. Opin. Microbiol. 4, 500-508.
    • (2001) Curr. Opin. Microbiol. , vol.4 , pp. 500-508
    • Poole, K.1
  • 4
    • 0035425018 scopus 로고    scopus 로고
    • Protein export and drug efflux through bacterial channel-tunnels
    • Andersen, C., Hughes, C., and Koronakis, V. (2001) Protein export and drug efflux through bacterial channel-tunnels, Curr. Opin. Cell Biol. 13, 412-416.
    • (2001) Curr. Opin. Cell Biol. , vol.13 , pp. 412-416
    • Andersen, C.1    Hughes, C.2    Koronakis, V.3
  • 5
    • 0642345085 scopus 로고    scopus 로고
    • Channel-tunnels: Outer membrane components of type I secretion systems and multidrug efflux pumps of Gram-negative bacteria
    • Andersen, C. (2003) Channel-tunnels: Outer membrane components of type I secretion systems and multidrug efflux pumps of Gram-negative bacteria, Rev. Physiol. Biochem. Pharmacol. 147, 122-165.
    • (2003) Rev. Physiol. Biochem. Pharmacol. , vol.147 , pp. 122-165
    • Andersen, C.1
  • 6
    • 11144222920 scopus 로고    scopus 로고
    • Crystal structure of the drug discharge outer membrane protein, OprM, of Pseudomonas aeruginosa: Dual modes of membrane anchoring and occluded cavity end
    • Akama, H., Kanemaki, M., Yoshimura, M., Tsukihara, T., Kashiwagi, T., Yoneyama, H., Narita, S., Nakagawa, A., and Nakae, T. (2004) Crystal structure of the drug discharge outer membrane protein, OprM, of Pseudomonas aeruginosa: Dual modes of membrane anchoring and occluded cavity end, J. Biol. Chem. 279, 52816-52819.
    • (2004) J. Biol. Chem. , vol.279 , pp. 52816-52819
    • Akama, H.1    Kanemaki, M.2    Yoshimura, M.3    Tsukihara, T.4    Kashiwagi, T.5    Yoneyama, H.6    Narita, S.7    Nakagawa, A.8    Nakae, T.9
  • 7
    • 0034702177 scopus 로고    scopus 로고
    • Crystal structure of the bacterial membrane protein TolC central to multidrug efflux and protein export
    • Koronakis, V., Sharff, A., Koronakis, E., Luisi, B., and Hughes, C. (2000) Crystal structure of the bacterial membrane protein TolC central to multidrug efflux and protein export, Nature 405, 914-919.
    • (2000) Nature , vol.405 , pp. 914-919
    • Koronakis, V.1    Sharff, A.2    Koronakis, E.3    Luisi, B.4    Hughes, C.5
  • 8
    • 0037057652 scopus 로고    scopus 로고
    • Crystal structure of bacterial multidrug efflux transporter AcrB
    • Murakami, S., Nakashima, R., Yamashita, E., and Yamaguchi, A. (2002) Crystal structure of bacterial multidrug efflux transporter AcrB, Nature 419, 587-593.
    • (2002) Nature , vol.419 , pp. 587-593
    • Murakami, S.1    Nakashima, R.2    Yamashita, E.3    Yamaguchi, A.4
  • 9
    • 23944509010 scopus 로고    scopus 로고
    • Direct interaction of multidrug efflux transporter AcrB and outer membrane channel TolC detected via site-directed disulfide cross-linking
    • Tamura, N., Murakami, S., Oyama, Y., Ishiguro, M., and Yamaguchi, A. (2005) Direct interaction of multidrug efflux transporter AcrB and outer membrane channel TolC detected via site-directed disulfide cross-linking, Biochemistry 44, 11115-11121.
    • (2005) Biochemistry , vol.44 , pp. 11115-11121
    • Tamura, N.1    Murakami, S.2    Oyama, Y.3    Ishiguro, M.4    Yamaguchi, A.5
  • 10
    • 2942731519 scopus 로고    scopus 로고
    • Crystal structure of the membrane fusion protein, MexA, of the multidrug transporter in Pseudomonas aeruginosa
    • Akama, H., Matsuura, T., Kashiwagi, S., Yoneyama, H., Narita, S., Tsukihara, T., Nakagawa, A., and Nakae, T. (2004) Crystal structure of the membrane fusion protein, MexA, of the multidrug transporter in Pseudomonas aeruginosa, J. Biol. Chem. 279, 25939-25942.
