Structure of TolC, the outer membrane component of the bacterial type I efflux system, derived from two-dimensional crystals

Molecular Microbiology

Volumn 23, Issue 3, 1997, Pages 617-626

  Koronakis, Vassilis ^a   Li, Jade ^b   Koronakis, Eva ^a   Stauffer, Kathrin ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

OUTER MEMBRANE PROTEIN;

ARTICLE; CONTROLLED STUDY; ESCHERICHIA COLI; NONHUMAN; OUTER MEMBRANE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN STRUCTURE;

EID: 0031014882     PISSN: 0950382X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2958.1997.d01-1880.x     Document Type: Article

References (37)

1. Amos, L.A., Henderson R., and Unwin, P.N.T. (1982) 3-dimensional structure determination by electron-microscopy of 2-dimensional crystals. Prog Biophys Mol Biol 39: 183-231.
2. Benz, R., Maier, E., and Gentschev, I. (1993) ToIC of Escherichia coli functions as an outer membrane channel. Int J Med Microbiol Virol Parasitol Infect Dis 278: 187-196.
3. Crowther, R.A., Henderson, R., and Smith, J.M. (1996) MRC image-processing programs. J Struct Biol 116: 9-16.
4. Davies, J.K., and Reeves, P. (1975) Genetics of resistance to colicins in Escherichia coli K-12: cross-resistance among colicins of group A. J Bacteriol 123: 102-117.
5. Dinh, T., Paulsen, I.T., and Saier, M.H. (1994) A family of extracytoplasmic proteins that allow transport of large molecules across the outer membranes of Gram-negative bacteria. J Bacteriol 176: 3825-3831.
6. Dorset, D.L., Engel, A., Haner, A., Massalski, A., and Rosenbush, J.P. (1983) Two-dimensional crystal packing of matrix porin. A channel forming protein in Escherichia coli outer membranes. J Mol Biol 165: 701-710.
7. Dorset, D.L, Massalski, A.K., and Rosenbusch, J.P. (1989) In-plane phase transition of an integral membrane protein: nucleation of the OmpF matrix porin rectangular polymorph. Proc Natl Acad Sci USA 86: 6143-6147.
8. Eisenberg, D., Schwarz, E., Komaromy, M., and Wall, R. (1984) Analysis of membrane and surface protein sequences with the hydrophobic moment plot. J Mol Biol 179: 125-142.
9. Fralick, J.A. (1996) Evidence that ToIC is required for functioning of the Mar/AcrAB efflux pump of Escherichia coli. J Bacteriol 178: 5803-5805.
10. Glaser, P., Sakamoto, H., Bellalou, J., Ullmann, A., and Danchin, A. (1988) Secretion of cyclolysin, the calmodulin-sensitive adenylate cyclase-haemolysin bifunctional protein of Bordetella pertussis. EMBO J 7: 3997-4004.
11. Guzzo, J., Murgier, M., Filoux, A., and Lazdunski, A. (1990) Cloning of the Pseudomonas aeruginosa alkaline protease gene and secretion of the protease into the medium by Escherichia coli. J Bacteriol 172: 942-948.
12. Henderson, R., Baldwin, J.M., Downing, K., Lepault, J., and Zemlin, F. (1986) Structure of purple membrane from Halobacterium halobium: recording, measurement and evaluation of electron-micrographs at 3.5Å resolution. Ultramicroscopy 19: 147-178.
13. Hiraga, S., Niki, H., Ogura, T., Ichinose, C., Mori, H., Ezaki, B., and Jaffe, A. (1989) Chromosome partitioning in Escherichia coli: novel mutants producing anucleate cells. J Bacteriol 171: 1496-1505.
14. Jap, B.K. (1988) High-resolution electron diffraction of reconstituted PhoE porin. J Mol Biol 199: 229-231.
15. Jeanteur, D., Lakey, J.H., and Pattus, F. (1991) The bacterial porin superfamily: sequence alignment and structure prediction. Mol Microbiol 5: 2153-2164.
16. Koronakis, V., and Hughes, C. (1993) Bacterial signal peptide-independent protein export: HlyB-directed secretion of hemolysin. Semin Cell Biol 4: 7-15.