    • (2004) J. Biol. Chem. , vol.279 , pp. 25939-25942
    • Akama, H.1    Matsuura, T.2    Kashiwagi, S.3    Yoneyama, H.4    Narita, S.5    Tsukihara, T.6    Nakagawa, A.7    Nakae, T.8
  • 12
    • 33644833626 scopus 로고    scopus 로고
    • Conformational flexibility in the multidrug efflux system protein AcrA
    • Mikolosko, J., Bobyk, K., Zgurskaya, H. I., and Ghosh, P. (2006) Conformational flexibility in the multidrug efflux system protein AcrA, Structure 14, 577-587.
    • (2006) Structure , vol.14 , pp. 577-587
    • Mikolosko, J.1    Bobyk, K.2    Zgurskaya, H.I.3    Ghosh, P.4
  • 13
    • 0033515434 scopus 로고    scopus 로고
    • Alignment and structure prediction of divergent protein families: Periplasmic and outer membrane proteins of bacterial efflux pumps
    • Johnson, J. M., and Church, G. M. (1999) Alignment and structure prediction of divergent protein families: Periplasmic and outer membrane proteins of bacterial efflux pumps, J. Mol. Biol. 287, 695-715.
    • (1999) J. Mol. Biol. , vol.287 , pp. 695-715
    • Johnson, J.M.1    Church, G.M.2
  • 15
    • 10044231647 scopus 로고    scopus 로고
    • Interaction between the TolC and AcrA proteins of a multidrug efflux system of Escherichia coli
    • Husain, F., Humbard, M., and Misra, R. (2004) Interaction between the TolC and AcrA proteins of a multidrug efflux system of Escherichia coli, J. Bacteriol. 186, 8533-8536.
    • (2004) J. Bacteriol. , vol.186 , pp. 8533-8536
    • Husain, F.1    Humbard, M.2    Misra, R.3
  • 16
    • 6044233423 scopus 로고    scopus 로고
    • Role of the membrane fusion protein in the assembly of resistance-nodulation-cell division multidrug efflux pump in Pseudomonas aeruginosa, Biochem
    • Mokhonov, V. V., Mokhonova, E. I., Akama, H., and Nakae, T. (2004) Role of the membrane fusion protein in the assembly of resistance-nodulation-cell division multidrug efflux pump in Pseudomonas aeruginosa, Biochem. Biophys. Res. Commun. 322, 483-489.
    • (2004) Biophys. Res. Commun. , vol.322 , pp. 483-489
    • Mokhonov, V.V.1    Mokhonova, E.I.2    Akama, H.3    Nakae, T.4
  • 17
    • 3542998054 scopus 로고    scopus 로고
    • AcrA, AcrB, and TolC of Escherichia coli form a stable intermembrane multidrug efflux complex
    • Tikhonova, E. B., and Zgurskaya, H. I. (2004) AcrA, AcrB, and TolC of Escherichia coli Form a Stable Intermembrane Multidrug Efflux Complex, J. Biol. Chem. 279, 32116-32124.
    • (2004) J. Biol. Chem. , vol.279 , pp. 32116-32124
    • Tikhonova, E.B.1    Zgurskaya, H.I.2
  • 18
    • 7644244749 scopus 로고    scopus 로고
    • Genetic evidence for functional interactions between TolC and AcrA proteins of a major antibiotic efflux pump of Escherichia coli
    • Gerken, H., and Misra, R. (2004) Genetic evidence for functional interactions between TolC and AcrA proteins of a major antibiotic efflux pump of Escherichia coli, Mol. Microbiol. 54, 620-631.
    • (2004) Mol. Microbiol. , vol.54 , pp. 620-631
    • Gerken, H.1    Misra, R.2
  • 19
    • 0035028431 scopus 로고    scopus 로고
    • Enhanced expression of the multidrug efflux pumps AcrAB and AcrEF associated with insertion element transposition in Escherichia coli mutants selected with a fluoroquinolone
    • Jellen-Ritter, A. S., and Kern, W. V. (2001) Enhanced expression of the multidrug efflux pumps AcrAB and AcrEF associated with insertion element transposition in Escherichia coli mutants selected with a fluoroquinolone, Antimicrob. Agents Chemother. 45, 1467-1472.
    • (2001) Antimicrob. Agents Chemother. , vol.45 , pp. 1467-1472
    • Jellen-Ritter, A.S.1    Kern, W.V.2
  • 20
    • 0034612342 scopus 로고    scopus 로고
    • One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products
    • Datsenko, K. A., and Wanner, B. L. (2000) One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products, Proc. Natl. Acad. Sci. U.S.A. 97, 6640-6645.
    • (2000) Proc. Natl. Acad. Sci. U.S.A. , vol.97 , pp. 6640-6645
    • Datsenko, K.A.1    Wanner, B.L.2
  • 22
    • 0024283925 scopus 로고
    • The nucleotide sequence of pACYC184
    • Rose, R. E. (1988) The nucleotide sequence of pACYC184, Nucleic Acids Res. 16, 355.
    • (1988) Nucleic Acids Res. , vol.16 , pp. 355
    • Rose, R.E.1
  • 23
    • 0034947940 scopus 로고    scopus 로고
    • Integration of PCR fragments at any specific site within cloning vectors without the use of restriction enzymes and DNA ligase
    • Geiser, M., Gebe, R., Drewello, D., and Schmitz, R. (2001) Integration of PCR fragments at any specific site within cloning vectors without the use of restriction enzymes and DNA ligase, BioTechniques 31, 88-90, 92.
    • (2001) BioTechniques , vol.31 , pp. 88-90
    • Geiser, M.1    Gebe, R.2    Drewello, D.3    Schmitz, R.4
  • 24
    • 0035955547 scopus 로고    scopus 로고
    • Substrate-triggered recruitment of the TolC channel-tunnel during type I export of hemolysin by Escherichia coli
    • Balakrishnan, L., Hughes, C., and Koronakis, V. (2001) Substrate-triggered recruitment of the TolC channel-tunnel during type I export of hemolysin by Escherichia coli, J. Mol. Biol. 313, 501-510.
    • (2001) J. Mol. Biol. , vol.313 , pp. 501-510
    • Balakrishnan, L.1    Hughes, C.2    Koronakis, V.3
  • 25
    • 0033940002 scopus 로고    scopus 로고
    • Cross-linked complex between oligomeric periplasmic lipoprotein AcrA and the inner-membrane-associated multidrug efflux pump AcrB from Escherichia coli
    • Zgurskaya, H. I., and Nikaido, H. (2000) Cross-linked complex between oligomeric periplasmic lipoprotein AcrA and the inner-membrane-associated multidrug efflux pump AcrB from Escherichia coli, J. Bacteriol. 182, 4264-4267.
    • (2000) J. Bacteriol. , vol.182 , pp. 4264-4267
    • Zgurskaya, H.I.1    Nikaido, H.2
  • 26
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during the assembly of the head of bacteriophage T4
    • Laemmli, U. K. (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4, Nature 227, 680-685.
    • (1970) Nature , vol.227 , pp. 680-685
    • Laemmli, U.K.1
  • 27
    • 0009482260 scopus 로고
    • Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: Procedure and some applications
    • Towbin, H., Staehelin, T., and Gordon, J. (1979) Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: Procedure and some applications, Proc. Natl. Acad. Sci. U.S.A. 76, 4350-4354.
    • (1979) Proc. Natl. Acad. Sci. U.S.A. , vol.76 , pp. 4350-4354
    • Towbin, H.1    Staehelin, T.2    Gordon, J.3
  • 29
    • 0029831354 scopus 로고    scopus 로고
    • Overlaps and parallels in the regulation of intrinsic multiple-antibiotic resistance in Escherichia coli
    • Miller, P. F., and Sulavik, M. C. (1996) Overlaps and parallels in the regulation of intrinsic multiple-antibiotic resistance in Escherichia coli, Mol. Microbiol. 21, 441-448.