17. Koronakis, V., Koronakis, E., and Hughes, C. (1989) Isolation and analysis of the C-terminal signal directing export of Escherichia coli hemolysin protein across both bacterial membranes. EMBO J 8: 595-605.
18. Koronakis, V., Hughes, C., and Koronakis, E. (1991) Energetically distinct early and late stages of HlyB/HlyD-dependent secretion across both Escherichia coli membranes. EMBO J 10: 3263-3272.
19. Lepault, J., Dargent, B., Tichelaar, W., Rosenbusch, J.P., Leonard, K., and Pattus, F. (1988) Three-dimensional reconstruction of maltoporin from electron microscopy and image processing. EMBO J 7: 261-268.
20. Letoffe, S., Delepelaire, P., and Wandersman, C. (1990) Protease secretion by Erwinia chrysanthemi: the specific secretion functions are analogous to those of Escherichia coli alpha-haemolysin. EMBO J 9: 1375-1382.
21. Li, X.Z., Nikaido, H., and Poole, K. (1995) Role of mexA-mexB-oprM in antibiotic efflux in Pseudomonas aeruginosa. Antimicrob Agents Chemother 39: 1948-1953.
22. Ma, D., Cook, D.N., Hearst, J.E., and Nikaido, H. (1994) Efflux pumps and drug resistance in Gram-negative bacteria. Trends Microbiol 2: 489-493.
23. Morona, R., Manning, P.A., and Reeves, P. (1983) Identification and characterization of the ToIC protein, an outer membrane protein from Escherichia coli. J Bacteriol 153: 693-699.
24. Nagel de Zwaig, R., and Luria, S.E. (1967) Genetics and physiology of colicin-tolerant mutants of Escherichia coli. J Bacteriol 94: 1112-1123.
25. Nikaido, H., (1994) Prevention of drug access to bacterial targets: permeability barriers and active efflux. Science 264: 382-387.
26. Poole, K., Krebes, K., McNally, C., and Nashat, S. (1993) Multiple antibiotic resistance in Pseudomonas aeruginosa: evidence for involvement of an efflux operon. J Bacteriol 175: 7363-7372.
27. Rivilla, R., Sutton, J.M., and Downie, J.A. (1995) Rhizobium leguminosarum NodT is related to a family of outer-membrane transport proteins that includes ToIC, PrtF, CyaE and AprF. Gene 161: 27-31.
28. Schatz, G., and Dobberstein, B. (1996) Common principles of protein translocation across membranes. Science 271: 1519-1526.
29. Schirmer, T., and Cowan, S.W. (1993) Prediction of membrane-spanning beta-strands and its application to maltoporin. Protein Sci 2: 1361-1363.
30. Stauffer, K.A., Hoenger, A., and Engel, A. (1992) Two-dimensional crystals of Escherichia coli maltoporin and their interaction with the maltose-binding protein. J Mol Biol 223: 1155-1165.
31. Stone, B.J., and Miller, V.L. (1995) Salmonella enteritidis has a homologue of ToIC that is required for virulence in BALB/ c mice. Mol Microbiol 17: 701-712.
32. Studier, W., and Moffat, B.A. (1986) Use of bacteriophage T7 RNA polymerase to direct selective high-level expression of cloned genes. J Mol Biol 189: 113-130.
33. Unwin, N. (1995) Acetylcholin receptor channel imaged in the open state. Nature 373: 37-43.
34. Valpuesta, J.M., Carrascosa, J.L., and Henderson, R. (1994) Analysis of electron microscope images and electron diffraction patterns of thin crystals of phi 29 connectors in ice. J Mol Biol 240: 281-287.
35. Wagner, W., Vogel, M., and Goebel, W. (1983) Transport of hemolysin across the outer membrane of Escherichia coli requires two functions. J Bacteriol 154: 200-210.
36. Wandersman, C., and Delepelaire, P. (1990) ToIC, an Escherichia coli outer membrane protein required for hemolysin secretion. Proc Natl Acad Sci USA 87: 4776-4780.
37. Wilmsen, H.U., Leonard, K.R., Tichelaar, W., Buckley, J.T., and Pattus, F. (1992) The aerolysin membrane channel is formed by heptamerization of the monomer. EMBO J 11: 2457-2463.