    • (1996) Mol. Microbiol. , vol.21 , pp. 441-448
    • Miller, P.F.1    Sulavik, M.C.2
  • 30
    • 0036267595 scopus 로고    scopus 로고
    • Control of the AcrAB multidrug efflux pump by quorum-sensing regulator SdiA
    • Rahmati, S., Yang, S., Davidson, A. L., and Zechiedrich, E. L. (2002) Control of the AcrAB multidrug efflux pump by quorum-sensing regulator SdiA, Mol. Microbiol. 43, 677-685.
    • (2002) Mol. Microbiol. , vol.43 , pp. 677-685
    • Rahmati, S.1    Yang, S.2    Davidson, A.L.3    Zechiedrich, E.L.4
  • 31
    • 0037154424 scopus 로고    scopus 로고
    • Increased expression of the multidrug efflux genes acrAB occurs during slow growth of Escherichia coli
    • Rand, J. D., Danby, S. G., Greenway, D. L., and England, R. R. (2002) Increased expression of the multidrug efflux genes acrAB occurs during slow growth of Escherichia coli, FEMS Microbiol. Lett. 207, 91-95.
    • (2002) FEMS Microbiol. Lett. , vol.207 , pp. 91-95
    • Rand, J.D.1    Danby, S.G.2    Greenway, D.L.3    England, R.R.4
  • 32
    • 0037898916 scopus 로고    scopus 로고
    • Bile salts and fatty acids induce the expression of Escherichia coli AcrAB multidrug efflux pump through their interaction with Rob regulatory protein
    • Rosenberg, E. Y., Bertenthal, D., Nilles, M. L., Bertrand, K. P., and Nikaido, H. (2003) Bile salts and fatty acids induce the expression of Escherichia coli AcrAB multidrug efflux pump through their interaction with Rob regulatory protein, Mol. Microbiol. 48, 1609-1619.
    • (2003) Mol. Microbiol. , vol.48 , pp. 1609-1619
    • Rosenberg, E.Y.1    Bertenthal, D.2    Nilles, M.L.3    Bertrand, K.P.4    Nikaido, H.5
  • 33
  • 34
    • 0031962577 scopus 로고    scopus 로고
    • Expression of Pseudomonas aeruginosa multidrug efflux pumps MexA-MexB-OprM and MexC-MexD-OprJ in a multidrug-sensitive Escherichia coli strain
    • Srikumar, R., Kon, T., Gotoh, N., and Poole, K. (1998) Expression of Pseudomonas aeruginosa multidrug efflux pumps MexA-MexB-OprM and MexC-MexD-OprJ in a multidrug-sensitive Escherichia coli strain, Antimicrob. Agents Chemother. 42, 65-71.
    • (1998) Antimicrob. Agents Chemother. , vol.42 , pp. 65-71
    • Srikumar, R.1    Kon, T.2    Gotoh, N.3    Poole, K.4
  • 35
    • 0036889445 scopus 로고    scopus 로고
    • Chimeric analysis of the multicomponent multidrug efflux transporters from Gram-negative bacteria
    • Tikhonova, E. B., Wang, Q., and Zgurskaya, H. I. (2002) Chimeric analysis of the multicomponent multidrug efflux transporters from Gram-negative bacteria, J. Bacteriol. 184, 6499-6507.
    • (2002) J. Bacteriol. , vol.184 , pp. 6499-6507
    • Tikhonova, E.B.1    Wang, Q.2    Zgurskaya, H.I.3
  • 36
    • 33744748622 scopus 로고    scopus 로고
    • Isolation and characterization of VceC gain-of-function mutants that can function with the AcrAB multiple-drug-resistant efflux pump of Escherichia coli
    • Vediyappan, G., Borisova, T., and Fralick, J. A. (2006) Isolation and characterization of VceC gain-of-function mutants that can function with the AcrAB multiple-drug-resistant efflux pump of Escherichia coli, J. Bacteriol. 188, 3757-3762.
    • (2006) J. Bacteriol. , vol.188 , pp. 3757-3762
    • Vediyappan, G.1    Borisova, T.2    Fralick, J.A.3
  • 37
    • 9944247705 scopus 로고    scopus 로고
    • Three's company: Component structures bring a closer view of tripartite drug efflux pumps
    • Eswaran, J., Koronakis, E., Higgins, M. K., Hughes, C., and Koronakis, V. (2004) Three's company: Component structures bring a closer view of tripartite drug efflux pumps, Curr. Opin. Struct. Biol. 74, 741-747.
    • (2004) Curr. Opin. Struct. Biol. , vol.74 , pp. 741-747
    • Eswaran, J.1    Koronakis, E.2    Higgins, M.K.3    Hughes, C.4    Koronakis, V.5
  • 38
    • 0037459244 scopus 로고    scopus 로고
    • Locking TolC entrance helices to prevent protein translocation by the bacterial type I export apparatus
    • Eswaran, J., Hughes, C., and Koronakis, V. (2003) Locking TolC entrance helices to prevent protein translocation by the bacterial type I export apparatus, J. Mol. Biol. 327, 309-315.
    • (2003) J. Mol. Biol. , vol.327 , pp. 309-315
    • Eswaran, J.1    Hughes, C.2    Koronakis, V.3
  • 40
    • 3242890387 scopus 로고    scopus 로고
    • Interactions underlying assembly of the Escherichia coli AcrAB-TolC multidrug efflux system
    • Touze, T., Eswaran, J., Bokma, E., Koronakis, E., Hughes, C., and Koronakis, V. (2004) Interactions underlying assembly of the Escherichia coli AcrAB-TolC multidrug efflux system, Mol. Microbiol. 53, 697-706.
    • (2004) Mol. Microbiol. , vol.53 , pp. 697-706
    • Touze, T.1    Eswaran, J.2    Bokma, E.3    Koronakis, E.4    Hughes, C.5    Koronakis, V.6
  • 41
    • 0041659129 scopus 로고    scopus 로고
    • Linkage of the efflux-pump expression level with substrate extrusion rate in the MexAB-OprM efflux pump of Pseudomonas aeruginosa
    • Narita, S., Eda, S., Yoshihara, E., and Nakae, T. (2003) Linkage of the efflux-pump expression level with substrate extrusion rate in the MexAB-OprM efflux pump of Pseudomonas aeruginosa, Biochem. Biophys. Res. Commun. 308, 922-926.
    • (2003) Biochem. Biophys. Res. Commun. , vol.308 , pp. 922-926
    • Narita, S.1    Eda, S.2    Yoshihara, E.3    Nakae, T.4
  • 42
    • 0034304901 scopus 로고    scopus 로고
    • Chunnel vision. Export and efflux through bacterial channel-tunnels
    • Andersen, C., Hughes, C., and Koronakis, V. (2000) Chunnel vision. Export and efflux through bacterial channel-tunnels, EMBO Rep. 1, 313-318.
    • (2000) EMBO Rep. , vol.1 , pp. 313-318
    • Andersen, C.1    Hughes, C.2    Koronakis, V.3
  • 43
    • 0028804960 scopus 로고
    • Domain structure of the outer membrane transporter protein CyaE of Bordetella pertussis
    • Gross, R. (1995) Domain structure of the outer membrane transporter protein CyaE of Bordetella pertussis, Mol. Microbiol. 17, 1219-1220.
    • (1995) Mol. Microbiol. , vol.17 , pp. 1219-1220
    • Gross, R.1
  • 44
    • 33745686037 scopus 로고    scopus 로고
    • Flexibility in a drug transport accessory protein: Molecular dynamics simulations of MexA
    • Vaccaro, L., Koronakis, V., and Sansom, M. (2006) Flexibility in a drug transport accessory protein: Molecular dynamics simulations of MexA, Biophys. J. 91, 558-564.
    • (2006) Biophys. J. , vol.91 , pp. 558-564
    • Vaccaro, L.1    Koronakis, V.2    Sansom, M.3
  • 45
    • 0021943518 scopus 로고
    • Improved M13 phage cloning vectors and host strains: Nucleotide sequences of the M13mp18 and pUC19 vectors
    • Yanisch-Perron, C., Vieira, J., and Messing, J. (1985) Improved M13 phage cloning vectors and host strains: Nucleotide sequences of the M13mp18 and pUC19 vectors, Gene 33, 103-119.
    • (1985) Gene , vol.33 , pp. 103-119
    • Yanisch-Perron, C.1    Vieira, J.2    Messing, J.3


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